KR102706743B1 - 인간 il-15에 특이적으로 결합하는 항체 및 이의 용도 - Google Patents
인간 il-15에 특이적으로 결합하는 항체 및 이의 용도 Download PDFInfo
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- KR102706743B1 KR102706743B1 KR1020237031493A KR20237031493A KR102706743B1 KR 102706743 B1 KR102706743 B1 KR 102706743B1 KR 1020237031493 A KR1020237031493 A KR 1020237031493A KR 20237031493 A KR20237031493 A KR 20237031493A KR 102706743 B1 KR102706743 B1 KR 102706743B1
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
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- G—PHYSICS
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5443—IL-15
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| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| JP6982362B2 (ja) | 2015-09-18 | 2021-12-17 | ツイスト バイオサイエンス コーポレーション | オリゴ核酸変異体ライブラリーとその合成 |
| KR20250053972A (ko) | 2015-09-22 | 2025-04-22 | 트위스트 바이오사이언스 코포레이션 | 핵산 합성을 위한 가요성 기판 |
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| PT3558369T (pt) | 2016-12-21 | 2025-05-06 | Cephalon Llc | Anticorpos que se ligam especificamente à il-15 humana e suas utilizações |
| WO2018156792A1 (en) | 2017-02-22 | 2018-08-30 | Twist Bioscience Corporation | Nucleic acid based data storage |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| SG11201912057RA (en) | 2017-06-12 | 2020-01-30 | Twist Bioscience Corp | Methods for seamless nucleic acid assembly |
| JP2020536504A (ja) | 2017-09-11 | 2020-12-17 | ツイスト バイオサイエンス コーポレーション | Ｇｐｃｒ結合タンパク質およびその合成 |
| GB2583590A (en) | 2017-10-20 | 2020-11-04 | Twist Bioscience Corp | Heated nanowells for polynucleotide synthesis |
| GB2585506A (en) | 2018-01-04 | 2021-01-13 | Twist Bioscience Corp | DNA-based digital information storage |
| CN118957038A (zh) | 2018-05-18 | 2024-11-15 | 特韦斯特生物科学公司 | 用于核酸杂交的多核苷酸、试剂和方法 |
| US12459980B2 (en) | 2018-07-25 | 2025-11-04 | AskGene Pharma, Inc. | IL-21 prodrugs and methods of use thereof |
| WO2020138073A1 (ja) | 2018-12-25 | 2020-07-02 | Ntn株式会社 | 流量制御バルブ用シールおよび流量制御バルブ装置 |
| CN113692409B (zh) | 2018-12-26 | 2025-01-10 | 特韦斯特生物科学公司 | 高度准确的从头多核苷酸合成 |
| JP2022522668A (ja) | 2019-02-26 | 2022-04-20 | ツイスト バイオサイエンス コーポレーション | 抗体を最適化するための変異体核酸ライブラリ |
| AU2020229349A1 (en) | 2019-02-26 | 2021-10-14 | Twist Bioscience Corporation | Variant nucleic acid libraries for GLP1 receptor |
| AU2020291012B2 (en) | 2019-06-12 | 2025-09-25 | AskGene Pharma, Inc. | Novel IL-15 prodrugs and methods of use thereof |
| EP3987019A4 (en) | 2019-06-21 | 2023-04-19 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| CN115023440B (zh) | 2019-09-23 | 2025-09-12 | 特韦斯特生物科学公司 | 结合CD3ε的抗体 |
| EP4034566A4 (en) | 2019-09-23 | 2024-01-24 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID BANKS FOR CRTH2 |
| BR112022011235A2 (pt) * | 2019-12-09 | 2022-12-13 | Twist Bioscience Corp | Bibliotecas de variantes de ácido nucleico para receptores de adenosina |
| JP2023545821A (ja) * | 2020-10-16 | 2023-10-31 | ジェネンテック， インコーポレイテッド | 抗ｉＣａｓｐａｓｅ切断基質抗体および使用方法 |
| EP4281112A4 (en) | 2021-01-21 | 2025-01-15 | Twist Bioscience Corporation | METHODS AND COMPOSITIONS RELATING TO ADENOSINE RECEPTORS |
| CN116655771A (zh) * | 2021-05-28 | 2023-08-29 | 苏州复融生物技术有限公司 | 一种新型白介素15突变体多肽的开发及其应用 |
| JP2025525860A (ja) | 2022-08-04 | 2025-08-07 | ノバルティス ファーマ アーゲー | アトピー性皮膚炎の治療に有用なｉｌ－１５阻害剤 |
| CN118894934A (zh) * | 2023-05-05 | 2024-11-05 | 北京智仁美博生物科技有限公司 | 抗人il-15的抗体及其用途 |
| CN117209605B (zh) * | 2023-11-09 | 2024-01-30 | 北京百普赛斯生物科技股份有限公司 | 特异性结合il-15的抗体及其应用 |
| WO2025227052A1 (en) * | 2024-04-26 | 2025-10-30 | Cephalon Llc | Doses and formulations of anti-il-15 antibody for the treatment of immune diseases |
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| MA46534A (fr) | 2016-10-14 | 2019-08-21 | Xencor Inc | Protéines de fusion fc hétérodimères il15/il15r |
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