KR102617137B1 - 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물 - Google Patents

히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물 Download PDF

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KR102617137B1
KR102617137B1 KR1020227041766A KR20227041766A KR102617137B1 KR 102617137 B1 KR102617137 B1 KR 102617137B1 KR 1020227041766 A KR1020227041766 A KR 1020227041766A KR 20227041766 A KR20227041766 A KR 20227041766A KR 102617137 B1 KR102617137 B1 KR 102617137B1
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이 장
소고 마토바
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칠드런'즈 메디컬 센터 코포레이션
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12Y201/00—Transferases transferring one-carbon groups (2.1)
    • C12Y201/01—Methyltransferases (2.1.1)
    • C12Y201/01043—Histone-lysine N-methyltransferase (2.1.1.43)
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    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

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KR1020227041766A 2014-09-15 2015-09-15 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물 Active KR102617137B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462050308P 2014-09-15 2014-09-15
US62/050,308 2014-09-15
US201462053514P 2014-09-22 2014-09-22
US62/053,514 2014-09-22
KR1020177010127A KR102473092B1 (ko) 2014-09-15 2015-09-15 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물
PCT/US2015/050178 WO2016044271A2 (en) 2014-09-15 2015-09-15 Methods and compositions to increase somatic cell nuclear transfer (scnt) efficiency by removing histone h3-lysine trimethylation

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KR1020177010127A Division KR102473092B1 (ko) 2014-09-15 2015-09-15 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물

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KR20220165807A KR20220165807A (ko) 2022-12-15
KR102617137B1 true KR102617137B1 (ko) 2023-12-27

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KR1020177010127A Active KR102473092B1 (ko) 2014-09-15 2015-09-15 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물

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US (3) US11390885B2 (enExample)
EP (1) EP3194581A4 (enExample)
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WO (1) WO2016044271A2 (enExample)

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KR102617137B1 (ko) 2014-09-15 2023-12-27 칠드런'즈 메디컬 센터 코포레이션 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물
CN106591374B (zh) * 2016-12-30 2019-08-09 中国农业科学院北京畜牧兽医研究所 一种提高猪体细胞核移植胚胎发育效率的方法
CN106676136B (zh) * 2016-12-30 2019-11-29 中国农业科学院北京畜牧兽医研究所 一种提高猪体细胞核移植效率的方法
CN107299113A (zh) * 2017-06-12 2017-10-27 内蒙古大学 H3K27me3及其去甲基化酶KDM6A/B在小鼠核移植重构胚中的应用方法
CN108285906B (zh) * 2017-12-29 2021-07-09 温氏食品集团股份有限公司 一种定点整合外源dna转基因猪的构建方法
CN108624621B (zh) * 2018-01-17 2019-04-12 中国科学院上海生命科学研究院 非人灵长类的体细胞克隆动物的制备方法
KR102204413B1 (ko) * 2018-01-23 2021-01-18 차의과학대학교 산학협력단 Rad51 활성화제를 포함하는, 배아 발달용 조성물 및 이를 이용하여 배아 발달률을 향상시키는 방법
WO2019147026A1 (ko) * 2018-01-23 2019-08-01 차의과학대학교 산학협력단 멜라토닌을 포함하는, 배아 발달용 조성물 및 이를 이용하여 배아 발달의 효율을 향상시키는 방법
US20210155959A1 (en) * 2018-04-06 2021-05-27 Children's Medical Center Corporation Compositions and methods for somatic cell reprogramming and modulating imprinting
CN110547291A (zh) * 2019-09-27 2019-12-10 安徽医科大学 一种高效抗氧化的人卵母细胞冷冻保护剂
CN111466367B (zh) * 2020-02-17 2022-03-01 天津大学 用于保存细胞的组合物
KR102520268B1 (ko) * 2020-12-04 2023-04-12 대한민국 microRNA-148a 직접 주입을 통한 돼지 체세포 핵치환란의 발달율 향상 방법
CN113186152B (zh) * 2021-05-19 2023-05-26 南方医科大学 Dna甲基转移酶抑制剂在提高动物圆形精子注射胚胎发育效率中的应用
CN119162252B (zh) * 2024-11-20 2025-05-02 中国科学院昆明动物研究所 一种通过重构核移植囊胚提高克隆小鼠出生率的方法

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