KR20000036102A - 파르네실-단백질 트랜스퍼라제 억제제로서 유용한 치환된 벤조사이클로헵타피리딘 - Google Patents
파르네실-단백질 트랜스퍼라제 억제제로서 유용한 치환된 벤조사이클로헵타피리딘 Download PDFInfo
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- KR20000036102A KR20000036102A KR1019997002121A KR19997002121A KR20000036102A KR 20000036102 A KR20000036102 A KR 20000036102A KR 1019997002121 A KR1019997002121 A KR 1019997002121A KR 19997002121 A KR19997002121 A KR 19997002121A KR 20000036102 A KR20000036102 A KR 20000036102A
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- compound
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Pyridine Compounds (AREA)
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| US71370596A | 1996-09-13 | 1996-09-13 | |
| US8/713,705 | 1996-09-13 |
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|---|---|
| KR20000036102A true KR20000036102A (ko) | 2000-06-26 |
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| KR1019997002121A Withdrawn KR20000036102A (ko) | 1996-09-13 | 1997-09-11 | 파르네실-단백질 트랜스퍼라제 억제제로서 유용한 치환된 벤조사이클로헵타피리딘 |
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| JP (1) | JP2001500506A (enExample) |
| KR (1) | KR20000036102A (enExample) |
| CN (1) | CN1104428C (enExample) |
| AT (1) | ATE294172T1 (enExample) |
| AU (1) | AU4337597A (enExample) |
| CA (1) | CA2264666A1 (enExample) |
| DE (1) | DE69733142T2 (enExample) |
| ES (1) | ES2242232T3 (enExample) |
| HU (1) | HUP0000073A3 (enExample) |
| IL (1) | IL128926A0 (enExample) |
| NZ (1) | NZ334341A (enExample) |
| WO (1) | WO1998011097A1 (enExample) |
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| US6613905B1 (en) | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| CA2318088A1 (en) | 1998-01-21 | 1999-07-29 | Yoshisuke Nakasato | Chemokine receptor antagonists and methods of use therefor |
| US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| CN1289336A (zh) | 1998-01-21 | 2001-03-28 | 千禧药品公司 | 趋化因子受体拮抗剂和其使用方法 |
| US6503926B2 (en) | 1998-09-04 | 2003-01-07 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6288083B1 (en) | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
| EP1656156A2 (en) | 2003-08-13 | 2006-05-17 | Children's Hospital Medical Center | Mobilization of hematopoietic cells |
| ATE524445T1 (de) | 2005-06-23 | 2011-09-15 | Merck Sharp & Dohme | Benzocycloheptapyridine als inhibitoren der tyrosinkinase met |
| TW200813021A (en) | 2006-07-10 | 2008-03-16 | Merck & Co Inc | Tyrosine kinase inhibitors |
| CA2657247A1 (en) | 2006-07-28 | 2008-01-31 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| CA2704684A1 (en) | 2007-11-07 | 2009-05-14 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| WO2010005782A1 (en) | 2008-07-10 | 2010-01-14 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the cb2 receptor |
| PE20110397A1 (es) | 2008-09-25 | 2011-07-01 | Boehringer Ingelheim Int | Compuestos que modulan selectivamente el receptor cb2 |
| EP2398771B1 (en) | 2009-02-18 | 2015-07-29 | Boehringer Ingelheim International GmbH | Heterocyclic compounds which modulate the cb2 receptor |
| US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
| WO2010147791A1 (en) * | 2009-06-16 | 2010-12-23 | Boehringer Ingelheim International Gmbh | Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor |
| JP2013505295A (ja) | 2009-09-22 | 2013-02-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｂ２受容体を選択的に調節する化合物 |
| WO2011088015A1 (en) | 2010-01-15 | 2011-07-21 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| EP2542539B1 (en) | 2010-03-05 | 2014-02-26 | Boehringer Ingelheim International GmbH | Tetrazole compounds which selectively modulate the cb2 receptor |
| WO2012012307A1 (en) | 2010-07-22 | 2012-01-26 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the cb2 rece |
| EP2803668A1 (en) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles |
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| GB1593417A (en) * | 1976-12-22 | 1981-07-15 | Squibb & Sons Inc | Carbocyclic-fused pyrazolopyridine derivatives |
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| IL98572A (en) * | 1990-06-22 | 1995-07-31 | Schering Corp | Bis-benzo or benzopyrido cyclohepta piperidene, piperidylidene and piperazine compositions an methods of use |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| NZ274749A (en) * | 1993-10-15 | 1998-05-27 | Schering Corp | Tricyclic carbamate derivatives useful for inhibition of g-protein function and for treating proliferative diseases, medicaments |
-
1997
- 1997-09-11 AT AT97941476T patent/ATE294172T1/de not_active IP Right Cessation
- 1997-09-11 JP JP10513761A patent/JP2001500506A/ja not_active Ceased
- 1997-09-11 AU AU43375/97A patent/AU4337597A/en not_active Abandoned
- 1997-09-11 IL IL12892697A patent/IL128926A0/xx unknown
- 1997-09-11 DE DE69733142T patent/DE69733142T2/de not_active Expired - Fee Related
- 1997-09-11 CA CA002264666A patent/CA2264666A1/en not_active Abandoned
- 1997-09-11 CN CN97199528A patent/CN1104428C/zh not_active Expired - Fee Related
- 1997-09-11 ES ES97941476T patent/ES2242232T3/es not_active Expired - Lifetime
- 1997-09-11 WO PCT/US1997/015902 patent/WO1998011097A1/en not_active Ceased
- 1997-09-11 HU HU0000073A patent/HUP0000073A3/hu unknown
- 1997-09-11 EP EP97941476A patent/EP0931077B1/en not_active Expired - Lifetime
- 1997-09-11 KR KR1019997002121A patent/KR20000036102A/ko not_active Withdrawn
- 1997-09-11 NZ NZ334341A patent/NZ334341A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0000073A3 (en) | 2002-02-28 |
| CN1236365A (zh) | 1999-11-24 |
| CA2264666A1 (en) | 1998-03-19 |
| DE69733142D1 (de) | 2005-06-02 |
| ATE294172T1 (de) | 2005-05-15 |
| ES2242232T3 (es) | 2005-11-01 |
| CN1104428C (zh) | 2003-04-02 |
| AU4337597A (en) | 1998-04-02 |
| JP2001500506A (ja) | 2001-01-16 |
| EP0931077B1 (en) | 2005-04-27 |
| DE69733142T2 (de) | 2006-03-16 |
| WO1998011097A1 (en) | 1998-03-19 |
| NZ334341A (en) | 2001-01-26 |
| IL128926A0 (en) | 2000-02-17 |
| EP0931077A1 (en) | 1999-07-28 |
| HUP0000073A2 (hu) | 2001-10-28 |
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Patent event date: 19990312 Patent event code: PA01051R01D Comment text: International Patent Application |
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