KR20000071167A - 담즙산 흡착 효과를 갖는 가교결합된 비닐 중합체 - Google Patents

담즙산 흡착 효과를 갖는 가교결합된 비닐 중합체 Download PDF

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Publication number
KR20000071167A
KR20000071167A KR1019997007457A KR19997007457A KR20000071167A KR 20000071167 A KR20000071167 A KR 20000071167A KR 1019997007457 A KR1019997007457 A KR 1019997007457A KR 19997007457 A KR19997007457 A KR 19997007457A KR 20000071167 A KR20000071167 A KR 20000071167A
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KR
South Korea
Prior art keywords
independently
formula
compound
mmol
mixture
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KR1019997007457A
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English (en)
Korean (ko)
Inventor
폰젝게른하인케
호프만악셀
팔크오이겐
회르쉬브리깃테
린키스아돌프하인츠
글롬빅하이너
Original Assignee
아벤티스 레제아르히 운트 테히놀로기스 게엠베하 운트 콤파니 카게
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Application filed by 아벤티스 레제아르히 운트 테히놀로기스 게엠베하 운트 콤파니 카게 filed Critical 아벤티스 레제아르히 운트 테히놀로기스 게엠베하 운트 콤파니 카게
Publication of KR20000071167A publication Critical patent/KR20000071167A/ko

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F271/00—Macromolecular compounds obtained by polymerising monomers on to polymers of nitrogen-containing monomers as defined in group C08F26/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C08F20/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F22/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof
    • C08F22/10—Esters
    • C08F22/1006—Esters of polyhydric alcohols or polyhydric phenols, e.g. ethylene glycol dimethacrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F22/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof
    • C08F22/36—Amides or imides
    • C08F22/38—Amides
    • C08F22/385—Monomers containing two or more (meth)acrylamide groups, e.g. N,N'-methylenebisacrylamide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019997007457A 1997-02-17 1998-02-17 담즙산 흡착 효과를 갖는 가교결합된 비닐 중합체 KR20000071167A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19705963A DE19705963A1 (de) 1997-02-17 1997-02-17 Vernetzte Vinylpolymere mit Gallensäure-Adsorberwirkung
DE19705963.5 1997-02-17

Publications (1)

Publication Number Publication Date
KR20000071167A true KR20000071167A (ko) 2000-11-25

Family

ID=7820445

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019997007457A KR20000071167A (ko) 1997-02-17 1998-02-17 담즙산 흡착 효과를 갖는 가교결합된 비닐 중합체

Country Status (14)

Country Link
EP (1) EP0960141A1 (tr)
JP (1) JP2002515930A (tr)
KR (1) KR20000071167A (tr)
CN (1) CN1251112A (tr)
AU (1) AU728985B2 (tr)
BR (1) BR9807408A (tr)
CA (1) CA2281602A1 (tr)
CZ (1) CZ293299A3 (tr)
DE (1) DE19705963A1 (tr)
HU (1) HUP0001012A3 (tr)
PL (1) PL335106A1 (tr)
RU (1) RU99119911A (tr)
TR (1) TR199901978T2 (tr)
WO (1) WO1998036002A1 (tr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4369499A (en) * 1998-06-30 2000-01-17 Aventis Research & Technologies Gmbh & Co. Kg Novel method for producing cross-linked vinyl polymers based on quaternary ammonium groups exhibiting a bile acid adsorbent effect
US6958212B1 (en) 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
AU773914B2 (en) 1999-02-01 2004-06-10 Eidgenossische Technische Hochschule Zurich Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups
US7291673B2 (en) 2000-06-02 2007-11-06 Eidgenossiche Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US8282912B2 (en) 2002-03-22 2012-10-09 Kuros Biosurgery, AG Compositions for tissue augmentation
JP2005054145A (ja) 2003-08-07 2005-03-03 Mitsubishi Gas Chem Co Inc ガスバリア性（メタ）アクリレート樹脂硬化物および塗料、接着剤、フィルム
CN101711168B (zh) 2007-04-13 2013-05-01 库罗斯生物外科股份公司 聚合物组织封闭剂
JP6126498B2 (ja) * 2013-02-15 2017-05-10 富士フイルム株式会社 高分子機能性膜及びその製造方法
JP6071957B2 (ja) * 2014-03-07 2017-02-01 富士フイルム株式会社 イオン交換性ポリマーおよびその製造方法、電解質膜およびその製造方法ならびにイオン交換性ポリマー製造用組成物
WO2017038328A1 (ja) * 2015-08-31 2017-03-09 富士フイルム株式会社 イオン交換ポリマー、硬化性組成物、硬化物、部材、及び、装置
US11214759B2 (en) 2017-09-15 2022-01-04 Lg Chem, Ltd. Polymerizable composition, polymer capsule and fabric softener composition comprising the same
CN110317588A (zh) * 2018-03-29 2019-10-11 中国石油化工股份有限公司 一种阳离子表面活性剂及其制备方法和起泡剂及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206115A1 (es) * 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado
GB9123683D0 (en) * 1991-11-07 1992-01-02 Sandoz Ltd Improvements in or relating to organic compounds
WO1994001474A1 (en) * 1992-07-06 1994-01-20 Otsuka Kagaku Kabushiki Kaisha Polymerizable monomer, polymer thereof, and process for producing the same
ES2110543T3 (es) * 1992-07-22 1998-02-16 Hoechst Ag Derivados de poli(vinil-aminas) que tienen centros hidrofilos, procedimiento para su preparacion asi como la utilizacion de los compuestos como medicamentos, vehiculos de sustancias activas e ingredientes auxiliares para alimentos.
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor

Also Published As

Publication number Publication date
JP2002515930A (ja) 2002-05-28
WO1998036002A1 (de) 1998-08-20
CA2281602A1 (en) 1998-08-20
AU728985B2 (en) 2001-01-25
AU6498398A (en) 1998-09-08
TR199901978T2 (tr) 2000-06-21
DE19705963A1 (de) 1998-08-20
PL335106A1 (en) 2000-04-10
CZ293299A3 (cs) 1999-12-15
HUP0001012A2 (hu) 2000-09-28
EP0960141A1 (de) 1999-12-01
BR9807408A (pt) 2000-03-14
RU99119911A (ru) 2001-06-27
CN1251112A (zh) 2000-04-19
HUP0001012A3 (en) 2001-11-28

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