ATE273382T1 - Anwendung von scherflussbeanspruchung auf chondrozyten - Google Patents

Anwendung von scherflussbeanspruchung auf chondrozyten

Info

Publication number
ATE273382T1
ATE273382T1 AT97948366T AT97948366T ATE273382T1 AT E273382 T1 ATE273382 T1 AT E273382T1 AT 97948366 T AT97948366 T AT 97948366T AT 97948366 T AT97948366 T AT 97948366T AT E273382 T1 ATE273382 T1 AT E273382T1
Authority
AT
Austria
Prior art keywords
cells
cartilage
shear flow
substrate
produce
Prior art date
Application number
AT97948366T
Other languages
English (en)
Inventor
Dror Seliktar
Noushin Dunkelman
Alvin E Peterson
Rhonda E Schreiber
Jane Willoughby
Gail K Naughton
Original Assignee
Smith & Nephew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith & Nephew filed Critical Smith & Nephew
Application granted granted Critical
Publication of ATE273382T1 publication Critical patent/ATE273382T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Mechanical Engineering (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Excavating Of Shafts Or Tunnels (AREA)
  • Lubricants (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
AT97948366T 1996-11-20 1997-11-18 Anwendung von scherflussbeanspruchung auf chondrozyten ATE273382T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/753,104 US5928945A (en) 1996-11-20 1996-11-20 Application of shear flow stress to chondrocytes or chondrocyte stem cells to produce cartilage
PCT/US1997/021088 WO1998022573A1 (en) 1996-11-20 1997-11-18 Application of shear flow stress to chondrocytes

Publications (1)

Publication Number Publication Date
ATE273382T1 true ATE273382T1 (de) 2004-08-15

Family

ID=25029173

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97948366T ATE273382T1 (de) 1996-11-20 1997-11-18 Anwendung von scherflussbeanspruchung auf chondrozyten

Country Status (11)

Country Link
US (1) US5928945A (de)
EP (1) EP1019489B1 (de)
JP (1) JP4014645B2 (de)
KR (1) KR20000057136A (de)
AT (1) ATE273382T1 (de)
AU (1) AU744686B2 (de)
CA (1) CA2272547A1 (de)
DE (1) DE69730251T2 (de)
ES (1) ES2225999T3 (de)
NZ (1) NZ335991A (de)
WO (1) WO1998022573A1 (de)

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Also Published As

Publication number Publication date
KR20000057136A (ko) 2000-09-15
AU5445198A (en) 1998-06-10
EP1019489A4 (de) 2002-08-28
DE69730251D1 (de) 2004-09-16
JP2001504697A (ja) 2001-04-10
EP1019489A1 (de) 2000-07-19
AU744686B2 (en) 2002-02-28
JP4014645B2 (ja) 2007-11-28
US5928945A (en) 1999-07-27
DE69730251T2 (de) 2005-09-15
ES2225999T3 (es) 2005-03-16
CA2272547A1 (en) 1998-05-28
WO1998022573A1 (en) 1998-05-28
EP1019489B1 (de) 2004-08-11
NZ335991A (en) 2000-07-28

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