KR20030005190A - 카르복사미딘-개질된 바이시클릭 염기를 지닌뉴클레오시드 유사체 - Google Patents

카르복사미딘-개질된 바이시클릭 염기를 지닌뉴클레오시드 유사체 Download PDF

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Publication number
KR20030005190A
KR20030005190A KR1020027010593A KR20027010593A KR20030005190A KR 20030005190 A KR20030005190 A KR 20030005190A KR 1020027010593 A KR1020027010593 A KR 1020027010593A KR 20027010593 A KR20027010593 A KR 20027010593A KR 20030005190 A KR20030005190 A KR 20030005190A
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South Korea
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cells
type
cytokine
icn
compounds
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English (en)
Korean (ko)
Inventor
로버트 탐
구안기 왕
지 홍
존슨 라우
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아이씨엔 파마슈티컬스, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
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    • A61P31/14—Antivirals for RNA viruses
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
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  • Communicable Diseases (AREA)
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  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
KR1020027010593A 2000-02-15 2001-02-15 카르복사미딘-개질된 바이시클릭 염기를 지닌뉴클레오시드 유사체 Withdrawn KR20030005190A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18267600P 2000-02-15 2000-02-15
US60/182,676 2000-02-15
US09/595,365 2000-06-16
US09/595,365 US6455508B1 (en) 2000-02-15 2000-10-05 Methods for treating diseases with tirazole and pyrrolo-pyrimidine ribofuranosyl nucleosides

Publications (1)

Publication Number Publication Date
KR20030005190A true KR20030005190A (ko) 2003-01-17

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ID=26878297

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Application Number Title Priority Date Filing Date
KR1020027010593A Withdrawn KR20030005190A (ko) 2000-02-15 2001-02-15 카르복사미딘-개질된 바이시클릭 염기를 지닌뉴클레오시드 유사체
KR1020027010417A Expired - Fee Related KR100811927B1 (ko) 2000-02-15 2001-02-15 카복사미딘 변형된 모노사이클릭 염기를 함유하는누클레오시드 유사체

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KR1020027010417A Expired - Fee Related KR100811927B1 (ko) 2000-02-15 2001-02-15 카복사미딘 변형된 모노사이클릭 염기를 함유하는누클레오시드 유사체

Country Status (28)

Country Link
US (1) US6455508B1 (enExample)
EP (3) EP1813278B9 (enExample)
JP (3) JP4975930B2 (enExample)
KR (2) KR20030005190A (enExample)
CN (2) CN1268335C (enExample)
AT (1) ATE377422T1 (enExample)
AU (2) AU3845001A (enExample)
BR (2) BR0108402A (enExample)
CA (2) CA2395854A1 (enExample)
CY (1) CY1107103T1 (enExample)
CZ (2) CZ302327B6 (enExample)
DE (1) DE60131250T8 (enExample)
DK (1) DK1257281T3 (enExample)
ES (2) ES2295148T3 (enExample)
HR (2) HRP20020657A2 (enExample)
HU (2) HUP0300912A2 (enExample)
IL (3) IL150555A0 (enExample)
MX (2) MXPA02007931A (enExample)
NO (2) NO329927B1 (enExample)
NZ (2) NZ521390A (enExample)
PL (2) PL200140B1 (enExample)
PT (1) PT1257281E (enExample)
RS (1) RS20090086A (enExample)
RU (2) RU2002120483A (enExample)
SI (2) SI21076A (enExample)
SK (2) SK11572002A3 (enExample)
WO (2) WO2001060381A1 (enExample)
YU (1) YU61502A (enExample)

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