KR102209432B1 - 치환된 7-아자바이사이클 및 오렉신 수용체 조절제로서의 이의 용도 - Google Patents

치환된 7-아자바이사이클 및 오렉신 수용체 조절제로서의 이의 용도 Download PDF

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KR102209432B1
KR102209432B1 KR1020157028726A KR20157028726A KR102209432B1 KR 102209432 B1 KR102209432 B1 KR 102209432B1 KR 1020157028726 A KR1020157028726 A KR 1020157028726A KR 20157028726 A KR20157028726 A KR 20157028726A KR 102209432 B1 KR102209432 B1 KR 102209432B1
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methyl
alkyl
disorder
alkoxy
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KR20150126695A (ko
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헤더 알. 코트
커트 에이. 드보락
앤 이. 피츠제럴드
테리 피. 레볼드
캐시 프레빌
브록 티. 셔먼
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얀센 파마슈티카 엔.브이.
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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KR1020157028726A 2013-03-13 2014-03-12 치환된 7-아자바이사이클 및 오렉신 수용체 조절제로서의 이의 용도 Active KR102209432B1 (ko)

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Application Number Priority Date Filing Date Title
US201361780428P 2013-03-13 2013-03-13
US61/780,428 2013-03-13
PCT/US2014/024322 WO2014159591A1 (en) 2013-03-13 2014-03-12 Substituted 7-azabicycles and their use as orexin receptor modulators

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