KR102242879B1 - Dna-코딩된 라이브러리에 태그부착하는 방법 - Google Patents

Dna-코딩된 라이브러리에 태그부착하는 방법 Download PDF

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KR102242879B1
KR102242879B1 KR1020207017041A KR20207017041A KR102242879B1 KR 102242879 B1 KR102242879 B1 KR 102242879B1 KR 1020207017041 A KR1020207017041 A KR 1020207017041A KR 20207017041 A KR20207017041 A KR 20207017041A KR 102242879 B1 KR102242879 B1 KR 102242879B1
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nucleotides
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KR20200074248A (ko
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안쏘니 디. 키페
리차드 더블유. 와그너
알렉산더 리토브치크
매튜 클라크
존 더블유. 쿠오쪼
윙 장
파올로 에이. 센트렐라
크리스토퍼 디. 후프
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엑스-켐, 인크.
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/16—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
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  • Polysaccharides And Polysaccharide Derivatives (AREA)
KR1020207017041A 2011-09-07 2012-09-07 Dna-코딩된 라이브러리에 태그부착하는 방법 Expired - Fee Related KR102242879B1 (ko)

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US201161531820P 2011-09-07 2011-09-07
US61/531,820 2011-09-07
US201161536929P 2011-09-20 2011-09-20
US61/536,929 2011-09-20
PCT/US2012/054228 WO2013036810A1 (en) 2011-09-07 2012-09-07 Methods for tagging dna-encoded libraries

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KR102242879B1 true KR102242879B1 (ko) 2021-04-20

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KR1020147007749A Expired - Fee Related KR102124613B1 (ko) 2011-09-07 2012-09-07 Dna-코딩된 라이브러리에 태그부착하는 방법

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CN (1) CN103998658B (enExample)
AP (1) AP2014007483A0 (enExample)
AU (3) AU2012304387B2 (enExample)
BR (1) BR112014005205A2 (enExample)
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