KR102899289B1 - 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제 - Google Patents

줄기 세포에서 유래된 망막색소상피의 macs 기반 정제

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Publication number
KR102899289B1
KR102899289B1 KR1020187009885A KR20187009885A KR102899289B1 KR 102899289 B1 KR102899289 B1 KR 102899289B1 KR 1020187009885 A KR1020187009885 A KR 1020187009885A KR 20187009885 A KR20187009885 A KR 20187009885A KR 102899289 B1 KR102899289 B1 KR 102899289B1
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cells
rpe
cell
cell population
positive
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KR20180042436A (ko
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네이던 메이어
루카스 체이스
케이시 스탄케비츠
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후지필름 셀룰러 다이내믹스, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

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  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
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  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020187009885A 2015-09-08 2016-09-07 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제 Active KR102899289B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257040966A KR20260003355A (ko) 2015-09-08 2016-09-07 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562215272P 2015-09-08 2015-09-08
US62/215,272 2015-09-08
PCT/US2016/050554 WO2017044488A1 (en) 2015-09-08 2016-09-07 Macs-based purification of stem cell-derived retinal pigment epithelium

Related Child Applications (1)

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KR1020257040966A Division KR20260003355A (ko) 2015-09-08 2016-09-07 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제

Publications (2)

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KR20180042436A KR20180042436A (ko) 2018-04-25
KR102899289B1 true KR102899289B1 (ko) 2025-12-15

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KR1020187009885A Active KR102899289B1 (ko) 2015-09-08 2016-09-07 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제
KR1020257040966A Pending KR20260003355A (ko) 2015-09-08 2016-09-07 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제

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US (3) US11162070B2 (enExample)
EP (2) EP4001402A1 (enExample)
JP (3) JP6986016B2 (enExample)
KR (2) KR102899289B1 (enExample)
CN (2) CN108291206B (enExample)
AU (1) AU2016318774B2 (enExample)
CA (1) CA2997763A1 (enExample)
DK (1) DK3347457T3 (enExample)
ES (1) ES2903442T3 (enExample)
LT (1) LT3347457T (enExample)
WO (1) WO2017044488A1 (enExample)

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TW202130806A (zh) 2019-10-30 2021-08-16 安斯泰來再生醫藥協會 用於產生視網膜色素上皮細胞之方法
US20230201267A1 (en) * 2020-05-29 2023-06-29 FUJIFILM Cellular Dynamics, Inc. Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof
KR20230159550A (ko) 2021-03-25 2023-11-21 블루록 테라퓨틱스 엘피 유도 만능 줄기 세포 수득 방법
CA3220602A1 (en) * 2021-05-28 2022-12-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods to generate macular, central and peripheral retinal pigment epithelial cells
CN115873797B (zh) * 2021-09-29 2024-08-13 北京干细胞与再生医学研究院 一种视网膜色素上皮细胞的扩增培养基及培养方法
JP2025508776A (ja) * 2022-02-22 2025-04-10 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 人工セルトリ細胞およびその人工セルトリ細胞を産生するための方法
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US20250011714A1 (en) 2025-01-09
CN108291206A (zh) 2018-07-17
EP4001402A1 (en) 2022-05-25
AU2016318774B2 (en) 2022-08-18
CN114717188B (zh) 2025-10-28
US11162070B2 (en) 2021-11-02
EP3347457B1 (en) 2021-10-27
JP2021184742A (ja) 2021-12-09
AU2016318774A1 (en) 2018-03-08
WO2017044488A1 (en) 2017-03-16
US20170067017A1 (en) 2017-03-09
DK3347457T3 (da) 2022-01-17
EP3347457A1 (en) 2018-07-18
CA2997763A1 (en) 2017-03-16
ES2903442T3 (es) 2022-04-01
KR20180042436A (ko) 2018-04-25
CN114717188A (zh) 2022-07-08
JP2023162277A (ja) 2023-11-08
JP2018526032A (ja) 2018-09-13
LT3347457T (lt) 2022-02-10
US12241083B2 (en) 2025-03-04
JP6986016B2 (ja) 2021-12-22
US20220033770A1 (en) 2022-02-03
KR20260003355A (ko) 2026-01-06
CN108291206B (zh) 2022-07-08

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