KR102513343B1 - sGC 자극제의 인 전구약물 - Google Patents

sGC 자극제의 인 전구약물 Download PDF

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KR102513343B1
KR102513343B1 KR1020197003458A KR20197003458A KR102513343B1 KR 102513343 B1 KR102513343 B1 KR 102513343B1 KR 1020197003458 A KR1020197003458 A KR 1020197003458A KR 20197003458 A KR20197003458 A KR 20197003458A KR 102513343 B1 KR102513343 B1 KR 102513343B1
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disease
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compound
pulmonary
hypertension
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KR20190026841A (ko
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제임즈 에드워드 쉐펙
폴 앨런 레노위
아라 머메리언
티모시 클라우드 바든
글렌 로버트 레니
라제쉬 알. 아이옌가
타카시 나카이
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사이클리온 테라퓨틱스, 인크.
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    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
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    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
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KR1020197003458A 2016-07-07 2017-07-06 sGC 자극제의 인 전구약물 Active KR102513343B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662359419P 2016-07-07 2016-07-07
US62/359,419 2016-07-07
PCT/US2017/040809 WO2018009596A1 (en) 2016-07-07 2017-07-06 Phosphorus prodrugs of sgc stimulators

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Publication Number Publication Date
KR20190026841A KR20190026841A (ko) 2019-03-13
KR102513343B1 true KR102513343B1 (ko) 2023-03-22

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US (4) US10927136B2 (enExample)
EP (1) EP3481837B1 (enExample)
JP (2) JP7016853B2 (enExample)
KR (1) KR102513343B1 (enExample)
CN (2) CN109476686B (enExample)
AU (2) AU2017291826B2 (enExample)
BR (1) BR112019000290B1 (enExample)
CA (1) CA3029374A1 (enExample)
EA (1) EA039683B1 (enExample)
IL (1) IL263993B2 (enExample)
MA (1) MA45592A (enExample)
MX (2) MX391896B (enExample)
WO (1) WO2018009596A1 (enExample)

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Publication number Priority date Publication date Assignee Title
CN109476686B (zh) * 2016-07-07 2022-01-18 赛克里翁治疗有限公司 sGC刺激剂的磷前药
KR20210031931A (ko) 2018-07-11 2021-03-23 사이클리온 테라퓨틱스, 인크. 미토콘드리아 장애의 치료를 위한 sGC 자극제의 용도
CN114377149B (zh) * 2021-12-14 2023-11-10 西北工业大学 一种Mn基可降解MOF纳米反应器及其制备方法和应用
CN120584098A (zh) * 2022-11-07 2025-09-02 弗吉尼亚联邦大学 用于治疗镰状细胞病的具有直接聚合物失稳效应的苯甲醛化合物
CN116478309B (zh) * 2023-05-19 2024-05-17 青海大学 锁阳精多糖、锁阳多糖化合物及制备方法和应用

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