KR102102002B1 - 지혈 조성물 - Google Patents

지혈 조성물 Download PDF

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Publication number
KR102102002B1
KR102102002B1 KR1020147012287A KR20147012287A KR102102002B1 KR 102102002 B1 KR102102002 B1 KR 102102002B1 KR 1020147012287 A KR1020147012287 A KR 1020147012287A KR 20147012287 A KR20147012287 A KR 20147012287A KR 102102002 B1 KR102102002 B1 KR 102102002B1
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South Korea
Prior art keywords
hemostatic composition
hemostatic
syringe
hydrophilic polymer
composition according
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KR1020147012287A
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Korean (ko)
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KR20140074992A (ko
Inventor
한스 크리스티안 헤드리히
요리스 회핑호프
카타르지나 고르나
Original Assignee
백스터 인터내셔널 인코포레이티드
박스터 헬쓰케어 에스에이
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Publication of KR20140074992A publication Critical patent/KR20140074992A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0031Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043Mixtures of macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/008Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polymers & Plastics (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020147012287A 2011-10-11 2012-10-10 지혈 조성물 Active KR102102002B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161545909P 2011-10-11 2011-10-11
US61/545,909 2011-10-11
PCT/EP2012/070061 WO2013053759A2 (en) 2011-10-11 2012-10-10 Hemostatic compositions

Publications (2)

Publication Number Publication Date
KR20140074992A KR20140074992A (ko) 2014-06-18
KR102102002B1 true KR102102002B1 (ko) 2020-04-20

Family

ID=47018202

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147012287A Active KR102102002B1 (ko) 2011-10-11 2012-10-10 지혈 조성물

Country Status (11)

Country Link
US (2) US20130096063A1 (enExample)
EP (2) EP2766059B1 (enExample)
JP (2) JP6195569B2 (enExample)
KR (1) KR102102002B1 (enExample)
CN (1) CN103957949B (enExample)
AU (1) AU2012318257B2 (enExample)
CA (1) CA2851321C (enExample)
ES (1) ES2938568T3 (enExample)
IL (1) IL231961A0 (enExample)
MX (1) MX356185B (enExample)
WO (1) WO2013053759A2 (enExample)

Cited By (1)

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KR20200003397A (ko) * 2017-04-28 2020-01-09 쿡 메디컬 테크놀러지스 엘엘씨 활발한 출혈을 갖는 위장 병변에 대한 이중양식 치료 방법 및 조성물

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US8642831B2 (en) 2008-02-29 2014-02-04 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
JP6195567B2 (ja) * 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 止血組成物
EP2766058B1 (en) 2011-10-11 2022-11-23 Baxter International Inc. Hemostatic compositions
CA2865349C (en) 2012-03-06 2021-07-06 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
EP2825216B1 (en) 2012-06-12 2015-08-19 Ferrosan Medical Devices A/S Dry haemostatic composition
AU2014283170B2 (en) 2013-06-21 2017-11-02 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
RU2678592C1 (ru) * 2013-12-11 2019-01-30 Ферросан Медикал Дивайсиз А/С Сухая композиция, содержащая компонент, улучшающий экструзию
BR112017007466B1 (pt) 2014-10-13 2021-03-02 Ferrosan Medical Devices A/S método para preparar uma composição seca, método para reconstituir a composição seca, pasta, composição seca, recipiente, kit homeostático, e, uso de uma composição seca
BR112017013565B1 (pt) 2014-12-24 2021-12-28 Ferrosan Medical Devices A/S Seringa para retenção e mistura de primeira e segunda substâncias
GB201508024D0 (en) * 2015-05-11 2015-06-24 Haemostatix Ltd Haemostatic compositions
RU2717356C2 (ru) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Шприц для удерживания вакуума в состоянии хранения
CN109200331B (zh) * 2015-12-17 2021-06-25 杭州亚慧生物科技有限公司 一种肺部封合医用凝胶及其制备方法与应用
CN107349462B (zh) * 2016-05-09 2020-07-14 北京纳什国际生物科技有限公司 一种可吸收半流动性交联多肽生物外科止血物
KR20180027126A (ko) 2016-09-06 2018-03-14 (주)한국비엠아이 가교화 히알루론산 유도체 매트릭스가 포함된 지혈 조성물
CN108498879B (zh) 2017-02-28 2021-12-28 苏州安德佳生物科技有限公司 黏膜下注射用组合物和试剂组合及其应用
BR112019018010A2 (pt) * 2017-03-09 2020-04-28 Baxter Healthcare Sa sistema e métodos de deposição de solventes
KR101989054B1 (ko) * 2017-11-28 2019-06-13 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
CN110025821A (zh) 2018-01-12 2019-07-19 北京环球利康科技有限公司 使用生物相容性止血剂和组织封闭剂的组合物处理活动性出血的方法
KR20210008479A (ko) 2018-05-09 2021-01-22 훼로산 메디칼 디바이스 에이/에스 지혈 조성물을 제조하는 방법
US20210236642A1 (en) * 2018-07-26 2021-08-05 Srinivas Reddy Male Haemostatic gel composition and its process of preparation
EP3895890B1 (en) * 2018-12-14 2024-07-03 Bmg Incorporated Two-reactant sheet-form tissue-adhesive-reinforcing material
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BR112022000511A2 (pt) * 2019-07-12 2022-03-03 Gatt Tech B V Folha hemostática flexível biocompatível, embalagem vedada e método de preparação de folhas homeostáticas
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CN116744984A (zh) 2020-12-28 2023-09-12 达沃有限公司 包含蛋白质和多官能化改性的基于聚乙二醇的交联剂的反应性干粉状止血材料
CN115025274B (zh) * 2021-03-04 2023-03-17 海宁侏罗纪生物科技有限公司 一种医用组织粘合胶及其制备方法
CN115252875B (zh) * 2021-04-29 2023-06-16 浙江大学 一种医用组织粘合胶及其制备方法
CN113209357B (zh) * 2021-05-14 2023-02-17 南方科技大学 复合止血粉
CN113599568A (zh) * 2021-08-05 2021-11-05 南方科技大学 合成材料类粉剂及其在止血体系的应用
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