KR102269842B1 - Cosmetic composition comprising bifida ferment lysate and natural herbal extract - Google Patents

Abstract

The present invention relates to a cosmetic composition comprising a bifidobacteria-fermented product and a natural plant extract, and more particularly, to a cosmetic composition comprising a bifidobacteria-fermented product and a natural plant extract for enhancing skin elasticity, strengthening skin barrier and improving skin moisturizing effects by containing a bifidobacteria-fermented product; and natural plant extracts extracted from Brassica oleracea, Anthemis nobilis, Yucca brevifolia Engelm, Calendula, Scutellaria baicalensis, green tea, and rice.

Description

Cosmetic composition comprising bifida ferment lysate and natural herbal extract

The present invention relates to a cosmetic composition comprising a fermented bi-feeder and a natural plant extract, and more particularly, to a fermented bi-feeder; Cosmetics containing fermented bifida and natural plant extracts for skin elasticity improvement, skin barrier strengthening, skin moisturizing effect, including natural plant extracts extracted from broccoli, chamomile, yucca, calendula, gold, green tea and rice to the composition.

In general, as the skin ages, skin cells are damaged due to various contaminants, strong ultraviolet rays, stress, and nutritional deficiencies, and cell proliferation is not performed properly, leading to wrinkles, loss of elasticity and keratinization of the skin. As it develops, skin aging progresses.

Such skin aging is largely divided into intrinsic aging and extrinsic aging (Cosmetics & Toiletories, 111:31-37 (1996)).

Intrinsic aging is a natural aging phenomenon that occurs due to the gradual decline in the physiological functions of the skin with age. It is clinically characterized by a decrease in elasticity, rough skin texture, deep wrinkles, and pigmentation (Arch). Dermatol. 130:87-95 (1994)).

Exogenous aging refers to aging caused by extrinsic factors such as ultraviolet rays, reactive oxygen species, and stress.

Due to these factors, aging of the skin proceeds rapidly, and as a result, rough wrinkles are generated on the skin surface and elasticity is significantly reduced.

Several studies have been conducted to identify the mechanism of skin aging, and various causes of skin aging have been revealed. When the skin becomes dry due to a change in temperature, humidity, or wind, the physiological activity of the skin as a barrier to the outside decreases and aging is accelerated. When the skin is exposed to harmful active oxygen species or free radicals, it is caused by oxidation in the body. Lipid peroxide is produced and causes the modification of various proteins that make up the skin.

In addition, collagen and highly elastic elastin protein, which accounts for most of the skin dermis (about 70-80% of the total dry weight of the skin), are major proteins produced by fibroblasts. (Journal of the American academy of dermatology, 21:610-613 (1989)).

Collagen shows a quantitative decrease as the age increases and exposure to UV rays increases. Collagen is classified according to its morphology and structural characteristics. Among them, the most well-known types are types I, II, III and IV.

Collagen types I and III constitute a component of the intercellular matrix of the dermal layer, and collagen type IV is a major component of DEJ (Dermal Epidermal Junction). DEJ is located between the epidermal and dermal layers of the skin and controls the permeation and transport of substances between the two layers, controls the differentiation of adjacent skin cells, and maintains the firmness of the skin.

Collagen and elastin, which are the main structural components of the skin, are denatured or biosynthesized by natural or external stimuli, which accelerates skin aging.

Meanwhile, Probiotics is a compound word of Pro and Biotics. Pro means 'for' and 'Biotics' means life. The World Health Organization (WHO) defines probiotics as live microorganisms that have beneficial effects on health.

The history of the word probiotics is not very long, but it has been thousands of years since they entered human life. From cheese and yogurt to Korean kimchi and soybean paste, traditional foods that use fermentation to prevent spoilage and increase nutritional value also contain probiotics.

Among them, bifidobacteria and lactic acid bacteria are representative. These bifidobacteria and lactic acid bacteria are also used in the cosmetic field, mainly Streptococcus sp., Lactobacillus sp., Lactococcus sp., Leuconostoc sp. ), Bifidobacterium sp., etc. are used to directly ferment in a culture medium and filter or extract, etc., and active research is actively conducted on inoculating and fermenting the active material and filtering or extracting it. have.

In particular, Bifidobacterium, known as a beneficial bacteria with both usefulness and safety, is mainly active in the large intestine and normalizes the colonic flora, promotes white blood cell proliferation, produces vitamin B group, suppresses harmful bacteria in the large intestine, and has the vitality of surviving penicillin-based antibiotics. The fermented product is rich in protein, lactose, organic acids, vitamins and other minerals, and it increases the absorption of nutrients into the skin, removes old dead skin cells, has excellent moisturizing effect, clears the skin, stimulates immunity, and resists external stimuli. It induces reduction of skin troubles by controlling the activity of immune modulators in the body.

In addition, as a lactic acid bacterium, Lactobacillus pentosus ( Lactobacillus pentosus ) is a lactic acid bacterium belonging to the genus Lactobacillus, which resides in the intestines of humans, has antibacterial and antioxidant effects, and is a very useful strain that is also involved in anti-inflammatory and immunomodulatory functions. It is beneficially used in various industries such as food and cosmetics.

Looking at the prior art of using such fermented bifidobacteria and lactic acid bacteria in cosmetic compositions, Korean Patent No. 10-1849885 (registration date April 11, 2018), Korean-type lactic acid bacteria Lactobacillus pentosus GFC03 (Lactobacillus pentosus GFC03, deposited) No.: KCCM43226) strain and Lactobacillus bombicola IB3 (Lactobacillus bombicola IB3, Accession No.: KCCM 43227) A cosmetic composition for improving elasticity or moisturizing, characterized in that it contains whey obtained by fermenting milk with a strain has been developed.

In addition, Korean Patent Application Laid-Open No. 10-2019-0098603 (published on August 22, 2019) has improved moisturizing power containing microbial fermentation product, purified water, skin conditioning agent and glycerin, characterized in that it contains cosmetic composition As, the microbial fermentation is, Enterococcus faecalis (Enterococcus faecalis), Enterococcus faecium (Enterococcus faecium), Lactobacillus acidophilus (Lactobacillus acidophilus), Lactobacillus casei (Lactobacillus casei), Streptococcus cremo Streptococcus cremoris, Streptococcus lactis, Streptococcus thermophilus, Bifidobacterium longum, Bifidobacterium breve and Bifidobacterium breve A cosmetic composition with improved moisturizing power containing at least any one selected from the group consisting of Bifidobacterium bifidum is known.

In addition, in Korea Patent No. 10-2011240 (registration date August 08, 2019), the Lactobacillus paracasei SKB1192 (Lactobacillus paracasei SKB1192, accession number: KCCM12347P) strain for cosmetics having a cell lysate has a skin cell protection function against UV rays. As, a cosmetic composition having a skin cell protection function against UV rays using the Lactobacillus paracasei SKB1192 strain for cosmetics, characterized in that the cell lysate is a supernatant obtained by crushing the cells obtained from the strain culture medium and centrifuging is known. have.

In addition, Korean Patent No. 10-1975031 (registration date April 26, 2019) has a Bifidobacterium longum ATG-F5 (Bifidobacterium longum ATG-F5, Accession No.: KCTC13828BP) strain, characterized in that it has a skin barrier strengthening function. A cosmetic composition with skin barrier strengthening, skin dry relief, anti-inflammatory, anti-acne, antioxidant or anti-wrinkle effect, characterized in that it contains is known.

However, in the prior art of using the fermented bifidobacterium and lactic acid bacteria as described above in a cosmetic composition, the bifidobacterium or lactic acid bacteria obtained by using the bifidobacterium or lactic acid bacteria of the genus Bifidobacterium or Lactobacillus As a fermentation concentrate, it is mainly composed of cell lysate, but some of the cell components are known to cause skin and immune reactions.

That is, lipopolysaccharide (LPS, lipopolysaccharide) is present in the cell wall, but there is a problem that if this component is excessive, it may cause skin troubles such as atopy, erythema, and rash.

In addition, one of the problems when using lactic acid bacteria fermented product for skin protection in a cosmetic composition is that when cell lysate is applied to the skin, it is a protein source necessary for growth of the skin flora, so skin harmful bacteria use it as a growth factor If you do, there is a problem that the balance of the healthy skin microbiome is broken.

Accordingly, in order to minimize the protein components that can affect the human skin microbiome in the above-mentioned non-feeder fermented product or lactic acid bacterium fermented product, the present inventors are natural plants that are harmless to the skin and contain functional active ingredients to the skin. By mixing the extract with a fermented product of bifida or fermented lactic acid bacteria, a cosmetic composition comprising a fermented product of bifida and a natural plant extract for improving skin elasticity, strengthening the skin barrier, and improving skin moisturizing effect was developed and completed the present invention.

[Patent Document 001] Korean Patent 10-1849885 (Registration Date April 11, 2018) [Patent Document 002] Korean Patent Publication No. 10-2019-0098603 (published on August 22, 2019) [Patent Document 003] Korea Patent 10-2011240 (Registration Date August 08, 2019) [Patent Document 004] Korean Patent Registration 10-1975031 (Registration Date April 26, 2019)

The present invention provides a non-feeder fermented product to solve the above problems; Cosmetics containing fermented bifida and natural plant extracts for skin elasticity improvement, skin barrier strengthening, skin moisturizing effect, including natural plant extracts extracted from broccoli, chamomile, yucca, calendula, gold, green tea and rice It is a problem to be solved to provide a composition.

The present invention, in order to solve the above problems, a non-feeder fermented product; A cosmetic composition comprising a natural plant extract extracted from broccoli, chamomile, yucca, calendula, gold, green tea and rice is a means of solving the problem.

The bifeeder fermented product is Streptococcus thermophilus, Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus plantarum, (Lactococcus lactis), Lactobacillus lactis, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium breve and Bifidobacterium breve (Bifidobacterium bifidum) is a fermented product of at least one type of Bifidobacterium selected from the group consisting of Bifidobacterium bifidum as a means of solving the problem.

The bifido fermented product was obtained by adding 5 liters of 70% ethyl alcohol to 1 kg of ginseng powder, extracting under reflux at 85° C. for 3 hours, and then composing a natural medium containing the extract concentrated under reduced pressure, and inoculating the medium with the Bifidobacterium at 37° C. Fermentation while stirring and culturing for 3 days is a solution to the problem.

The content of the bi-feeder fermented product is included in an amount of 0.05 to 0.5 parts by weight based on 100 parts by weight of the total cosmetic composition as a means of solving the problem.

The natural plant extract is obtained by grinding 50 g of each of the broccoli, chamomile, yucca, calendula, gold, green tea and rice, and then mixing them, adding 70% ethyl alcohol to a total amount of 1 kg, and extracting for 48 hours while stirring at room temperature, followed by filtration and concentrated under reduced pressure as a means to solve the problem.

As a means of solving the problem, the content of the natural plant extract is included in an amount of 0.05 to 0.5 parts by weight based on 100 parts by weight of the total cosmetic composition.

The cosmetic composition includes an oil and fat component, a moisturizing agent, an emollient, a surfactant, an organic and inorganic pigment, an organic powder, an ultraviolet absorber, a preservative, a disinfectant, an antioxidant, a pH adjuster, an alcohol, a colorant, a fragrance, a blood circulation promoter, a cooling agent, It is a means of solving the problem to further include a compounding component selected from the limiting agent.

The formulation of the cosmetic composition is skin lotion, skin softener, skin toner, astringent, milk lotion, moisture lotion, nourishing lotion, massage cream, nourishing cream, moisture cream, hand cream, foot cream, neck cream, foundation, essence, pack , soap, cleansing foam, cleansing lotion, cleansing cream, body lotion, hair shampoo, hair treatment, hair conditioner and body cleanser as a means of solving the problem.

A cosmetic composition comprising a fermented product of lactic acid bacteria and a natural plant extract of the present invention, a fermented product of lactic acid bacteria; Contains natural plant extracts extracted from broccoli, chamomile, yucca, calendula, gold, green tea and rice, and has excellent effects to improve skin elasticity, strengthen skin barrier, and improve skin moisturizing effect.

1 is a view showing the skin barrier strengthening effect of the cosmetic composition of the present invention;
2 is a view showing the skin elasticity effect of the cosmetic composition of the present invention;

The present invention, a non-feeder fermented product; A cosmetic composition comprising a natural plant extract extracted from broccoli, chamomile, yucca, calendula, gold, green tea and rice is characterized by the technical composition.

The bifeeder fermented product is Streptococcus thermophilus, Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus plantarum, (Lactococcus lactis), Lactobacillus lactis, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium breve and Bifidobacterium breve (Bifidobacterium bifidum) It is characterized in that it is a fermented product of one or more kinds of Bifidobacterium selected from the technical composition.

The bifido fermented product was obtained by adding 5 liters of 70% ethyl alcohol to 1 kg of ginseng powder, extracting under reflux at 85° C. for 3 hours, and then composing a natural medium containing the extract concentrated under reduced pressure, and inoculating the medium with the Bifidobacterium at 37° C. It is characterized by the technical composition of fermentation while stirring and culturing for 3 days.

The content of the bi-feeder fermented product is characterized in that it is included in an amount of 0.05 to 0.5 parts by weight based on 100 parts by weight of the total cosmetic composition.

The natural plant extract is obtained by grinding 50 g of each of the broccoli, chamomile, yucca, calendula, gold, green tea and rice, and then mixing them, adding 70% ethyl alcohol to a total amount of 1 kg, and extracting for 48 hours while stirring at room temperature, followed by filtration and concentrated under reduced pressure.

The content of the natural plant extract is characterized in that it is contained in an amount of 0.05 to 0.5 parts by weight based on 100 parts by weight of the total cosmetic composition.

The cosmetic composition includes an oil and fat component, a moisturizing agent, an emollient, a surfactant, an organic and inorganic pigment, an organic powder, an ultraviolet absorber, a preservative, a disinfectant, an antioxidant, a pH adjuster, an alcohol, a colorant, a fragrance, a blood circulation promoter, a cooling agent, It is characterized in the technical configuration to further include a formulation component selected from the limiting agent.

The formulation of the cosmetic composition is skin lotion, skin softener, skin toner, astringent, milk lotion, moisture lotion, nourishing lotion, massage cream, nourishing cream, moisture cream, hand cream, foot cream, neck cream, foundation, essence, pack , soap, cleansing foam, cleansing lotion, cleansing cream, body lotion, hair shampoo, hair treatment, hair conditioner, and body cleanser selected from the group consisting of technical features.

Hereinafter, embodiments and/or drawings of the present invention will be described in detail so that those of ordinary skill in the art can easily carry out the present invention. However, the present invention may be embodied in many different forms, and is not limited to the embodiments and/or drawings described herein.

A cosmetic composition comprising a fermented bi-feeder and a natural plant extract of the present invention comprises: a fermented bi-feeder; Broccoli, chamomile, yucca, calendula, gold, natural plant extracts extracted from green tea and rice; composition including.

At this time, the bifeeder fermented product is Streptococcus thermophilus, Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus plantarum (Lactobacillus plantarum) Lactococcus lactis, Lactobacillus lactis, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium breve and Bifidobacterium A fermented product of at least one bifidobacterium selected from Bifidobacterium bifidum is used, and since the bifidobacterium is generally commonly used, a detailed description thereof will be omitted.

The bifido fermented product was prepared by adding 5 liters of 70% ethyl alcohol to 1 kg of ginseng powder, extracting under reflux for 3 hours at 85° C., and then using the concentrated extract under reduced pressure as a natural medium, inoculating the medium with the Bifidobacterium, and inoculating the medium at 37° C. It is obtained by fermenting while stirring and culturing for one day.

In particular, the content of the B-feeder fermented product is preferably included in an amount of 0.05 to 0.5 parts by weight based on 100 parts by weight of the total cosmetic composition. When it is included in an amount of 0.05 parts by weight or less, it is difficult to expect the skin function expected by the present invention, and 0.5 parts by weight When included in more than one part, there is a disadvantage that the protein component becomes excessive.

On the other hand, the natural plant extract is extracted from broccoli, chamomile, yucca, calendula, gold, green tea and rice.

Here, broccoli (Broccoli, Brassica oleracea) is a plant of the Brassica Brassicae family, which has dense green flower buds at the center and end of side branches. Broccoli is known as an excellent food containing vitamins such as vitamins C and K, water-soluble dietary fiber, and various inorganic salts, and is known to be effective in anti-cancer, anti-aging, gastrointestinal disease treatment, and adult disease prevention. used as an ingredient.

In addition, chamomile (Chamomile, Anthemis nobilis) is one of the herbs that have been used as folk remedies in the West for a long time and is known to be effective for skin infections and various skin diseases. In addition, it is known that when chamomile is treated on the exfoliated skin, it is effective not only in improving wound areas but also in moisturizing (Glovania HJ, Raulin C, et al. Wirkung der kaille in der Wundheilung-eine klinische Doppelblindstudie. Zeitschrift fur Hautkrankheiten, 1987; 62(17):1267-1271). In addition, it was confirmed that hamamelis and chamomile were effective in reducing UV-induced erythema (Korting HC, Schafer-Corting M, et al. Anti-inflammatory activity of hamamelis distillate applied topically to the skin. Eur J Clin Pharmacol (1993;44:315-318).

In addition, Yucca (Yucca brevifolia Engelm.Yucca schidigera Ortgies) is an evergreen shrub of the monocotyledonous liliaceae family of agave, native to North America, and one of the most important factors in the survival of Indian tribes living in the arid regions of northern Mexico and the southwestern United States. was one Yucca contains phosphorus, sodium, iron, zinc, calcium, manganese, copper, potassium, vitamins A, C, and vitamin B complex. It is also known to play a role in relieving, lowering blood pressure or cholesterol. It is a natural substance called yucasidegera, which is a substitute for steroids and non-steroidal anti-inflammatory drugs. It has antifungal and antiseptic effects and shows weak acidity. Therefore, in the present invention, It is used to show the effect for strengthening the skin barrier by using antifungal and antiseptic effects.

In addition, Calendula (Calendula arvensis L.) is a plant belonging to the genus Asteraceae, and its flower extract is the most widely used medicinal herb in the West as folk remedies. It has been used for skin problems, astringents, wound healing, and anti-inflammatory. In addition, the range of medical use is known to accelerate wound healing by increasing the synthesis of glycoprotein and collagen in the skin when used in surgical wounds and used for anti-inflammatory, astringent, antibacterial and antiviral properties. Its main ingredients include alpha-tocopherol, chlorogenic acid, lutin, and lycopene. In addition, the function of calendula flower extract as an antioxidant, a free radical inhibitor that causes aging and disease, has been reported.

In addition, gold (Scutellaria baicalensis George) belongs to the family Lamiaceae, is native to northern China on the East Asian continent, and is found in mountainous areas of Korea, geographically distributed in Siberia, Mongolia, China, and Manchuria. It is dried in spring or autumn, and the outer bark and rot inside are scraped off, washed in water and dried in the sun. It is used for diuresis, anti-inflammatory fever, congestive inflammation, and is also used for the treatment of blood pressure and arteriosclerosis. (Yucca brevifolia Engelm.Yucca schidigera Ortgies) is used to strengthen the skin barrier.

In addition, green tea is made from young eyes and young leaves of the perennial evergreen tea tree (Camellia sinensis O. Kuntze), and the effect of green tea is to prevent arteriosclerosis, expand blood vessels, promote blood circulation, and promote diuresis. It has astringent properties and aids digestion. Green tea extract is known to have anti-cancer effects, anti-aging effects, prevention of adult diseases, detoxification, prevention of tooth decay and removal of bad breath. The main ingredients are allantoin, catechin, chlorogenic acid, camperol. (kaempferol), myricetin, niacin, oleic acid, and thymol. In addition, green tea extract has been reported to have an effective antibacterial action against Prevotella intermedia, a bacterium that causes hormone-related periodontitis and promotes complex infection, and also functions as a natural preservative.

In addition, since ancient times, rice contains many nutrients and has been used for many purposes such as nutritional food and beauty. In addition, after drying and threshing the rice, the rice hulled off is called brown rice, and brown rice is divided into rice bran, rice germ and endosperm. Rice bran is rich in fat, protein, essential fatty acids, essential amino acids, vitamins, dietary fiber and minerals. The vitamins in this rice bran are myoinositol, choline, and niacin. It also contains B vitamins and tocopherols, an antioxidant that helps prevent cell aging and damage. Minerals include phosphorus, potassium, magnesium, and calcium, and rice bran contains protein, sitosterol, dietary fiber, etc., which are known to have an action to lower blood cholesterol, and γ-oryzanol. It is known to have blood circulation, skin metabolism promotion, whitening action and UV protection effect. Rice bran, which accounts for most of the nutritional components of rice, contains a large amount of calcium, magnesium, potassium and iron in addition to essential amino acids, tocopherol (vitamin E), vitamins B1, B2, and B6. It plays a role in transporting oxygen and nutrients to cells, excreting waste products and carbon dioxide, and inhibiting the increase of lipid peroxide, which prevents oxidation of body fat and weakens cell movement.

In the present invention, the natural plant extract is obtained by grinding 50 g of each of the broccoli, chamomile, yucca, calendula, gold, green tea and rice, and then mixing them, adding 70% ethyl alcohol to a total weight of 1 kg, and stirring at room temperature for 48 hours After extraction, filtration and concentration under reduced pressure are used.

At this time, the content of the natural plant extract is preferably included in an amount of 0.05 to 0.5 parts by weight with respect to 100 parts by weight of the total cosmetic composition, and when it is out of the above range, there is a risk of breaking the balance of skin protection function.

On the other hand, the cosmetic composition of the present invention may contain other ingredients that are usually formulated in the cosmetic composition. For example, oils and fats, moisturizing agents, emollients, surfactants, organic and inorganic pigments, organic powders, ultraviolet absorbers, preservatives, disinfectants, antioxidants, plant extracts, pH adjusters, alcohols, pigments, fragrances, blood circulation promoters, A cooling agent, a limiting agent, etc. are mentioned.

Examples of the fats and oils include ester fats and oils, hydrocarbon oils, silicone oils, fluorine oils, animal fats, and vegetable oils.

Examples of the ester-based oils and fats include glyceryl tri-ethylhexanoate, cetyl 2-ethylhexanoate, isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl stearate, octyl palmitate, isocetyl isostearate, stearate. Butyl arate, ethyl linoleate, isopropyl linoleate, ethyl oleate, isocetyl myristate, isostearyl myristate, isostearyl palmitate, octyldodecyl myristate, isocetyl isostearate, diethyl sebacate, Diisopropyl adipate, isoalkyl neopentanoate, tri(capryl, capric acid) glyceryl, trimethylolpropane tri2-ethylhexanoate, trimethylolpropane triisostearate, pentaeli tetra2-ethylhexanoate Slitol, cetyl caprylate, decyl laurate, hexyl laurate, decyl myristate, myristyl myristate, cetyl myristate, stearyl stearate, decyl oleate, cetyl ricinoleate, lauric acid Isostearyl, isotridecyl myristate, isocetyl palmitate, octyl stearate, isocetyl stearate, isodecyl oleate, octyldodecyl oleate, octyldodecyl linoleate, isostearate isopropyl, 2-ethylhexanoic acid Tostearyl, 2-ethyl stearyl hexanoate, hexyl isostearate, ethylene glycol dioctanoate, ethylene glycol dioleate, propylene glycol dicapric acid, di(caprylic acid, capric acid) propylene glycol, dicaprylic acid propylene glycol , neopentyl glycol dicapric acid, neopentyl glycol dioctanoate, glyceryl tricaprylate, glyceryl triundecyl acid, glyceryl triisopalmitate, glyceryl triisostearate, octyldodecyl neopentanoate, isose octanoate Tearyl, octyl isononanoate, hexyldecyl neodecanoate, octyldodecyl neodecanoate, isocetyl isostearate, isostearyl isostearate, octyldecyl isostearate, polyglycerol oleate ester, polyglycerol isostearic acid Ester, triisocetyl citrate, triisoalkyl citrate, triisooctyl citrate, lauryl lactate, myristyl lactate, cetyl lactate, octyldecyl lactate, triethyl citrate, acetyl triethyl citrate, acetyl tributyl citrate, trioctyl citrate, Diisostearyl malate, 2-ethylhexyl hydroxystearate, di2-ethylhexyl succinate, diisobutyl adipate, diisopropyl sebacate, di-sebacinate Octyl, cholesteryl stearate, cholesteryl isostearate, cholesteryl hydroxystearate, cholesteryl oleate, dihydrocholesteryl oleate, phytsteryl isostearate, phytsteryl oleate, 12-stearate Ester types, such as isocetyl alloyl hydroxy stearate, 12-stealoyl hydroxy stearate stearate, and 12-stealoyl hydroxy stearate isostearyl, etc. are mentioned.

Examples of the hydrocarbon-based oils and fats include hydrocarbon-based oils and fats such as squalene, liquid paraffin, alpha-olefin oligomer, isoparaffin, ceresin, paraffin, liquid isoparaffin, polybudene, microcrystalline wax, petrolatum, and the like.

Examples of the silicone-based oils and fats include polymethylsilicone, methylphenylsilicone, methylcyclopolysiloxane, octamethylpolysiloxane, decamethylpolysiloxane, dodecamethylcyclosiloxane, dimethylsiloxane/methylcetyloxysiloxane copolymer, dimethylsiloxane/methylstealloxysiloxane copolymer, Alkyl-modified silicone oil, amino-modified silicone oil, etc. are mentioned.

As said fluorine-type fats and oils, perfluoro polyether etc. are mentioned.

Examples of the animal or vegetable oil include avocado oil, almond oil, olive oil, sesame oil, rice bran oil, saffron oil, soybean oil, corn oil, rapeseed oil, passerine oil, palm kernel oil, palm oil, castor oil, sunflower oil, Grape seed oil, cottonseed oil, palm oil, kukui nut oil, wheat germ oil, rice germ oil, shea butter, colostrum colostrum, marker damia nut oil, meadow home oil, egg yolk oil, beef tallow, horse oil, mink oil, orange rafi oil, and animal or plant oils and fats such as jojoba oil, candelabra wax, carnauba wax, liquid lanolin, and hydrogenated castor oil.

Examples of the moisturizer include a water-soluble low molecular weight moisturizer, a fat-soluble molecular moisturizer, a water-soluble polymer, and a fat-soluble polymer. As the water-soluble low molecular weight moisturizer, serine, glutamine, sorbitol, mannitol, pyrrolidone-sodium carboxylate, glycerin, propylene glycol, 1,3-butylene glycol, ethylene glycol, polyethylene glycol B (polymerization degree n = 2 or more) , polypropylene glycol (polymerization degree n = 2 or more), polyglycerol B (polymerization degree n = 2 or more), lactic acid, lactic acid salt, and the like. Cholesterol, cholesterol ester, etc. are mentioned as said fat-soluble low molecular weight moisturizing agent. Examples of the water-soluble polymer include carboxyvinyl polymer, polyaspartate, tragacanth, xanthan gum, methyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, water-soluble chitin, chitosan, and dextrin. etc. Examples of the fat-soluble polymer include polyvinylpyrrolidone/eicosene copolymer, polyvinylpyrrolidone/hexadecene copolymer, nitrocellulose, dextrin fatty acid ester, and high molecular weight silicone.

As said emollient agent, long-chain acyl glutamic acid cholesteryl ester, hydroxystearic acid cholesteryl, 12-hydroxystearic acid, stearic acid, rosin acid, lanolin fatty acid cholesteryl ester, etc. are mentioned.

Nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, etc. are mentioned as said surfactant. Examples of the nonionic surfactant include self-emulsifying glycerin monostearate, propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerol fatty acid ester, sorbitan fatty acid ester, POE (polyoxyethylene), sorbitan fatty acid ester, POE sorbit. Fatty acid ester, POE glycerin fatty acid ester, POE alkyl ether, POE fatty acid ester, POE hydrogenated castor oil, POE castor oil, POEPOP (polyoxyethylene polyoxypropylene) copolymer, POEPOP alkyl ether, polyether-modified silicone, lauric acid alkanolamides, alkylamine oxides, hydrogenated soybean phospholipids, and the like. Examples of the anionic surfactant include fatty acid soap, alpha-acyl sulfonate, alkyl sulfonate, alkyl allyl sulfonate, alkyl naphthalene sulfonate, alkyl sulfate, POE alkyl ether sulfate, alkyl amide sulfate, alkyl phosphate, POE alkyl phosphate, Alkylamide phosphate, alkyloyl alkyl taurine salt, N-acyl amino acid salt, POE alkyl ether carboxylate, alkyl sulfosuccinate, alkyl sulfoacetate sodium, acylated hydrolyzed collagen peptide salt, perfluoroalkyl phosphate ester, etc. can be heard Examples of the cationic surfactant include alkyltrimethylammonium chloride, stearyltrimethylammonium chloride, stearyltrimethylammonium bromide, cetostearyltrimethylammonium chloride, distearyldimethylammonium chloride, stearyldimethylbenzylammonium chloride, and behenyltrimethylammonium bromide. , benzalkonium chloride, diethylaminoethylamide stearate, dimethylaminopropylamide stearate, and quaternary ammonium salts of lanolin derivatives. Examples of the amphoteric surfactant include carboxybetaine type, amidebetaine type, sulfobetaine type, hydroxysulfobetaine type, amidesulfobetaine type, phosphobetaine type, aminocarboxylate type, imidazoline derivative type, amideamine type, etc. of amphoteric surfactants, and the like.

Examples of the organic and inorganic pigments include silicic acid, silicic anhydride, magnesium silicate, talc, sericite, mica, kaolin, bengala, clay, bentonite, titanium-coated mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, oxide. inorganic pigments such as aluminum, calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, iron oxide, ultramarine, chromium oxide, chromium hydroxide, calamine, and complexes thereof; Polyamide, polyester, polypropylene, polystyrene, polyurethane, vinyl resin, urea resin, phenol resin, fluororesin, silicon resin, acrylic resin, melamine resin, epoxy resin, polycarbonate resin, divinylbenzene/styrene copolymer, and organic pigments such as silk powder, cellulose, CI pigment yellow and CI pigment orange, and composite pigments of these inorganic pigments and organic pigments.

Examples of the organic powder include metal soaps such as calcium stearate; alkyl phosphate metal salts such as sodium cetylate, zinc laurylate, and calcium laurylate; acylamino acid polyvalent metal salts such as calcium N-lauroyl-beta-alanine, zinc N-lauroyl-beta-alanine, and calcium N-lauroyl glycine; amidesulfonic acid polyvalent metal salts such as calcium N-lauroyl-taurine and calcium N-palmitoyl-taurine; N-epsilon-lauroyl-L-lysine, N-epsilon-palmitoylizine, N-alpha-paritoylolnithine, N-alpha-lauroylarginine, N-alpha-hydrogenated tallow fatty acid acylarginine, etc. N-acyl basic amino acid; N-acyl polypeptides, such as N-lauroyl glycyl glycine; alpha-amino fatty acids such as alpha-aminocaprylic acid and alpha-aminolauric acid; Polyethylene, polypropylene, nylon, polymethyl methacrylate, polystyrene, a divinylbenzene-styrene copolymer, ethylene tetrafluoride, etc. are mentioned.

Examples of the ultraviolet absorber include para-aminobenzoic acid, ethyl para-aminobenzoate, amyl para-aminobenzoate, octyl para-aminobenzoate, ethylene glycol salicylate, phenyl salicylate, octyl salicylate, benzyl salicylate, butylphenyl salicylate, homomentyl salicylate, cinnamic acid. Benzyl, para-methoxycinnamic acid-2-ethoxyethyl, para-methoxycinnamic acid octyl, dipara-methoxycinnamic acid mono-2-ethylhexane glyceryl, para-methoxycinnamic acid isopropyl, diisopropyl diisopropyl cinnamic acid ester mixture; Urocanic acid, ethyl urocanate, hydroxymethoxybenzophenone, hydroxymethoxybenzophenonesulfonic acid and its salts, dihydroxymethoxybenzophenone, dihydroxymethoxybenzophenonedisulfonate sodium, dihydroxybenzo Phenone, tetrahydroxybenzophenone, 4-tert-but-4'-methoxydibenzoylmethane, 2,4,6-trianilino-p-(carbo-2'-ethylhexyl-1'-oxy)- 1,3,5-triazine, 2-(2-hydroxy-5-methylphenyl) benzotriazole, etc. are mentioned.

Examples of the disinfectant include hinokitiol, triclosan, trichlorohydroxydiphenyl ether, chlorhexidine gluconate, phenoxyethanol, resorcin, isopropylmethylphenol, azulene, salicylic acid, zincphyllithione, benzalkonium chloride, Photosensitizer No. 301, mononitroguaial sodium, undecyrenic acid, etc. are mentioned.

Examples of the antioxidant include butylhydroxyanisole, propyl gallic acid, and ellisorbic acid.

Examples of the pH adjuster include citric acid, sodium citrate, malic acid, sodium malate, fmalic acid, sodium fumarate, succinic acid, sodium succinate, sodium hydroxide, sodium monohydrogen phosphate, and the like.

As said alcohol, higher alcohols, such as cetyl alcohol, are mentioned.

In addition, the compounding component which may be added other than this is not limited to this, Moreover, any said component can be mix|blended within the range which does not impair the objective and effect of this invention.

In addition, the cosmetic composition of the present invention may take the form of a solution, an emulsion, a viscous mixture, and the like. That is, the components included in the cosmetic composition of the present invention may include components commonly used in cosmetic compositions as active ingredients, for example, conventional adjuvants such as stabilizers, solubilizers, vitamins, pigments and fragrances, and carrier.

The cosmetic composition of the present invention may be prepared in any formulation conventionally prepared in the art, for example, skin lotion, skin softener, skin toner, astringent, milk lotion, moisture lotion, nourishing lotion, massage cream, nourishing cream , Moisture Cream, Hand Cream, Foot Cream, Neck Cream, Foundation, Essence, Pack, Soap, Cleansing Foam, Cleansing Lotion, Cleansing Cream, Body Lotion, Hair Shampoo, Hair Treatment, Hair Conditioner, and Body Cleanser can be

[Production of Bfeeder Fermented Product]

5 L of 70% ethyl alcohol was added to 1 kg of ginseng powder, extracted under reflux at 85° C. for 3 hours, and concentrated under reduced pressure to prepare a ginseng powder extract, and a natural medium containing it was prepared as shown in Table 1 below.

ingredient Content (g) Radish 0.7 sodium chloride 0.5 Yeast 5.0 Glucose 10.0 Ginseng Powder Extract 10.0 Distilled water 73.8 total 100

3 g of Bifidobacterium longum HY8004 lactic acid bacteria powder (Bifidobacterium longum HY8004) (Korea Yakult Co., Ltd.) was inoculated into the medium, and fermented while stirring and culturing at 37° C. for 3 days to prepare a fermented Bifidobacterium.

[Production of natural plant extract]

Broccoli, chamomile, yucca, calendula, gold, green tea and rice are ground 50 g each, mixed, and 70% ethyl alcohol is added to make a total amount of 1 kg, extracted for 48 hours while stirring at room temperature, filtered and concentrated under reduced pressure to natural plants An extract was prepared.

[Preparation of the cosmetic composition of the present invention]

As shown in Table 2 below, a cosmetic composition comprising the fermented bi-feeder of the present invention and a natural plant extract was prepared.

composition Weight (g) Purified water 78.33 glycerin 13.70 capric triglyceride 3.00 olive oil 1.20 Hydrogenated Lecithin 1.05 1,2 Hexanediol 0.95 shea butter 0.60 squalane 0.30 allantoin 0.20 xanthan gum 0.20 cholesterol 0.08 Bfeeder Fermented Product 0.10 natural plant extract 0.10 dipotassium glycyrrhizate 0.05 Ceramide NP 0.04 Acetylphytosphingosine 0.04 Butylene Glycol 0.03 Phytosphingosine 0.03 Total 100.00

[Measurement of skin moisturizing effect]

Moisturizing effect was confirmed in 10-20s 20 people suffering from dry skin diseases such as psoriasis. Twenty people were divided into four groups and the cosmetic composition of the present invention was applied to the skin area twice daily for 2 weeks, respectively. Then, each participant's subjective evaluation of the skin condition was collected and shown in [Table 3].

As evaluation items, marked improvement, improvement, moderate, and worsening were used. As shown in [Table 3], it can be seen that 90% or more of the skin condition is improved when the cosmetic composition of the present invention is used, which is considered to be the effect of the fermented bifida and natural plant extracts on the cosmetic composition.

Response rate (%) significantly improved Improving usually worse 20 70 10 0

[Measurement of skin barrier strengthening effect]

As a clinical indicator to evaluate the skin barrier function, TEWL (transepidermal water loss) was measured. As a measurement method, it was measured by tape stripping, and TEWL (transdermal moisture loss) before and after tape stripping was measured by repeatedly stripping using cellophane tape, and the results are shown in [FIG. 1].

As shown in [Fig. 1], it can be seen that the cosmetic composition of the present invention significantly reduces TEWL (transdermal moisture loss).

[Measurement of skin elasticity effect]

After applying the cosmetic composition of the present invention to the eyes and face every day for 4 weeks to the subjects, the elasticity improvement effect was confirmed. Elasticity was measured using a Cutometer (MPA 580, Courage and Khazaka Electronic Co., Germany) at a distance of 3 cm from the eye area. The evaluation was performed three times, and the average of the three values was used. The higher the value, the better the skin elasticity. In this test, values were measured after 2 weeks of use and 4 weeks after use, and the measurement coefficient is an arbitrary unit (A.U.). In addition, the result obtained in this way was confirmed by calculating the elasticity improvement rate (%).

As shown in the test results [Fig. 2], it can be seen that the skin elasticity is significantly increased while the cosmetic composition of the present invention is applied for 4 weeks.

The above description is merely illustrative of the technical idea of the present invention, and various modifications and variations will be possible without departing from the essential characteristics of the present invention by those skilled in the art to which the present invention pertains. Accordingly, the embodiments and/or drawings disclosed in the present invention are not intended to limit the technical spirit of the present invention, but to explain, and the scope of the technical spirit of the present invention is not limited by these embodiments and/or drawings. . The protection scope of the present invention should be construed by the following claims, and all technical ideas within the equivalent range should be construed as being included in the scope of the present invention.

Claims (8)

Streptococcus thermophilus, Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactococcus lactis selected from Lactobacillus lactis, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium breve and Bifidobacterium bifidum a bifido fermented product, which is a fermented product of at least one bifidobacterium; A cosmetic composition comprising a fermented bifeeder product and a natural plant extract comprising; broccoli, chamomile, yucca, calendula, gold, green tea and natural plant extracts extracted from rice
delete According to claim 1,
The bifido fermented product was obtained by adding 5 liters of 70% ethyl alcohol to 1 kg of ginseng powder, extracting under reflux at 85° C. for 3 hours, and then composing a natural medium containing the extract concentrated under reduced pressure, and inoculating the medium with the Bifidobacterium at 37° C. A cosmetic composition comprising a bifeeder fermented product and a natural plant extract, characterized in that it was fermented while stirring and culturing for 3 days in
According to claim 1,
The content of the fermented bi-feeder is a cosmetic composition comprising a fermented bi-feeder and a natural plant extract, characterized in that it is included in an amount of 0.05 to 0.5 parts by weight based on 100 parts by weight of the total cosmetic composition.
According to claim 1,
The natural plant extract is obtained by pulverizing 50 g of each of the broccoli, chamomile, yucca, calendula, gold, green tea and rice, mixing, adding 70% ethyl alcohol to a total amount of 1 kg, and extracting for 48 hours while stirring at room temperature, followed by filtration and a cosmetic composition comprising a bifeeder fermented product and a natural plant extract, characterized in that it is concentrated under reduced pressure
According to claim 1,
The content of the natural plant extract is a cosmetic composition comprising a fermented bifeed product and a natural plant extract, characterized in that it is included in an amount of 0.05 to 0.5 parts by weight based on 100 parts by weight of the total cosmetic composition.
7. The method of any one of claims 1, 3 to 6,
The cosmetic composition includes an oil and fat component, a moisturizer, an emollient, a surfactant, an organic and inorganic pigment, an organic powder, an ultraviolet absorber, a preservative, a disinfectant, an antioxidant, a pH adjuster, an alcohol, a colorant, a fragrance, a blood circulation promoter, a cooling agent, Cosmetic composition comprising fermented bi-feeder and natural plant extract, characterized in that it further comprises a combination component selected from limiting agents
8. The method of claim 7,
The formulation of the cosmetic composition is skin lotion, skin softener, skin toner, astringent, milk lotion, moisture lotion, nourishing lotion, massage cream, nourishing cream, moisture cream, hand cream, foot cream, neck cream, foundation, essence, pack. , soap, cleansing foam, cleansing lotion, cleansing cream, body lotion, hair shampoo, hair treatment, hair conditioner and body cleanser, characterized in that it is selected from the group consisting of a cosmetic composition comprising a fermented product and natural plant extract

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