KR102424644B1 - 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 - Google Patents
1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 Download PDFInfo
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- KR102424644B1 KR102424644B1 KR1020217009475A KR20217009475A KR102424644B1 KR 102424644 B1 KR102424644 B1 KR 102424644B1 KR 1020217009475 A KR1020217009475 A KR 1020217009475A KR 20217009475 A KR20217009475 A KR 20217009475A KR 102424644 B1 KR102424644 B1 KR 102424644B1
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- osteoporosis
- pth
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- administration
- bone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2009-208039 | 2009-09-09 | ||
| JP2009208039 | 2009-09-09 | ||
| KR1020207027785A KR102335703B1 (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| PCT/JP2010/065379 WO2011030774A1 (ja) | 2009-09-09 | 2010-09-08 | 1回当たり100~200単位のpthが週1回投与されることを特徴とする、pth含有骨粗鬆症治療/予防剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207027785A Division KR102335703B1 (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20210040171A KR20210040171A (ko) | 2021-04-12 |
| KR102424644B1 true KR102424644B1 (ko) | 2022-07-25 |
Family
ID=43732444
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197023161A Ceased KR20190095552A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020177019823A Ceased KR20170089017A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR20157003153A Ceased KR20150021590A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020217009475A Active KR102424644B1 (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020127005972A Ceased KR20120067336A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100~200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR20147029471A Withdrawn KR20140130754A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020207027785A Active KR102335703B1 (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020177019824A Ceased KR20170089018A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197023161A Ceased KR20190095552A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020177019823A Ceased KR20170089017A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR20157003153A Ceased KR20150021590A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127005972A Ceased KR20120067336A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100~200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR20147029471A Withdrawn KR20140130754A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020207027785A Active KR102335703B1 (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
| KR1020177019824A Ceased KR20170089018A (ko) | 2009-09-09 | 2010-09-08 | 1회당 100∼200 단위의 pth가 주 1회 투여되는 것을 특징으로 하는, pth 함유 골다공증 치료/예방제 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20120252729A1 (enExample) |
| EP (3) | EP2476429B1 (enExample) |
| JP (13) | JPWO2011030774A1 (enExample) |
| KR (8) | KR20190095552A (enExample) |
| CN (2) | CN102470164B (enExample) |
| AU (1) | AU2010293488B2 (enExample) |
| BR (1) | BR112012003511A2 (enExample) |
| CA (1) | CA2772656A1 (enExample) |
| ES (3) | ES2843649T3 (enExample) |
| IL (1) | IL217854A (enExample) |
| IN (1) | IN2012DN00857A (enExample) |
| MX (1) | MX335951B (enExample) |
| NZ (2) | NZ617397A (enExample) |
| RU (1) | RU2564894C2 (enExample) |
| WO (1) | WO2011030774A1 (enExample) |
| ZA (1) | ZA201201720B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2616004T3 (es) * | 2009-11-18 | 2017-06-09 | Asahi Kasei Pharma Corporation | Agente profiláctico y/o agente terapéutico y/o agente supresor de exacerbación para osteortritis de rodilla humana |
| JP6235219B2 (ja) * | 2013-03-21 | 2017-11-22 | 旭化成ファーマ株式会社 | 脊椎椎体間固定術後の骨癒合促進剤 |
| US10394953B2 (en) | 2015-07-17 | 2019-08-27 | Facebook, Inc. | Meme detection in digital chatter analysis |
| CN110520148A (zh) * | 2017-02-01 | 2019-11-29 | 约翰霍普金斯大学 | 甲状旁腺激素与退行性椎间盘疾病的再生 |
| JP6577683B2 (ja) * | 2017-09-22 | 2019-09-18 | 旭化成ファーマ株式会社 | 安定性に優れるテリパラチド含有液状医薬組成物 |
| JP2019060866A (ja) * | 2017-09-22 | 2019-04-18 | 旭化成ファーマ株式会社 | 液状医薬組成物の体内動態を予測する方法 |
| CA3075984C (en) * | 2017-09-22 | 2024-10-01 | Asahi Kasei Pharma Corp | Teriparatide-containing liquid pharmaceutical composition having excellent pharmacokinetics and/or safety |
| WO2020090174A1 (ja) | 2018-10-29 | 2020-05-07 | 旭化成ファーマ株式会社 | 週2回の頻度でテリパラチド又はその塩を投与することを特徴とする、骨粗鬆症の予防又は治療方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2505812B2 (ja) | 1987-07-10 | 1996-06-12 | 旭化成工業株式会社 | h―PTH(1―34)凍結乾燥組成物 |
| JP2662842B2 (ja) | 1991-12-09 | 1997-10-15 | 旭化成工業株式会社 | パラサイロイドホルモンの安定化組成物 |
| JPH0873376A (ja) * | 1994-09-07 | 1996-03-19 | Asahi Chem Ind Co Ltd | 骨粗鬆症治療薬 |
| SE9702401D0 (sv) * | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
| ZA9811127B (en) * | 1997-12-09 | 2000-07-11 | Lilly Co Eli | Stabilized teriparatide solutions. |
| AR033639A1 (es) | 1998-08-19 | 2004-01-07 | Lilly Co Eli | Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis |
| US6756480B2 (en) * | 2000-04-27 | 2004-06-29 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| WO2002002136A1 (en) | 2000-06-30 | 2002-01-10 | Suntory Limited | Medicinal components comprising human parathyroid hormone and medicinal compositions for nasal administration containing the components |
| JP5042419B2 (ja) * | 2001-08-15 | 2012-10-03 | 旭化成ファーマ株式会社 | 骨形成促進剤および骨形成促進組成物 |
| JP4931306B2 (ja) | 2001-09-27 | 2012-05-16 | 旭化成ファーマ株式会社 | 骨形成を安全に促進させる医薬複合剤 |
| JP2007525472A (ja) * | 2003-07-04 | 2007-09-06 | ニコメド ダンマーク エイピーエス | 経口使用のための副甲状腺ホルモン(pth)含有医薬組成物 |
| US7632813B2 (en) * | 2004-04-26 | 2009-12-15 | Ono Pharmaceutical Co., Ltd. | Bone densifying agent characterized by use of cathepsin K inhibitor with PTH |
| MXPA06012980A (es) * | 2004-05-10 | 2007-06-12 | Nastech Pharm Co | Composiciones y metodos para el suministro mucosal mejorado de la hormona paratiroidea. |
| JP2006241098A (ja) * | 2005-03-04 | 2006-09-14 | Univ Kurume | 骨量減少症の予防または治療薬 |
| ES2427993T3 (es) * | 2006-02-09 | 2013-11-05 | Biomimetic Therapeutics, Llc | Composiciones y métodos para el tratamiento de hueso |
| DE102006043846A1 (de) * | 2006-03-14 | 2007-09-20 | Claudia Zours | Wirbelsäulenorthesen |
| JP2009530307A (ja) * | 2006-03-15 | 2009-08-27 | アルザ コーポレイション | 骨減少症を予防し、または治療するための副甲状腺ホルモン薬の経皮送達のための装置、並びに方法 |
| CN101274961A (zh) * | 2006-03-30 | 2008-10-01 | 天津医科大学 | 重组人甲状旁腺素相关蛋白 |
| CN101125201A (zh) * | 2006-08-17 | 2008-02-20 | 石家庄欧意药业有限公司 | 治疗骨质疏松症或防治由于骨质疏松而导致的骨折的药物组合物及其应用 |
| CN101307105B (zh) * | 2008-04-28 | 2012-08-29 | 中国药科大学 | 一种能串联表达和同步酸水解释放的人甲状旁腺素1-34肽类似物及其制备方法和应用 |
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2010
- 2010-09-08 KR KR1020197023161A patent/KR20190095552A/ko not_active Ceased
- 2010-09-08 WO PCT/JP2010/065379 patent/WO2011030774A1/ja not_active Ceased
- 2010-09-08 KR KR1020177019823A patent/KR20170089017A/ko not_active Ceased
- 2010-09-08 KR KR20157003153A patent/KR20150021590A/ko not_active Ceased
- 2010-09-08 KR KR1020217009475A patent/KR102424644B1/ko active Active
- 2010-09-08 KR KR1020127005972A patent/KR20120067336A/ko not_active Ceased
- 2010-09-08 KR KR20147029471A patent/KR20140130754A/ko not_active Withdrawn
- 2010-09-08 ES ES13181715T patent/ES2843649T3/es active Active
- 2010-09-08 MX MX2012002681A patent/MX335951B/es unknown
- 2010-09-08 US US13/395,000 patent/US20120252729A1/en not_active Abandoned
- 2010-09-08 NZ NZ617397A patent/NZ617397A/en unknown
- 2010-09-08 RU RU2012108635/15A patent/RU2564894C2/ru active
- 2010-09-08 AU AU2010293488A patent/AU2010293488B2/en active Active
- 2010-09-08 JP JP2011530844A patent/JPWO2011030774A1/ja active Pending
- 2010-09-08 ES ES10815369.3T patent/ES2663322T3/es active Active
- 2010-09-08 KR KR1020207027785A patent/KR102335703B1/ko active Active
- 2010-09-08 EP EP10815369.3A patent/EP2476429B1/en active Active
- 2010-09-08 CN CN201080034494.5A patent/CN102470164B/zh active Active
- 2010-09-08 IN IN857DEN2012 patent/IN2012DN00857A/en unknown
- 2010-09-08 NZ NZ598370A patent/NZ598370A/en unknown
- 2010-09-08 EP EP13181715.7A patent/EP2682125B1/en active Active
- 2010-09-08 ES ES13181713.2T patent/ES2662018T3/es active Active
- 2010-09-08 BR BR112012003511A patent/BR112012003511A2/pt not_active IP Right Cessation
- 2010-09-08 KR KR1020177019824A patent/KR20170089018A/ko not_active Ceased
- 2010-09-08 CA CA2772656A patent/CA2772656A1/en not_active Abandoned
- 2010-09-08 CN CN201410092512.5A patent/CN103893746A/zh active Pending
- 2010-09-08 EP EP13181713.2A patent/EP2682124B1/en active Active
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2012
- 2012-01-31 IL IL217854A patent/IL217854A/en active IP Right Grant
- 2012-03-08 ZA ZA2012/01720A patent/ZA201201720B/en unknown
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2014
- 2014-03-05 US US14/197,607 patent/US20140249084A1/en not_active Abandoned
- 2014-07-14 US US14/330,124 patent/US20140357560A1/en not_active Abandoned
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2015
- 2015-05-25 JP JP2015105265A patent/JP6150846B2/ja active Active
- 2015-05-25 JP JP2015105266A patent/JP6198346B2/ja active Active
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2016
- 2016-04-18 JP JP2016082589A patent/JP6043008B2/ja active Active
- 2016-11-10 JP JP2016219323A patent/JP2017061511A/ja active Pending
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2017
- 2017-03-27 JP JP2017061092A patent/JP6274634B2/ja active Active
- 2017-03-27 JP JP2017061095A patent/JP2017105862A/ja not_active Withdrawn
- 2017-03-27 JP JP2017061093A patent/JP6301524B2/ja active Active
- 2017-03-27 JP JP2017061091A patent/JP6275900B2/ja active Active
- 2017-03-27 JP JP2017061096A patent/JP2017105863A/ja active Pending
- 2017-03-27 JP JP2017061094A patent/JP2017105861A/ja not_active Withdrawn
- 2017-11-17 JP JP2017221570A patent/JP6522715B2/ja active Active
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2018
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