CA2348962A1 - Construction of production strains for producing substituted phenols by specifically inactivating genes of the eugenol and ferulic acid catabolism - Google Patents

Construction of production strains for producing substituted phenols by specifically inactivating genes of the eugenol and ferulic acid catabolism Download PDF

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Publication number
CA2348962A1
CA2348962A1 CA002348962A CA2348962A CA2348962A1 CA 2348962 A1 CA2348962 A1 CA 2348962A1 CA 002348962 A CA002348962 A CA 002348962A CA 2348962 A CA2348962 A CA 2348962A CA 2348962 A1 CA2348962 A1 CA 2348962A1
Authority
CA
Canada
Prior art keywords
gene
inactivated
pseudomonas
eugenol
ferulic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002348962A
Other languages
English (en)
French (fr)
Inventor
Jurgen Rabenhorst
Alexander Steinbuchel
Horst Priefert
Jorg Overhage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symrise AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2348962A1 publication Critical patent/CA2348962A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01016—Acetyl-CoA C-acyltransferase (2.3.1.16)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
CA002348962A 1998-10-31 1999-10-20 Construction of production strains for producing substituted phenols by specifically inactivating genes of the eugenol and ferulic acid catabolism Abandoned CA2348962A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19850242.7 1998-10-31
DE19850242A DE19850242A1 (de) 1998-10-31 1998-10-31 Konstruktion von Produktionsstämmen für die Herstellung von substituierten Phenolen durch gezielte Inaktivierung von Genen des Eugenol- und Ferulasäure-Katabolismus
PCT/EP1999/007952 WO2000026355A2 (de) 1998-10-31 1999-10-20 Konstruktion von produktionsstämmen für die herstellung von substituierten phenolen durch gezielte inaktivierungen von genen des eugenol- und ferulasäure-katabolismus

Publications (1)

Publication Number Publication Date
CA2348962A1 true CA2348962A1 (en) 2000-05-11

Family

ID=7886266

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002348962A Abandoned CA2348962A1 (en) 1998-10-31 1999-10-20 Construction of production strains for producing substituted phenols by specifically inactivating genes of the eugenol and ferulic acid catabolism

Country Status (14)

Country Link
EP (1) EP1124947A2 (de)
JP (1) JP2003533166A (de)
KR (1) KR20020022045A (de)
CN (1) CN1325444A (de)
AU (1) AU761093B2 (de)
BR (1) BR9914930A (de)
CA (1) CA2348962A1 (de)
DE (1) DE19850242A1 (de)
HK (1) HK1041902A1 (de)
HU (1) HUP0104772A3 (de)
IL (1) IL142272A0 (de)
PL (1) PL348647A1 (de)
SK (1) SK5742001A3 (de)
WO (1) WO2000026355A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10036044B2 (en) 2013-07-22 2018-07-31 Basf Se Genetic engineering of Pseudomonas putida KT2440 for rapid and high yield production of vanillin from ferulic acid

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100830691B1 (ko) * 2006-11-21 2008-05-20 광주과학기술원 이소유제놀과 유제놀로부터 천연바닐린과 바닐린 산으로 생전환하는 신규 미생물
US9567618B2 (en) 2011-06-17 2017-02-14 Symrise Ag Microorganisms and methods for producing substituted phenols
CN103805640B (zh) * 2014-01-26 2016-04-06 东华大学 一种利用细菌氧化松伯醛制备阿魏酸的方法
PL3000888T3 (pl) * 2014-09-29 2019-05-31 Symrise Ag Sposób przekształcania kwasu ferulowego do waniliny
FR3041655B1 (fr) * 2015-09-29 2017-11-24 Lesaffre & Cie Nouvelles souches bacteriennes pour la production de vanilline
CN111019995B (zh) 2019-12-31 2021-04-27 厦门欧米克生物科技有限公司 一种以丁香酚为底物发酵生成香兰素的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05227980A (ja) * 1992-02-21 1993-09-07 Takasago Internatl Corp 発酵法によるバニリンおよびその関連化合物の製造法
DE4227076A1 (de) * 1992-08-17 1994-02-24 Haarmann & Reimer Gmbh Verfahren zur Herstellung substituierter Methoxyphenole und dafür geeignete Mikroorganismen
GB9606187D0 (en) * 1996-03-23 1996-05-29 Inst Of Food Research Production of vanillin
DE19649655A1 (de) * 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10036044B2 (en) 2013-07-22 2018-07-31 Basf Se Genetic engineering of Pseudomonas putida KT2440 for rapid and high yield production of vanillin from ferulic acid

Also Published As

Publication number Publication date
AU761093B2 (en) 2003-05-29
HK1041902A1 (zh) 2002-07-26
KR20020022045A (ko) 2002-03-23
DE19850242A1 (de) 2000-05-04
HUP0104772A2 (hu) 2002-03-28
HUP0104772A3 (en) 2003-10-28
AU1041300A (en) 2000-05-22
EP1124947A2 (de) 2001-08-22
SK5742001A3 (en) 2001-12-03
PL348647A1 (en) 2002-06-03
WO2000026355A3 (de) 2000-11-09
BR9914930A (pt) 2001-07-10
JP2003533166A (ja) 2003-11-11
CN1325444A (zh) 2001-12-05
WO2000026355A2 (de) 2000-05-11
IL142272A0 (en) 2002-03-10

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Legal Events

Date Code Title Description
FZDE Discontinued