DK0629203T3 - Desosaminoderivater af makrolider som immunosuppressive midler og antifungale midler - Google Patents

Desosaminoderivater af makrolider som immunosuppressive midler og antifungale midler

Info

Publication number
DK0629203T3
DK0629203T3 DK93903553T DK93903553T DK0629203T3 DK 0629203 T3 DK0629203 T3 DK 0629203T3 DK 93903553 T DK93903553 T DK 93903553T DK 93903553 T DK93903553 T DK 93903553T DK 0629203 T3 DK0629203 T3 DK 0629203T3
Authority
DK
Denmark
Prior art keywords
macrolides
pct
immunosuppressants
antifungal agents
desosamine
Prior art date
Application number
DK93903553T
Other languages
English (en)
Inventor
R Hauske James
R Schulte Gary
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0629203T3 publication Critical patent/DK0629203T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93903553T 1992-03-02 1993-01-27 Desosaminoderivater af makrolider som immunosuppressive midler og antifungale midler DK0629203T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84435092A 1992-03-02 1992-03-02
PCT/US1993/000426 WO1993018042A1 (en) 1992-03-02 1993-01-27 Desosamino derivatives of macrolides as immunosuppressants and antifungal agents

Publications (1)

Publication Number Publication Date
DK0629203T3 true DK0629203T3 (da) 2001-11-12

Family

ID=25292478

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93903553T DK0629203T3 (da) 1992-03-02 1993-01-27 Desosaminoderivater af makrolider som immunosuppressive midler og antifungale midler

Country Status (12)

Country Link
US (2) US5506233A (da)
EP (1) EP0629203B1 (da)
JP (1) JPH07500613A (da)
AT (1) ATE205496T1 (da)
CA (1) CA2131371A1 (da)
DE (1) DE69330747T2 (da)
DK (1) DK0629203T3 (da)
ES (1) ES2160593T3 (da)
FI (1) FI944014A0 (da)
GR (1) GR3037059T3 (da)
PT (1) PT629203E (da)
WO (1) WO1993018042A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2182004C1 (ru) * 2001-02-22 2002-05-10 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Лекарственный препарат для парентерального применения
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US7452692B2 (en) * 2002-02-13 2008-11-18 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Method for extracting a macrolide from biomatter
MXPA04007847A (es) 2002-02-13 2005-02-24 Biogal Gyogyszergyar Metodo para extraer un macrolido de biomateria.
US20060169199A1 (en) * 2003-03-31 2006-08-03 Vilmos Keri Crystallization and purification of macrolides
ES2229975T1 (es) * 2003-03-31 2005-05-01 Teva Gyogyszergyar Reszvenytarsasag Cristalizacion y purificacion de macrolidos.
US7160867B2 (en) * 2003-05-16 2007-01-09 Isotechnika, Inc. Rapamycin carbohydrate derivatives
DK1558622T3 (da) * 2003-07-24 2008-02-25 Teva Gyogyszergyar Zartkoeruee Fremgangsmåde til oprensning af macrolider
CA2571710A1 (en) 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
MX2007005867A (es) * 2004-12-22 2007-07-04 Teva Gyogyszergyar Zartkoeruen Mukoedo Reszvenytarsasag Metodo de purificar macrolidos.
US20060154953A1 (en) * 2005-01-05 2006-07-13 Vilmos Keri Amorphous tacrolimus and preparation thereof
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
DE602007006601D1 (de) * 2006-03-15 2010-07-01 Teva Gyogyszergyar Zartkoeruee Verfahren zur reinigung von tacrolimus
JP2009203162A (ja) * 2006-06-05 2009-09-10 Astellas Pharma Inc マクロライド化合物の新規製造法
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
EP4218718A3 (en) 2009-05-06 2024-04-24 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
AU6286690A (en) * 1989-08-18 1991-04-03 Fisons Plc Macrocyclic compounds
IE904050A1 (en) * 1989-11-13 1991-05-22 Merck & Co Inc Aminomacrolides and derivatives having immunosuppressive¹activity
EP0466365A3 (en) * 1990-07-03 1992-04-15 Merck & Co. Inc. Novel immunosuppressant fermentation products of a microorganism

Also Published As

Publication number Publication date
DE69330747D1 (de) 2001-10-18
EP0629203A1 (en) 1994-12-21
US5563135A (en) 1996-10-08
ES2160593T3 (es) 2001-11-16
EP0629203B1 (en) 2001-09-12
DE69330747T2 (de) 2002-05-29
FI944014A (fi) 1994-09-01
US5506233A (en) 1996-04-09
FI944014A0 (fi) 1994-09-01
PT629203E (pt) 2002-01-30
GR3037059T3 (en) 2002-01-31
ATE205496T1 (de) 2001-09-15
CA2131371A1 (en) 1993-09-16
JPH07500613A (ja) 1995-01-19
WO1993018042A1 (en) 1993-09-16

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