KR102643557B1 - 대상 분자의 생성을 위한 유전자 최적화 미생물 - Google Patents

대상 분자의 생성을 위한 유전자 최적화 미생물 Download PDF

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KR102643557B1
KR102643557B1 KR1020197024086A KR20197024086A KR102643557B1 KR 102643557 B1 KR102643557 B1 KR 102643557B1 KR 1020197024086 A KR1020197024086 A KR 1020197024086A KR 20197024086 A KR20197024086 A KR 20197024086A KR 102643557 B1 KR102643557 B1 KR 102643557B1
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microorganism
genetically modified
gene
expression
molecule
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KR20190115447A (ko
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세드릭 보이스아트
니콜라스 모린
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에펜 유럽
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12N9/14—Hydrolases (3)
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    • C12Y101/01044—Phosphogluconate dehydrogenase (decarboxylating) (1.1.1.44)
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    • C12Y101/01049—Glucose-6-phosphate dehydrogenase (1.1.1.49)
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    • C12Y102/01012—Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (1.2.1.12)
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01019—Phosphoribulokinase (2.7.1.19)
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    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02003—Phosphoglycerate kinase (2.7.2.3)
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    • C12Y301/01031—6-Phosphogluconolactonase (3.1.1.31)
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    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01039—Ribulose-bisphosphate carboxylase (4.1.1.39)

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  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020197024086A 2017-01-27 2018-01-26 대상 분자의 생성을 위한 유전자 최적화 미생물 Active KR102643557B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1750694A FR3062394B1 (fr) 2017-01-27 2017-01-27 Microorganisme genetiquement optimise pour la production de molecules d'interet
FR1750694 2017-01-27
PCT/EP2018/052005 WO2018138289A1 (fr) 2017-01-27 2018-01-26 Microorganisme génétiquement optimisé pour la production de molécules d'intérêt

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KR20190115447A KR20190115447A (ko) 2019-10-11
KR102643557B1 true KR102643557B1 (ko) 2024-03-07

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US (2) US20200277592A1 (enExample)
EP (1) EP3574083A1 (enExample)
JP (2) JP7240329B2 (enExample)
KR (1) KR102643557B1 (enExample)
CN (1) CN110678541A (enExample)
BR (1) BR112019015458A2 (enExample)
FR (1) FR3062394B1 (enExample)
WO (1) WO2018138289A1 (enExample)

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DK2958986T3 (da) * 2013-02-22 2022-11-28 Dsm Ip Assets Bv Rekombinant mikroorganisme til anvendelse i en fremgangsmåde med forøget produktudbytte
CN109312296B (zh) * 2016-06-14 2023-05-05 帝斯曼知识产权资产管理有限公司 重组酵母细胞
US20220228165A1 (en) * 2019-05-10 2022-07-21 Cncure Biotech Inc. DNA Construct for Diagnosing and Treating Cancer
JP6917434B2 (ja) * 2019-10-25 2021-08-11 長瀬産業株式会社 好気性菌の代謝酵素破壊株およびその培養法
CN112852664B (zh) * 2021-01-14 2022-07-15 西华大学 一种酿酒酵母以及提高酿酒酵母产γ-氨基丁酸的方法
CN112941061B (zh) * 2021-03-19 2021-09-07 中国农业大学 一种Tk-Rubisco突变体、线性组装材料及其制备方法和应用
CN114164237B (zh) * 2021-11-04 2023-03-17 山东阜丰发酵有限公司 一种生产琥珀酸的方法
CN114181879B (zh) * 2021-12-09 2022-11-22 中国科学院深圳先进技术研究院 具有自养能力的底盘细胞及其构建方法和应用
CN115851779B (zh) * 2022-10-29 2024-03-26 昆明理工大学 一种葡萄糖-6-磷酸脱氢酶基因RkZWF1及其应用
CN117210446A (zh) * 2023-03-21 2023-12-12 北京蓝晶微生物科技有限公司 一种重建卡尔文循环提高异养微生物代谢产物产量的方法
CN120384059B (zh) * 2025-06-27 2025-09-26 南京大学 葡萄糖-6-磷酸脱氢酶突变体、生物材料、催化剂及应用

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JP2002529079A (ja) 1998-11-10 2002-09-10 マキシジェン， インコーポレイテッド 改変されたリブロース１，５−ビスホスフェートカルボキシラーゼ／オキシゲナーゼ
WO2009036095A1 (en) 2007-09-10 2009-03-19 Joule Biotechnologies, Inc. Engineered light-harvesting organisms
WO2015177800A2 (en) * 2014-05-22 2015-11-26 Yeda Research And Development Co. Ltd. Recombinant microorganisms capable of carbon fixation

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US7826975B2 (en) 2002-07-10 2010-11-02 The Penn State Research Foundation Method for redesign of microbial production systems
FR3016371B1 (fr) 2014-01-16 2018-02-02 Institut National De La Recherche Agronomique Levures modifiees pour utiliser le dioxyde de carbone

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
JP2002529079A (ja) 1998-11-10 2002-09-10 マキシジェン， インコーポレイテッド 改変されたリブロース１，５−ビスホスフェートカルボキシラーゼ／オキシゲナーゼ
WO2009036095A1 (en) 2007-09-10 2009-03-19 Joule Biotechnologies, Inc. Engineered light-harvesting organisms
WO2015177800A2 (en) * 2014-05-22 2015-11-26 Yeda Research And Development Co. Ltd. Recombinant microorganisms capable of carbon fixation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Oliver Mueller-Cajar 등, Photosynthesis Research, 제98권, 페이지 667-675 (2008)

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Publication number Publication date
US12018300B2 (en) 2024-06-25
FR3062394A1 (fr) 2018-08-03
US20200277592A1 (en) 2020-09-03
EP3574083A1 (fr) 2019-12-04
US20220348897A1 (en) 2022-11-03
KR20190115447A (ko) 2019-10-11
CN110678541A (zh) 2020-01-10
FR3062394B1 (fr) 2021-04-16
JP2023011947A (ja) 2023-01-24
JP7240329B2 (ja) 2023-03-15
JP2020506723A (ja) 2020-03-05
BR112019015458A2 (pt) 2020-03-31
WO2018138289A1 (fr) 2018-08-02

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