KR102409246B1 - 면역조정제 - Google Patents

면역조정제 Download PDF

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Publication number
KR102409246B1
KR102409246B1 KR1020187028087A KR20187028087A KR102409246B1 KR 102409246 B1 KR102409246 B1 KR 102409246B1 KR 1020187028087 A KR1020187028087 A KR 1020187028087A KR 20187028087 A KR20187028087 A KR 20187028087A KR 102409246 B1 KR102409246 B1 KR 102409246B1
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dmf
resin
fmoc
frit
solution
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KR20180118724A (ko
Inventor
마틴 패트릭 알렌
에릭 피. 길리스
데이비드 알. 랭글리
마이클 매튜 밀러
에릭 멀
리-치앙 순
캅-선 융
캐서린 에이. 그랜트-영
니콜라스 에이. 민웰
폴 마이클 스콜라
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브리스톨-마이어스 스큅 컴퍼니
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/575—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020187028087A 2016-03-04 2017-03-02 면역조정제 Active KR102409246B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662303673P 2016-03-04 2016-03-04
US62/303,673 2016-03-04
PCT/US2017/020304 WO2017151830A1 (en) 2016-03-04 2017-03-02 Immunomodulators

Publications (2)

Publication Number Publication Date
KR20180118724A KR20180118724A (ko) 2018-10-31
KR102409246B1 true KR102409246B1 (ko) 2022-06-14

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Country Status (19)

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US (1) US10143746B2 (enExample)
EP (1) EP3423470B1 (enExample)
JP (1) JP6976263B2 (enExample)
KR (1) KR102409246B1 (enExample)
CN (1) CN109153703B (enExample)
AR (1) AR107802A1 (enExample)
AU (1) AU2017227777B2 (enExample)
BR (1) BR112018017114A2 (enExample)
CA (1) CA3016024A1 (enExample)
CL (1) CL2018002506A1 (enExample)
CO (1) CO2018010316A2 (enExample)
EA (1) EA035134B1 (enExample)
ES (1) ES2886635T3 (enExample)
IL (1) IL261408B (enExample)
MX (1) MX379487B (enExample)
SG (1) SG11201807426WA (enExample)
TW (1) TW201734022A (enExample)
UY (1) UY37143A (enExample)
WO (1) WO2017151830A1 (enExample)

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MX2018010414A (es) 2018-11-09
WO2017151830A1 (en) 2017-09-08
CA3016024A1 (en) 2017-09-08
SG11201807426WA (en) 2018-09-27
MX379487B (es) 2025-03-11
AR107802A1 (es) 2018-06-06
AU2017227777B2 (en) 2021-07-01
CN109153703A (zh) 2019-01-04
JP2019512478A (ja) 2019-05-16
JP6976263B2 (ja) 2021-12-08
AU2017227777A1 (en) 2018-10-25
KR20180118724A (ko) 2018-10-31
EP3423470A1 (en) 2019-01-09
IL261408B (en) 2022-01-01
EA201891879A1 (ru) 2019-02-28
BR112018017114A2 (en) 2018-12-26
US10143746B2 (en) 2018-12-04
EA035134B1 (ru) 2020-04-30
CN109153703B (zh) 2022-09-23
ES2886635T3 (es) 2021-12-20
US20170252432A1 (en) 2017-09-07
EP3423470B1 (en) 2021-08-18
UY37143A (es) 2017-08-31
CL2018002506A1 (es) 2018-11-09
CO2018010316A2 (es) 2018-10-22
IL261408A (en) 2018-10-31
TW201734022A (zh) 2017-10-01

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