KR102099990B1 - 항-smad7 요법의 반응성을 모니터링하는 방법 - Google Patents

항-smad7 요법의 반응성을 모니터링하는 방법 Download PDF

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KR102099990B1
KR102099990B1 KR1020147009572A KR20147009572A KR102099990B1 KR 102099990 B1 KR102099990 B1 KR 102099990B1 KR 1020147009572 A KR1020147009572 A KR 1020147009572A KR 20147009572 A KR20147009572 A KR 20147009572A KR 102099990 B1 KR102099990 B1 KR 102099990B1
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KR20140059859A (ko
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지오반니 몬텔레오네
프란체스카 비티
살바토레 벨린비아
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노그라 파마 리미티드
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KR1020147009572A 2011-09-15 2012-09-14 항-smad7 요법의 반응성을 모니터링하는 방법 Expired - Fee Related KR102099990B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP11425234 2011-09-15
EP11425234.9 2011-09-15
US201161576556P 2011-12-16 2011-12-16
US61/576,556 2011-12-16
PCT/EP2012/068146 WO2013037970A1 (en) 2011-09-15 2012-09-14 Methods for monitoring responsiveness to anti-smad7 therapy

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KR20140059859A KR20140059859A (ko) 2014-05-16
KR102099990B1 true KR102099990B1 (ko) 2020-04-13

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US (2) US9791442B2 (https=)
EP (2) EP3165929A3 (https=)
JP (1) JP6389122B2 (https=)
KR (1) KR102099990B1 (https=)
CN (1) CN104040349B (https=)
AU (1) AU2012307336B2 (https=)
CA (1) CA2848595A1 (https=)
ES (1) ES2617200T3 (https=)
MX (1) MX350087B (https=)
RU (1) RU2678450C2 (https=)
WO (1) WO2013037970A1 (https=)

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ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
ES2627745T3 (es) 2008-11-13 2017-07-31 Nogra Pharma Limited Composiciones antisentido, y procedimientos de fabricación y uso de las mismas
US10081809B2 (en) 2012-04-18 2018-09-25 University Of Miami Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation
US10006029B2 (en) 2013-03-15 2018-06-26 Nogra Pharma Limited Methods of treating colorectal cancer
RU2674147C2 (ru) * 2013-03-15 2018-12-05 Ногра Фарма Лимитед Способы лечения колоректального рака
US20160139123A1 (en) * 2013-07-12 2016-05-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Shear Wave Imaging Method and Installation for Collecting Information on a Soft Solid
AU2015257589A1 (en) 2014-05-09 2016-11-24 Nogra Pharma Limited Methods for treating inflammatory bowel disease
WO2016059239A1 (en) * 2014-10-17 2016-04-21 Nogra Pharma Limited Methods and compositions for treating a subject with a smad7 antisense oligonucleotide
US20170233736A1 (en) * 2014-10-17 2017-08-17 Nogra Pharma Limited Methods for dosing and monitoring smad7 antisense oligonucleotide treatment using biomarker levels
MA41271A (fr) * 2014-12-26 2017-10-31 Celgene Alpine Invest Company Ii Llc Méthodes d'utilisation d'oligonucléotides antisens ciblant smad7
WO2017019673A2 (en) * 2015-07-27 2017-02-02 Genentech, Inc. Methods for diagnosing and treating inflammatory bowel disease
MX2018003699A (es) * 2015-09-30 2018-08-01 Celgene Alpine Invest Company Ii Llc Moduladores de tlr y metodos de uso.
EP3355896A2 (en) * 2015-09-30 2018-08-08 Nogra Pharma Limited Methods of using smad7 antisense oligonucleotides based on biomarker expression
JP2019505598A (ja) 2016-02-23 2019-02-28 セルジーン アルパイン インベストメント カンパニー Ｉｉ， エルエルシー Ｓｍａｄ７の阻害を用いて、腸線維症を治療する方法
US10517889B2 (en) 2017-09-08 2019-12-31 Ionis Pharmaceuticals, Inc. Modulators of SMAD7 expression
US11619832B2 (en) 2018-03-08 2023-04-04 Coopervision International Limited Identification of contact lens wearers predisposed to contact lens discomfort
CN110082538B (zh) * 2019-04-19 2021-12-03 中山大学附属第六医院 CCR9+IL-17+Treg细胞在制备用于检测NEC的试剂盒中的应用

Citations (3)

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CA2520541A1 (en) * 2003-04-02 2004-10-14 Giovanni Monteleone Antisense oligonucleotides (odn) against smad7 and uses thereof in medical field
WO2008157394A2 (en) * 2007-06-13 2008-12-24 La Jolla Institute For Allergy And Immunology Regulatory t cells and methods of making and using same
US20090275496A1 (en) 2004-05-07 2009-11-05 Peptimmune, Inc. Effective quantitation of complex peptide mixtures in tissue samples and improved therapeutic methods

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US6159697A (en) * 2000-01-19 2000-12-12 Isis Pharmaceuticals, Inc. Antisense modulation of Smad7 expression
RU2185627C2 (ru) * 2000-09-11 2002-07-20 Новосибирская государственная медицинская академия Способ определения чувствительности (восприимчивости) к внутривенной лазеротерапии больных ишемической болезнью сердца
PT1456380E (pt) 2001-11-02 2012-07-23 Giuliani Int Ltd Inibidores smad7 para o tratamento de doenças do snc
CA2617583A1 (en) * 2005-08-02 2007-02-08 Centenary Institute Of Cancer Medicine And Cell Biology Method for identifying regulatory t cells
JP2009529659A (ja) * 2006-03-10 2009-08-20 マウント シナイ ホスピタル 栄養膜細胞の細胞死、分化、浸潤、および／または細胞融合および代謝回転に関連する状態の診断用組成物および治療方法
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RU2674147C2 (ru) 2013-03-15 2018-12-05 Ногра Фарма Лимитед Способы лечения колоректального рака
AU2015257589A1 (en) 2014-05-09 2016-11-24 Nogra Pharma Limited Methods for treating inflammatory bowel disease
WO2016059239A1 (en) 2014-10-17 2016-04-21 Nogra Pharma Limited Methods and compositions for treating a subject with a smad7 antisense oligonucleotide
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EP3355896A2 (en) 2015-09-30 2018-08-08 Nogra Pharma Limited Methods of using smad7 antisense oligonucleotides based on biomarker expression

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CA2520541A1 (en) * 2003-04-02 2004-10-14 Giovanni Monteleone Antisense oligonucleotides (odn) against smad7 and uses thereof in medical field
US20090275496A1 (en) 2004-05-07 2009-11-05 Peptimmune, Inc. Effective quantitation of complex peptide mixtures in tissue samples and improved therapeutic methods
WO2008157394A2 (en) * 2007-06-13 2008-12-24 La Jolla Institute For Allergy And Immunology Regulatory t cells and methods of making and using same

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EP2748611B1 (en) 2016-11-23
KR20140059859A (ko) 2014-05-16
AU2012307336A1 (en) 2014-03-27
RU2678450C2 (ru) 2019-01-29
JP2014531584A (ja) 2014-11-27
MX350087B (es) 2017-08-24
EP2748611A1 (en) 2014-07-02
AU2012307336B2 (en) 2017-08-24
MX2014003295A (es) 2014-05-28
NZ622067A (en) 2016-05-27
EP3165929A3 (en) 2017-06-21
US20150148245A1 (en) 2015-05-28
US20180128829A1 (en) 2018-05-10
NZ719884A (en) 2020-02-28
JP6389122B2 (ja) 2018-09-12
WO2013037970A1 (en) 2013-03-21
CA2848595A1 (en) 2013-03-21
RU2014114838A (ru) 2015-10-20
US9791442B2 (en) 2017-10-17
CN104040349B (zh) 2017-07-04
EP3165929A2 (en) 2017-05-10
HK1199095A1 (en) 2015-06-19
CN104040349A (zh) 2014-09-10
ES2617200T3 (es) 2017-06-15

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