KR102368450B1 - Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법 - Google Patents

Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법 Download PDF

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KR102368450B1
KR102368450B1 KR1020167025669A KR20167025669A KR102368450B1 KR 102368450 B1 KR102368450 B1 KR 102368450B1 KR 1020167025669 A KR1020167025669 A KR 1020167025669A KR 20167025669 A KR20167025669 A KR 20167025669A KR 102368450 B1 KR102368450 B1 KR 102368450B1
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antibody
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KR20160113733A (ko
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지안루카 피로치
프랭크 스코비에란다
용타오 리
네일 그라함
스티븐 피. 웨인스타인
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사노피 바이오테크놀로지
리제너론 파아마슈티컬스, 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020167025669A 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법 Active KR102368450B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227006120A KR20220029765A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461943019P 2014-02-21 2014-02-21
US61/943,019 2014-02-21
EP14306413 2014-09-15
EP14306413.7 2014-09-15
US201462077669P 2014-11-10 2014-11-10
US62/077,669 2014-11-10
PCT/US2015/016852 WO2015127229A1 (en) 2014-02-21 2015-02-20 Methods for treating or preventing asthma by administering an il-4r antagonist

Related Child Applications (1)

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KR1020227006120A Division KR20220029765A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법

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KR20160113733A KR20160113733A (ko) 2016-09-30
KR102368450B1 true KR102368450B1 (ko) 2022-02-28

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KR1020167025669A Active KR102368450B1 (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법
KR1020227006120A Ceased KR20220029765A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법
KR1020237041236A Ceased KR20230167770A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법
KR1020257035292A Pending KR20250154567A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법

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KR1020227006120A Ceased KR20220029765A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법
KR1020237041236A Ceased KR20230167770A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법
KR1020257035292A Pending KR20250154567A (ko) 2014-02-21 2015-02-20 Ｉｌ-4ｒ 길항제의 투여에 의한 천식의 치료 또는 예방 방법

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US (3) US10137193B2 (https=)
EP (3) EP3107575B1 (https=)
JP (3) JP6673840B2 (https=)
KR (4) KR102368450B1 (https=)
CN (1) CN106232140A (https=)
AU (3) AU2015218808B2 (https=)
CA (2) CA3249780A1 (https=)
ES (2) ES2897631T3 (https=)
HU (1) HUE065844T2 (https=)
IL (1) IL315136A (https=)
MX (2) MX384192B (https=)
PL (2) PL3973987T3 (https=)
PT (2) PT3973987T (https=)
RU (1) RU2713406C2 (https=)
WO (1) WO2015127229A1 (https=)

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KR20240053586A (ko) * 2021-08-26 2024-04-24 치아타이 티안큉 파마수티컬 그룹 주식회사 항il4r 항체의 의약 조성물 및 그의 사용
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