UY24989A1 - Carprofeno, un inhibidor de cox-2, útil en el tratamiento del dolor e inflamación en perros - Google Patents

Carprofeno, un inhibidor de cox-2, útil en el tratamiento del dolor e inflamación en perros

Info

Publication number
UY24989A1
UY24989A1 UY24989A UY24989A UY24989A1 UY 24989 A1 UY24989 A1 UY 24989A1 UY 24989 A UY24989 A UY 24989A UY 24989 A UY24989 A UY 24989A UY 24989 A1 UY24989 A1 UY 24989A1
Authority
UY
Uruguay
Prior art keywords
cox
inhibitor
activity
dogs
carprophen
Prior art date
Application number
UY24989A
Other languages
English (en)
Inventor
Ricketts Anthony Paul
Lundy Kristin Marie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY24989A1 publication Critical patent/UY24989A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Tratamiento o prevención de procesos y enfermedades inflamatorias en perros asociadas con la actividad de la ciclo-oxigenasa-2 (COX-2) inducible, mientras que al mismo tiempo se reducen o eliminan los efectos secundarios indeseables asociados con la inhibición simultánea de la actividad de la ciclo-oxigenasa-1 (COX-1) constitutiva, mediante la inhibición selectiva de la actividad de COX-2 con respecto a la actividad de la COX-1, donde la relación de selectividad de COX-2:COX-1 es de al menos 3:1 basándose en los niveles de inhibición ex vivo medidos en sangre entera; el inhibidor es un miembro seleccionado entre el grupo de AINEs (anti-inflamatorios no esteroideos). En particular, el inhibidor de COX-2 que se reinvidica es el carprofeno [(+)-(S) ácido 6-cloro-alfa-metil-9H-carbazol-2-acético].
UY24989A 1997-05-05 1998-05-04 Carprofeno, un inhibidor de cox-2, útil en el tratamiento del dolor e inflamación en perros UY24989A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4563597P 1997-05-05 1997-05-05

Publications (1)

Publication Number Publication Date
UY24989A1 true UY24989A1 (es) 2001-10-25

Family

ID=21939053

Family Applications (1)

Application Number Title Priority Date Filing Date
UY24989A UY24989A1 (es) 1997-05-05 1998-05-04 Carprofeno, un inhibidor de cox-2, útil en el tratamiento del dolor e inflamación en perros

Country Status (32)

Country Link
EP (1) EP0988034A1 (es)
JP (1) JP2000513020A (es)
KR (2) KR20040004406A (es)
CN (1) CN1255059A (es)
AP (1) AP9801234A0 (es)
AR (2) AR011726A1 (es)
AU (1) AU6932198A (es)
BG (1) BG103852A (es)
BR (1) BR9808720A (es)
CA (1) CA2288759A1 (es)
DZ (1) DZ2479A1 (es)
EA (1) EA003696B1 (es)
GT (1) GT199800063A (es)
HR (1) HRP980244A2 (es)
HU (1) HUP0001286A3 (es)
ID (1) ID21311A (es)
IL (1) IL132570A0 (es)
IS (1) IS5220A (es)
MA (1) MA26491A1 (es)
NO (1) NO995389L (es)
NZ (1) NZ500183A (es)
OA (1) OA11213A (es)
PA (1) PA8450601A1 (es)
PE (1) PE72599A1 (es)
PL (1) PL337003A1 (es)
SK (1) SK148199A3 (es)
TN (1) TNSN98059A1 (es)
TW (1) TW590773B (es)
UY (1) UY24989A1 (es)
WO (1) WO1998050033A1 (es)
YU (1) YU55899A (es)
ZA (1) ZA983722B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245797B1 (en) 1997-10-22 2001-06-12 Merck & Co., Inc. Combination therapy for reducing the risks associated with cardio-and-cerebrovascular disease
US6506785B2 (en) 1998-05-22 2003-01-14 Pfizer, Inc. Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives
AU2003204888B2 (en) * 1998-05-22 2005-07-28 Pfizer Products Inc. Treating or Preventing the Early Stages of Degeneration of Articular Cartilage or Subchondral Bone in Mammals Using Carprofen and Derivatives
CA2347365A1 (en) * 1998-10-23 2000-05-04 Merck Frosst Canada & Co. Combination product comprising an e-type prostaglandin ligand and a cox-2 selective inhibitor and methods of use
EP1637137A3 (en) * 1999-03-10 2006-07-05 G.D. Searle LLC Method and composition for administering a cyclooxygenase-2 inhibitor to animals
AU1592901A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
JP2004521856A (ja) * 2000-05-15 2004-07-22 メルク フロスト カナダ アンド カンパニー Ｃｏｘ−２選択的阻害剤およびトロンボキサン阻害剤を用いる併用療法ならびにそのための組成物
AU6837701A (en) 2000-06-13 2001-12-24 American Home Prod Analgesic and anti-inflammatory compositions containing cox-2 inhibitors
DE10032132A1 (de) * 2000-07-01 2002-01-17 Lohmann Therapie Syst Lts Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung
US20020106707A1 (en) 2000-08-07 2002-08-08 Marnett Lawrence J. Compositions and methods for detecting and quantifying COX-2 activity and anandamide metabolites
US20040209959A1 (en) * 2001-07-16 2004-10-21 Edward Hogestatt Congeners of acetaminophen and related compounds as substrates for fatty acid conjugation and their use in treatment of pain, fever and inflammation
PT1534305E (pt) 2003-05-07 2007-02-28 Osteologix As Tratamento de afecções cartilagineas / osseas com sais de estroncio hidrosoluveis
WO2005009436A1 (en) * 2003-07-31 2005-02-03 Pharmacia & Upjohn Company Llc Dispersible formulation of an anti-inflammatory agent
EP1940380A2 (en) * 2005-05-20 2008-07-09 Pfizer Limited Synergistic combinations of non-steroidal antiinflammatory drugs with alpha-2 delta-ligands
US8535713B2 (en) 2007-04-04 2013-09-17 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
US8951570B2 (en) 2007-04-26 2015-02-10 Sigmoid Pharma Limited Manufacture of multiple minicapsules
JP5640079B2 (ja) 2009-05-18 2014-12-10 シグモイド・ファーマ・リミテッドＳｉｇｍｏｉｄ Ｐｈａｒｍａ Ｌｉｍｉｔｅｄ 油滴含有組成物
BR112012002963A2 (pt) 2009-08-12 2017-10-24 Sigmoid Pharma Ltd composições imunomoduladoras compreendendo uma matriz de polímero e uma fase oleosa
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
CA2941008C (en) 2014-03-06 2022-07-26 Aratana Therapeutics, Inc. Compositions of grapiprant and methods for using the same
EP3215127B1 (en) 2014-11-07 2020-10-28 Sublimity Therapeutics Limited Compositions comprising cyclosporin
BR112017014750A2 (pt) * 2015-01-09 2018-06-19 Jaguar Animal Health métodos para tratamento de diarreia em animais de estimação
CN115335046A (zh) * 2020-03-25 2022-11-11 思研（Sri）国际顾问与咨询公司 脂肪氧合酶抑制剂
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections
KR102404883B1 (ko) 2020-11-30 2022-06-07 (주)이노보테라퓨틱스 벤즈브로마론을 포함하는 켈로이드 또는 비대흉터 예방 또는 치료용 약학 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896145A (en) * 1972-07-24 1975-07-22 Hoffmann La Roche Carbazoles
CA1319886C (en) * 1987-02-03 1993-07-06 Alberto Ferro Mixed micelle solutions

Also Published As

Publication number Publication date
WO1998050033A1 (en) 1998-11-12
HUP0001286A3 (en) 2000-12-28
AP9801234A0 (en) 1999-11-04
HUP0001286A2 (hu) 2000-11-28
KR20010012300A (ko) 2001-02-15
DZ2479A1 (fr) 2003-02-01
PA8450601A1 (es) 2000-05-24
MA26491A1 (fr) 2004-12-20
JP2000513020A (ja) 2000-10-03
EA003696B1 (ru) 2003-08-28
BR9808720A (pt) 2000-07-11
EP0988034A1 (en) 2000-03-29
HRP980244A2 (en) 1999-02-28
TNSN98059A1 (fr) 2005-03-15
PE72599A1 (es) 1999-08-12
SK148199A3 (en) 2001-09-11
BG103852A (en) 2000-06-30
CN1255059A (zh) 2000-05-31
AU6932198A (en) 1998-11-27
AR011726A1 (es) 2000-08-30
ZA983722B (en) 1999-11-04
ID21311A (id) 1999-05-20
PL337003A1 (en) 2000-07-31
GT199800063A (es) 1999-10-26
NO995389L (no) 2000-01-04
NZ500183A (en) 2002-04-26
OA11213A (en) 2003-07-14
EA199900895A1 (ru) 2000-06-26
NO995389D0 (no) 1999-11-04
CA2288759A1 (en) 1998-11-12
IS5220A (is) 1999-10-19
AR039628A2 (es) 2005-03-02
YU55899A (sh) 2003-08-29
KR20040004406A (ko) 2004-01-13
TW590773B (en) 2004-06-11
IL132570A0 (en) 2001-03-19

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