KR20040004406A - 개의 통증 및 염증을 치료하기 위한사이클로-옥시게나제-2 선택적 억제 화합물 - Google Patents

개의 통증 및 염증을 치료하기 위한사이클로-옥시게나제-2 선택적 억제 화합물 Download PDF

Info

Publication number
KR20040004406A
KR20040004406A KR10-2003-7005258A KR20037005258A KR20040004406A KR 20040004406 A KR20040004406 A KR 20040004406A KR 20037005258 A KR20037005258 A KR 20037005258A KR 20040004406 A KR20040004406 A KR 20040004406A
Authority
KR
South Korea
Prior art keywords
cox
carpropene
inhibitor
inflammatory
dogs
Prior art date
Application number
KR10-2003-7005258A
Other languages
English (en)
Korean (ko)
Inventor
크리스틴 마리에 런디
안토니 폴 리켓츠
Original Assignee
화이자 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 화이자 인코포레이티드 filed Critical 화이자 인코포레이티드
Publication of KR20040004406A publication Critical patent/KR20040004406A/ko

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
KR10-2003-7005258A 1997-05-05 1998-05-01 개의 통증 및 염증을 치료하기 위한사이클로-옥시게나제-2 선택적 억제 화합물 KR20040004406A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4563597P 1997-05-05 1997-05-05
US60/045,635 1997-05-05
PCT/IB1998/000662 WO1998050033A1 (en) 1997-05-05 1998-05-01 Cox-2 selective carprofen for treating pain and inflammation in dogs

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1019997010252A Division KR20010012300A (ko) 1997-05-05 1998-05-01 개의 통증 및 염증을 치료하기 위한 콕스-2 선택적카르프로펜

Publications (1)

Publication Number Publication Date
KR20040004406A true KR20040004406A (ko) 2004-01-13

Family

ID=21939053

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019997010252A KR20010012300A (ko) 1997-05-05 1998-05-01 개의 통증 및 염증을 치료하기 위한 콕스-2 선택적카르프로펜
KR10-2003-7005258A KR20040004406A (ko) 1997-05-05 1998-05-01 개의 통증 및 염증을 치료하기 위한사이클로-옥시게나제-2 선택적 억제 화합물

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019997010252A KR20010012300A (ko) 1997-05-05 1998-05-01 개의 통증 및 염증을 치료하기 위한 콕스-2 선택적카르프로펜

Country Status (32)

Country Link
EP (1) EP0988034A1 (es)
JP (1) JP2000513020A (es)
KR (2) KR20010012300A (es)
CN (1) CN1255059A (es)
AP (1) AP9801234A0 (es)
AR (2) AR011726A1 (es)
AU (1) AU6932198A (es)
BG (1) BG103852A (es)
BR (1) BR9808720A (es)
CA (1) CA2288759A1 (es)
DZ (1) DZ2479A1 (es)
EA (1) EA003696B1 (es)
GT (1) GT199800063A (es)
HR (1) HRP980244A2 (es)
HU (1) HUP0001286A3 (es)
ID (1) ID21311A (es)
IL (1) IL132570A0 (es)
IS (1) IS5220A (es)
MA (1) MA26491A1 (es)
NO (1) NO995389L (es)
NZ (1) NZ500183A (es)
OA (1) OA11213A (es)
PA (1) PA8450601A1 (es)
PE (1) PE72599A1 (es)
PL (1) PL337003A1 (es)
SK (1) SK148199A3 (es)
TN (1) TNSN98059A1 (es)
TW (1) TW590773B (es)
UY (1) UY24989A1 (es)
WO (1) WO1998050033A1 (es)
YU (1) YU55899A (es)
ZA (1) ZA983722B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245797B1 (en) 1997-10-22 2001-06-12 Merck & Co., Inc. Combination therapy for reducing the risks associated with cardio-and-cerebrovascular disease
AU2003204888B2 (en) * 1998-05-22 2005-07-28 Pfizer Products Inc. Treating or Preventing the Early Stages of Degeneration of Articular Cartilage or Subchondral Bone in Mammals Using Carprofen and Derivatives
US6506785B2 (en) * 1998-05-22 2003-01-14 Pfizer, Inc. Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives
EP1123091A1 (en) * 1998-10-23 2001-08-16 Merck Frosst Canada & Co. Combination product comprising an e-type prostaglandin ligand and a cox-2 selective inhibitor and methods of use
EP1637137A3 (en) * 1999-03-10 2006-07-05 G.D. Searle LLC Method and composition for administering a cyclooxygenase-2 inhibitor to animals
AU1592901A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
AU2001259974A1 (en) * 2000-05-15 2001-11-26 Merck Frosst Canada & Co Combination therapy using cox-2 selective inhibitor and thromboxane inhibitor and compositions therefor
EA200802070A1 (ru) 2000-06-13 2009-06-30 Вайет Болеутоляющее и противовоспалительные составы, содержащие ингибиторы циклооксигеназы-2
DE10032132A1 (de) * 2000-07-01 2002-01-17 Lohmann Therapie Syst Lts Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung
WO2002012549A1 (en) 2000-08-07 2002-02-14 Vanderbilt University Compositions and methods for detecting and quantifying cox-2 activity and 2-arachidonylglycerol metabolites
AU2002354901A1 (en) * 2001-07-16 2003-03-03 Edward Hogestatt Compounds with analgesic, antipyretic and/or anti-inflammatory activity
ATE342722T1 (de) 2003-05-07 2006-11-15 Osteologix As Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
KR100780983B1 (ko) * 2003-07-31 2007-11-30 파마시아 앤드 업존 캄파니 엘엘씨 소염제의 분산성 제제
EP1940380A2 (en) * 2005-05-20 2008-07-09 Pfizer Limited Synergistic combinations of non-steroidal antiinflammatory drugs with alpha-2 delta-ligands
US9114071B2 (en) 2007-04-04 2015-08-25 Sigmoid Pharma Limited Oral pharmaceutical composition
JP2010527285A (ja) 2007-04-26 2010-08-12 シグモイド・ファーマ・リミテッド 複数のミニカプセルの製造
ES2649112T3 (es) 2009-05-18 2018-01-10 Sigmoid Pharma Limited Composición que comprende gotas de aceite
WO2011018504A2 (en) 2009-08-12 2011-02-17 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
WO2015134792A1 (en) 2014-03-06 2015-09-11 Aratana Therapeutics, Inc. Compositions of grapiprant and methods for using the same
BR112017009510A2 (pt) 2014-11-07 2017-12-19 Sigmoid Pharma Ltd composições compreendendo ciclosporina
CN107106536A (zh) * 2015-01-09 2017-08-29 美洲豹动物健康公司 治疗伴侣动物的腹泻的方法
US20230174485A1 (en) * 2020-03-25 2023-06-08 Sri International Lipoxygenase inhibitors
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections
KR102404883B1 (ko) 2020-11-30 2022-06-07 (주)이노보테라퓨틱스 벤즈브로마론을 포함하는 켈로이드 또는 비대흉터 예방 또는 치료용 약학 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896145A (en) * 1972-07-24 1975-07-22 Hoffmann La Roche Carbazoles
CA1319886C (en) * 1987-02-03 1993-07-06 Alberto Ferro Mixed micelle solutions

Also Published As

Publication number Publication date
AR039628A2 (es) 2005-03-02
PL337003A1 (en) 2000-07-31
CN1255059A (zh) 2000-05-31
HRP980244A2 (en) 1999-02-28
DZ2479A1 (fr) 2003-02-01
NZ500183A (en) 2002-04-26
KR20010012300A (ko) 2001-02-15
MA26491A1 (fr) 2004-12-20
OA11213A (en) 2003-07-14
BG103852A (en) 2000-06-30
CA2288759A1 (en) 1998-11-12
NO995389L (no) 2000-01-04
GT199800063A (es) 1999-10-26
EA199900895A1 (ru) 2000-06-26
HUP0001286A2 (hu) 2000-11-28
BR9808720A (pt) 2000-07-11
ID21311A (id) 1999-05-20
SK148199A3 (en) 2001-09-11
IS5220A (is) 1999-10-19
WO1998050033A1 (en) 1998-11-12
YU55899A (sh) 2003-08-29
TNSN98059A1 (fr) 2005-03-15
AR011726A1 (es) 2000-08-30
ZA983722B (en) 1999-11-04
EA003696B1 (ru) 2003-08-28
TW590773B (en) 2004-06-11
HUP0001286A3 (en) 2000-12-28
NO995389D0 (no) 1999-11-04
PE72599A1 (es) 1999-08-12
UY24989A1 (es) 2001-10-25
IL132570A0 (en) 2001-03-19
AU6932198A (en) 1998-11-27
PA8450601A1 (es) 2000-05-24
AP9801234A0 (en) 1999-11-04
JP2000513020A (ja) 2000-10-03
EP0988034A1 (en) 2000-03-29

Similar Documents

Publication Publication Date Title
KR20040004406A (ko) 개의 통증 및 염증을 치료하기 위한사이클로-옥시게나제-2 선택적 억제 화합물
US20060217431A1 (en) Composition comprising a combined thromboxane receptor antagonist and thromboxane synthase inhibitor and a COX-2 inhibitor
AU2015314772B2 (en) Compositions and methods for treatment of prostate carcinoma
JP2002526408A (ja) 疼痛および不安の処置のためのmglur5アンタゴニスト
KR20220140027A (ko) 신경교종을 포함하는 암을 치료하기 위해 에플로르니틴 및 이의 유도체 및 동족체를 사용하기 위한 조성물 및 방법
EP2776031A1 (en) N-methyl-2-[3-((e)-2-pyridin-2-yl-vinyl)-1h-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemia
EP1259234A1 (en) 3-heteroarylidenyl-2-indolinone compounds for modulating protein kinase activity and for use in cancer chemotherapy
US20030212123A1 (en) COX-2 selective carprofen for treating pain and inflammation in dogs
JP2001514655A (ja) アルツハイマー病予防へのr−nsaid’sの利用
TW200817401A (en) KW-3902 conjugates that do not cross the blood-brain barrier
US20040266834A1 (en) Thiazolidinediones alone or in cabination with other therapeutic agents for cancer therapy
Quintás-Cardama et al. Practical management of toxicities associated with tyrosine kinase inhibitors in chronic myeloid leukemia
JP2000086629A (ja) 新規な酸化窒素放出化合物
AU773615B2 (en) COX-2 selective carprofen for treating pain and inflammation in dogs
Black Selective cyclooxygenase-2 inhibitors
CZ9903896A3 (cs) Léčivo, farmaceutický přípravek a souprava pro léčení nebo prevenci bolesti a zánětlivých procesů
US20150065486A1 (en) Methods for treating polycystic kidney disease
NZ516914A (en) Compositions containing COX-2 selective carprofen and derivatives thereof for treating pain and inflammation in dogs
JP2016504994A (ja) 糖尿病患者における心血管リスクの治療
JP2005525999A (ja) 原発性脳腫瘍または転移性脳腫瘍を治療または予防するためのベンゾピラノン誘導体の使用
JP2007504164A (ja) PPAR−γ経路およびHER−キナーゼ軸の調節に基づく癌および他の生理学的状態の処置のための組成物および方法
US9962378B2 (en) ROS1 inhibitor and its use
FR2565588A1 (fr) Produits pharmaceutiques cardio-actifs, en particulier anti-arythmiques, a base de composes triaminoarylpteridiniques
US8933037B2 (en) Methods involving PDGFRBETA inhibitors
JPH09165338A (ja) 梗塞サイズ減少剤

Legal Events

Date Code Title Description
A107 Divisional application of patent
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application