BR0112381A - Componente farmacêutico com base em hormÈnio da paratireóide humana e uma composição farmacêutica para administração intranasal compreendendo o componente - Google Patents
Componente farmacêutico com base em hormÈnio da paratireóide humana e uma composição farmacêutica para administração intranasal compreendendo o componenteInfo
- Publication number
- BR0112381A BR0112381A BR0112381-5A BR0112381A BR0112381A BR 0112381 A BR0112381 A BR 0112381A BR 0112381 A BR0112381 A BR 0112381A BR 0112381 A BR0112381 A BR 0112381A
- Authority
- BR
- Brazil
- Prior art keywords
- component
- human parathyroid
- parathyroid hormone
- pharmaceutical composition
- pharmaceutical
- Prior art date
Links
- 239000000306 component Substances 0.000 title abstract 5
- 101001135770 Homo sapiens Parathyroid hormone Proteins 0.000 title abstract 4
- 101001135995 Homo sapiens Probable peptidyl-tRNA hydrolase Proteins 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000005426 pharmaceutical component Substances 0.000 title abstract 2
- 102000058004 human PTH Human genes 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- 239000003688 hormone derivative Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 2
- 230000000849 parathyroid Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
"COMPONENTE FARMACêUTICO COM BASE EM HORMÈNIO DA PARATIREóIDE HUMANA E UMA COMPOSIçãO FARMACêUTICA PARA ADMINISTRAçãO INTRANASAL COMPREENDENDO O COMPONENTE". Um componente médico compreendendo um peptídeo de hormónio da paratireóide humana ou seu derivado, e ácido acético contido em uma concentração menor que seu equivalente químico com respeito ao peptídeo de hormónio da paratireóide humana ou ao seu derivado. Uma vez que o componente médico ácido acético, que está presente como um sal ou fixo ao peptídeo ou ao seu derivado, foi reduzido a uma quantidade menor que o equivalente químico com respeito ao peptídeo de hormónio da paratireóide humana ou seu derivado, um componente médico, que é altamente estável e assegurará uma excelente sensação de uso quando introduzido em uma composição farmacêutica, é obtido.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000237717 | 2000-06-30 | ||
| JP2000237718 | 2000-06-30 | ||
| PCT/JP2001/005674 WO2002002136A1 (fr) | 2000-06-30 | 2001-06-29 | Constituants medicinaux comportant de l'hormone parathyroidienne humaine et compositions medicinales pour l'administration nasale contenant lesdits constituants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0112381A true BR0112381A (pt) | 2003-05-06 |
Family
ID=26597441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0112381-5A BR0112381A (pt) | 2000-06-30 | 2001-06-29 | Componente farmacêutico com base em hormÈnio da paratireóide humana e uma composição farmacêutica para administração intranasal compreendendo o componente |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7087248B2 (pt) |
| EP (1) | EP1297842A4 (pt) |
| KR (1) | KR20030016315A (pt) |
| CN (1) | CN100518819C (pt) |
| AR (1) | AR032461A1 (pt) |
| AU (2) | AU6788701A (pt) |
| BR (1) | BR0112381A (pt) |
| CA (1) | CA2414966A1 (pt) |
| IL (1) | IL153678A0 (pt) |
| MX (1) | MXPA02012947A (pt) |
| MY (1) | MY136546A (pt) |
| NO (1) | NO325831B1 (pt) |
| NZ (1) | NZ523457A (pt) |
| RU (1) | RU2292219C2 (pt) |
| TW (1) | TWI293563B (pt) |
| WO (1) | WO2002002136A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8765124B2 (en) | 2003-02-28 | 2014-07-01 | Chugai Seiyaku Kabushiki Kaisha | Stabilized preparation containing protein |
| US20070213272A1 (en) * | 2004-07-14 | 2007-09-13 | Katsuhiko Sato | Transmucosal Administration Agent Containing Pth |
| AU2006315132A1 (en) * | 2005-11-10 | 2007-05-24 | Board Of Control Of Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
| EP1961765A1 (en) * | 2006-12-08 | 2008-08-27 | Zealand Pharma A/S | Truncated PTH peptides with a cyclic conformation |
| KR200449313Y1 (ko) * | 2008-02-18 | 2010-06-30 | 손복만 | 동파방지용 배수밸브를 구비한 가통 |
| JP2011001317A (ja) * | 2009-06-19 | 2011-01-06 | Fumakilla Ltd | 鼻用洗浄剤 |
| CN102470164B (zh) | 2009-09-09 | 2014-04-09 | 旭化成制药株式会社 | 以每周给药1次每次为100单位～200单位的pth为特征的、含有pth的骨质疏松症治疗/预防剂 |
| AU2010320272B2 (en) | 2009-11-18 | 2015-01-22 | Asahi Kasei Pharma Corporation | Preventive and/or therapeutic and/or aggravation suppressing agent for human arthritis deformans |
| EP2509996A1 (en) | 2009-12-07 | 2012-10-17 | Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
| EP2471554A1 (en) * | 2010-12-28 | 2012-07-04 | Hexal AG | Pharmaceutical formulation comprising a biopharmaceutical drug |
| CN108195965B (zh) * | 2011-06-07 | 2021-02-23 | 旭化成制药株式会社 | 含pth肽冷冻干燥制剂的检査方法及包含该含pth肽冷冻干燥制剂的医药品的制造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4086196A (en) * | 1975-03-28 | 1978-04-25 | Armour Pharmaceutical Company | Parathyroid hormone |
| JP2505812B2 (ja) | 1987-07-10 | 1996-06-12 | 旭化成工業株式会社 | ｈ―ＰＴＨ（１―３４）凍結乾燥組成物 |
| GB9020544D0 (en) | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5208041A (en) | 1991-05-23 | 1993-05-04 | Allelix Biopharmaceuticals Inc. | Essentially pure human parathyroid hormone |
| JPH05271279A (ja) * | 1991-08-07 | 1993-10-19 | Takeda Chem Ind Ltd | ヒト副甲状腺ホルモンムテインおよびその製造法 |
| US5977070A (en) * | 1992-07-14 | 1999-11-02 | Piazza; Christin Teresa | Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis |
| DE19538687A1 (de) | 1995-10-17 | 1997-04-24 | Boehringer Mannheim Gmbh | Stabile pharmazeutische Darreichungsformen enthaltend Parathormon |
-
2001
- 2001-06-29 MY MYPI20013133A patent/MY136546A/en unknown
- 2001-06-29 IL IL15367801A patent/IL153678A0/xx unknown
- 2001-06-29 KR KR1020027017881A patent/KR20030016315A/ko not_active Application Discontinuation
- 2001-06-29 TW TW090116031A patent/TWI293563B/zh not_active IP Right Cessation
- 2001-06-29 EP EP01945732A patent/EP1297842A4/en not_active Withdrawn
- 2001-06-29 RU RU2003102629/15A patent/RU2292219C2/ru not_active IP Right Cessation
- 2001-06-29 AR ARP010103122A patent/AR032461A1/es unknown
- 2001-06-29 WO PCT/JP2001/005674 patent/WO2002002136A1/ja active IP Right Grant
- 2001-06-29 AU AU6788701A patent/AU6788701A/xx active Pending
- 2001-06-29 NZ NZ523457A patent/NZ523457A/en not_active IP Right Cessation
- 2001-06-29 BR BR0112381-5A patent/BR0112381A/pt not_active Application Discontinuation
- 2001-06-29 AU AU2001267887A patent/AU2001267887B2/en not_active Ceased
- 2001-06-29 MX MXPA02012947A patent/MXPA02012947A/es active IP Right Grant
- 2001-06-29 US US10/312,726 patent/US7087248B2/en not_active Expired - Fee Related
- 2001-06-29 CN CNB018120636A patent/CN100518819C/zh not_active Expired - Fee Related
- 2001-06-29 CA CA002414966A patent/CA2414966A1/en not_active Abandoned
-
2002
- 2002-12-17 NO NO20026055A patent/NO325831B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6788701A (en) | 2002-01-14 |
| CN1440294A (zh) | 2003-09-03 |
| NO20026055L (no) | 2003-02-24 |
| CN100518819C (zh) | 2009-07-29 |
| NZ523457A (en) | 2004-11-26 |
| NO20026055D0 (no) | 2002-12-17 |
| TWI293563B (en) | 2008-02-21 |
| AU2001267887B2 (en) | 2007-02-15 |
| RU2292219C2 (ru) | 2007-01-27 |
| IL153678A0 (en) | 2003-07-06 |
| KR20030016315A (ko) | 2003-02-26 |
| WO2002002136A1 (fr) | 2002-01-10 |
| AR032461A1 (es) | 2003-11-12 |
| EP1297842A4 (en) | 2005-03-30 |
| US20050107292A1 (en) | 2005-05-19 |
| MY136546A (en) | 2008-10-31 |
| CA2414966A1 (en) | 2002-01-10 |
| EP1297842A1 (en) | 2003-04-02 |
| MXPA02012947A (es) | 2003-05-15 |
| US7087248B2 (en) | 2006-08-08 |
| NO325831B1 (no) | 2008-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Free format text: DAIICHI SUNTORY PHARMA CO. LTD. (JP) |
|
| B25D | Requested change of name of applicant approved |
Owner name: DAIICHI ASUBIO PHARMA CO., LTD. (JP) Free format text: ALTERADO DE: DAIICHI SUNTORY PHARMA CO., LTD. |
|
| B25D | Requested change of name of applicant approved |
Owner name: ASUBIO PHARMA CO., LTD. (JP) Free format text: ALTERADO DE: DAIICHI ASUBIO PHARMA CO., LTD. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |