KR102833674B1 - 벤젠술폰아미드 화합물 및 치료제로서의 그의 용도 - Google Patents

벤젠술폰아미드 화합물 및 치료제로서의 그의 용도 Download PDF

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KR102833674B1
KR102833674B1 KR1020217000602A KR20217000602A KR102833674B1 KR 102833674 B1 KR102833674 B1 KR 102833674B1 KR 1020217000602 A KR1020217000602 A KR 1020217000602A KR 20217000602 A KR20217000602 A KR 20217000602A KR 102833674 B1 KR102833674 B1 KR 102833674B1
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compound
methyl
amino
azabicyclo
heptan
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KR20210019507A (ko
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틸로 포켄
크리스틴 니콜 버포드
베르너 알렉산더 로프스트랜드
마이클 스콧 윌슨
알라 유레브나 제노바
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제논 파마슈티칼스 인크.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/50—Nitrogen atoms bound to hetero atoms
    • C07D277/52—Nitrogen atoms bound to hetero atoms to sulfur atoms, e.g. sulfonamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020217000602A 2018-06-13 2019-06-13 벤젠술폰아미드 화합물 및 치료제로서의 그의 용도 Active KR102833674B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862684436P 2018-06-13 2018-06-13
US62/684,436 2018-06-13
PCT/US2019/037011 WO2019241533A1 (en) 2018-06-13 2019-06-13 Benzenesulfonamide compounds and their use as therapeutic agents

Publications (2)

Publication Number Publication Date
KR20210019507A KR20210019507A (ko) 2021-02-22
KR102833674B1 true KR102833674B1 (ko) 2025-07-14

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US (2) US10745392B2 (enExample)
EP (1) EP3807281A1 (enExample)
JP (3) JP7371029B2 (enExample)
KR (1) KR102833674B1 (enExample)
CN (1) CN112262142B (enExample)
AU (1) AU2019285184B2 (enExample)
BR (1) BR112020024729A2 (enExample)
CA (1) CA3103600A1 (enExample)
CL (1) CL2020003197A1 (enExample)
CR (1) CR20200613A (enExample)
EA (1) EA202092719A1 (enExample)
EC (1) ECSP20079861A (enExample)
IL (1) IL278949B2 (enExample)
JO (1) JOP20200304A1 (enExample)
MA (1) MA52888A (enExample)
MX (1) MX2020013317A (enExample)
NI (1) NI202000098A (enExample)
PE (1) PE20211389A1 (enExample)
PH (1) PH12020552111A1 (enExample)
SA (1) SA520420768B1 (enExample)
SG (1) SG11202011862PA (enExample)
UA (1) UA127024C2 (enExample)
WO (1) WO2019241533A1 (enExample)

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CN117510431A (zh) * 2023-11-08 2024-02-06 浙江雅辰药物科技股份有限公司 一种异噻唑-3-酮及其衍生物、合成方法

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Also Published As

Publication number Publication date
WO2019241533A1 (en) 2019-12-19
JP2021528387A (ja) 2021-10-21
CN112262142B (zh) 2023-11-14
JP2025128218A (ja) 2025-09-02
EP3807281A1 (en) 2021-04-21
JP2023138672A (ja) 2023-10-02
JOP20200304A1 (ar) 2020-11-25
PH12020552111A1 (en) 2021-08-02
BR112020024729A2 (pt) 2021-03-23
US20200361927A1 (en) 2020-11-19
AU2019285184A1 (en) 2021-01-28
JP7371029B2 (ja) 2023-10-30
US10745392B2 (en) 2020-08-18
MA52888A (fr) 2021-04-21
MX2020013317A (es) 2021-04-13
AU2019285184B2 (en) 2023-11-16
US11325902B2 (en) 2022-05-10
IL278949B1 (en) 2024-04-01
EA202092719A1 (ru) 2021-03-16
CA3103600A1 (en) 2019-12-19
CL2020003197A1 (es) 2021-04-30
NI202000098A (es) 2021-05-28
US20190382398A1 (en) 2019-12-19
PE20211389A1 (es) 2021-07-27
CN112262142A (zh) 2021-01-22
KR20210019507A (ko) 2021-02-22
CR20200613A (es) 2021-06-10
IL278949A (en) 2021-01-31
SA520420768B1 (ar) 2022-08-30
UA127024C2 (uk) 2023-03-15
SG11202011862PA (en) 2020-12-30
IL278949B2 (en) 2024-08-01
ECSP20079861A (es) 2021-03-31

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