PT2596800T - Utilização de insulina glargina para reduzir ou prevenir a morbidade e mortalidade cardiovasculares em doentes pré- diabéticos - Google Patents
Utilização de insulina glargina para reduzir ou prevenir a morbidade e mortalidade cardiovasculares em doentes pré- diabéticosInfo
- Publication number
- PT2596800T PT2596800T PT131558017T PT13155801T PT2596800T PT 2596800 T PT2596800 T PT 2596800T PT 131558017 T PT131558017 T PT 131558017T PT 13155801 T PT13155801 T PT 13155801T PT 2596800 T PT2596800 T PT 2596800T
- Authority
- PT
- Portugal
- Prior art keywords
- mortality
- reduce
- insulin glargine
- diabetes patients
- prevent cardiovascular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43994103P | 2003-01-14 | 2003-01-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2596800T true PT2596800T (pt) | 2016-12-02 |
Family
ID=23746761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT131558017T PT2596800T (pt) | 2003-01-14 | 2004-01-14 | Utilização de insulina glargina para reduzir ou prevenir a morbidade e mortalidade cardiovasculares em doentes pré- diabéticos |
Country Status (16)
Country | Link |
---|---|
US (4) | US7405196B2 (pt) |
EP (2) | EP1589991A1 (pt) |
JP (1) | JP5389325B2 (pt) |
AU (2) | AU2004206829B2 (pt) |
BR (1) | BRPI0406499A (pt) |
CA (1) | CA2512820C (pt) |
CY (1) | CY1118738T1 (pt) |
DK (1) | DK2596800T3 (pt) |
ES (1) | ES2604359T3 (pt) |
GB (1) | GB0309154D0 (pt) |
HU (1) | HUE031892T2 (pt) |
IL (3) | IL169697A (pt) |
MX (1) | MXPA05007470A (pt) |
PT (1) | PT2596800T (pt) |
SI (1) | SI2596800T1 (pt) |
WO (1) | WO2004064862A1 (pt) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
ES2300568T3 (es) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | Aparato de inhalacion. |
CA2526957C (en) * | 2003-07-25 | 2011-07-12 | Conjuchem Inc. | Long lasting insulin derivatives and methods thereof |
JP5078014B2 (ja) | 2004-08-20 | 2012-11-21 | マンカインド コーポレイション | ジケトピペラジン合成の触媒反応 |
ES2543007T3 (es) | 2004-08-23 | 2015-08-13 | Mannkind Corporation | Micropartículas que comprenden sales de dicetopiperazina para la administración de fármacos |
JP5465878B2 (ja) | 2005-09-14 | 2014-04-09 | マンカインド コーポレイション | 活性薬剤に対する結晶性微粒子表面の親和性を増大させることに基づく薬物処方の方法 |
MX360812B (es) | 2006-02-22 | 2018-11-16 | Mannkind Corp | Un método para mejorar las propiedades farmacéuticas de micropartículas que contienen dicetopiperazina y un agente activo. |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
KR101629154B1 (ko) | 2008-06-13 | 2016-06-21 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
AU2009259883B2 (en) | 2008-06-20 | 2015-02-05 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
DK3228320T3 (da) | 2008-10-17 | 2020-03-09 | Sanofi Aventis Deutschland | Kombination af et insulin og en glp-1-agonist |
US8849458B2 (en) * | 2008-12-23 | 2014-09-30 | Roche Diagnostics Operations, Inc. | Collection device with selective display of test results, method and computer program product thereof |
US10456036B2 (en) * | 2008-12-23 | 2019-10-29 | Roche Diabetes Care, Inc. | Structured tailoring |
US9117015B2 (en) | 2008-12-23 | 2015-08-25 | Roche Diagnostics Operations, Inc. | Management method and system for implementation, execution, data collection, and data analysis of a structured collection procedure which runs on a collection device |
US20120011125A1 (en) | 2008-12-23 | 2012-01-12 | Roche Diagnostics Operations, Inc. | Management method and system for implementation, execution, data collection, and data analysis of a structured collection procedure which runs on a collection device |
US10437962B2 (en) | 2008-12-23 | 2019-10-08 | Roche Diabetes Care Inc | Status reporting of a structured collection procedure |
US9918635B2 (en) | 2008-12-23 | 2018-03-20 | Roche Diabetes Care, Inc. | Systems and methods for optimizing insulin dosage |
EP4246522A3 (en) | 2008-12-23 | 2023-11-08 | Roche Diabetes Care GmbH | Structured testing method for diagnostic or therapy support of a patient with a chronic disease and devices thereof |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
KR20210027546A (ko) | 2009-06-12 | 2021-03-10 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
KR101337322B1 (ko) | 2009-11-13 | 2013-12-06 | 사노피-아벤티스 도이칠란트 게엠베하 | Glp-1 효능제 및 메티오닌을 포함하는 약제학적 조성물 |
ES2676373T3 (es) | 2009-11-13 | 2018-07-19 | Sanofi-Aventis Deutschland Gmbh | Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina |
AU2011202239C1 (en) | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
US8532933B2 (en) | 2010-06-18 | 2013-09-10 | Roche Diagnostics Operations, Inc. | Insulin optimization systems and testing methods with adjusted exit criterion accounting for system noise associated with biomarkers |
CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
HUE031181T2 (en) | 2010-08-30 | 2017-06-28 | Sanofi Aventis Deutschland | Use of AVE0010 for the manufacture of a medicament for the treatment of type 2 diabetes |
US20120173151A1 (en) | 2010-12-29 | 2012-07-05 | Roche Diagnostics Operations, Inc. | Methods of assessing diabetes treatment protocols based on protocol complexity levels and patient proficiency levels |
BR112013025395B1 (pt) | 2011-04-01 | 2022-02-01 | Mannkind Corporation | Embalagem de bolha e método de fabricação de uma embalagem de bolhas |
US8755938B2 (en) | 2011-05-13 | 2014-06-17 | Roche Diagnostics Operations, Inc. | Systems and methods for handling unacceptable values in structured collection protocols |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
US8766803B2 (en) | 2011-05-13 | 2014-07-01 | Roche Diagnostics Operations, Inc. | Dynamic data collection |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
ES2550357T3 (es) | 2011-08-29 | 2015-11-06 | Sanofi-Aventis Deutschland Gmbh | Combinación farmacéutica para su uso en el control glucémico en pacientes de diabetes de tipo 2 |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
US9233159B2 (en) | 2011-10-24 | 2016-01-12 | Mannkind Corporation | Methods and compositions for treating pain |
WO2013079691A1 (en) * | 2011-12-01 | 2013-06-06 | Sanofi | Insulin glargine versus metformin for the first-line treatment of early type 2 diabetes |
CN104334183A (zh) * | 2012-03-28 | 2015-02-04 | 赛诺菲 | 基底胰岛素治疗 |
EP2872205B1 (en) | 2012-07-12 | 2017-02-08 | MannKind Corporation | Dry powder drug delivery systems |
US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
ES2928365T3 (es) | 2013-03-15 | 2022-11-17 | Mannkind Corp | Composiciones de dicetopiperazina microcristalina, métodos de preparación y uso del mismo |
MY181626A (en) | 2013-04-03 | 2020-12-29 | Sanofi Sa | Treatment of diabetes mellitus by long-acting formulations of insulins |
US9925144B2 (en) | 2013-07-18 | 2018-03-27 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
CN105517607A (zh) | 2013-08-05 | 2016-04-20 | 曼金德公司 | 吹入设备和方法 |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
WO2016001185A1 (en) * | 2014-07-02 | 2016-01-07 | Novo Nordisk A/S | Dosage regimen for the treatment of diabetes |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
MX2017007699A (es) | 2014-12-12 | 2017-09-18 | Sanofi Aventis Deutschland | Formulacion de proporcion fija de insulina glargina/lixisenatida. |
TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
WO2017108943A1 (en) * | 2015-12-23 | 2017-06-29 | Sanofi-Aventis Deutschland Gmbh | Cardiac metabolic effect of lantus |
WO2018096164A1 (en) * | 2016-11-28 | 2018-05-31 | Novo Nordisk A/S | Insulin degludec for treating diabetes |
CN110099719A (zh) * | 2016-11-28 | 2019-08-06 | 诺和诺德股份有限公司 | 用于改善血糖控制以及减少急性和长期糖尿病并发症的德谷胰岛素 |
JP7193455B2 (ja) * | 2016-11-28 | 2022-12-20 | ノヴォ ノルディスク アー/エス | 心血管状態におけるインスリンデグルデク |
US11366189B2 (en) | 2020-09-25 | 2022-06-21 | Uih America, Inc. | Systems and methods for magnetic resonance imaging |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5354331A (en) | 1992-07-15 | 1994-10-11 | Schachar Ronald A | Treatment of presbyopia and other eye disorders |
DE69826286T2 (de) * | 1997-06-27 | 2005-11-24 | Fujisawa Pharmaceutical Co., Ltd. | Derivate mit einem aromatischen ring |
CO5271699A1 (es) | 2000-01-24 | 2003-04-30 | Pfizer Prod Inc | Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa |
BR0110208A (pt) * | 2000-04-19 | 2003-01-28 | Borody Thomas J | Composições e terapias para distúrbios associados com hiperlipidemia |
JP4236464B2 (ja) * | 2000-10-26 | 2009-03-11 | フォーリナー ラボラトリーズ アイルランド リミテッド | 内皮機能不全治療用のフェノフィブラートと補酵素q10との組み合わせ |
-
2003
- 2003-04-23 GB GBGB0309154.3A patent/GB0309154D0/en not_active Ceased
-
2004
- 2004-01-14 CA CA2512820A patent/CA2512820C/en not_active Expired - Lifetime
- 2004-01-14 WO PCT/US2004/000879 patent/WO2004064862A1/en active Application Filing
- 2004-01-14 AU AU2004206829A patent/AU2004206829B2/en not_active Expired
- 2004-01-14 EP EP04702167A patent/EP1589991A1/en not_active Withdrawn
- 2004-01-14 DK DK13155801.7T patent/DK2596800T3/en active
- 2004-01-14 ES ES13155801.7T patent/ES2604359T3/es not_active Expired - Lifetime
- 2004-01-14 BR BR0406499-2A patent/BRPI0406499A/pt not_active Application Discontinuation
- 2004-01-14 MX MXPA05007470A patent/MXPA05007470A/es active IP Right Grant
- 2004-01-14 PT PT131558017T patent/PT2596800T/pt unknown
- 2004-01-14 JP JP2006500944A patent/JP5389325B2/ja not_active Expired - Lifetime
- 2004-01-14 US US10/757,201 patent/US7405196B2/en active Active
- 2004-01-14 EP EP13155801.7A patent/EP2596800B1/en not_active Expired - Lifetime
- 2004-01-14 SI SI200432361A patent/SI2596800T1/sl unknown
- 2004-01-14 HU HUE13155801A patent/HUE031892T2/en unknown
-
2005
- 2005-07-14 IL IL169697A patent/IL169697A/en active IP Right Grant
-
2008
- 2008-06-17 US US12/140,598 patent/US7977310B2/en not_active Expired - Lifetime
-
2009
- 2009-03-22 IL IL197739A patent/IL197739A/en active IP Right Grant
-
2010
- 2010-06-30 AU AU2010202738A patent/AU2010202738B2/en not_active Expired
- 2010-10-06 IL IL208525A patent/IL208525A0/en unknown
-
2011
- 2011-06-03 US US13/152,932 patent/US20110281793A1/en not_active Abandoned
-
2012
- 2012-09-14 US US13/617,341 patent/US8809270B2/en not_active Expired - Lifetime
-
2016
- 2016-11-23 CY CY20161101212T patent/CY1118738T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2512820A1 (en) | 2004-08-05 |
WO2004064862A1 (en) | 2004-08-05 |
IL169697A0 (en) | 2007-07-04 |
IL197739A (en) | 2017-02-28 |
US20110281793A1 (en) | 2011-11-17 |
US20080287343A1 (en) | 2008-11-20 |
GB0309154D0 (en) | 2003-05-28 |
JP2006515625A (ja) | 2006-06-01 |
BRPI0406499A (pt) | 2005-12-06 |
AU2004206829B2 (en) | 2010-04-08 |
AU2004206829A1 (en) | 2004-08-05 |
EP1589991A1 (en) | 2005-11-02 |
US20130012433A1 (en) | 2013-01-10 |
IL208525A0 (en) | 2010-12-30 |
AU2010202738B2 (en) | 2013-12-05 |
JP5389325B2 (ja) | 2014-01-15 |
DK2596800T3 (en) | 2016-12-12 |
US20040229774A1 (en) | 2004-11-18 |
SI2596800T1 (sl) | 2017-04-26 |
IL169697A (en) | 2011-06-30 |
ES2604359T3 (es) | 2017-03-06 |
IL197739A0 (en) | 2011-08-01 |
EP2596800B1 (en) | 2016-08-24 |
US7405196B2 (en) | 2008-07-29 |
HUE031892T2 (en) | 2017-08-28 |
CY1118738T1 (el) | 2017-07-12 |
EP2596800A1 (en) | 2013-05-29 |
MXPA05007470A (es) | 2005-09-21 |
US7977310B2 (en) | 2011-07-12 |
CA2512820C (en) | 2013-06-04 |
AU2010202738A1 (en) | 2010-07-22 |
US8809270B2 (en) | 2014-08-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SI2596800T1 (sl) | Uporaba inzulina glargina za zniževanje ali preprečevanje kardiovaskularne obolevnosti in umrljivosti pri prediabetičnih pacientih | |
NO2024003I1 (no) | combination of insulin degludec and insulin aspart | |
HUP0203367A3 (en) | Benzylidine-thiazolidinediones and analogues and their use in the treatment of diabetes | |
IL163278A (en) | Formulations including glp-1 compounds and their use in drug preparation | |
GB0212551D0 (en) | Improvements in and relating to optical devices | |
IL188732A (en) | Use of ibuprofen and pamotidine for drug preparation | |
IL180650A0 (en) | Infusion and injection solution of levodopa | |
EP1586332A4 (en) | COMBINED USE OF CARNOSINAS INHIBITOR WITH L-CARNOSINES AND COMPOSITION | |
ZA200610786B (en) | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | |
GB0205559D0 (en) | Improvements in and relating to the filling of explosive ordnance | |
AU2003207824A8 (en) | K-type polarizer and preparation thereof | |
EP1691779A4 (en) | TREATMENT OF A STATE IN A MAMMALIAN WITH THE ADMINISTRATION OF COMPOUNDS AND APPLICATION METHOD THEREFOR | |
IL169369A0 (en) | Thienopyridazinones and their use in modulation of autoimmune disease | |
GB0324965D0 (en) | Improvements in and relating to pumps | |
GB0207596D0 (en) | Improvements in or relating to patient support structures and their use | |
GB0304875D0 (en) | Improvements in and relating to display devices | |
GB2408468B (en) | Improvements in and relating to pumps | |
GB0217559D0 (en) | Improvements in and relating to kettles | |
GB2395832B (en) | Improvements in and relating to display devices | |
TW551100U (en) | Structure of display body easy in storing article | |
TW583934U (en) | Improved structure of leg easy in positioning and assembly | |
GB0311282D0 (en) | Improvements in and relating to pumping | |
GB0228951D0 (en) | Improvements in and relating to medicine packs | |
GB0201154D0 (en) | Improvements in and relating to imaging | |
GB0227123D0 (en) | Improvements in and relating to ladders |