EA035134B1 - Иммуномодуляторы - Google Patents

Иммуномодуляторы Download PDF

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Publication number
EA035134B1
EA035134B1 EA201891879A EA201891879A EA035134B1 EA 035134 B1 EA035134 B1 EA 035134B1 EA 201891879 A EA201891879 A EA 201891879A EA 201891879 A EA201891879 A EA 201891879A EA 035134 B1 EA035134 B1 EA 035134B1
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EA
Eurasian Patent Office
Prior art keywords
dmf
resin
frit
solution
fmoc
Prior art date
Application number
EA201891879A
Other languages
English (en)
Russian (ru)
Other versions
EA201891879A1 (ru
Inventor
Мартин Патрик Аллен
Эрик П. Гиллис
Дэвид Р. Лэнгли
Майкл Мэттью Миллер
Эрик Мулл
Ли-Цян Сунь
Кап-Сунь Йеун
Кэтерин А. Грант-Янг
Николас А. Минвелл
Пол Майкл Скола
Original Assignee
Бристол-Майерс Сквибб Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Бристол-Майерс Сквибб Компани filed Critical Бристол-Майерс Сквибб Компани
Publication of EA201891879A1 publication Critical patent/EA201891879A1/ru
Publication of EA035134B1 publication Critical patent/EA035134B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
EA201891879A 2016-03-04 2017-03-02 Иммуномодуляторы EA035134B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662303673P 2016-03-04 2016-03-04
PCT/US2017/020304 WO2017151830A1 (en) 2016-03-04 2017-03-02 Immunomodulators

Publications (2)

Publication Number Publication Date
EA201891879A1 EA201891879A1 (ru) 2019-02-28
EA035134B1 true EA035134B1 (ru) 2020-04-30

Family

ID=58347940

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201891879A EA035134B1 (ru) 2016-03-04 2017-03-02 Иммуномодуляторы

Country Status (19)

Country Link
US (1) US10143746B2 (enExample)
EP (1) EP3423470B1 (enExample)
JP (1) JP6976263B2 (enExample)
KR (1) KR102409246B1 (enExample)
CN (1) CN109153703B (enExample)
AR (1) AR107802A1 (enExample)
AU (1) AU2017227777B2 (enExample)
BR (1) BR112018017114A2 (enExample)
CA (1) CA3016024A1 (enExample)
CL (1) CL2018002506A1 (enExample)
CO (1) CO2018010316A2 (enExample)
EA (1) EA035134B1 (enExample)
ES (1) ES2886635T3 (enExample)
IL (1) IL261408B (enExample)
MX (1) MX379487B (enExample)
SG (1) SG11201807426WA (enExample)
TW (1) TW201734022A (enExample)
UY (1) UY37143A (enExample)
WO (1) WO2017151830A1 (enExample)

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BR112018073642A2 (pt) 2016-05-19 2019-02-26 Bristol-Myers Squibb Company imunomoduladores para imagiologia tep
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WO2021205631A1 (ja) 2020-04-10 2021-10-14 小野薬品工業株式会社 Ｓｔｉｎｇ作動化合物
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Also Published As

Publication number Publication date
CA3016024A1 (en) 2017-09-08
WO2017151830A1 (en) 2017-09-08
JP2019512478A (ja) 2019-05-16
TW201734022A (zh) 2017-10-01
EA201891879A1 (ru) 2019-02-28
EP3423470B1 (en) 2021-08-18
JP6976263B2 (ja) 2021-12-08
CO2018010316A2 (es) 2018-10-22
AU2017227777B2 (en) 2021-07-01
UY37143A (es) 2017-08-31
KR102409246B1 (ko) 2022-06-14
US10143746B2 (en) 2018-12-04
MX379487B (es) 2025-03-11
AU2017227777A1 (en) 2018-10-25
US20170252432A1 (en) 2017-09-07
IL261408A (en) 2018-10-31
ES2886635T3 (es) 2021-12-20
EP3423470A1 (en) 2019-01-09
CL2018002506A1 (es) 2018-11-09
IL261408B (en) 2022-01-01
BR112018017114A2 (en) 2018-12-26
KR20180118724A (ko) 2018-10-31
CN109153703B (zh) 2022-09-23
SG11201807426WA (en) 2018-09-27
CN109153703A (zh) 2019-01-04
AR107802A1 (es) 2018-06-06
MX2018010414A (es) 2018-11-09

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