KR102321320B1 - 항-보체 인자 ｃ１ｑ 항체 및 이의 용도 - Google Patents

항-보체 인자 ｃ１ｑ 항체 및 이의 용도 Download PDF

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KR102321320B1
KR102321320B1 KR1020167002968A KR20167002968A KR102321320B1 KR 102321320 B1 KR102321320 B1 KR 102321320B1 KR 1020167002968 A KR1020167002968 A KR 1020167002968A KR 20167002968 A KR20167002968 A KR 20167002968A KR 102321320 B1 KR102321320 B1 KR 102321320B1
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antibodies
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KR20160058752A (ko
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아르논 로젠탈
마이클 레비텐
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애넥슨, 인코포레이티드
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    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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KR1020167002968A 2013-07-09 2014-07-09 항-보체 인자 ｃ１ｑ 항체 및 이의 용도 Active KR102321320B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361844369P 2013-07-09 2013-07-09
US61/844,369 2013-07-09
US201361871813P 2013-08-29 2013-08-29
US61/871,813 2013-08-29
PCT/US2014/046042 WO2015006504A1 (en) 2013-07-09 2014-07-09 Anti-complement factor c1q antibodies and uses thereof

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KR20160058752A KR20160058752A (ko) 2016-05-25
KR102321320B1 true KR102321320B1 (ko) 2021-11-03

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US (7) US20160159890A1 (https=)
EP (3) EP3019523A4 (https=)
JP (2) JP6462680B2 (https=)
KR (1) KR102321320B1 (https=)
CN (1) CN105682740B (https=)
AU (1) AU2014287221C1 (https=)
BR (1) BR112016000106B1 (https=)
CA (1) CA2916521C (https=)
DK (1) DK3019240T3 (https=)
EA (1) EA037325B1 (https=)
ES (1) ES2978917T3 (https=)
FI (1) FI3019240T3 (https=)
HU (1) HUE066722T2 (https=)
IL (1) IL243506B (https=)
MX (2) MX375500B (https=)
MY (1) MY175896A (https=)
NZ (1) NZ715455A (https=)
PL (1) PL3019240T3 (https=)
PT (1) PT3019240T (https=)
SG (3) SG10201710758PA (https=)
SI (1) SI3019240T1 (https=)
WO (2) WO2015006507A1 (https=)
ZA (1) ZA201600157B (https=)

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US9480658B2 (en) 2005-12-09 2016-11-01 The Board Of Trustees Of The Leland Stanford Junior University Modulation of synaptic maintenance
US8148330B2 (en) 2005-12-09 2012-04-03 The Board Of Trustees Of The Leland Stanford Junior University Modulation of synaptic maintenance
CN104870475B (zh) 2012-10-25 2019-11-08 美国比奥维拉迪维股份有限公司 抗补体C1s抗体和其用途
DK2914291T3 (da) 2012-11-02 2022-05-16 Bioverativ Usa Inc Anti-komplement-c1s-antistoffer og anvendelser deraf
EP2996722A4 (en) * 2013-05-15 2017-01-11 Annexon, Inc. Methods of treatment for guillain-barre syndrome
WO2015006507A1 (en) 2013-07-09 2015-01-15 Annexon, Inc. Methods of treatment for alzheimer's disease and huntington's disease
HUE070383T2 (hu) * 2014-11-05 2025-06-28 Annexon Inc Humanizált C1Q anti-komplement faktor antitestek és alkalmazásaik
WO2016164358A1 (en) 2015-04-06 2016-10-13 True North Therapeutics, Inc. Humanized anti-c1s antibodies and methods of use thereof
CN107708733B (zh) 2015-04-07 2022-11-15 艾利妥 抗分拣蛋白抗体和其使用方法
WO2017091719A1 (en) * 2015-11-24 2017-06-01 Annexon, Inc. Anti-complement factor c1q fab fragments and uses thereof
KR20190005944A (ko) * 2016-05-09 2019-01-16 애넥슨, 인코포레이티드 척수성 근위축 치료용 조성물 및 방법
CA3030872A1 (en) * 2016-07-19 2018-01-25 Annexon, Inc. Compositions and methods for treating frontotemporal dementia
CN116731197A (zh) * 2016-09-19 2023-09-12 豪夫迈·罗氏有限公司 基于补体因子的亲和层析
HUE073475T2 (hu) * 2016-10-12 2026-01-28 Bioverativ Usa Inc C1s elleni antitestek és alkalmazási eljárásaik
CN106699883B (zh) * 2016-12-19 2020-08-07 中国兽医药品监察所 豚鼠补体C1q-B单克隆抗体60G4的制备与应用
CN106822863A (zh) * 2017-01-04 2017-06-13 国家纳米科学中心 多肽‑抗体免疫偶联物及其制备方法
CN109843927B (zh) * 2017-03-06 2022-06-21 江苏恒瑞医药股份有限公司 抗b7-h3抗体、其抗原结合片段及其医药用途
PT3687287T (pt) * 2017-09-29 2023-11-03 Regeneron Pharma Roedores que expressam complexo c1q humanizado
EP3710589A4 (en) 2017-11-14 2021-11-10 Chugai Seiyaku Kabushiki Kaisha ANTI-C1S ANTIBODIES AND METHOD OF USING
EP3737472A1 (en) * 2018-01-09 2020-11-18 Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie Modulators of c1q, in particular of the interaction of apoe with c1q, and uses of the modulators in the therapy of neuronal diseases and inflammation
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