KR20030062944A - 치아의 재석회화 촉진제 - Google Patents
치아의 재석회화 촉진제 Download PDFInfo
- Publication number
- KR20030062944A KR20030062944A KR1020020003414A KR20020003414A KR20030062944A KR 20030062944 A KR20030062944 A KR 20030062944A KR 1020020003414 A KR1020020003414 A KR 1020020003414A KR 20020003414 A KR20020003414 A KR 20020003414A KR 20030062944 A KR20030062944 A KR 20030062944A
- Authority
- KR
- South Korea
- Prior art keywords
- tooth
- weight
- remineralization
- enamel
- composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 40
- 230000001737 promoting effect Effects 0.000 title description 4
- 210000003298 dental enamel Anatomy 0.000 claims abstract description 39
- 241001474374 Blennius Species 0.000 claims abstract description 33
- 229940112822 chewing gum Drugs 0.000 claims abstract description 33
- 235000015218 chewing gum Nutrition 0.000 claims abstract description 33
- 208000002925 dental caries Diseases 0.000 claims abstract description 28
- 239000000284 extract Substances 0.000 claims abstract description 25
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 18
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000000811 xylitol Substances 0.000 claims abstract description 18
- 235000010447 xylitol Nutrition 0.000 claims abstract description 18
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 18
- 229960002675 xylitol Drugs 0.000 claims abstract description 18
- 150000005846 sugar alcohols Chemical class 0.000 claims abstract description 16
- 102000014171 Milk Proteins Human genes 0.000 claims abstract description 11
- 108010011756 Milk Proteins Proteins 0.000 claims abstract description 11
- 235000021239 milk protein Nutrition 0.000 claims abstract description 11
- 239000005018 casein Substances 0.000 claims abstract description 9
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical group NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000021240 caseins Nutrition 0.000 claims abstract description 9
- 239000003531 protein hydrolysate Substances 0.000 claims abstract description 8
- 230000002265 prevention Effects 0.000 claims abstract description 6
- 108010001441 Phosphopeptides Proteins 0.000 claims abstract description 5
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 claims abstract description 4
- 239000000905 isomalt Substances 0.000 claims abstract description 4
- 235000010439 isomalt Nutrition 0.000 claims abstract description 4
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000000845 maltitol Substances 0.000 claims abstract description 4
- 235000010449 maltitol Nutrition 0.000 claims abstract description 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims abstract description 3
- 239000004386 Erythritol Substances 0.000 claims abstract description 3
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims abstract description 3
- 229930195725 Mannitol Natural products 0.000 claims abstract description 3
- 235000019414 erythritol Nutrition 0.000 claims abstract description 3
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims abstract description 3
- 229940009714 erythritol Drugs 0.000 claims abstract description 3
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims abstract description 3
- 229940035436 maltitol Drugs 0.000 claims abstract description 3
- 239000000594 mannitol Substances 0.000 claims abstract description 3
- 235000010355 mannitol Nutrition 0.000 claims abstract description 3
- 229960001855 mannitol Drugs 0.000 claims abstract description 3
- 239000000600 sorbitol Substances 0.000 claims abstract description 3
- 235000010356 sorbitol Nutrition 0.000 claims abstract description 3
- 229960002920 sorbitol Drugs 0.000 claims abstract description 3
- 239000001506 calcium phosphate Substances 0.000 claims description 28
- 235000019739 Dicalciumphosphate Nutrition 0.000 claims description 18
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 claims description 18
- 229910000390 dicalcium phosphate Inorganic materials 0.000 claims description 18
- 229940038472 dicalcium phosphate Drugs 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 9
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 9
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 7
- 235000011010 calcium phosphates Nutrition 0.000 claims description 7
- 241000195493 Cryptophyta Species 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- 241000206753 Gloiopeltis Species 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 230000003449 preventive effect Effects 0.000 claims description 2
- 230000002797 proteolythic effect Effects 0.000 claims description 2
- 238000010422 painting Methods 0.000 claims 1
- 239000011575 calcium Substances 0.000 abstract description 34
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 31
- 229910052791 calcium Inorganic materials 0.000 abstract description 31
- 235000019700 dicalcium phosphate Nutrition 0.000 abstract description 8
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 abstract description 7
- 229940095079 dicalcium phosphate anhydrous Drugs 0.000 abstract description 5
- 238000010521 absorption reaction Methods 0.000 abstract description 4
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 241000142861 Gloiopeltis furcata Species 0.000 abstract 2
- 241000206752 Gloiopeltis complanata Species 0.000 abstract 1
- 241000691324 Gloiopeltis tenax Species 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 19
- 230000000694 effects Effects 0.000 description 15
- 230000001055 chewing effect Effects 0.000 description 8
- 235000013305 food Nutrition 0.000 description 8
- 239000013078 crystal Substances 0.000 description 6
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 6
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 210000000214 mouth Anatomy 0.000 description 5
- -1 sodium monofluorine (monofluorine) Chemical compound 0.000 description 5
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 210000003296 saliva Anatomy 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 238000005115 demineralization Methods 0.000 description 3
- 230000002328 demineralizing effect Effects 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 238000001878 scanning electron micrograph Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 3
- 235000019731 tricalcium phosphate Nutrition 0.000 description 3
- 229940078499 tricalcium phosphate Drugs 0.000 description 3
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 2
- 108010001682 Dextranase Proteins 0.000 description 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 2
- 229920001503 Glucan Polymers 0.000 description 2
- 102000000340 Glucosyltransferases Human genes 0.000 description 2
- 108010055629 Glucosyltransferases Proteins 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 241000194019 Streptococcus mutans Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 235000019658 bitter taste Nutrition 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000002532 enzyme inhibitor Substances 0.000 description 2
- 235000013373 food additive Nutrition 0.000 description 2
- 239000002778 food additive Substances 0.000 description 2
- 235000003599 food sweetener Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 235000015243 ice cream Nutrition 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 235000013622 meat product Nutrition 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000003765 sweetening agent Substances 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- BZQFBWGGLXLEPQ-UHFFFAOYSA-N O-phosphoryl-L-serine Natural products OC(=O)C(N)COP(O)(O)=O BZQFBWGGLXLEPQ-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Natural products P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 description 1
- 241001674048 Phthiraptera Species 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000193987 Streptococcus sobrinus Species 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 235000015895 biscuits Nutrition 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 150000001669 calcium Chemical class 0.000 description 1
- XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 201000001883 cholelithiasis Diseases 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001218 confocal laser scanning microscopy Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- RKTYLMNFRDHKIL-UHFFFAOYSA-N copper;5,10,15,20-tetraphenylporphyrin-22,24-diide Chemical compound [Cu+2].C1=CC(C(=C2C=CC([N-]2)=C(C=2C=CC=CC=2)C=2C=CC(N=2)=C(C=2C=CC=CC=2)C2=CC=C3[N-]2)C=2C=CC=CC=2)=NC1=C3C1=CC=CC=C1 RKTYLMNFRDHKIL-UHFFFAOYSA-N 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000037123 dental health Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 235000011850 desserts Nutrition 0.000 description 1
- 229950006137 dexfosfoserine Drugs 0.000 description 1
- 150000004683 dihydrates Chemical class 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 201000010840 enamel caries Diseases 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000010794 food waste Substances 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 208000001130 gallstones Diseases 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 235000021384 green leafy vegetables Nutrition 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 210000004373 mandible Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000012149 noodles Nutrition 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 210000004798 organs belonging to the digestive system Anatomy 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 description 1
- BZQFBWGGLXLEPQ-REOHCLBHSA-N phosphoserine Chemical compound OC(=O)[C@@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-REOHCLBHSA-N 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 235000012045 salad Nutrition 0.000 description 1
- 235000013580 sausages Nutrition 0.000 description 1
- 238000004626 scanning electron microscopy Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229910010271 silicon carbide Inorganic materials 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 239000011775 sodium fluoride Substances 0.000 description 1
- 235000013024 sodium fluoride Nutrition 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 235000013555 soy sauce Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 description 1
- 229960002799 stannous fluoride Drugs 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000008379 tooth decay inhibitor Substances 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/064—Chewing gum characterised by the composition containing organic or inorganic compounds containing inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/068—Chewing gum characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/14—Chewing gum characterised by the composition containing organic or inorganic compounds containing peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/312—Foods, ingredients or supplements having a functional effect on health having an effect on dental health
Abstract
Description
구성성분(단위:중량%) | 실시예 1 | 실시예 2 | 비교예 1 | 비교예 2 | 비교예 3 |
껌베이스 | 25 | 25 | 25 | 25 | 25 |
자일리톨 | 41 | 41 | 41 | 41 | 41 |
이소말트 | 25 | 25 | 25 | 25 | 25 |
말티톨시럽 | 5.6 | 5.6 | 5.6 | 5.6 | 5.6 |
감미개선제 | 0.14 | 0.12 | 0.6 | 0.34 | 0.22 |
향료 | 1.8 | 1.8 | 1.8 | 1.8 | 1.8 |
글리세린 | 1 | 1 | 1 | 1 | 1 |
제2인산칼슘 | 0.26(0.06)* | 0.26(0.06)* | - | 0.26(0.06)* | 0.26(0.06)* |
후노란 | - | 0.12 | - | - | 0.12 |
CPP제제 | 0.08(0.02)** | 0.08(0.02)** | - | - | - |
계 | 100 | 100 | 100 | 100 | 100 |
*)칼슘으로서의 함량**)순수CPP로서의 함량 |
실시예 1 | 실시예 2 | 비교예 1 | 비교예 2 | 비교예 3 | |
치아표면의 평균경도(g/㎟) | 110∼130 | 165∼200 | 23∼50 | 51∼65 | 75∼83 |
치아표면의 광질변화*(㎛) | 90∼120 | 140∼165 | 10∼20 | 30∼50 | 70∼90 |
*재석회화의 평균깊이. |
실시예 1 | 실시예 2 | 비교예 1 | 비교예 2 | 비교예 3 | |
많이 개선 | 13 | 17 | 3 | 6 | 9 |
약간 개선 | 4 | 2 | 10 | 9 | 7 |
차이 없음 | 2 | 1 | 5 | 6 | 2 |
더 나빠짐 | 1 | - | 2 | 2 | 2 |
계(명) | 20 | 20 | 20 | 20 | 20 |
입안이 개운해지고 이가 시린 증상의 개선정도 |
Claims (6)
- 당알콜, 제2인산칼슘, 해조류 또는 해조추출물이 유효성분으로 함유된 치아에나멜질의 재석회화 촉진제가 함유된 조성물에 있어서,당알콜 1.0 ∼ 99.0 중량%, 제2인산칼슘 0.01 ∼ 10.0 중량%, 해조류, 해조추출물 또는 이들의 혼합물 0.01 ∼ 5.0 중량% 및 유단백가수분해물 0.005 ∼ 0.5 중량% 가 포함된 것임을 특징으로 하는 치아에나멜질의 재석회화 및 치아우식 예방 조성물.
- 제 1 항에 있어서, 상기 당알콜은 자일리톨, 소르비톨, 만니톨, 말티톨, 에리쓰리톨 및 이소말트 중에서 선택된 것임을 특징으로 하는 치아에나멜질의 재석회화 및 치아우식 예방 조성물.
- 제 1 항 또는 제 2 항에 있어서, 상기 당알콜은 자일리톨인 것임을 특징으로 하는 치아에나멜질의 재석회화 및 치아우식 예방 조성물.
- 제 1 항에 있어서, 상기 해조류, 해조추출물 또는 이들의 혼합물은 카쿠레이트목(Cryptonemiales) 청각채과(Endocladiaceae) 청각채속(Gloiopeltis)에 속하는 청각채를 사용한 것임을 특징으로 하는 치아에나멜질의 재석회화 및 치아우식 예방 조성물.
- 제 1 항에 있어서, 상기 유단백분해물질은 카제인포스포펩티드(Casein Phospho Peptide)인 것임을 특징으로 하는 치아에나멜질의 재석회화 및 치아우식 예방 조성물.
- 통상의 츄잉껌 조성물에 있어서, 상기 청구항 1 의 치아에나멜질의 재석회화 촉진제가 함유된 것임을 특징으로 하는 츄잉껌 조성물.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2002-0003414A KR100445994B1 (ko) | 2002-01-21 | 2002-01-21 | 치아의 재석회화 촉진제 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2002-0003414A KR100445994B1 (ko) | 2002-01-21 | 2002-01-21 | 치아의 재석회화 촉진제 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20030062944A true KR20030062944A (ko) | 2003-07-28 |
KR100445994B1 KR100445994B1 (ko) | 2004-08-25 |
Family
ID=32218758
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR10-2002-0003414A KR100445994B1 (ko) | 2002-01-21 | 2002-01-21 | 치아의 재석회화 촉진제 |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR100445994B1 (ko) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100963619B1 (ko) * | 2006-11-18 | 2010-06-15 | 롯데제과주식회사 | 치질 강화제, 이를 함유하는 구강용 조성물과 음식물 및 이들의 제조방법 |
KR101154932B1 (ko) * | 2005-01-10 | 2012-06-13 | 주식회사 엘지생활건강 | 안전성이 강화된 치아미백용 패취 |
TWI399217B (zh) * | 2004-12-21 | 2013-06-21 | Colgate Palmolive Co | 含木糖醇之抗齲齒口腔護理組合物 |
CN111249178A (zh) * | 2020-03-20 | 2020-06-09 | 成都爱睿康乐医疗器械有限公司 | 一种儿童防龋牙膏 |
CN111297738A (zh) * | 2020-04-24 | 2020-06-19 | 山东大学 | 一种海藻面膜及其制备方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5227154A (en) * | 1991-08-22 | 1993-07-13 | The University Of Melbourne | Phosphopeptides for the treatment of dental calculus |
DE69327845T2 (de) * | 1992-06-29 | 2000-10-26 | Univ Melbourne Parkville | Behandlung von empfindlichen zähnen |
KR100343542B1 (ko) * | 1996-09-12 | 2002-11-07 | 롯데제과주식회사 | 츄잉껌 조성물 |
JP4082782B2 (ja) * | 1998-04-30 | 2008-04-30 | 雪印乳業株式会社 | 歯周病予防及び改善剤 |
JP3689802B2 (ja) * | 1998-08-06 | 2005-08-31 | 株式会社ロッテ | 歯牙エナメル質の再石灰化促進剤及び口腔用組成物並びに飲食物 |
JP3689803B2 (ja) * | 1998-10-20 | 2005-08-31 | 株式会社ロッテ | 歯牙エナメル質の再石灰化促進剤及び口腔用組成物並びに飲食物 |
KR100999999B1 (ko) * | 2008-01-18 | 2010-12-10 | 주식회사 다이아벨 | 슬라이딩 장치 |
-
2002
- 2002-01-21 KR KR10-2002-0003414A patent/KR100445994B1/ko active IP Right Grant
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI399217B (zh) * | 2004-12-21 | 2013-06-21 | Colgate Palmolive Co | 含木糖醇之抗齲齒口腔護理組合物 |
US8858920B2 (en) | 2004-12-21 | 2014-10-14 | Colgate-Palmolive Company | Anti-caries oral care composition with xylitol |
KR101154932B1 (ko) * | 2005-01-10 | 2012-06-13 | 주식회사 엘지생활건강 | 안전성이 강화된 치아미백용 패취 |
KR100963619B1 (ko) * | 2006-11-18 | 2010-06-15 | 롯데제과주식회사 | 치질 강화제, 이를 함유하는 구강용 조성물과 음식물 및 이들의 제조방법 |
CN111249178A (zh) * | 2020-03-20 | 2020-06-09 | 成都爱睿康乐医疗器械有限公司 | 一种儿童防龋牙膏 |
CN111297738A (zh) * | 2020-04-24 | 2020-06-19 | 山东大学 | 一种海藻面膜及其制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
KR100445994B1 (ko) | 2004-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6733818B2 (en) | Oral care confections and method of using | |
US4908211A (en) | Chewing gum and ingredients to chemically inhibit formation of plaque and calculus | |
JP5726533B2 (ja) | リン酸化糖、ポリフェノールおよびフッ素を含む、食品および組成物 | |
JP3648587B2 (ja) | 歯周病予防又は歯周病進行予防食品組成物 | |
BRPI0618143A2 (pt) | uso de sais de cálcio dificilmente hidrossolúveis e/ou seus compósitos | |
EP1176939B1 (en) | Oral care chewing gums and confections | |
JP3689803B2 (ja) | 歯牙エナメル質の再石灰化促進剤及び口腔用組成物並びに飲食物 | |
JP3689802B2 (ja) | 歯牙エナメル質の再石灰化促進剤及び口腔用組成物並びに飲食物 | |
CN101330943A (zh) | 表面活性钙磷酸盐 | |
EP1010430B1 (en) | Preventives and ameliorating agents for periodontosis | |
JP3396009B2 (ja) | 低う蝕性栄養組成物 | |
US20170216167A1 (en) | Acidic solid oral compositions without erosive potential in saliva and method for determining erosive potential in saliva | |
KR100445994B1 (ko) | 치아의 재석회화 촉진제 | |
JP3650705B2 (ja) | パラチニット含有食品 | |
JP5977835B2 (ja) | 象牙細管封鎖剤 | |
JP2002325556A (ja) | リン酸化オリゴ糖を含有する抗う蝕機能を有する組成物 | |
KR100379641B1 (ko) | 구강 위생용 조성물 및 음식물 | |
KR0179523B1 (ko) | 치은염 치료용 유향과 창출 추출물 함유 치약조성물 | |
JPH0699294B2 (ja) | 歯石防止組成物 | |
JP2015127310A (ja) | 口腔用組成物 | |
JP2002121146A (ja) | 歯周病予防用製剤 | |
MXPA01007713A (en) | Oral care chewing gums and confections | |
UA70276C2 (uk) | Жувальна гумка | |
MXPA99001686A (en) | Anti-carious chewing gums, candies, gels, toothpastes and dentifrices |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20130116 Year of fee payment: 10 |
|
FPAY | Annual fee payment |
Payment date: 20140114 Year of fee payment: 11 |
|
FPAY | Annual fee payment |
Payment date: 20150126 Year of fee payment: 12 |
|
FPAY | Annual fee payment |
Payment date: 20160125 Year of fee payment: 13 |
|
FPAY | Annual fee payment |
Payment date: 20170113 Year of fee payment: 14 |
|
FPAY | Annual fee payment |
Payment date: 20180123 Year of fee payment: 15 |