DK3347457T3 - MACS-baseret oprensning af stamcelleafledt retinalt pigmentepitel - Google Patents
MACS-baseret oprensning af stamcelleafledt retinalt pigmentepitel Download PDFInfo
- Publication number
- DK3347457T3 DK3347457T3 DK16775018.1T DK16775018T DK3347457T3 DK 3347457 T3 DK3347457 T3 DK 3347457T3 DK 16775018 T DK16775018 T DK 16775018T DK 3347457 T3 DK3347457 T3 DK 3347457T3
- Authority
- DK
- Denmark
- Prior art keywords
- macs
- stem cell
- retinal pigment
- pigment epithelium
- based purification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Developmental Biology & Embryology (AREA)
- Transplantation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562215272P | 2015-09-08 | 2015-09-08 | |
| PCT/US2016/050554 WO2017044488A1 (en) | 2015-09-08 | 2016-09-07 | Macs-based purification of stem cell-derived retinal pigment epithelium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3347457T3 true DK3347457T3 (da) | 2022-01-17 |
Family
ID=57045392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16775018.1T DK3347457T3 (da) | 2015-09-08 | 2016-09-07 | MACS-baseret oprensning af stamcelleafledt retinalt pigmentepitel |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11162070B2 (enExample) |
| EP (2) | EP4001402A1 (enExample) |
| JP (3) | JP6986016B2 (enExample) |
| KR (2) | KR102899289B1 (enExample) |
| CN (2) | CN108291206B (enExample) |
| AU (1) | AU2016318774B2 (enExample) |
| CA (1) | CA2997763A1 (enExample) |
| DK (1) | DK3347457T3 (enExample) |
| ES (1) | ES2903442T3 (enExample) |
| LT (1) | LT3347457T (enExample) |
| WO (1) | WO2017044488A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| ES2722207T3 (es) | 2011-04-29 | 2019-08-08 | Univ Southern California | Procedimientos para la crioconservación de células epiteliales de pigmento retiniano derivadas de citoblastos crecidas sobre un sustrato polimérico |
| TWI810142B (zh) | 2014-10-24 | 2023-08-01 | 日商住友製藥股份有限公司 | 神經組織的製造方法 |
| DK3347456T3 (da) | 2015-09-08 | 2024-02-19 | Us Health | Fremgangsmåde til reproducerbar differentiering af retinale pigmentepitelceller af klinisk kvalitet |
| AU2016318774B2 (en) | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| US10947502B2 (en) | 2015-10-20 | 2021-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
| WO2017123789A1 (en) * | 2016-01-12 | 2017-07-20 | Lonza Walkersville, Inc. | Methods and vectors to produce vector free induced pluripotent stem cells |
| SG11201809201UA (en) * | 2016-04-22 | 2018-11-29 | Sumitomo Dainippon Pharma Co Ltd | Method for producing retinal tissue |
| JP2020501543A (ja) | 2016-12-07 | 2020-01-23 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | 網膜色素上皮移植のためのフィブリン支持体を用いた方法及び材料 |
| SG11201909331UA (en) | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Antigen-specific immune effector cells |
| KR102624998B1 (ko) * | 2017-06-05 | 2024-01-12 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 줄기 세포의 배양, 증식 및 분화를 위한 방법 및 물질 |
| JP7376092B2 (ja) * | 2017-06-15 | 2023-11-08 | ザ ユニバーシティ オブ ノース テキサス ヘルス サイエンス センター アット フォート ワース | 網膜細胞への線維芽細胞の再プログラミング方法 |
| WO2019099552A1 (en) * | 2017-11-14 | 2019-05-23 | The J. David Gladstone Institutes | Methods of generating retinal pigment epithelium (rpe) |
| JP2021521792A (ja) * | 2018-04-20 | 2021-08-30 | フジフィルム セルラー ダイナミクス，インコーポレイテッド | 眼球細胞の分化方法及びその使用 |
| WO2019213366A1 (en) * | 2018-05-02 | 2019-11-07 | The Trustees Of Columbia University In The City Of New York | Methods to induce terminal differentiation in stem cells by interfering with dna replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof |
| PT4234024T (pt) * | 2018-06-20 | 2026-01-21 | Biolamina Ab | Métodos e composições para produzir células do epitélio do pigmento da retina |
| CA3110745A1 (en) | 2018-09-07 | 2020-03-12 | University Of Southern California | Cryopreservation of cell-seeded substrates and related methods |
| SG11202104401RA (en) * | 2018-11-19 | 2021-05-28 | The United States Of America As Represented By The Secretary | Biodegradable tissue replacement implant and its use |
| AU2020364157A1 (en) | 2019-10-09 | 2022-04-14 | Bluerock Therapeutics Lp | Cells with sustained transgene expression |
| TW202130806A (zh) | 2019-10-30 | 2021-08-16 | 安斯泰來再生醫藥協會 | 用於產生視網膜色素上皮細胞之方法 |
| US20230201267A1 (en) * | 2020-05-29 | 2023-06-29 | FUJIFILM Cellular Dynamics, Inc. | Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof |
| KR20230159550A (ko) | 2021-03-25 | 2023-11-21 | 블루록 테라퓨틱스 엘피 | 유도 만능 줄기 세포 수득 방법 |
| CA3220602A1 (en) * | 2021-05-28 | 2022-12-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods to generate macular, central and peripheral retinal pigment epithelial cells |
| CN115873797B (zh) * | 2021-09-29 | 2024-08-13 | 北京干细胞与再生医学研究院 | 一种视网膜色素上皮细胞的扩增培养基及培养方法 |
| JP2025508776A (ja) * | 2022-02-22 | 2025-04-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 人工セルトリ細胞およびその人工セルトリ細胞を産生するための方法 |
| KR20250067762A (ko) * | 2022-04-08 | 2025-05-15 | 뉴욕 스템 셀 파운데이션, 인코포레이티드 | iPSC의 생산 방법 |
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| DK3347456T3 (da) | 2015-09-08 | 2024-02-19 | Us Health | Fremgangsmåde til reproducerbar differentiering af retinale pigmentepitelceller af klinisk kvalitet |
| AU2016318774B2 (en) | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| SG11201801770VA (en) | 2015-09-08 | 2018-04-27 | Sumitomo Dainippon Pharma Co Ltd | Method for producing retinal pigment epithelial cells |
| US10947502B2 (en) | 2015-10-20 | 2021-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
-
2016
- 2016-09-07 AU AU2016318774A patent/AU2016318774B2/en active Active
- 2016-09-07 CA CA2997763A patent/CA2997763A1/en active Pending
- 2016-09-07 CN CN201680060869.2A patent/CN108291206B/zh active Active
- 2016-09-07 KR KR1020187009885A patent/KR102899289B1/ko active Active
- 2016-09-07 WO PCT/US2016/050554 patent/WO2017044488A1/en not_active Ceased
- 2016-09-07 LT LTEPPCT/US2016/050554T patent/LT3347457T/lt unknown
- 2016-09-07 US US15/258,744 patent/US11162070B2/en active Active
- 2016-09-07 KR KR1020257040966A patent/KR20260003355A/ko active Pending
- 2016-09-07 JP JP2018531311A patent/JP6986016B2/ja active Active
- 2016-09-07 DK DK16775018.1T patent/DK3347457T3/da active
- 2016-09-07 EP EP21204608.0A patent/EP4001402A1/en active Pending
- 2016-09-07 ES ES16775018T patent/ES2903442T3/es active Active
- 2016-09-07 CN CN202210521542.8A patent/CN114717188B/zh active Active
- 2016-09-07 EP EP16775018.1A patent/EP3347457B1/en active Active
-
2021
- 2021-08-19 JP JP2021133999A patent/JP2021184742A/ja active Pending
- 2021-10-04 US US17/493,533 patent/US12241083B2/en active Active
-
2023
- 2023-08-18 JP JP2023133410A patent/JP2023162277A/ja active Pending
-
2024
- 2024-09-16 US US18/886,115 patent/US20250011714A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20250011714A1 (en) | 2025-01-09 |
| CN108291206A (zh) | 2018-07-17 |
| EP4001402A1 (en) | 2022-05-25 |
| AU2016318774B2 (en) | 2022-08-18 |
| CN114717188B (zh) | 2025-10-28 |
| US11162070B2 (en) | 2021-11-02 |
| EP3347457B1 (en) | 2021-10-27 |
| JP2021184742A (ja) | 2021-12-09 |
| AU2016318774A1 (en) | 2018-03-08 |
| WO2017044488A1 (en) | 2017-03-16 |
| US20170067017A1 (en) | 2017-03-09 |
| EP3347457A1 (en) | 2018-07-18 |
| CA2997763A1 (en) | 2017-03-16 |
| ES2903442T3 (es) | 2022-04-01 |
| KR20180042436A (ko) | 2018-04-25 |
| KR102899289B1 (ko) | 2025-12-15 |
| CN114717188A (zh) | 2022-07-08 |
| JP2023162277A (ja) | 2023-11-08 |
| JP2018526032A (ja) | 2018-09-13 |
| LT3347457T (lt) | 2022-02-10 |
| US12241083B2 (en) | 2025-03-04 |
| JP6986016B2 (ja) | 2021-12-22 |
| US20220033770A1 (en) | 2022-02-03 |
| KR20260003355A (ko) | 2026-01-06 |
| CN108291206B (zh) | 2022-07-08 |
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