KR102555177B1 - 항균 펩타이드 및 이의 사용 방법 - Google Patents

항균 펩타이드 및 이의 사용 방법 Download PDF

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KR102555177B1
KR102555177B1 KR1020207015602A KR20207015602A KR102555177B1 KR 102555177 B1 KR102555177 B1 KR 102555177B1 KR 1020207015602 A KR1020207015602 A KR 1020207015602A KR 20207015602 A KR20207015602 A KR 20207015602A KR 102555177 B1 KR102555177 B1 KR 102555177B1
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KR20200074212A (ko
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마이클 쿤
리처드 앤드루 에윈
데렉 제임스 시한
에릭 바이마
크리스토퍼 에이 주크
힐러리 펠프스
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조에티스 서비시즈 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8281—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for bacterial resistance

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
KR1020207015602A 2017-12-07 2018-12-05 항균 펩타이드 및 이의 사용 방법 Active KR102555177B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237023202A KR102713813B1 (ko) 2017-12-07 2018-12-05 항균 펩타이드 및 이의 사용 방법

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762595725P 2017-12-07 2017-12-07
US62/595,725 2017-12-07
PCT/US2018/064029 WO2019113181A1 (en) 2017-12-07 2018-12-05 Antimicrobial peptides and methods of using same

Related Child Applications (1)

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KR1020237023202A Division KR102713813B1 (ko) 2017-12-07 2018-12-05 항균 펩타이드 및 이의 사용 방법

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KR20200074212A KR20200074212A (ko) 2020-06-24
KR102555177B1 true KR102555177B1 (ko) 2023-07-12

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KR1020237023202A Active KR102713813B1 (ko) 2017-12-07 2018-12-05 항균 펩타이드 및 이의 사용 방법
KR1020247032634A Pending KR20240151857A (ko) 2017-12-07 2018-12-05 항균 펩타이드 및 이의 사용 방법

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KR1020247032634A Pending KR20240151857A (ko) 2017-12-07 2018-12-05 항균 펩타이드 및 이의 사용 방법

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US (3) US11352396B2 (https=)
EP (2) EP4656726A3 (https=)
JP (1) JP7381465B2 (https=)
KR (3) KR102555177B1 (https=)
CN (1) CN111479824A (https=)
AR (1) AR113618A1 (https=)
AU (3) AU2018378035B2 (https=)
BR (1) BR112020009973A2 (https=)
CA (1) CA3082491A1 (https=)
CL (1) CL2020001464A1 (https=)
CO (1) CO2020006907A2 (https=)
DK (1) DK3720875T3 (https=)
ES (1) ES3041688T3 (https=)
FI (1) FI3720875T3 (https=)
HU (1) HUE072916T2 (https=)
IL (2) IL275074B2 (https=)
LT (1) LT3720875T (https=)
MX (1) MX2020005920A (https=)
NZ (1) NZ764838A (https=)
PH (1) PH12020550942A1 (https=)
PL (1) PL3720875T3 (https=)
PT (1) PT3720875T (https=)
SG (1) SG11202004661QA (https=)
SI (1) SI3720875T1 (https=)
TW (2) TWI786887B (https=)
WO (1) WO2019113181A1 (https=)
ZA (1) ZA202003387B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220307048A1 (en) * 2021-03-23 2022-09-29 Genvor Inc. Antimicrobial peptides
CN113185576B (zh) * 2021-04-09 2023-05-30 倪京满 一类具有RRRF转角的β-发卡型低毒广谱抗菌肽及其应用
US20250042946A1 (en) 2021-12-08 2025-02-06 Oakgrove Bio Llc Biological Production of Histidine-Rich Peptides
EP4198045A1 (en) * 2021-12-16 2023-06-21 Université de Lille Antimicrobial peptides, variants and chemical analogues thereof and their uses
WO2024003890A1 (en) * 2022-06-29 2024-01-04 Omnix Medical Ltd. Novel peptide for treating an infectious disease or condition
CN120309697B (zh) * 2025-06-13 2025-09-02 四川大学 一种用于抗革兰氏阴性菌的多肽药物及应用
CN121378418B (zh) * 2025-12-26 2026-04-03 四川大学 一组针对革兰氏阴性菌的抗菌多肽

Citations (7)

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WO2010009614A1 (zh) 2008-07-22 2010-01-28 北京中农颖泰生物技术有限公司 抗菌肽cad在枯草杆菌中的分泌表达及重组枯草杆菌表达系统
CN101698682A (zh) 2009-10-26 2010-04-28 陕西省微生物研究所 一种基于抗菌肽的双功能融合蛋白及其制备方法和用途
CN101817883A (zh) 2010-03-12 2010-09-01 广东药学院 一种家蝇天蚕素-人溶菌酶融合蛋白及其制备方法和应用
CN101851620A (zh) 2010-04-21 2010-10-06 吉林农业大学 利用食药用菌生产FGFs的方法
CN103975064A (zh) 2011-07-13 2014-08-06 索拉维斯特生物能源公司 经修饰的天蚕素用于治疗内寄生感染和细菌感染的方法和用途
CN104177502A (zh) 2014-08-21 2014-12-03 天津兰瑞生物技术有限公司 一种鲎素肽-抗体融合蛋白及制备方法
CN104988170A (zh) * 2015-08-01 2015-10-21 吉林农业大学 一种融合抗菌肽及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1323166C (zh) * 2003-09-18 2007-06-27 中国农业科学院饲料研究所 一种鲎素的基因及表达其的方法

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010009614A1 (zh) 2008-07-22 2010-01-28 北京中农颖泰生物技术有限公司 抗菌肽cad在枯草杆菌中的分泌表达及重组枯草杆菌表达系统
CN101698682A (zh) 2009-10-26 2010-04-28 陕西省微生物研究所 一种基于抗菌肽的双功能融合蛋白及其制备方法和用途
CN101817883A (zh) 2010-03-12 2010-09-01 广东药学院 一种家蝇天蚕素-人溶菌酶融合蛋白及其制备方法和应用
CN101851620A (zh) 2010-04-21 2010-10-06 吉林农业大学 利用食药用菌生产FGFs的方法
CN103975064A (zh) 2011-07-13 2014-08-06 索拉维斯特生物能源公司 经修饰的天蚕素用于治疗内寄生感染和细菌感染的方法和用途
CN104177502A (zh) 2014-08-21 2014-12-03 天津兰瑞生物技术有限公司 一种鲎素肽-抗体融合蛋白及制备方法
WO2016026354A1 (zh) * 2014-08-21 2016-02-25 天津兰瑞生物技术有限公司 一种鲎素肽-抗体融合蛋白及制备方法
CN104988170A (zh) * 2015-08-01 2015-10-21 吉林农业大学 一种融合抗菌肽及其制备方法和应用

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TWI746908B (zh) 2021-11-21
PH12020550942A1 (en) 2021-05-10
US20200385429A1 (en) 2020-12-10
ES3041688T3 (en) 2025-11-13
US20250074947A1 (en) 2025-03-06
EP3720875A1 (en) 2020-10-14
BR112020009973A2 (pt) 2020-11-03
CL2020001464A1 (es) 2020-11-06
PT3720875T (pt) 2025-09-18
SI3720875T1 (sl) 2025-11-28
TW202116348A (zh) 2021-05-01
KR20240151857A (ko) 2024-10-18
CO2020006907A2 (es) 2020-06-19
EP4656726A2 (en) 2025-12-03
AU2023229465B2 (en) 2024-06-13
TW201924712A (zh) 2019-07-01
FI3720875T3 (fi) 2025-09-12
HUE072916T2 (hu) 2025-12-28
US11352396B2 (en) 2022-06-07
NZ764838A (en) 2023-07-28
JP2021505624A (ja) 2021-02-18
CN111479824A (zh) 2020-07-31
AU2018378035B2 (en) 2023-06-15
IL275074A (en) 2020-07-30
TWI786887B (zh) 2022-12-11
TW202204376A (zh) 2022-02-01
ZA202003387B (en) 2023-01-25
CA3082491A1 (en) 2019-06-13
AU2024219645A1 (en) 2024-10-03
PL3720875T3 (pl) 2025-10-20
AR113618A1 (es) 2020-05-20
EP3720875B1 (en) 2025-07-16
RU2020118460A (ru) 2022-01-10
IL312730A (en) 2024-07-01
AU2023229465A1 (en) 2023-09-28
JP7381465B2 (ja) 2023-11-15
RU2020118460A3 (https=) 2022-01-10
KR20230110822A (ko) 2023-07-25
KR102713813B1 (ko) 2024-10-11
IL275074B1 (en) 2024-06-01
US20230077604A1 (en) 2023-03-16
LT3720875T (lt) 2025-08-25
AU2018378035A1 (en) 2020-05-28
SG11202004661QA (en) 2020-06-29
WO2019113181A1 (en) 2019-06-13
MX2020005920A (es) 2020-08-20
DK3720875T3 (da) 2025-09-01
US12054518B2 (en) 2024-08-06
KR20200074212A (ko) 2020-06-24
IL275074B2 (en) 2024-10-01
EP4656726A3 (en) 2025-12-31

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