BRPI0406499A - Insulina de longa atuação para redução da morbidez e mortalidade cardiovascular em pacientes pré-diabéticos e pacientes com diabetes tipo 2 - Google Patents
Insulina de longa atuação para redução da morbidez e mortalidade cardiovascular em pacientes pré-diabéticos e pacientes com diabetes tipo 2Info
- Publication number
- BRPI0406499A BRPI0406499A BR0406499-2A BRPI0406499A BRPI0406499A BR PI0406499 A BRPI0406499 A BR PI0406499A BR PI0406499 A BRPI0406499 A BR PI0406499A BR PI0406499 A BRPI0406499 A BR PI0406499A
- Authority
- BR
- Brazil
- Prior art keywords
- patients
- type
- mortality
- diabetes
- long
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
"INSULINA DE LONGA ATUAçãO PARA REDUçãO DA MORBIDEZ E MORTALIDADE CARDIOVASCULAR EM PACIENTES PRé-DIABéTICOS E PACIENTES COM DIABETES TIPO 2". A presente invenção refere-se a um método para redução da morbidez e mortalidade cardiovascular em uma população de paciente de Diabetes Tipo 2 ou pré-diabética. O método compreende administrar uma dosagem eficaz de uma insulina de longa atuação, preferivelmente, insulina glargina, a um paciente de Diabetes Tipo 2 ou pré-diabético.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43994103P | 2003-01-14 | 2003-01-14 | |
PCT/US2004/000879 WO2004064862A1 (en) | 2003-01-14 | 2004-01-14 | Long acting insulin for reducing cardiovascular morbidity and mortality in prediabetic patients and patients with type 2 diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0406499A true BRPI0406499A (pt) | 2005-12-06 |
Family
ID=23746761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0406499-2A BRPI0406499A (pt) | 2003-01-14 | 2004-01-14 | Insulina de longa atuação para redução da morbidez e mortalidade cardiovascular em pacientes pré-diabéticos e pacientes com diabetes tipo 2 |
Country Status (16)
Country | Link |
---|---|
US (4) | US7405196B2 (pt) |
EP (2) | EP2596800B1 (pt) |
JP (1) | JP5389325B2 (pt) |
AU (2) | AU2004206829B2 (pt) |
BR (1) | BRPI0406499A (pt) |
CA (1) | CA2512820C (pt) |
CY (1) | CY1118738T1 (pt) |
DK (1) | DK2596800T3 (pt) |
ES (1) | ES2604359T3 (pt) |
GB (1) | GB0309154D0 (pt) |
HU (1) | HUE031892T2 (pt) |
IL (3) | IL169697A (pt) |
MX (1) | MXPA05007470A (pt) |
PT (1) | PT2596800T (pt) |
SI (1) | SI2596800T1 (pt) |
WO (1) | WO2004064862A1 (pt) |
Families Citing this family (57)
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US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
WO2003080149A2 (en) | 2002-03-20 | 2003-10-02 | Mannkind Corporation | Inhalation apparatus |
WO2005012346A1 (en) * | 2003-07-25 | 2005-02-10 | Conjuchem, Inc. | Long lasting insulin derivatives and methods thereof |
JP5078014B2 (ja) | 2004-08-20 | 2012-11-21 | マンカインド コーポレイション | ジケトピペラジン合成の触媒反応 |
MX2007002189A (es) | 2004-08-23 | 2008-01-11 | Mannkind Corp | Sales de dicetopiperazina, sales de dicetomorfolina o sales de dicetodioxano para suministro de farmacos. |
US7803404B2 (en) | 2005-09-14 | 2010-09-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
IN2015DN00888A (pt) | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
KR101933816B1 (ko) | 2008-06-13 | 2019-03-29 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
WO2009155581A1 (en) | 2008-06-20 | 2009-12-23 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
PT3228320T (pt) | 2008-10-17 | 2020-03-26 | Sanofi Aventis Deutschland | Combinação de uma insulina e de um agonista do glp-1 |
KR101285520B1 (ko) | 2008-12-23 | 2013-07-17 | 에프. 호프만-라 로슈 아게 | 만성 질병을 가진 환자의 진단 또는 치료 지원을 위한 구조화된 테스팅 방법 및 그 디바이스 |
US10456036B2 (en) | 2008-12-23 | 2019-10-29 | Roche Diabetes Care, Inc. | Structured tailoring |
US9918635B2 (en) | 2008-12-23 | 2018-03-20 | Roche Diabetes Care, Inc. | Systems and methods for optimizing insulin dosage |
US10437962B2 (en) | 2008-12-23 | 2019-10-08 | Roche Diabetes Care Inc | Status reporting of a structured collection procedure |
US20120011125A1 (en) | 2008-12-23 | 2012-01-12 | Roche Diagnostics Operations, Inc. | Management method and system for implementation, execution, data collection, and data analysis of a structured collection procedure which runs on a collection device |
US8849458B2 (en) * | 2008-12-23 | 2014-09-30 | Roche Diagnostics Operations, Inc. | Collection device with selective display of test results, method and computer program product thereof |
US9117015B2 (en) | 2008-12-23 | 2015-08-25 | Roche Diagnostics Operations, Inc. | Management method and system for implementation, execution, data collection, and data analysis of a structured collection procedure which runs on a collection device |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PL2405963T3 (pl) | 2009-03-11 | 2014-04-30 | Mannkind Corp | Urządzenie, układ i sposób pomiaru oporu inhalatora |
BRPI1013154B1 (pt) | 2009-06-12 | 2020-04-07 | Mannkind Corp | Micropartículas de dicetopiperazina com áreas de superfície específicas definidas, pó seco compreendendo as referidas micropartículas, método para formação das referidasmicropartículas e formação de micropartículas de fumaril diacetopiperazina, uso das referidas micropartículas e sistema de inalação |
CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
JP5973918B2 (ja) | 2009-11-13 | 2016-08-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Glp−1アゴニスト及びメチオニンを含む薬学的組成物 |
TR201809460T4 (tr) | 2009-11-13 | 2018-07-23 | Sanofi Aventis Deutschland | Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim. |
AU2011202239C1 (en) * | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
US8532933B2 (en) | 2010-06-18 | 2013-09-10 | Roche Diagnostics Operations, Inc. | Insulin optimization systems and testing methods with adjusted exit criterion accounting for system noise associated with biomarkers |
MX359281B (es) | 2010-06-21 | 2018-09-21 | Mannkind Corp | Sistema y metodos para suministrar un farmaco en polvo seco. |
JP6199186B2 (ja) | 2010-08-30 | 2017-09-20 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 2型糖尿病の治療用の医薬の製造のためのave0010の使用 |
US20120173151A1 (en) | 2010-12-29 | 2012-07-05 | Roche Diagnostics Operations, Inc. | Methods of assessing diabetes treatment protocols based on protocol complexity levels and patient proficiency levels |
MX353285B (es) | 2011-04-01 | 2018-01-05 | Mannkind Corp | Paquete de blister para cartuchos farmaceuticos. |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
US8755938B2 (en) | 2011-05-13 | 2014-06-17 | Roche Diagnostics Operations, Inc. | Systems and methods for handling unacceptable values in structured collection protocols |
US8766803B2 (en) | 2011-05-13 | 2014-07-01 | Roche Diagnostics Operations, Inc. | Dynamic data collection |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
AR087693A1 (es) | 2011-08-29 | 2014-04-09 | Sanofi Aventis Deutschland | Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2 |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
IN2014DN03093A (pt) | 2011-10-24 | 2015-05-15 | Mannkind Corp | |
WO2013079691A1 (en) * | 2011-12-01 | 2013-06-06 | Sanofi | Insulin glargine versus metformin for the first-line treatment of early type 2 diabetes |
CA2865823A1 (en) * | 2012-03-28 | 2013-10-03 | Sanofi | Basal insulin therapy |
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WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
KR102499439B1 (ko) | 2013-03-15 | 2023-02-13 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
DK2983697T3 (en) | 2013-04-03 | 2019-02-25 | Sanofi Sa | TREATMENT OF DIABETES MELLITUS WITH LONG-EFFECTIVE FORMULATIONS OF INSULIN |
CA2918369C (en) | 2013-07-18 | 2021-06-29 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
WO2016001185A1 (en) * | 2014-07-02 | 2016-01-07 | Novo Nordisk A/S | Dosage regimen for the treatment of diabetes |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
CA2970200A1 (en) | 2014-12-12 | 2016-06-16 | Sanofi-Aventis Deutschland Gmbh | Insulin glargine/lixisenatide fixed ratio formulation |
TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
US20180369342A1 (en) * | 2015-12-23 | 2018-12-27 | Sanofi-Aventis Deutschland Gmbh | Cardiac metabolic effect of lantus |
CN110099719A (zh) * | 2016-11-28 | 2019-08-06 | 诺和诺德股份有限公司 | 用于改善血糖控制以及减少急性和长期糖尿病并发症的德谷胰岛素 |
WO2018096164A1 (en) * | 2016-11-28 | 2018-05-31 | Novo Nordisk A/S | Insulin degludec for treating diabetes |
CN110022935A (zh) | 2016-11-28 | 2019-07-16 | 诺和诺德股份有限公司 | 用于心血管病况的德谷胰岛素 |
US11366189B2 (en) * | 2020-09-25 | 2022-06-21 | Uih America, Inc. | Systems and methods for magnetic resonance imaging |
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US5354331A (en) | 1992-07-15 | 1994-10-11 | Schachar Ronald A | Treatment of presbyopia and other eye disorders |
DE69826286T2 (de) * | 1997-06-27 | 2005-11-24 | Fujisawa Pharmaceutical Co., Ltd. | Derivate mit einem aromatischen ring |
CO5271699A1 (es) | 2000-01-24 | 2003-04-30 | Pfizer Prod Inc | Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa |
EP1284723A4 (en) * | 2000-04-19 | 2004-06-30 | Borody Thomas J | COMPOSITIONS AND METHODS FOR TREATING DISORDERS ASSOCIATED WITH HYPERLIPIDEMIA |
JP4236464B2 (ja) * | 2000-10-26 | 2009-03-11 | フォーリナー ラボラトリーズ アイルランド リミテッド | 内皮機能不全治療用のフェノフィブラートと補酵素q10との組み合わせ |
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2003
- 2003-04-23 GB GBGB0309154.3A patent/GB0309154D0/en not_active Ceased
-
2004
- 2004-01-14 BR BR0406499-2A patent/BRPI0406499A/pt not_active Application Discontinuation
- 2004-01-14 PT PT131558017T patent/PT2596800T/pt unknown
- 2004-01-14 MX MXPA05007470A patent/MXPA05007470A/es active IP Right Grant
- 2004-01-14 DK DK13155801.7T patent/DK2596800T3/en active
- 2004-01-14 ES ES13155801.7T patent/ES2604359T3/es not_active Expired - Lifetime
- 2004-01-14 SI SI200432361A patent/SI2596800T1/sl unknown
- 2004-01-14 CA CA2512820A patent/CA2512820C/en not_active Expired - Lifetime
- 2004-01-14 HU HUE13155801A patent/HUE031892T2/en unknown
- 2004-01-14 JP JP2006500944A patent/JP5389325B2/ja not_active Expired - Lifetime
- 2004-01-14 EP EP13155801.7A patent/EP2596800B1/en not_active Expired - Lifetime
- 2004-01-14 EP EP04702167A patent/EP1589991A1/en not_active Withdrawn
- 2004-01-14 WO PCT/US2004/000879 patent/WO2004064862A1/en active Application Filing
- 2004-01-14 US US10/757,201 patent/US7405196B2/en active Active
- 2004-01-14 AU AU2004206829A patent/AU2004206829B2/en not_active Expired
-
2005
- 2005-07-14 IL IL169697A patent/IL169697A/en active IP Right Grant
-
2008
- 2008-06-17 US US12/140,598 patent/US7977310B2/en not_active Expired - Lifetime
-
2009
- 2009-03-22 IL IL197739A patent/IL197739A/en active IP Right Grant
-
2010
- 2010-06-30 AU AU2010202738A patent/AU2010202738B2/en not_active Expired
- 2010-10-06 IL IL208525A patent/IL208525A0/en unknown
-
2011
- 2011-06-03 US US13/152,932 patent/US20110281793A1/en not_active Abandoned
-
2012
- 2012-09-14 US US13/617,341 patent/US8809270B2/en not_active Expired - Lifetime
-
2016
- 2016-11-23 CY CY20161101212T patent/CY1118738T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU2010202738A1 (en) | 2010-07-22 |
CA2512820A1 (en) | 2004-08-05 |
JP2006515625A (ja) | 2006-06-01 |
AU2004206829A1 (en) | 2004-08-05 |
ES2604359T3 (es) | 2017-03-06 |
IL197739A0 (en) | 2011-08-01 |
HUE031892T2 (en) | 2017-08-28 |
WO2004064862A1 (en) | 2004-08-05 |
IL208525A0 (en) | 2010-12-30 |
EP1589991A1 (en) | 2005-11-02 |
DK2596800T3 (en) | 2016-12-12 |
IL169697A0 (en) | 2007-07-04 |
MXPA05007470A (es) | 2005-09-21 |
SI2596800T1 (sl) | 2017-04-26 |
IL169697A (en) | 2011-06-30 |
EP2596800B1 (en) | 2016-08-24 |
JP5389325B2 (ja) | 2014-01-15 |
PT2596800T (pt) | 2016-12-02 |
US20080287343A1 (en) | 2008-11-20 |
GB0309154D0 (en) | 2003-05-28 |
US20130012433A1 (en) | 2013-01-10 |
AU2004206829B2 (en) | 2010-04-08 |
US20110281793A1 (en) | 2011-11-17 |
EP2596800A1 (en) | 2013-05-29 |
US8809270B2 (en) | 2014-08-19 |
AU2010202738B2 (en) | 2013-12-05 |
CY1118738T1 (el) | 2017-07-12 |
CA2512820C (en) | 2013-06-04 |
IL197739A (en) | 2017-02-28 |
US20040229774A1 (en) | 2004-11-18 |
US7405196B2 (en) | 2008-07-29 |
US7977310B2 (en) | 2011-07-12 |
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Legal Events
Date | Code | Title | Description |
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B25G | Requested change of headquarter approved |
Owner name: AVENTIS PHARMACEUTICALS, INC. (US) Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070165509/RJ DE 23/11/2007. |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |