KR20020022045A - 유게놀 및 페룰라산 분해대사의 유전자를 특이적으로불활성화함으로써 치환된 페놀을 생성하기 위한 생산균주의 구축 - Google Patents

유게놀 및 페룰라산 분해대사의 유전자를 특이적으로불활성화함으로써 치환된 페놀을 생성하기 위한 생산균주의 구축 Download PDF

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Publication number
KR20020022045A
KR20020022045A KR1020017005493A KR20017005493A KR20020022045A KR 20020022045 A KR20020022045 A KR 20020022045A KR 1020017005493 A KR1020017005493 A KR 1020017005493A KR 20017005493 A KR20017005493 A KR 20017005493A KR 20020022045 A KR20020022045 A KR 20020022045A
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KR
South Korea
Prior art keywords
gene
vanillin
inactivated
eugenol
dehydrogenase
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KR1020017005493A
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English (en)
Korean (ko)
Inventor
위르겐 라벤호르스트
알렉산더 슈타인뷔헬
호르스트 프리페르트
외르크 오베르하게
Original Assignee
요헨 슈레
하르만 운트 라이머 게엠베하
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Publication of KR20020022045A publication Critical patent/KR20020022045A/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01016Acetyl-CoA C-acyltransferase (2.3.1.16)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020017005493A 1998-10-31 1999-10-20 유게놀 및 페룰라산 분해대사의 유전자를 특이적으로불활성화함으로써 치환된 페놀을 생성하기 위한 생산균주의 구축 KR20020022045A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19850242A DE19850242A1 (de) 1998-10-31 1998-10-31 Konstruktion von Produktionsstämmen für die Herstellung von substituierten Phenolen durch gezielte Inaktivierung von Genen des Eugenol- und Ferulasäure-Katabolismus
DE19850242.7 1998-10-31
PCT/EP1999/007952 WO2000026355A2 (de) 1998-10-31 1999-10-20 Konstruktion von produktionsstämmen für die herstellung von substituierten phenolen durch gezielte inaktivierungen von genen des eugenol- und ferulasäure-katabolismus

Publications (1)

Publication Number Publication Date
KR20020022045A true KR20020022045A (ko) 2002-03-23

Family

ID=7886266

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017005493A KR20020022045A (ko) 1998-10-31 1999-10-20 유게놀 및 페룰라산 분해대사의 유전자를 특이적으로불활성화함으로써 치환된 페놀을 생성하기 위한 생산균주의 구축

Country Status (14)

Country Link
EP (1) EP1124947A2 (de)
JP (1) JP2003533166A (de)
KR (1) KR20020022045A (de)
CN (1) CN1325444A (de)
AU (1) AU761093B2 (de)
BR (1) BR9914930A (de)
CA (1) CA2348962A1 (de)
DE (1) DE19850242A1 (de)
HK (1) HK1041902A1 (de)
HU (1) HUP0104772A3 (de)
IL (1) IL142272A0 (de)
PL (1) PL348647A1 (de)
SK (1) SK5742001A3 (de)
WO (1) WO2000026355A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100830691B1 (ko) * 2006-11-21 2008-05-20 광주과학기술원 이소유제놀과 유제놀로부터 천연바닐린과 바닐린 산으로 생전환하는 신규 미생물

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2721148B1 (de) 2011-06-17 2018-09-12 Symrise AG Mikroorganismen und verfahren zur herstellung substituierter phenole
JP6509215B2 (ja) 2013-07-22 2019-05-08 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se フェルラ酸からのバニリンの迅速かつ高収率な製造のためのシュードモナス・プチダkt2440の遺伝子操作
CN103805640B (zh) * 2014-01-26 2016-04-06 东华大学 一种利用细菌氧化松伯醛制备阿魏酸的方法
EP3000888B1 (de) * 2014-09-29 2018-12-05 Symrise AG Verfahren zur Umwandlung von Ferulasäure in Vanillin
FR3041655B1 (fr) * 2015-09-29 2017-11-24 Lesaffre & Cie Nouvelles souches bacteriennes pour la production de vanilline
CN111019995B (zh) 2019-12-31 2021-04-27 厦门欧米克生物科技有限公司 一种以丁香酚为底物发酵生成香兰素的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05227980A (ja) * 1992-02-21 1993-09-07 Takasago Internatl Corp 発酵法によるバニリンおよびその関連化合物の製造法
DE4227076A1 (de) * 1992-08-17 1994-02-24 Haarmann & Reimer Gmbh Verfahren zur Herstellung substituierter Methoxyphenole und dafür geeignete Mikroorganismen
GB9606187D0 (en) * 1996-03-23 1996-05-29 Inst Of Food Research Production of vanillin
DE19649655A1 (de) * 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100830691B1 (ko) * 2006-11-21 2008-05-20 광주과학기술원 이소유제놀과 유제놀로부터 천연바닐린과 바닐린 산으로 생전환하는 신규 미생물

Also Published As

Publication number Publication date
EP1124947A2 (de) 2001-08-22
HUP0104772A3 (en) 2003-10-28
DE19850242A1 (de) 2000-05-04
BR9914930A (pt) 2001-07-10
AU761093B2 (en) 2003-05-29
JP2003533166A (ja) 2003-11-11
CA2348962A1 (en) 2000-05-11
SK5742001A3 (en) 2001-12-03
HUP0104772A2 (hu) 2002-03-28
WO2000026355A2 (de) 2000-05-11
CN1325444A (zh) 2001-12-05
HK1041902A1 (zh) 2002-07-26
IL142272A0 (en) 2002-03-10
PL348647A1 (en) 2002-06-03
WO2000026355A3 (de) 2000-11-09
AU1041300A (en) 2000-05-22

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