KR20040030728A - 햇빛에 의해 손상된 피부를 치료하기 위한 크림 - Google Patents
햇빛에 의해 손상된 피부를 치료하기 위한 크림 Download PDFInfo
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- KR20040030728A KR20040030728A KR10-2003-7017319A KR20037017319A KR20040030728A KR 20040030728 A KR20040030728 A KR 20040030728A KR 20037017319 A KR20037017319 A KR 20037017319A KR 20040030728 A KR20040030728 A KR 20040030728A
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- KR
- South Korea
- Prior art keywords
- weight
- cream
- vehicle
- lipoic acid
- skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A61K8/355—Quinones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Abstract
Description
Claims (6)
- 유리 라디칼의 작용에 관여하고, 세포의 에너지 생성에 작용하는 과정에 의한 광손상된 피부를 국부적으로 치료하기 위한 페이셜 크림으로서, 크림의 활성 성분이 안정화 비히클에 함유되고,0.5 내지 7중량%의 D,L-α-리포산, 0.05 내지 0.5중량%의 조효소 Q-10, 및 0.01 내지 3중량%의 아세틸-L-카르니틴 히드로클로라이드가 활성 성분을 구성하며, 이로써 복합적 상승 효과를 가짐을 특징으로 하는 크림.
- 제 1항에 있어서, 5중량%의 D,L-α-리포산, 0.3중량%의 조효소 Q-10, 및 0.03중량%의 아세틸-L-카르니틴 히드로클로라이드가 활성 성분을 구성함을 특징으로 하는 크림.
- 제 1항에 있어서, 1중량%의 D,L-α-리포산, 0.3중량%의 조효소 Q-10, 및 0.03중량%의 아세틸-L-카르니틴 히드로클로라이드가 활성 성분을 구성함을 특징으로 하는 크림.
- 크림의 활성 성분을 분산시키고 에멀션화시킬 수 있으며, 크림에 보습성, 유연성, 안정성, 보존성 및 피부 침투성을 부가하는, 제 1항 내지 제 3항 중의 어느 한 항에 따른 크림의 기본 제제를 형성하기 위한 비히클로서, 비히클의 성분이 20내지 80중량%의 물, 5 내지 50중량%의 2% 수용액 중의 크산탄검, 1 내지 40중량%의 카프릴산/카프르산 트리글리세라이드, 1 내지 25중량%의 프루누스 둘시스 오일(Prunus dulcis oil), 0.5 내지 10중량%의 PEG-75 스테아레이트, 0.5 내지 10중량의 글리세릴 스테아레이트, 1 내지 10중량%의 세테아릴 알코올, 1 내지 10중량%의 디메티콘, 1 내지 15중량의 글리세린, 0.1 내지 1.0중량%의 페녹시에탄올, 0.05 내지 1.0중량%의 메틸파라벤, 0.005 내지 0.5중량%의 부틸파라벤, 0.005 내지 0.5중량%의 에틸파라벤, 0.005 내지 0.5중량%의 프로필파라벤, 0.005 내지 0.5중량%의 이소부틸파라벤, 0.05 내지 5중량%의 10% 수용액 중의 수산화나트륨, 0.05 내지 5중량%의 퍼퓸, 0.05 내지 5중량%의 카르보머를 포함함을 특징으로 하는 비히클.
- 제 4항에 있어서, 상기 성분들의 적합한 양이 46.32%의 물, 15.0중량%의 2% 수용액 중의 크산탄검, 13.0중량%의 카프릴산/카프르산 트리글리세라이드, 4.0중량%의 프루누스 둘시스 오일, 3.3중량%의 PEG-75 스테아레이트, 2.7중량%의 글리세릴 스테아레이트, 3.0중량%의 세테아릴 알코올, 3.0중량%의 디메티콘, 3.0중량%의 글리세린, 0.355중량%의 페녹시에탄올, 0.085중량%의 메틸파라벤, 0.02중량%의 부틸파라벤, 0.02중량%의 에틸파라벤, 0.01중량%의 프로필파라벤, 0.01중량%의 이소부틸파라벤, 0.4중량%의 10% 수용액 중의 수산화나트륨, 0.25중량%의 퍼퓸, 0.2중량%의 카르보머임을 특징으로 하는 비히클.
- 제 1항 내지 제 5항 중의 어느 한 항에 따른 크림 제제의 비히클에 D,L-α-리포산을 분산시키고 에멀션화시키는 방법으로서, 나머지 성분들과 혼합하기 전에, D,L-α-리포산을 카프릴산/카프르산 트리글리세라이드에 용해시킨 후, D,L-α-리포산과 카프릴산/트리글리세라이드의 혼합물을 비히클에 첨가함을 특징으로 하는 방법.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0102380-3 | 2001-07-02 | ||
SE0102380A SE0102380D0 (sv) | 2001-07-02 | 2001-07-02 | Kräm för behandling av åldersförändringar i huden hos människa |
PCT/SE2002/001308 WO2003037291A1 (en) | 2001-07-02 | 2002-06-30 | Cream for treatment of skin injured by the sun |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20040030728A true KR20040030728A (ko) | 2004-04-09 |
KR100885347B1 KR100885347B1 (ko) | 2009-02-26 |
Family
ID=20284723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020037017319A KR100885347B1 (ko) | 2001-07-02 | 2002-06-30 | 햇빛에 의해 손상된 피부를 치료하기 위한 크림 |
Country Status (20)
Country | Link |
---|---|
US (2) | US20050152856A2 (ko) |
EP (1) | EP1411889B1 (ko) |
JP (1) | JP2005507406A (ko) |
KR (1) | KR100885347B1 (ko) |
CN (1) | CN1713888B (ko) |
AT (1) | ATE349998T1 (ko) |
AU (1) | AU2002318699B2 (ko) |
BR (1) | BR0210760A (ko) |
CA (1) | CA2450726A1 (ko) |
CY (1) | CY1107600T1 (ko) |
DE (1) | DE60217356T2 (ko) |
DK (1) | DK1411889T3 (ko) |
ES (1) | ES2280554T3 (ko) |
MX (1) | MXPA03011509A (ko) |
NO (1) | NO20035715D0 (ko) |
NZ (1) | NZ530226A (ko) |
PT (1) | PT1411889E (ko) |
RU (1) | RU2313333C2 (ko) |
SE (1) | SE0102380D0 (ko) |
WO (1) | WO2003037291A1 (ko) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2858932B1 (fr) * | 2003-08-22 | 2009-10-30 | Oreal | Composition destinee a lutter contre la degradation des fibres de collagene induite en condition d'exposition solaire naturelle |
CA3031283A1 (en) | 2004-01-22 | 2005-08-04 | University Of Miami | Topical co-enzyme q10 formulations and methods of use |
US7776915B2 (en) * | 2005-03-24 | 2010-08-17 | Tracie Martyn International, Llc | Topical formulations and methods of use |
CN1723881A (zh) * | 2005-06-23 | 2006-01-25 | 马开龙 | 含辅酶q10的治疗皮肤病的组合物及其制备方法 |
MX337408B (es) | 2007-03-22 | 2016-03-03 | Berg Llc | Formulaciones topicas que tienen biodisponibilidad aumentada. |
US7999040B2 (en) * | 2007-09-25 | 2011-08-16 | Nanochem Solutions, Inc. | Method of making graft copolymers from sodium poly(aspartate) and the resulting graft copolymer |
KR101715631B1 (ko) * | 2008-04-01 | 2017-03-13 | 안티포딘 파마슈티칼스, 인코포레이티드 | 피부 관리를 위한 조성물 및 방법 |
EP2271325A4 (en) | 2008-04-11 | 2011-11-09 | Cytotech Labs Llc | METHODS AND USE OF INDUCING APOPTOSIS IN CANCER CELLS |
KR101553074B1 (ko) | 2008-07-17 | 2015-09-14 | 가천대학교 산학협력단 | 나노에멀젼 조성물 |
KR20180056816A (ko) | 2009-05-11 | 2018-05-29 | 베르그 엘엘씨 | 환경대사적 전환인자(조효소 q10)를 사용한 질환의 치료 방법 |
EP2544663B1 (en) | 2010-03-12 | 2018-01-03 | Berg LLC | Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof |
JP6092844B2 (ja) | 2011-04-04 | 2017-03-08 | バーグ エルエルシー | 中枢神経系腫瘍の治療方法 |
MY183615A (en) | 2011-06-17 | 2021-03-03 | Berg Llc | Inhalable pharmaceutical compositions |
NZ713868A (en) | 2013-04-08 | 2021-12-24 | Berg Llc | Treatment of cancer using coenzyme q10 combination therapies |
SG10201907816RA (en) | 2013-09-04 | 2019-09-27 | Berg Llc | Methods of treatment of cancer by continuous infusion of coenzyme q10 |
WO2020201377A1 (en) | 2019-04-04 | 2020-10-08 | Medica Clinical Nord Sverige Ab | Cream for treatment of skin injured by the sun |
SE543528C2 (en) * | 2019-04-04 | 2021-03-16 | Medica Clinical Nord Sverige Ab | Cream for treatment of skin injured by the sun |
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JPS62175415A (ja) * | 1986-01-27 | 1987-08-01 | Kanebo Ltd | 皮膚化粧料 |
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DE4410238A1 (de) * | 1994-03-25 | 1995-09-28 | Beiersdorf Ag | Hautpflegemittel |
AU6482596A (en) * | 1995-07-03 | 1997-02-05 | Wilson T. Crandall | Transdermal and oral treatment of androgenic alopecia |
DE19537027A1 (de) * | 1995-10-05 | 1997-04-10 | Beiersdorf Ag | Hautpflegemittel für alte Haut |
US5667791A (en) | 1996-05-31 | 1997-09-16 | Thione International, Inc. | X-ray induced skin damage protective composition |
US5977162A (en) * | 1996-09-16 | 1999-11-02 | Seidman; Michael D. | Therapeutic treatment for auditory function |
US6015548A (en) * | 1998-07-10 | 2000-01-18 | Shaklee Corporation | High efficiency skin protection formulation with sunscreen agents and antioxidants |
DE19806947A1 (de) * | 1998-02-19 | 1999-08-26 | Beiersdorf Ag | Kosmetische oder dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Chinon und oder mindestens einem Hydrochinon sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen |
DE19806889A1 (de) * | 1998-02-19 | 1999-08-26 | Beiersdorf Ag | Verwendung von Acyl-Carnitin |
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JP2000063273A (ja) * | 1998-08-20 | 2000-02-29 | Noevir Co Ltd | 免疫機能低下抑制剤 |
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ATE320833T1 (de) * | 2000-06-06 | 2006-04-15 | Verwendung von einem liponsaüren -(r)- enantiomeren in kosmetika und dermatologie | |
DE10036797A1 (de) * | 2000-07-28 | 2002-02-07 | Beiersdorf Ag | Verwendung von Kombinationen mit einem Gehalt an Carnitinen |
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DE10059584A1 (de) * | 2000-11-30 | 2002-06-06 | Beiersdorf Ag | Kosmetische oder dermatologische getränkte Tücher |
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DE10111048A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von alpha-Liponsäure zur Herstellung kosmetischer oder dermatologischer Zubereitungen zur Regeneration beanspruchter Haut, insbesondere der gealterten Haut |
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2001
- 2001-07-02 SE SE0102380A patent/SE0102380D0/xx unknown
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2002
- 2002-06-30 WO PCT/SE2002/001308 patent/WO2003037291A1/en active IP Right Grant
- 2002-06-30 NZ NZ530226A patent/NZ530226A/en not_active IP Right Cessation
- 2002-06-30 DK DK02747792T patent/DK1411889T3/da active
- 2002-06-30 MX MXPA03011509A patent/MXPA03011509A/es active IP Right Grant
- 2002-06-30 AT AT02747792T patent/ATE349998T1/de not_active IP Right Cessation
- 2002-06-30 PT PT02747792T patent/PT1411889E/pt unknown
- 2002-06-30 DE DE60217356T patent/DE60217356T2/de not_active Expired - Lifetime
- 2002-06-30 KR KR1020037017319A patent/KR100885347B1/ko active IP Right Grant
- 2002-06-30 JP JP2003539635A patent/JP2005507406A/ja active Pending
- 2002-06-30 AU AU2002318699A patent/AU2002318699B2/en not_active Expired
- 2002-06-30 RU RU2003137600/15A patent/RU2313333C2/ru not_active IP Right Cessation
- 2002-06-30 BR BR0210760-0A patent/BR0210760A/pt not_active Application Discontinuation
- 2002-06-30 EP EP02747792A patent/EP1411889B1/en not_active Expired - Lifetime
- 2002-06-30 CA CA002450726A patent/CA2450726A1/en not_active Abandoned
- 2002-06-30 CN CN028131169A patent/CN1713888B/zh not_active Expired - Lifetime
- 2002-06-30 ES ES02747792T patent/ES2280554T3/es not_active Expired - Lifetime
-
2003
- 2003-12-19 NO NO20035715A patent/NO20035715D0/no not_active Application Discontinuation
-
2004
- 2004-06-21 US US10/482,694 patent/US20050152856A2/en not_active Abandoned
-
2006
- 2006-12-21 US US11/642,948 patent/US20070212431A1/en not_active Abandoned
-
2007
- 2007-03-26 CY CY20071100415T patent/CY1107600T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
RU2003137600A (ru) | 2005-03-27 |
SE0102380D0 (sv) | 2001-07-02 |
DE60217356T2 (de) | 2007-10-11 |
RU2313333C2 (ru) | 2007-12-27 |
KR100885347B1 (ko) | 2009-02-26 |
AU2002318699B2 (en) | 2007-01-04 |
EP1411889B1 (en) | 2007-01-03 |
NO20035715D0 (no) | 2003-12-19 |
US20070212431A1 (en) | 2007-09-13 |
EP1411889A1 (en) | 2004-04-28 |
CA2450726A1 (en) | 2003-05-08 |
US20040219114A1 (en) | 2004-11-04 |
BR0210760A (pt) | 2004-07-20 |
DE60217356D1 (de) | 2007-02-15 |
CN1713888B (zh) | 2011-01-26 |
CY1107600T1 (el) | 2013-03-13 |
MXPA03011509A (es) | 2004-10-28 |
ES2280554T3 (es) | 2007-09-16 |
CN1713888A (zh) | 2005-12-28 |
JP2005507406A (ja) | 2005-03-17 |
DK1411889T3 (da) | 2007-05-07 |
WO2003037291A1 (en) | 2003-05-08 |
PT1411889E (pt) | 2007-04-30 |
WO2003037291A8 (en) | 2004-05-13 |
US20050152856A2 (en) | 2005-07-14 |
NZ530226A (en) | 2005-08-26 |
ATE349998T1 (de) | 2007-01-15 |
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