KR100708236B1 - Cosmetic composition comprising the flower extract of Camellia japonica L. showing astringent activity - Google Patents

Abstract

The present invention relates to a cosmetic composition containing a flower extract of Camellia japonica L. Camellia japonica L. , specifically, the Camellia extract of the present invention has an effect of inhibiting sebum hypersecretion by pore contraction using hemoglobin protein and albumin protein, It can be usefully used as a convergent cosmetic composition for sebum over secretion and oily skin relief by confirming the excellent skin oil reduction effect in the skin coating test.

Camellia, camellia, pore shrinkage, sebum oversecretion, oil, astringent cosmetic composition

Description

 Cosmetic composition containing Camellia extract with skin astringent effect

1 is a diagram showing a standard curve measuring the polyphenol content of the camellia extract.

The present invention relates to a cosmetic composition containing a camellia extract as an active ingredient.

Camellia Japonica L. is an evergreen broad-leaved arboreous tree of the genus Camellia japonica , with many twigs on white stems, forming a long oval or hemispherical tree. have. It is 5-12cm long and 3-7cm wide, and the surface is dark green. The flower is recognized as 5 petals of bright red or white, generally reddish purple. Blooming from November to March of next year, the seeds mature at the end of October.

These camellia flowers contain tannins, camelliins, and leucocyanidins. Seeds contain 66% oil, the main component being glycerides of oleic acid. In addition, glycosides camellia (C ₁₈ H ₃₄ O ₇ ) and camellia saponin (C ₅₈ H ₉₂ O ₂₅ ) are present in the seed (Science Encyclopedia , Ingredients and Applications of Herbs , 1999). Camelin has a strong heart action, Camellia saponin is known to be known for hemolytic action, camellia oil is used as a base oily ointment. In addition, the Camellia flower (山 茶花) uses red flowers as a hemostatic agent for hemostasis and intestinal bleeding in folk medicine, and it is taken as powder and taken together with the juice of Donguri and Ginger and liquor. al., Shoyakugaku Zasshi , 38 (3) , pp.263-264, 1984), inhibiting tartar formation (Yoshikawa et al., Chem. Pharm. Bull . 42 (3) , p.742, 1994), alcohol absorption Inhibition (Mori and Nishimiya, JP-A 63-303910 , 12, Dec., 1988), whitening action (Sakata et al., Mem. Fac. Agr. Kagoshima Univ. , 17 , pp . 79-94, 1981) Biological activity such as has been reported. In addition, Korean Patent Publication No. 88-02026 uses edible oil processing method using camellia seeds, and Korean Patent Registration No. 0290591 describes hair cosmetic composition using camellia oil, and Korean Patent Registration No. 0337148 uses deodorant. It has applied for an invention relating to. However, if you look at the prior patent data related to camellia flowers, such as camellia seeds, camellia trees, etc., there are currently no cosmetic applications using camellia flowers worldwide.

In addition, the Camellia flower used in the present invention is a material that has been used in herbal medicine for a long time, has been confirmed to be safe for the human body even when ingested in the body, and is an extremely safe natural raw material with little irritation to the skin and mucous membranes.

In general, cosmetics are used to make a person's body clean, beautiful, and more attractive, or they can be applied, sprayed, or otherwise used on the body to keep skin and hair healthy. It refers to a thing with little effect on the human body. That is, cosmetics are articles which are used to maintain beauty by properly blending or spraying various ingredients on the body, or by spraying to keep the body and hair clean and healthy. Products used for this purpose are commercially available in various forms, such as lotion, milky lotion, cream, essence, foundation.

Regardless of the various types of cosmetics, cosmetics are pursuing many functions such as moisturizing, whitening, cleansing, and convergence to satisfy consumers' preferences. The double convergence effect is to adjust the skin condition to the original appearance as if to adjust the piano and to have a refreshing feeling, it is to pull the skin protein temporarily to suppress the excessive sebum or sweat secretion. Converging action over 30s, shrinking pores enlarged in the face area to shrink excessive pores or pores to feel elasticity and suppleness on the skin.

Convergence on the skin is divided into two categories, chemical and physical. Chemical convergence refers to the temporary contraction of sweat glands and pores by substances that bind protein, such as tannins. On the other hand, physical astringent is used to cool water to the skin, or by lowering the temperature of the skin to the volatilization of ethanol refers to temporarily contract in the glands and follicles (habyeongjo, hwajangpumhak, sumunsa, p.83, 1999).

When astringents are applied to the skin, the effect on the skin is local. The effect of astringents is on the straightening of the hair, on tight skin (at least the skin feels tight), temporary contraction of pores or pores, inhibition of sweating, relief of oily skin, blood coagulation of wounds, wound healing and tissue growth Promotion.

Raw materials exhibiting this convergence effect include witch hazel extract, zinc paraphenolsulfonic acid, tannin, tannic acid, etc., but most of the raw materials exhibiting convergence effect are dark in color and poor in stability, so they can be used in an amount that exhibits actual convergence effect. There is no situation. Among them, witch hazel extract has excellent color and stability, but the most important convergence effect is negligible. In addition, parasulfonic acid zinc, tannin, tannic acid and the like is excellent in effect and solubility in water, but the amount of use is limited because of concerns about skin irritation.

Recently, plant extracts having astringent effects have been developed as astringents in accordance with the trend of natural cosmetics. Most of these plant extracts are characterized by containing tannin.

Therefore, the present inventors conducted extensive research on ancient books and folk remedies to develop extracts having excellent astringent effects on plants native to nature, and have excellent pore contraction effects and sebum on camellia flowers. Confirming the secretion inhibitory effect was completed the present invention.

An object of the present invention is to provide a cosmetic composition comprising a Camellia japonica L. flower extract excellent in sebum hypersecretion effect by pores contraction, skin oil reduction effect in the skin coating test.

In order to achieve the above object, the present invention provides a cosmetic composition containing an extract of Camellia japonica (camellia japonica L .; hereinafter called camellia) having the effect of pore contraction, sebum oversecretion and skin oil reduction effect as an active ingredient do.

The extract is extracted with one or more solvents selected from the group consisting of C1 to C4 lower alcohols, glycerin, butylene glycol, propylene glycol, hydrous ethanol, hydrous propylene glycol, hydrous butylene glycol, including purified water, methanol, ethanol, and the like. Means a cosmetic composition.

Hereinafter, the present invention will be described in detail.

Camellia extract of the present invention is a dried camellia flower of about 1 to 40 times the weight of the weight, preferably about 15 to 25 times the volume of water, lower alcohol of 1 to 4 carbon atoms or about 1: 0.1 to 1:10, Preferably a mixed solvent having a mixing ratio of 1: 0.2 to 1: 3, or a hydrous butylene glycol, a hydrous propylene glycol and a hydrous ethanol, preferably 10 to 120 캜, preferably 40 to 95 캜, with hydrous ethanol About 0.5 hours to 10 days at temperature, preferably 3 hours to 2 days extraction method such as cold sewage extraction, hot water extraction, ultrasonic extraction, reflux cooling extraction, preferably by reflux cooling extraction, or 5 to 50 ℃ After extracting, preferably by dipping for 1 to 15 days at 10 to 37 ℃, the extract is filtered after cooling, and the filtrate is dried with a rotary pressure reducer to obtain the camellia extract of the present invention.

The extract of the present invention comprises 0.001 to 10% by weight, preferably 0.1 to 8% by weight, most preferably 0.5 to 5% by weight, based on the total skin oil content, with respect to the total weight of the composition. It is more preferable to choose.

As a result of checking sebum hypersecretion effect by the pores contraction using hemoglobin protein and albumin protein of the camellia flower extract obtained by the extraction method, and skin oil reduction effect in the skin application test, sebum oversecretion and oily skin improvement It was confirmed that it can be used as a convergent cosmetic composition for.

Camellia extract of the present invention can be used in a variety of cosmetics and cleansing agents for sebum over secretion inhibition and oily skin improvement effect. Examples of products to which the present composition can be added include cosmetics such as various creams, lotions, skins, and the like, cleansing agents, face washes, soaps, treatments, and essences.

Cosmetics of the present invention comprises a composition selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, polymer peptides, polymer polysaccharides, sphingolipids and seaweed extract.

The water-soluble vitamin may be any compound that can be incorporated into cosmetics, but preferably vitamin B1, vitamin B2, vitamin B6, pyridoxine, pyridoxine, vitamin B12, pantothenic acid, nicotinic acid, nicotinic acid amide, folic acid, vitamin C, vitamin H, and the like. And salts thereof (thiamine hydrochloride, sodium ascorbate salt, etc.) and derivatives (ascorbic acid-2-sodium phosphate salt, ascorbic acid-2-magnesium phosphate salt, etc.) can also be used in the present invention. Included in The water-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification from microorganism culture, enzyme or chemical synthesis.

The oil-soluble vitamin may be any compound that can be incorporated into cosmetics, but preferably vitamin A, carotene, vitamin D2, vitamin D3, vitamin E (d1-alpha tocopherol, d-alpha tocopherol, d-alpha tocopherol), and the like. And derivatives thereof (ascorbic palmitate, ascorbic stearate, ascorbic acid dipalmitate, dl-alpha tocopherol acetate, dl-alpha tocopherolvitamin E, DL-pantothenyl alcohol, D-pantothenyl alcohol, pantothenyl ethyl) Ethers, etc.) are also included in the oil-soluble vitamins used in the present invention. Oil-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification of microorganism culture, enzyme or chemical synthesis.

The polymer peptide may be any compound as long as it can be incorporated into cosmetics. Preferably, collagen, hydrolyzed collagen, gelatin, elastin, hydrolyzed elastin, keratin, and the like can be given. Polymeric peptides can be purified and obtained by conventional methods such as purification from microbial cultures, enzymatic methods or chemical synthesis methods, or can be purified and used from natural products such as dermis and pig silk such as pigs and cattle.

The polymer polysaccharide may be any compound as long as it can be blended into cosmetics. Preferably, hydroxyethyl cellulose, xanthan gum, sodium hyaluronate, chondroitin sulfate or a salt thereof (sodium salt, etc.) may be mentioned. For example, chondroitin sulfate or its salt, etc. can be normally purified from a mammal or fish.

The sphingolipid may be any compound as long as it can be blended into cosmetics. Preferably, ceramide, phytosphingosine, sphingosaccharide lipid, etc. may be mentioned. Sphingo lipids can usually be purified from mammals, fish, shellfish, yeasts or plants by conventional methods or obtained by chemical synthesis.

The seaweed extract may be any compound as long as it can be blended into cosmetics. Preferably, the seaweed extract may include brown algae extract, red algae extract, green algae extract, and the like. Also, calginine, arginic acid, sodium arginate, Potassium arginate and the like are also included in the seaweed extract used in the present invention. Seaweed extract can be obtained by purification from seaweed by conventional methods.

In addition to the said essential component, you may mix | blend the cosmetics of this invention with the other components normally mix | blended with cosmetics as needed.

Other components that may be added include fats and oils, moisturizers, emollients, surfactants, organic and inorganic pigments, organic powders, ultraviolet absorbers, preservatives, fungicides, antioxidants, plant extracts, pH adjusters, alcohols, pigments, flavorings, Blood circulation accelerators, cooling agents, restriction agents, purified water and the like.

Examples of the fat or oil component include ester fats, hydrocarbon fats, silicone fats, fluorine fats, animal fats, and vegetable fats and oils.

As ester fats and oils, glyceryl tri2-ethylhexanoate, cetyl 2-ethylhexanoate, isopropyl myristate, butyl mystinate, isopropyl palmitate, ethyl stearate, octyl palmitate, isocetyl isostearate, and stearic acid Butyl, ethyl linoleate, isopropyl linoleate, ethyl oleate, isocetyl acid isocetyl, isostyl acid isostearyl, isostaryl palmitate, octylate acid octyldodecyl, isostearic acid isetyl, diethyl sebacate, adipine Acid isopropyl, isoalkyl neopentane, tri (capryl, capric acid) glyceryl, trimethyl ethyl trimethylol propane, triisostearic acid trimethylol propane, tetra 2-ethylhexanoic penta erythritol Cetyl caprylate, lauric acid decyl, hexyl laurate, decyl myristin, myristin acid myristyl, myritic acid cetyl, stearyl stearate, decyl oleate, rininooleic acid , Isostearyl laurate, isotridecyl myristin, isocetyl palmitate, octyl stearate, isocetyl stearate, isodecate oleate, octylate decyl oleate, octyl dodecyl linoleate, isopropyl isopropyl acid, 2 -Cetostearyl ethylhexanoate, stearyl 2-ethylhexanoate, hexyl isostearate, ethylene glycol dioctanoate, ethylene glycol dioleate, propylene glycol dicapric acid, propylene glycol dicacapate, capric acid Propylene glycol, dicapric acid neopentyl glycol, dioctanoate neopentyl glycol, tricaprylic acid glyceryl, triundecyl glyceryl, triisopalmitinate glyceryl, triisostearate glyceryl, neopentane dodecyl Isostearyl octanoate, octyl isononanoate, hexyldecyl neodecanoate, octyldodecyl neodecanoate, isocetyl isostearate, isostearyl isostearate, Sothete octylate, polyglycerol oleate, polyglycerine isostearate, triisocetyl citrate, triisoalkyl citrate, triisooctyl citrate, lauryl lactate, myritic lactate, octyl lactate, octyl lactate Ethyl, acetyl triethyl citrate, acetyl tributyl citrate, trioctyl citrate, diisostearyl malic acid, 2-ethylhexyl hydroxystearate, di2-ethylhexyl succinate, diisobutyl adipicate, diisopropyl sebacinate, Dioctyl sebacate, cholesteryl stearate, cholesteryl isostearate, cholesteryl hydroxystearate, cholesteryl oleate, dihydrocholesteryl oleate, physteryl isostearate, phytic oleate, 12-Steloylhydroxystearate isocetyl, 12-Steloylhydroxystearate stearyl, 12-steal One hydroxy stearic acid and the like esters such as cetearyl source.

Hydrocarbon-based fats and oils, such as squalene, a liquid paraffin, alpha-olefin oligomer, isoparaffin, ceresin, paraffin, a liquid isoparaffin, polybutene, microcrystal wax, and a vaseline, etc. are mentioned as a hydrocarbon-type fats and oils.

Examples of the silicone-based oils and fats include polymethylsilicone, methylphenylsilicone, methylcyclopolysiloxane, octamethylpolysiloxane, decamethylpolysiloxane, dodecamethylcyclosiloxane, dimethylsiloxane, methylcetyloxysiloxane copolymer, dimethylsiloxane and methylsteoxysiloxane copolymer, and alkyl. Modified silicone oil, amino modified silicone oil and the like.

Perfluoro polyether etc. are mentioned as fluorine-based fats and oils.

As animal or vegetable fats and oils, avocado oil, almond oil, olive oil, sesame oil, rice bran oil, soybean oil, soybean oil, corn oil, rapeseed oil, almond oil, palm kernel oil, palm oil, castor oil, sunflower oil, grape seed oil , Cottonseed oil, Palm oil, Cucumber nut oil, Wheat germ oil, Rice germ oil, Shea butter, Walnut colostrum oil, Marker demia nut oil, Meadow home oil, Egg yolk oil, Uji, Horse oil, Mink oil, Orange rape oil, Jojoba oil And animal or plant fats and oils such as candeler wax, carnava wax, liquid lanolin and hardened castor oil.

Examples of the moisturizing agent include a water-soluble low molecular moisturizer, a fat-soluble molecular moisturizer, a water-soluble polymer, and a fat-soluble polymer.

Water-soluble low molecular humectants include serine, glutamine, sorbitol, mannitol, pyrrolidone-sodium carboxylate, glycerin, propylene glycol, 1,3-butylene glycol, ethylene glycol, polyethylene glycol B (polymerization degree n = 2 or more), polypropylene Glycol (polymerization degree n = 2 or more), polyglycerol B (polymerization degree n = 2 or more), lactic acid, lactic acid salt, etc. are mentioned.

Examples of the fat-soluble low molecular humectants include cholesterol and cholesterol esters.

Examples of the water-soluble polymer include carboxyvinyl polymer, polyasparaginate, tragacanth, xanthan gum, methyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, water soluble chitin, chitosan, and dextrin. Can be.

Examples of the fat-soluble polymers include polyvinylpyrrolidone-eicosene copolymers, polyvinylpyrrolidone-hexadecene copolymers, nitrocellulose, dextrin fatty acid esters, polymer silicones, and the like.

Examples of the emollient include long-chain acyl glutamic acid cholesteryl esters, hydroxy stearic acid cholesterol, 12-hydroxystearic acid, stearic acid, rosin acid, lanolin fatty acid cholesteryl esters, and the like.

As surfactant, nonionic surfactant, anionic surfactant, cationic surfactant, amphoteric surfactant, etc. are mentioned.

As the nonionic surfactant, self-emulsifying glycerin monostearate, propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerol fatty acid ester, sorbitan fatty acid ester, POE (polyoxyethylene) sorbitan fatty acid ester, POE sorbitan fatty acid ester, POE Glycerin fatty acid ester, POE alkyl ether, POE fatty acid ester, POE hardened castor oil, POE castor oil, POE / POP (polyoxyethylene / polyoxypropylene) copolymer, POE / POP alkyl ether, polyether modified silicone, lauric acid Alkanolamide, alkylamine oxide, hydrogenated soybean phospholipid, etc. are mentioned.

Anionic surfactants include fatty acid soaps, alpha-acyl sulfonates, alkyl sulfonates, alkyl allyl sulfonates, alkyl naphthalene sulfonates, alkyl sulfates, POE alkyl ether sulfates, alkylamide sulfates, alkyl phosphates, POE alkylphosphates, and alkylamides. Phosphates, alkyloylalkyltaurine salts, N-acylamino acid salts, POE alkyl ether carboxylate salts, alkyl sulfosuccinate salts, sodium alkyl sulfo acetates, acylated hydrolyzed collagen peptide salts, perfluoroalkyl phosphate esters, and the like. have.

As cationic surfactant, alkyl trimethylammonium chloride, stearyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, cetostearyl trimethyl ammonium chloride, distearyl dimethyl ammonium chloride, stearyl dimethyl benzyl ammonium bromide, behenyl trimethyl ammonium chloride, chloride Benzalkonium, diethylaminoethyl stearate, dimethylaminopropyl stearate, lanolin derivatives, quaternary ammonium salts, and the like.

Examples of amphoteric surfactants include the carboxybetaine type, the amide betain type, the sulfobetain type, the hydroxysulfobetain type, the amide sulfobetain type, the phosphobetaine type, the aminocarboxylate type, the imidazoline derivative type, and the amideamine type. An amphoteric surfactant etc. are mentioned.

Organic and inorganic pigments include silicic acid, silicic anhydride, magnesium silicate, talc, sericite, mica, kaolin, bengala, clay, bentonite, titanium film mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, aluminum oxide Inorganic pigments such as calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, iron oxide, ultramarine blue, chromium oxide, chromium hydroxide, calamine and composites thereof; Polyamide, polyester, polypropylene, polystyrene, polyurethane, vinyl resin, urea resin, phenol resin, fluorine resin, silicon resin, acrylic resin, melamine resin, epoxy resin, polycarbonate resin, divinylbenzene, styrene copolymer, Organic pigments such as silk powder, cellulose, CI pigment yellow, CI pigment orange, and composite pigments of these inorganic pigments and organic pigments;

As organic powder, Metal soaps, such as a calcium stearate; Alkyl phosphate metal salts such as sodium cetylinate, zinc lauryl acid and calcium laurate; Acylamino acid polyvalent metal salts such as N-lauroyl-beta-alanine calcium, N-lauroyl-beta-alanine zinc, and N-lauroylglycine calcium; Amide sulfonic acid polyvalent metal salts, such as N-lauroyl-taurine calcium and N-palmitoyl-taurine calcium; N-epsilon-lauroyl-L-lysine, N-epsilon-palmitolysine, N-alpha-paratoylolnitine, N-alpha-lauroyl arginine, N-alpha-cured fatty acid acyl arginine N-acyl basic amino acid; N-acyl polypeptides, such as N-lauroyl glycyl glycine; Alpha-amino fatty acids such as alpha-aminocaprylic acid and alpha-aminolauric acid; Polyethylene, polypropylene, nylon, polymethyl methacrylate, polystyrene, divinylbenzene-styrene copolymer, ethylene tetrafluoride and the like.

Examples of the ultraviolet absorber include paraaminobenzoic acid, ethyl paraaminobenzoate, amyl paraaminobenzoic acid, octyl paraaminobenzoate, ethylene glycol salicylate, phenyl salicylate, octyl salicylate, benzyl salicylate, butylphenyl salicylate, homomentyl salicylic acid and benzyl cinnamic acid. , Paramethoxy cinnamic acid-2-ethoxyethyl, paramethoxy cinnamic acid octyl, diparamethoxy cinnamic acid mono-2-ethylhexaneglyceryl, paramethoxy cinnamic acid isopropyl, diisopropyl diisopropyl cinnamic acid ester mixture, wuro Canonic acid, ethyl urokanoate, hydroxymethoxybenzophenone, hydroxymethoxybenzophenonesulfonic acid and salts thereof, dihydroxymethoxybenzophenone, dihydroxymethoxybenzophenone sodium sulfonate, dihydroxybenzophenone , Tetrahydroxybenzophenone, 4- tert -butyl-4'-methoxydibenzoylmethane, 2,4,6-trianilino- p- (carbo-2'-ethylhexyl-1'-oxy) -1 , 3,5-triazine, 2- (2-hi And the like can be mentioned hydroxy-5-methylphenyl) benzotriazole.

As fungicides, hinokithiol, trichloric acid, trichlorohydroxydiphenyl ether, chlorhexidine gluconate, phenoxyethanol, resorcin, isopropylmethylphenol, azulene, salicylic acid, ginxitlionone, benzalkonium chloride, photosensitive Sodium No. 301, sodium mononitroguicol, undecylenic acid, and the like.

Examples of the antioxidant include butylhydroxyanisole, propyl gallic acid, and erythorbic acid.

Examples of the pH adjuster include citric acid, sodium citrate, malic acid, sodium malate, fmaric acid, sodium pmarate, succinic acid, sodium succinate, sodium hydroxide, sodium dihydrogen phosphate, and the like.

Examples of the alcohol include higher alcohols such as cetyl alcohol.

Moreover, the compounding component which may be added other than this is not limited to this, Moreover, Although all said components can be mix | blended within the range which does not impair the objective and effect of this invention, Preferably it is 0.01-5% weight percentage with respect to a total weight, More preferably 0.01-3% by weight.

The cosmetic of the present invention may take the form of a solution, an emulsion, a viscous mixture, or the like.

Ingredients included in the cosmetic composition of the present invention may include components commonly used in cosmetic compositions in addition to the extract as an active ingredient, for example, conventional auxiliary agents such as stabilizers, solubilizers, vitamins, pigments and flavorings. And carriers.

The cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, and includes, for example, milky lotion, cream, lotion, pack, foundation, lotion, essence, hair cosmetic, and the like.

Specifically, the cosmetic composition of the present invention skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisturizing lotion, nutrition lotion, massage cream, nutrition cream, moisturizing cream, hand cream, foundation, essence, nutrition essence, Formulations of packs, soaps, cleansing foams, cleansing lotions, cleansing creams, body lotions and body cleansers.

When the formulation of the present invention is a paste, cream or gel, animal carriers, vegetable fibers, waxes, paraffins, starches, tracantes, cellulose derivatives, polyethylene glycols, silicones, bentonites, silicas, talc or zinc oxide, etc. may be used as carrier components. Can be.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used, in particular in the case of a spray, additionally chlorofluorohydrocarbon, propane Propellant such as butane or dimethyl ether.

When the formulation of the invention is a solution or emulsion, a solvent, solvating or emulsifying agent is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 Fatty acid esters of, 3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the dosage form of the present invention is a suspension, liquid carrier diluents such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, microcrystalline Cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a surfactant-containing cleansing, the aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid as carrier components Amide ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, linolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.

Hereinafter, the present invention will be described in detail by the following Examples and Experimental Examples.

However, the following Examples and Experimental Examples are merely illustrative of the present invention, and the content of the present invention is not limited by the following Examples and Experimental Examples.

Example 1 Camellia Extract Preparation

1-1. Extract (1)

500 g of completely dried camellia raw material in 10 kg of purified water, extracted by boiling in an extractor equipped with a cooling condenser for 3 hours, filtered through a 400 mesh filter cloth, cooled at room temperature, left to mature at 5-15 ° C. for 7 days, and then aged. Filter by filter paper. This natural mixed extract was concentrated under reduced pressure at 70 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 21 g (dry weight) of the extract (1).

1-2. Extract (2) To Extract (9)

To extract the extract (2) to extract (9) by using the solvent of Table 1 in the same manner as in Example 1-1.

extract menstruum Yield (g) Extract (2) Methanol 23 g Extract (3) ethanol 22 g Extract (4) glycerin 19 g Extract (5) Butylene glycol 18g Extract (6) Propylene glycol 18.5 g Extract (7) Ethanol 24.5 g Extract (8) Hydrous propylene glycol 20 g Extract (9) Water-based butylene glycol 21 g

Example 2 Preparation of Skin Lotion

2-1. Manufacture (1)

2, 3, 4, and 8 were added to 11 in Table 2 in order, followed by stirring and dissolving. Then, 5 was heated to 60 ° C. for dissolution and 10 times were added thereto, followed by stirring. Finally, 1, 6, 7, and 9 were added and stirred sufficiently, and then passed through a microfluidizer before aging. Camellia extract of the raw material 1 used the extract (7) of Example 1-2 as a sample.

2-2. Comparative Manufacturing (1)

A skin lotion was prepared in the same manner as in Example 2-1 except for the first raw material of Table 2.

number Raw material Manufacturing (1) Comparative Manufacturing (1) One  Camellia Extract (Extract (7) of Example 1-2) 5.0 - 2 glycerin 3.0 3.0 3 Butylene Glycol 2.0 2.0 4 Propylene glycol 2.0 2.0 5 Polyoxyethylene (60) Cured Castor Oil 1.00 1.0 6 ethanol 10.0 10.0 7 Triethanolamine 0.1 0.1 8 antiseptic a very small amount a very small amount 9 Pigment a very small amount a very small amount 10 Spices a very small amount a very small amount 11 Purified water Remaining amount Remaining amount

Example 3. Preparation of Nutritional Lotion

3-1.Manufacturing (2)

Homogenized the raw materials 2, 3, 4, 5, and 6 in Table 3 at a constant temperature (hereinafter referred to as nonionic amphiphilic lipids) and mixed raw materials 1, 7, 8, and 14 Homogenized at and passed through the microfluidizer, and then the raw material 9 was slowly added and homogenized at a constant temperature, and then passed through the microfluidizer again. Thereafter, 10, 11, 12 and 13 were added to disperse to stabilize and mature. Camellia extract of the raw material 1 used the extract (7) of Example 1-2 as a sample.

3-2. Comparative Manufacturing (2)

The nutrition lotion was prepared except for the first raw material of Table 3 in the same manufacturing method as in Example 3-1.

number Raw material Manufacturing (2) Comparative Manufacturing (2) One   Camellia Extract (Extract (7) of Example 1-2) 5.0 - 2 Cytostolol 1.70 1.70 3 Polyglyceryl 2-oleate 1.50 1.50 4 Ceramide 0.7 0.7 5 Ceteares-4 1.2 1.2 6 cholesterol 1.5 1.5 7 Dicetylphosphate 0.4 0.4 8 Concentrated glycerin 5.0 5.0 9 Sunflower oil 10.0 10.0 10 Carboxy Vinyl Polymer 0.2 0.2 11 Xanthan Gum 0.3 0.3 12 antiseptic a very small amount a very small amount 13 Spices a very small amount a very small amount 14 Purified water Remaining amount Remaining amount

Example 4 Preparation of Nutritional Cream

4-1. Manufacture (3)

Homogenized the raw materials 2, 3, 4, 5 and 6 in Table 4 (hereinafter referred to as nonionic amphiphilic lipids) and mixed raw materials 1, 7, 8 and 14 Homogenized at and passed through a microfluidizer, and the raw material 9 was gradually added at a constant temperature to homogenize, and then passed through the microfluidizer again. Thereafter, 10, 11, 12 and 13 were added to disperse to stabilize and mature.

4-2. Comparative Manufacturing (3)

Nutritional cream was prepared in the same manner as in Example 4-1 except for the first raw material of Table 4.

number Raw material Manufacture (3) Comparative Manufacturing (3) One   Camellia Extract (Extract (7) of Example 1-2) 5.0 - 2 Cytostolol 4.0 4.0 3 Polyglyceryl 2-oleate 3.0 3.0 4 Ceramide 0.7 0.7 5 Ceteares-4 2.0 2.0 6 cholesterol 3.0 3.0 7 Dicetylphosphate 0.4 0.4 8 Concentrated glycerin 5.0 5.0 9 Sunflower oil 22.0 22.0 10 Carboxy Vinyl Polymer 0.5 0.5 11 Triethanolamine 0.5 0.5 12 antiseptic a very small amount a very small amount 13 Spices a very small amount a very small amount 14 Purified water Remaining amount Remaining amount

Experimental Example 1. Measurement of polyphenol content

In order to determine the polyphenol content of the camellia extract according to the present invention, first, 2, 10, 15 and 20 mg of gallic acid were dissolved in methanol and the camellia extract was dissolved in methanol for standard calibration. 9 ml of purified water was added to each 1 ml of it, and 1 ml folic & ciocalteus phenol reagent was added thereto, followed by stirring for 5 minutes. Then 7% Na₂CO₃ 10 ml was added and 25 ml was filled with purified water, followed by reaction for 60 minutes. Each sample was measured for absorbance at 750 nm, and the standard curves are shown in Table 5 and FIG. 1.

extract sample Abs (750 nm) One Gallic Acid 5mg / 100mL 0.19150 2 Gallic acid 10mg / 100mL 0.44812 3 Gallic Acid 15mg / 100mL 0.70342 4 Gallic Acid 20mg / 100mL 0.94908

Table 6 shows the total polyphenol content of the extracts (1) to (9) of Example 1 based on the standard curve.

extract menstruum Total Polyphenol Content (%) Extract (1) Purified water 4.71 Extract (2) Methanol 5.24 Extract (3) ethanol 5.33 Extract (4) glycerin 4.42 Extract (5) Butylene glycol 4.01 Extract (6) Propylene glycol 4.17 Extract (7) Ethanol 5.76 Extract (8) Hydrous propylene glycol 4.30 Extract (9) Water-based butylene glycol 4.72

Experimental Example 2. Measurement of sebum hypersecretion inhibitory effect

2-1. Inhibition of sebum hypersecretion effect using hemoglobin protein

Most of the skin is made of protein, so it binds to polyphenols and pulls pores to shrink them. As described above, sebum hypersecretion inhibition effect was measured by using a chemical convergence action in which sweat glands and pores were temporarily contracted by a protein-coagulating substance such as tannin. Hemoglobin was used as a protein to replace the skin, and hemoglobin was collected from blood of New Zealand Albino rabbit. After sampling, 2.0 ml of hemoglobin solution prepared by diluting with 50 times purified water and 2.0 ml of sample diluted by concentration were mixed in a centrifuge tube container, shaken and mixed. Was measured. Sebum secretion inhibitory effect was calculated according to the following equation 1, the results are shown in Table 7.

Sebum secretion inhibitory effect (%) = (1-absorbance of test group / absorbance of control group) × 100

extract Final concentration of the sample contained in the reaction solution (㎍ / ㎖)  Sebum secretion inhibitory effect (%) Extract (1)                   50 73.1% Extract (2)                   50 80.9% Extract (3)                   50 82.2% Extract (4)                   50 65.2% Extract (5)                   50 61.8% Extract (6)                   50 63.3% Extract (7)                   50 89.5% Extract (8)                   50 68.4% Extract (9)                   50 73.1%

2-2. Inhibition of sebum hypersecretion effect using albumin protein

Albumin (Sigma) was used as a protein to replace the skin, and albumin solution was prepared at a concentration of 0.3%. 2 ml of various concentrations of the sample and 2 ml of albumin solution were mixed in a centrifuge tube container, and the absorbance was measured at 650 nm after standing at room temperature for 5 minutes. The results are shown in Table 8, and the higher the absorbance value, the better the convergence effect.

  extract Final concentration of the sample in the reaction solution (µg / ml)  Sebum secretion effect (abs.) Extract (1) 10 0.7825 Extract (2) 10 0.9436 Extract (3) 10 0.8691 Extract (4) 10 0.6542 Extract (5) 10 0.6008 Extract (6) 10 0.6206 Extract (7) 10 1.0927 Extract (8) 10 0.7139 Extract (9) 10 0.7828

Experimental Example 3. Oily skin relaxation test

In order to measure the alleviating effect of oily skin when the skin lotion of the manufacture (1) and the comparative manufacture (1) of Example 2 was applied to the skin, a 20-55 year old female layer was prepared on the left part of the forehead to 20 owners of oily skin. The skin lotion of (1) is applied to the right part of the forehead, and the skin lotion of the comparative manufacturing (1) is applied twice a day in the morning and evening, and after 1 week, 2 weeks, 3 weeks and 4 weeks, Sebum secretion of skin was measured using SM 810). The experiment was carried out at 20 ℃, 20% relative humidity and the results are shown in Table 9, the results are shown as the average value of 20 subjects. In the case of oily skin, the measured value is 220 or more, and in the case of normal skin, it is 100 to 220.

Date range Before application 7 14 21 28 Manufacture (1) Application 245 237 229 218 198 Comparative Manufacturing (1) Application 245 240 238 235 230

As shown in Table 9, it was confirmed that the sebum over-secretion effect was excellent by inhibiting sebum oversecretion of the preparation (1) including the extract of Camellia flower, and none of the subjects showed unusual adverse reactions.

As described above, the Camellia extract of the present invention showed an excellent effect in measuring sebum hypersecretion inhibitory effect by pore contraction using hemoglobin protein and albumin protein, and showed an excellent skin oil reduction effect in the skin coating test. It can be used as a convergent cosmetic composition for improving sebum over secretion and oily skin.

Claims (4)

Cosmetic composition containing Camellia japonica L. ethanol extract as an active ingredient, having the effect of pore contraction, sebum oversecretion and skin oil reduction effect. delete The composition of claim 1, wherein the composition is a skin lotion, a skin softener, a skin toner, an astringent, a lotion, a milk lotion, a moisturizer, a nutrition lotion, a massage cream, a nutrition cream, a moisturizer cream, a hand cream, a foundation, an essence, a nutrition essence, a pack Cosmetic composition, characterized in that it has at least one formulation selected from the group consisting of soap, cleansing foam, cleansing lotion, cleansing cream, body lotion and body cleanser. According to claim 1, wherein the extract is a cosmetic composition, characterized in that contained in 0.01 to 5% by weight relative to the total weight of the composition.

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