KR20000057136A - 연골세포에 전단류 응력의 인가 - Google Patents

연골세포에 전단류 응력의 인가 Download PDF

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Publication number
KR20000057136A
KR20000057136A KR1019990704403A KR19997004403A KR20000057136A KR 20000057136 A KR20000057136 A KR 20000057136A KR 1019990704403 A KR1019990704403 A KR 1019990704403A KR 19997004403 A KR19997004403 A KR 19997004403A KR 20000057136 A KR20000057136 A KR 20000057136A
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KR
South Korea
Prior art keywords
cells
shear flow
substrate
chondrocytes
bioreactor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019990704403A
Other languages
English (en)
Korean (ko)
Inventor
드롤 셀릭타
노우신 듄켈만
앨빈 이. 피터슨
론다 이. 슈라이버
제인 윌로우비
게일 케이. 노튼
Original Assignee
나우톤 질 케이.
어드밴스드 티슈 사이언스, 인코퍼레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 나우톤 질 케이., 어드밴스드 티슈 사이언스, 인코퍼레이티드 filed Critical 나우톤 질 케이.
Publication of KR20000057136A publication Critical patent/KR20000057136A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Excavating Of Shafts Or Tunnels (AREA)
  • Lubricants (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Materials For Medical Uses (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019990704403A 1996-11-20 1997-11-18 연골세포에 전단류 응력의 인가 Ceased KR20000057136A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/753,104 US5928945A (en) 1996-11-20 1996-11-20 Application of shear flow stress to chondrocytes or chondrocyte stem cells to produce cartilage
US8/753,104 1996-11-20

Publications (1)

Publication Number Publication Date
KR20000057136A true KR20000057136A (ko) 2000-09-15

Family

ID=25029173

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019990704403A Ceased KR20000057136A (ko) 1996-11-20 1997-11-18 연골세포에 전단류 응력의 인가

Country Status (11)

Country Link
US (1) US5928945A (enExample)
EP (1) EP1019489B1 (enExample)
JP (1) JP4014645B2 (enExample)
KR (1) KR20000057136A (enExample)
AT (1) ATE273382T1 (enExample)
AU (1) AU744686B2 (enExample)
CA (1) CA2272547A1 (enExample)
DE (1) DE69730251T2 (enExample)
ES (1) ES2225999T3 (enExample)
NZ (1) NZ335991A (enExample)
WO (1) WO1998022573A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100581728B1 (ko) * 2004-03-11 2006-05-22 부산대학교 산학협력단 골세포 배양기

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Also Published As

Publication number Publication date
ES2225999T3 (es) 2005-03-16
WO1998022573A1 (en) 1998-05-28
AU5445198A (en) 1998-06-10
EP1019489A4 (en) 2002-08-28
DE69730251T2 (de) 2005-09-15
CA2272547A1 (en) 1998-05-28
EP1019489B1 (en) 2004-08-11
US5928945A (en) 1999-07-27
ATE273382T1 (de) 2004-08-15
JP4014645B2 (ja) 2007-11-28
DE69730251D1 (de) 2004-09-16
NZ335991A (en) 2000-07-28
AU744686B2 (en) 2002-02-28
JP2001504697A (ja) 2001-04-10
EP1019489A1 (en) 2000-07-19

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