AU4337597A - Substituted benzocycloheptapyridine useful as inhibitors of farnesyl-protein tr ansferase - Google Patents

Substituted benzocycloheptapyridine useful as inhibitors of farnesyl-protein tr ansferase

Info

Publication number
AU4337597A
AU4337597A AU43375/97A AU4337597A AU4337597A AU 4337597 A AU4337597 A AU 4337597A AU 43375/97 A AU43375/97 A AU 43375/97A AU 4337597 A AU4337597 A AU 4337597A AU 4337597 A AU4337597 A AU 4337597A
Authority
AU
Australia
Prior art keywords
inhibitors
farnesyl
ansferase
protein
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU43375/97A
Other languages
English (en)
Inventor
Alan B. Cooper
Ronald J. Doll
Alan K. Mallams
F. George Njoroge
Dinanath F. Rane
Arthur G. Taveras
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU4337597A publication Critical patent/AU4337597A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
AU43375/97A 1996-09-13 1997-09-11 Substituted benzocycloheptapyridine useful as inhibitors of farnesyl-protein tr ansferase Abandoned AU4337597A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71370596A 1996-09-13 1996-09-13
US08713705 1996-09-13
PCT/US1997/015902 WO1998011097A1 (en) 1996-09-13 1997-09-11 Substituted benzocycloheptapyridine useful as inhibitors of farnesyl-protein transferase

Publications (1)

Publication Number Publication Date
AU4337597A true AU4337597A (en) 1998-04-02

Family

ID=24867191

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43375/97A Abandoned AU4337597A (en) 1996-09-13 1997-09-11 Substituted benzocycloheptapyridine useful as inhibitors of farnesyl-protein tr ansferase

Country Status (13)

Country Link
EP (1) EP0931077B1 (enExample)
JP (1) JP2001500506A (enExample)
KR (1) KR20000036102A (enExample)
CN (1) CN1104428C (enExample)
AT (1) ATE294172T1 (enExample)
AU (1) AU4337597A (enExample)
CA (1) CA2264666A1 (enExample)
DE (1) DE69733142T2 (enExample)
ES (1) ES2242232T3 (enExample)
HU (1) HUP0000073A3 (enExample)
IL (1) IL128926A0 (enExample)
NZ (1) NZ334341A (enExample)
WO (1) WO1998011097A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6433165B1 (en) 1998-01-21 2002-08-13 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6613905B1 (en) 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
WO1999037651A1 (en) 1998-01-21 1999-07-29 Millenium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7271176B2 (en) 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US6503926B2 (en) 1998-09-04 2003-01-07 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6288083B1 (en) 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor
WO2005017160A2 (en) 2003-08-13 2005-02-24 Children's Hospital Medical Center Mobilization of hematopoietic cells
DK1896421T3 (da) 2005-06-23 2012-01-09 Merck Sharp & Dohme Benzocyclohetapyridiner som hæmmere af receptoren tyrosinkinase MET
TW200813021A (en) 2006-07-10 2008-03-16 Merck & Co Inc Tyrosine kinase inhibitors
JP5448164B2 (ja) 2006-07-28 2014-03-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂ２受容体を変調する化合物
EP2217565B1 (en) 2007-11-07 2013-05-22 Boehringer Ingelheim International GmbH Compounds which modulate the cb2 receptor
JP5749162B2 (ja) 2008-07-10 2015-07-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂ２受容体を調節するスルホン化合物
AP2011005674A0 (en) 2008-09-25 2011-04-30 Boehringer Ingelheim Int Sulfonyl compounds which selectively modulate the CB2 receptor.
JP5705748B2 (ja) 2009-02-18 2015-04-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂ２受容体を変調する複素環化合物
US8299103B2 (en) 2009-06-15 2012-10-30 Boehringer Ingelheim International Gmbh Compounds which selectively modulate the CB2 receptor
EP2443107B1 (en) 2009-06-16 2018-08-08 Boehringer Ingelheim International GmbH Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor
JP2013505295A (ja) 2009-09-22 2013-02-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂ２受容体を選択的に調節する化合物
EP2523936A1 (en) 2010-01-15 2012-11-21 Boehringer Ingelheim International GmbH Compounds which modulate the cb2 receptor
EP2542539B1 (en) 2010-03-05 2014-02-26 Boehringer Ingelheim International GmbH Tetrazole compounds which selectively modulate the cb2 receptor
US8846936B2 (en) 2010-07-22 2014-09-30 Boehringer Ingelheim International Gmbh Sulfonyl compounds which modulate the CB2 receptor
EP2803668A1 (en) 2013-05-17 2014-11-19 Boehringer Ingelheim International Gmbh Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593417A (en) * 1976-12-22 1981-07-15 Squibb & Sons Inc Carbocyclic-fused pyrazolopyridine derivatives
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
NZ238629A (en) * 1990-06-22 1993-09-27 Schering Corp Bis-benzo- or benzopyrido-cyclohepta (where z is c, o, s or n) piperidine, piperidylidene or piperazine compounds, medicaments and methods of preparation
AU699043B2 (en) * 1993-10-15 1998-11-19 Schering Corporation Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them

Also Published As

Publication number Publication date
NZ334341A (en) 2001-01-26
HUP0000073A3 (en) 2002-02-28
CN1236365A (zh) 1999-11-24
CN1104428C (zh) 2003-04-02
EP0931077B1 (en) 2005-04-27
ATE294172T1 (de) 2005-05-15
EP0931077A1 (en) 1999-07-28
DE69733142T2 (de) 2006-03-16
ES2242232T3 (es) 2005-11-01
HUP0000073A2 (hu) 2001-10-28
DE69733142D1 (de) 2005-06-02
WO1998011097A1 (en) 1998-03-19
IL128926A0 (en) 2000-02-17
CA2264666A1 (en) 1998-03-19
JP2001500506A (ja) 2001-01-16
KR20000036102A (ko) 2000-06-26

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted