KR20010015818A - 합성된 가변성 부분 및 변형 특이성을 가지는면역글로불린 분자 - Google Patents
합성된 가변성 부분 및 변형 특이성을 가지는면역글로불린 분자 Download PDFInfo
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- KR20010015818A KR20010015818A KR1020007005264A KR20007005264A KR20010015818A KR 20010015818 A KR20010015818 A KR 20010015818A KR 1020007005264 A KR1020007005264 A KR 1020007005264A KR 20007005264 A KR20007005264 A KR 20007005264A KR 20010015818 A KR20010015818 A KR 20010015818A
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3046—Stomach, Intestines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Mycology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6571697P | 1997-11-14 | 1997-11-14 | |
US60/065,716 | 1997-11-14 | ||
US8140398P | 1998-04-10 | 1998-04-10 | |
US60/081,403 | 1998-04-10 | ||
PCT/US1998/024302 WO1999025378A1 (en) | 1997-11-14 | 1998-11-13 | Immunoglobulin molecules having a synthetic variable region and modified specificity |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20010015818A true KR20010015818A (ko) | 2001-02-26 |
Family
ID=26745908
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020007005263A KR20010015817A (ko) | 1997-11-14 | 1998-11-13 | 항-이디오타입 반응을 유도하는 능력이 강화된 변형된 항체 |
KR1020007005264A KR20010015818A (ko) | 1997-11-14 | 1998-11-13 | 합성된 가변성 부분 및 변형 특이성을 가지는면역글로불린 분자 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020007005263A KR20010015817A (ko) | 1997-11-14 | 1998-11-13 | 항-이디오타입 반응을 유도하는 능력이 강화된 변형된 항체 |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP1032420A4 (ja) |
JP (2) | JP2002507544A (ja) |
KR (2) | KR20010015817A (ja) |
CN (2) | CN1294517A (ja) |
AU (2) | AU763029B2 (ja) |
BR (2) | BR9815580A (ja) |
CA (2) | CA2309990A1 (ja) |
IL (2) | IL136114A0 (ja) |
WO (2) | WO1999025378A1 (ja) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
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AU753753B2 (en) * | 1998-11-13 | 2002-10-24 | Euro-Celtique S.A. | Contraceptive antibody vaccines |
EP1092779B1 (en) * | 1999-10-11 | 2009-11-25 | Institut Pasteur | Lentiviral vectors for the preparation of immunotherapeutical compositions |
WO2001088159A2 (en) * | 2000-05-16 | 2001-11-22 | Euro-Celtique S.A. | Cd28 synthebody for the modulation of immune responses |
US7396917B2 (en) | 2000-12-05 | 2008-07-08 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
AU2002234001B2 (en) * | 2000-12-05 | 2008-05-01 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
GB0103174D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Plc | Novel method of treatment |
US20040143101A1 (en) * | 2001-04-02 | 2004-07-22 | Soltis Daniel A. | Immunoglobulin construct containing anti-mucin variable domain sequences for eliciting an anti-idiotype anti-tumor response |
WO2003063768A2 (en) * | 2001-10-25 | 2003-08-07 | Euro-Celtique S.A. | Compositions and methods directed to anthrax toxin |
EP1938834B1 (en) * | 2002-04-09 | 2012-04-25 | The Curators Of The University Of Missouri | Treatment of type 1 diabetes before and after expression of predisposition markers |
NZ571508A (en) | 2002-05-24 | 2010-05-28 | Schering Corp | Neutralizing human anti-IGFR antibody |
TWI323265B (en) | 2002-08-06 | 2010-04-11 | Glaxo Group Ltd | Antibodies |
NZ538996A (en) | 2002-10-31 | 2008-04-30 | Genentech Inc | Methods and compositions for increasing antibody production |
GB0306309D0 (en) | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
WO2005021595A1 (en) * | 2003-08-28 | 2005-03-10 | Euro-Celtique S.A. | Methods of antibody engineering using antibody display rules |
CN1938428A (zh) | 2003-11-12 | 2007-03-28 | 先灵公司 | 多基因表达的质粒系统 |
PE20050928A1 (es) | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
US20090208486A1 (en) * | 2004-03-09 | 2009-08-20 | Makoto Taketo | Pharmaceutical composition comprising cxcr3 inhibitor |
US7811562B2 (en) | 2004-12-03 | 2010-10-12 | Schering Corporation | Biomarkers for pre-selection of patients for anti-IGF1R therapy |
UA99714C2 (ru) * | 2006-08-28 | 2012-09-25 | Ля Хойя Інстітьют Фор Еллерджи Енд Іммьюнолоджи | Моноклональное антитело, которое специфически связывается с light |
GB0706070D0 (en) * | 2007-03-28 | 2007-05-09 | Scancell Ltd | Nucleic acids |
KR101203777B1 (ko) * | 2008-03-12 | 2012-11-21 | 임클론 엘엘씨 | 항-tyrp1 항체 |
EP2799453B1 (en) * | 2009-04-29 | 2019-04-03 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | ERG2 monoclonal antibodies and their therapeutic use |
CN102816240B (zh) * | 2011-03-08 | 2014-02-12 | 中国人民解放军第三军医大学第二附属医院 | 一种融合蛋白及其融合蛋白表达载体 |
EP2714083A4 (en) * | 2011-05-27 | 2015-03-04 | Fox Chase Cancer Ct | RATIONAL-DESIGNED TYPE II RECEPTOR ANTIBODIES WITH A MULLERIAN-INHIBITABLE SUBSTANCE |
MY188083A (en) * | 2011-11-23 | 2021-11-16 | In3Bio Ltd | Recombinant proteins and their therapeutic uses |
JP5437525B1 (ja) | 2012-12-28 | 2014-03-12 | 株式会社ナード研究所 | チロシン誘導体およびチロシン誘導体の製造方法 |
US20160206732A1 (en) * | 2013-05-14 | 2016-07-21 | Shanghai Hycharm Inc. | Epitope vaccine for low immunogenic protein and preparing method and usage thereof |
CN103275914B (zh) * | 2013-06-03 | 2015-04-01 | 中国人民解放军军事医学科学院微生物流行病研究所 | 展示保护性抗原的细菌菌蜕及其应用 |
CN105263953B (zh) * | 2014-01-15 | 2020-01-07 | 勃林格殷格翰动物保健美国有限公司 | 猪细小病毒5a、使用方法及疫苗 |
JP6705755B2 (ja) * | 2014-05-19 | 2020-06-03 | バロ セラピューティクス オイValo Therapeutics Oy | 癌ワクチン開発のための改変アデノウイルス |
CN105693859B (zh) * | 2016-03-22 | 2019-06-21 | 苏州莱泰生物科技有限公司 | 抗人g2a单克隆抗体以及检测人巨噬细胞g2a表达量的试剂盒 |
CN111978382B (zh) * | 2020-09-03 | 2022-03-04 | 吉林大学第一医院 | 一种球形孢子丝菌Gp70重组蛋白的制备方法及其应用 |
CN112646029B (zh) * | 2020-12-30 | 2022-07-29 | 深圳清华大学研究院 | 成熟脑源性神经营养因子的抗体及其应用和诊断试剂盒 |
CN115856296B (zh) * | 2022-12-16 | 2023-07-25 | 华北理工大学 | 抗志贺氏菌的单克隆抗体及其检测中的应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5688657A (en) * | 1988-03-31 | 1997-11-18 | International Bio-Immune Systems, Inc. | Monoclonal antibodies against human colon carcinoma-associated antigens and uses therefor |
EP0460076B1 (en) * | 1989-02-24 | 1995-11-29 | The Regents Of The University Of California | Genetically engineered immunoglobulins |
GB9019553D0 (en) * | 1990-09-07 | 1990-10-24 | Unilever Plc | Specific binding agents |
GB9109645D0 (en) * | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
GB9223084D0 (en) * | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
CA2149529C (en) * | 1992-11-16 | 2006-05-02 | Fernado J. R. Do Couto | Peptides and anti-sense peptides with broad neoplastic specificity |
WO1994014847A1 (en) * | 1992-12-24 | 1994-07-07 | The Regents Of The University Of California | Genetically engineered immunoglobulins |
WO1994014848A1 (en) * | 1992-12-24 | 1994-07-07 | The Regents Of The University Of California | Genetically engineered immunoglobulins |
US5476784A (en) * | 1993-04-06 | 1995-12-19 | Rice; Peter A. | Gonococcal anti-idiotypic antibodies and methods and compositions using them |
US5653977A (en) * | 1993-09-09 | 1997-08-05 | Uab Research Foundation | Anti-idiotypic antibody that mimics the GD2 antigen |
US5624904A (en) * | 1993-11-17 | 1997-04-29 | Massachusetts Institute Of Technology | Method for treating gram positive septicemia |
-
1998
- 1998-11-13 BR BR9815580-6A patent/BR9815580A/pt not_active IP Right Cessation
- 1998-11-13 IL IL13611498A patent/IL136114A0/xx unknown
- 1998-11-13 KR KR1020007005263A patent/KR20010015817A/ko not_active Application Discontinuation
- 1998-11-13 IL IL13611398A patent/IL136113A0/xx unknown
- 1998-11-13 EP EP98958583A patent/EP1032420A4/en not_active Withdrawn
- 1998-11-13 WO PCT/US1998/024302 patent/WO1999025378A1/en not_active Application Discontinuation
- 1998-11-13 KR KR1020007005264A patent/KR20010015818A/ko not_active Application Discontinuation
- 1998-11-13 WO PCT/US1998/024303 patent/WO1999025379A1/en not_active Application Discontinuation
- 1998-11-13 AU AU14597/99A patent/AU763029B2/en not_active Ceased
- 1998-11-13 CN CN98813117A patent/CN1294517A/zh active Pending
- 1998-11-13 JP JP2000520812A patent/JP2002507544A/ja active Pending
- 1998-11-13 CA CA002309990A patent/CA2309990A1/en not_active Abandoned
- 1998-11-13 CN CN98813119A patent/CN1327388A/zh active Pending
- 1998-11-13 CA CA002310269A patent/CA2310269A1/en not_active Abandoned
- 1998-11-13 EP EP98958584A patent/EP1030684A4/en not_active Withdrawn
- 1998-11-13 BR BR9815289-0A patent/BR9815289A/pt not_active IP Right Cessation
- 1998-11-13 JP JP2000520811A patent/JP2001526021A/ja active Pending
-
2003
- 2003-10-10 AU AU2003252902A patent/AU2003252902A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20010015817A (ko) | 2001-02-26 |
AU2003252902A1 (en) | 2003-11-06 |
CN1327388A (zh) | 2001-12-19 |
AU763029B2 (en) | 2003-07-10 |
EP1032420A1 (en) | 2000-09-06 |
AU1459799A (en) | 1999-06-07 |
CN1294517A (zh) | 2001-05-09 |
WO1999025378A9 (en) | 1999-08-12 |
JP2002507544A (ja) | 2002-03-12 |
WO1999025379A1 (en) | 1999-05-27 |
CA2309990A1 (en) | 1999-05-27 |
EP1030684A4 (en) | 2004-09-15 |
AU1459899A (en) | 1999-06-07 |
IL136113A0 (en) | 2001-05-20 |
EP1030684A1 (en) | 2000-08-30 |
JP2001526021A (ja) | 2001-12-18 |
EP1032420A4 (en) | 2004-09-15 |
AU737457B2 (en) | 2001-08-23 |
BR9815580A (pt) | 2002-01-29 |
BR9815289A (pt) | 2001-12-26 |
IL136114A0 (en) | 2001-05-20 |
WO1999025378A1 (en) | 1999-05-27 |
CA2310269A1 (en) | 1999-05-27 |
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