KR20060096995A - 중성구 엘라스타제 억제제로서의 2-피리돈 유도체 및 그의용도 - Google Patents

중성구 엘라스타제 억제제로서의 2-피리돈 유도체 및 그의용도 Download PDF

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Publication number
KR20060096995A
KR20060096995A KR1020067005458A KR20067005458A KR20060096995A KR 20060096995 A KR20060096995 A KR 20060096995A KR 1020067005458 A KR1020067005458 A KR 1020067005458A KR 20067005458 A KR20067005458 A KR 20067005458A KR 20060096995 A KR20060096995 A KR 20060096995A
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KR
South Korea
Prior art keywords
phenyl
oxo
methyl
trifluoromethyl
alkyl
Prior art date
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Withdrawn
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KR1020067005458A
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English (en)
Korean (ko)
Inventor
페터 한센
카롤리나 라위츠
한스 뢴
안토니오스 니키티디스
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아스트라제네카 아베
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29212489&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20060096995(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 아스트라제네카 아베 filed Critical 아스트라제네카 아베
Publication of KR20060096995A publication Critical patent/KR20060096995A/ko
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
KR1020067005458A 2003-09-18 2004-09-15 중성구 엘라스타제 억제제로서의 2-피리돈 유도체 및 그의용도 Withdrawn KR20060096995A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0302487-4 2003-09-18
SE0302487A SE0302487D0 (sv) 2003-09-18 2003-09-18 Novel compounds

Publications (1)

Publication Number Publication Date
KR20060096995A true KR20060096995A (ko) 2006-09-13

Family

ID=29212489

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067005458A Withdrawn KR20060096995A (ko) 2003-09-18 2004-09-15 중성구 엘라스타제 억제제로서의 2-피리돈 유도체 및 그의용도

Country Status (25)

Country Link
US (1) US20070043036A1 (enExample)
EP (1) EP1663974B1 (enExample)
JP (1) JP2007505902A (enExample)
KR (1) KR20060096995A (enExample)
CN (1) CN100439339C (enExample)
AR (1) AR046083A1 (enExample)
AT (1) ATE420861T1 (enExample)
AU (1) AU2004272485B2 (enExample)
BR (1) BRPI0414570A (enExample)
CA (1) CA2538410A1 (enExample)
CO (1) CO5670357A2 (enExample)
DE (1) DE602004019110D1 (enExample)
ES (1) ES2319300T3 (enExample)
IL (1) IL173986A0 (enExample)
IS (1) IS8394A (enExample)
MX (1) MXPA06002723A (enExample)
NO (1) NO20061700L (enExample)
RU (1) RU2348617C2 (enExample)
SA (1) SA04250300B1 (enExample)
SE (1) SE0302487D0 (enExample)
TW (1) TW200526579A (enExample)
UA (1) UA84878C2 (enExample)
UY (1) UY28513A1 (enExample)
WO (1) WO2005026124A1 (enExample)
ZA (1) ZA200602262B (enExample)

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Also Published As

Publication number Publication date
CO5670357A2 (es) 2006-08-31
SA04250300B1 (ar) 2008-09-07
NO20061700L (no) 2006-04-18
HK1089167A1 (en) 2006-11-24
CN1856467A (zh) 2006-11-01
RU2006112427A (ru) 2007-11-10
CA2538410A1 (en) 2005-03-24
SE0302487D0 (sv) 2003-09-18
ZA200602262B (en) 2007-07-25
DE602004019110D1 (de) 2009-03-05
UA84878C2 (ru) 2008-12-10
AR046083A1 (es) 2005-11-23
ES2319300T3 (es) 2009-05-06
AU2004272485B2 (en) 2008-03-13
BRPI0414570A (pt) 2006-11-07
EP1663974A1 (en) 2006-06-07
ATE420861T1 (de) 2009-01-15
RU2348617C2 (ru) 2009-03-10
TW200526579A (en) 2005-08-16
JP2007505902A (ja) 2007-03-15
WO2005026124A1 (en) 2005-03-24
CN100439339C (zh) 2008-12-03
US20070043036A1 (en) 2007-02-22
EP1663974B1 (en) 2009-01-14
IS8394A (is) 2006-03-31
IL173986A0 (en) 2006-07-05
UY28513A1 (es) 2005-04-29
MXPA06002723A (es) 2006-06-06
AU2004272485A1 (en) 2005-03-24

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PA0105 International application

Patent event date: 20060317

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid