KR102615210B1 - 난소암의 치료에 사용되는 티노스타무스틴 - Google Patents

난소암의 치료에 사용되는 티노스타무스틴 Download PDF

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Publication number
KR102615210B1
KR102615210B1 KR1020197037078A KR20197037078A KR102615210B1 KR 102615210 B1 KR102615210 B1 KR 102615210B1 KR 1020197037078 A KR1020197037078 A KR 1020197037078A KR 20197037078 A KR20197037078 A KR 20197037078A KR 102615210 B1 KR102615210 B1 KR 102615210B1
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South Korea
Prior art keywords
pharmaceutically acceptable
tinostamustine
pharmaceutical composition
ovarian cancer
acceptable salt
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Korean (ko)
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KR20200014790A (ko
Inventor
토마스 요르크 메를링
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유로-셀띠끄 소시에떼 아노님
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020197037078A 2017-06-13 2018-06-13 난소암의 치료에 사용되는 티노스타무스틴 Active KR102615210B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1709405.3 2017-06-13
GBGB1709405.3A GB201709405D0 (en) 2017-06-13 2017-06-13 Compounds for treating ovarian cancer
PCT/EP2018/065669 WO2018229134A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in treating ovarian cancer

Publications (2)

Publication Number Publication Date
KR20200014790A KR20200014790A (ko) 2020-02-11
KR102615210B1 true KR102615210B1 (ko) 2023-12-18

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197037078A Active KR102615210B1 (ko) 2017-06-13 2018-06-13 난소암의 치료에 사용되는 티노스타무스틴

Country Status (14)

Country Link
US (2) US11896583B2 (https=)
EP (2) EP3960169A1 (https=)
JP (1) JP2020523356A (https=)
KR (1) KR102615210B1 (https=)
AR (1) AR112102A1 (https=)
AU (1) AU2018285823B2 (https=)
BR (1) BR112019026486A2 (https=)
CA (1) CA3067052A1 (https=)
ES (1) ES2899636T3 (https=)
GB (1) GB201709405D0 (https=)
IL (1) IL271019A (https=)
MX (1) MX388722B (https=)
TW (1) TW201919617A (https=)
WO (1) WO2018229134A1 (https=)

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GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
AU2016426574B2 (en) 2016-10-11 2023-07-13 Euro-Celtique S.A. Hodgkin lymphoma therapy
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
CN113365624A (zh) * 2018-12-18 2021-09-07 萌蒂制药国际有限公司 用于治疗淋巴瘤或t-细胞恶性疾病的化合物
CN115253066A (zh) * 2022-07-21 2022-11-01 湖南安泰康成生物科技有限公司 卵巢癌治疗系统以及卵巢癌治疗的交变电场发生装置
CN117017962A (zh) * 2023-08-23 2023-11-10 复旦大学附属肿瘤医院 一种hdaci抑制剂在制备治疗卵巢癌药物中的用途

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Also Published As

Publication number Publication date
CA3067052A1 (en) 2018-12-20
AU2018285823A1 (en) 2019-12-19
MX388722B (es) 2025-03-20
EP3960169A1 (en) 2022-03-02
JP2020523356A (ja) 2020-08-06
GB201709405D0 (en) 2017-07-26
US11896583B2 (en) 2024-02-13
US20200261423A1 (en) 2020-08-20
ES2899636T3 (es) 2022-03-14
MX2019015207A (es) 2021-12-10
WO2018229134A1 (en) 2018-12-20
TW201919617A (zh) 2019-06-01
AR112102A1 (es) 2019-09-18
EP3638233A1 (en) 2020-04-22
US20240261265A1 (en) 2024-08-08
EP3638233B1 (en) 2021-09-22
AU2018285823B2 (en) 2024-05-30
IL271019A (en) 2020-01-30
KR20200014790A (ko) 2020-02-11
BR112019026486A2 (pt) 2020-07-14

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