KR102271245B1 - Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법 - Google Patents

Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법 Download PDF

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KR102271245B1
KR102271245B1 KR1020207011312A KR20207011312A KR102271245B1 KR 102271245 B1 KR102271245 B1 KR 102271245B1 KR 1020207011312 A KR1020207011312 A KR 1020207011312A KR 20207011312 A KR20207011312 A KR 20207011312A KR 102271245 B1 KR102271245 B1 KR 102271245B1
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dsrna
tmprss6
irna
nucleotides
expression
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KR20200046114A (ko
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데이비드 범크로트
브라이언 베텐코트
이반카 토드자스카
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알닐람 파마슈티칼스 인코포레이티드
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KR1020207011312A 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법 Active KR102271245B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217019436A KR102365961B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161468830P 2011-03-29 2011-03-29
US61/468,830 2011-03-29
US201161568942P 2011-12-09 2011-12-09
US61/568,942 2011-12-09
KR1020137028251A KR102104401B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
PCT/US2012/030786 WO2012135246A2 (en) 2011-03-29 2012-03-28 Compositions and methods for inhibiting expression of tmprss6 gene

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KR1020137028251A Division KR102104401B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법

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KR1020217019436A Division KR102365961B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법

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KR20200046114A KR20200046114A (ko) 2020-05-06
KR102271245B1 true KR102271245B1 (ko) 2021-07-02

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KR1020227005359A Active KR102481317B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
KR1020217019436A Active KR102365961B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
KR1020207011312A Active KR102271245B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
KR1020137028251A Active KR102104401B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법

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KR1020227005359A Active KR102481317B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
KR1020217019436A Active KR102365961B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법

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KR1020137028251A Active KR102104401B1 (ko) 2011-03-29 2012-03-28 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법

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US (5) US9175290B2 (enExample)
EP (2) EP3674409A1 (enExample)
JP (6) JP6108628B2 (enExample)
KR (4) KR102481317B1 (enExample)
CN (3) CN113736782B (enExample)
AU (5) AU2012236700B2 (enExample)
BR (1) BR112013025006B1 (enExample)
CA (2) CA3217805A1 (enExample)
MX (3) MX360349B (enExample)
PH (2) PH12013501969B1 (enExample)
RU (1) RU2702501C2 (enExample)
SG (2) SG193923A1 (enExample)
WO (1) WO2012135246A2 (enExample)

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EP3674409A1 (en) 2011-03-29 2020-07-01 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of tmprss6 gene
ES2761343T3 (es) * 2011-11-07 2020-05-19 Ionis Pharmaceuticals Inc Modulación de la expresión de TMPRSS6
EP2994167B1 (en) 2013-05-06 2020-05-06 Alnylam Pharmaceuticals, Inc. Dosages and methods for delivering lipid formulated nucleic acid molecules
BR112015029276B1 (pt) * 2013-05-22 2022-07-12 Alnylam Pharmaceuticals, Inc Agente de irna fita dupla capaz de inibir a expressão de tmprss6, composição farmacêutica e uso dos mesmos
US10077444B2 (en) 2013-10-02 2018-09-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the LECT2 gene
IL316808A (en) 2014-08-20 2025-01-01 Alnylam Pharmaceuticals Inc Modified double-stranded RNA materials and their uses
JP6663428B2 (ja) * 2014-10-30 2020-03-11 アクセルロン ファーマ， インコーポレイテッド Ｇｄｆ１５ポリペプチドを使用する、赤血球を増加させるための方法および組成物
WO2016085852A1 (en) 2014-11-24 2016-06-02 Alnylam Pharmaceuticals, Inc. Tmprss6 irna compositions and methods of use thereof
JP6833705B2 (ja) * 2015-04-03 2021-02-24 アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． Ｔｍｐｒｓｓ６発現を調節するための化合物及び方法
MX2017012610A (es) 2015-04-08 2018-03-16 Alnylam Pharmaceuticals Inc Composiciones y metodos para inhibir la expresion del gen lect2.
CN110177544A (zh) 2016-11-29 2019-08-27 普尔泰克健康有限公司 用于递送治疗剂的外泌体
RS63887B1 (sr) * 2017-04-05 2023-02-28 Silence Therapeutics Gmbh Inhibicija tmprss6 posredovana rnk interferencijom
KR102834361B1 (ko) 2017-12-01 2025-07-17 쑤저우 리보 라이프 사이언스 컴퍼니, 리미티드 핵산, 이를 포함하는 조성물과 컨쥬게이트, 및 그의 제조 방법과 용도
JP7365052B2 (ja) 2017-12-01 2023-10-19 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
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