KR102076337B9 - 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용 - Google Patents
히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용Info
- Publication number
- KR102076337B9 KR102076337B9 KR1020190062079A KR20190062079A KR102076337B9 KR 102076337 B9 KR102076337 B9 KR 102076337B9 KR 1020190062079 A KR1020190062079 A KR 1020190062079A KR 20190062079 A KR20190062079 A KR 20190062079A KR 102076337 B9 KR102076337 B9 KR 102076337B9
- Authority
- KR
- South Korea
- Prior art keywords
- hyaluronic acid
- dna
- injection
- cross
- acid derivative
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 2
- 229920002674 hyaluronan Polymers 0.000 title 1
- 229960003160 hyaluronic acid Drugs 0.000 title 1
- 238000002347 injection Methods 0.000 title 1
- 239000007924 injection Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020150164932 | 2015-11-24 | ||
KR20150164932 | 2015-11-24 | ||
KR1020160157725A KR20170060599A (ko) | 2015-11-24 | 2016-11-24 | 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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KR1020160157725A Division KR20170060599A (ko) | 2015-11-24 | 2016-11-24 | 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용 |
Publications (3)
Publication Number | Publication Date |
---|---|
KR20190060752A KR20190060752A (ko) | 2019-06-03 |
KR102076337B1 KR102076337B1 (ko) | 2020-02-11 |
KR102076337B9 true KR102076337B9 (ko) | 2023-12-29 |
Family
ID=58764176
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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KR1020160157725A KR20170060599A (ko) | 2015-11-24 | 2016-11-24 | 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용 |
KR1020190062079A KR102076337B1 (ko) | 2015-11-24 | 2019-05-27 | 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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KR1020160157725A KR20170060599A (ko) | 2015-11-24 | 2016-11-24 | 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용 |
Country Status (8)
Country | Link |
---|---|
US (1) | US10456347B2 (ko) |
EP (1) | EP3381438B1 (ko) |
JP (1) | JP6660469B2 (ko) |
KR (2) | KR20170060599A (ko) |
CN (1) | CN108289825B (ko) |
ES (1) | ES2953928T3 (ko) |
RU (1) | RU2697671C1 (ko) |
WO (1) | WO2017091017A1 (ko) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111918639A (zh) * | 2017-12-29 | 2020-11-10 | 马特克斯拉比有限公司 | 使用特定交联剂制备具有透明质酸基的填充物的方法 |
KR102010369B1 (ko) * | 2018-02-13 | 2019-08-13 | 강은희 | 셀룰라이트 개선을 위한 주사용 조성물 |
KR102410132B1 (ko) * | 2018-02-26 | 2022-06-17 | 주식회사 뉴온 | 조직 수복용 히알루론산 피부 충진제 조성물 |
KR102144615B1 (ko) * | 2018-08-09 | 2020-08-13 | 장건주 | 폴리데옥시리보뉴클레오타이드를 포함하는 마이셀, 약물 전달체 및 이의 제조방법 |
IT201900001081A1 (it) * | 2019-01-24 | 2020-07-24 | Mastelli S R L | Composizione per il trattamento delle parodontiti e la rigenerazione della papilla interdentale |
KR20210044168A (ko) * | 2019-10-14 | 2021-04-22 | 손진경 | 필러 조성물 |
WO2021125373A1 (ko) * | 2019-12-17 | 2021-06-24 | 주식회사 엘앤씨바이오 | 지방조직 유래 세포외기질을 포함하는 의료용 조성물 및 그 제조방법 |
EP3882279A1 (en) * | 2020-03-16 | 2021-09-22 | Perpetuum CropScience BVBA | Genipin-crosslinked pdrn-sacran biopolymer scaffolds |
KR102181033B1 (ko) * | 2020-03-31 | 2020-11-20 | 주식회사 휴메딕스 | 생분해성 고분자 미립자, 이를 포함하는 고분자 필러 및 이의 제조방법 |
CN111214694B (zh) * | 2020-03-31 | 2022-04-22 | 山东大鱼生物技术有限公司 | 一种具有止血和加速伤口愈合功能的敷料及其制备方法 |
KR102358306B1 (ko) * | 2020-10-08 | 2022-02-07 | 김예주 | 목주름 개선을 위한 주사용 조성물 |
KR102500398B1 (ko) * | 2020-12-10 | 2023-02-16 | (주)인벤티지랩 | 조직 수복용 주사제 조성물 및 이의 제조 방법 |
RU2755346C1 (ru) * | 2020-12-11 | 2021-09-15 | Денис Григорьевич Кайгородов | Композиция, содержащая фактор модернизации эпигенома, обладающая репаративным, онкопротекторным и противовоспалительным действием |
CN115192771B (zh) * | 2021-04-14 | 2024-02-27 | 华熙生物科技股份有限公司 | 一种含透明质酸-多聚脱氧核糖核苷酸共聚物的凝胶及其用途 |
CN115197341B (zh) * | 2021-04-14 | 2024-02-27 | 华熙生物科技股份有限公司 | 一种透明质酸-多聚脱氧核糖核苷酸共聚物及其制备方法和用途 |
CN115192500A (zh) * | 2021-09-28 | 2022-10-18 | 杭州科腾生物制品有限公司 | 具有皮肤抗敏修复和皮肤再生功能的组合物及其制备方法 |
CN114642606B (zh) * | 2022-04-18 | 2024-02-13 | 山东禾三千医疗科技有限公司 | 一种具有皮肤屏障修复功能的组合物及其制备方法和应用 |
CN115105645B (zh) * | 2022-06-28 | 2023-05-26 | 北京化工大学 | 一种复合微球、伤口修复敷料的制备方法 |
CN116531402B (zh) * | 2023-06-27 | 2024-03-22 | 恒昱生物制药(山东)有限公司 | 一种抗炎抗病毒的配方、滴眼液及其应用 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2704431B1 (fr) | 1993-04-30 | 1995-07-21 | Sebbin Laboratoires | Utilisation d'hydrogels à base d'acide hyaluronique et/ou de polydésoxyribonucléotides comme matériaux de remplissage de prothèses et prothèses en résultant. |
DE19815090A1 (de) | 1998-04-06 | 1999-10-14 | Henkel Kgaa | Kosmetische Mittel |
FR2811996B1 (fr) | 2000-07-19 | 2003-08-08 | Corneal Ind | Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations |
JP2005176830A (ja) | 2003-11-28 | 2005-07-07 | Nof Corp | 核酸導入用キャリアー |
FR2865737B1 (fr) | 2004-02-03 | 2006-03-31 | Anteis Sa | Gel reticule biocompatible |
JP4210231B2 (ja) * | 2004-03-25 | 2009-01-14 | 株式会社資生堂 | 皮膚のシワを改善する美容方法及びシワ改善具 |
FR2909560B1 (fr) | 2006-12-06 | 2012-12-28 | Fabre Pierre Dermo Cosmetique | Gel d'acide hyaluronique pour injection intradermique |
JP5574083B2 (ja) | 2008-08-01 | 2014-08-20 | アンタイス エス.エイ. | 高い残留性及び容量を与える高い能力を有する注入可能なヒドロゲル |
US8357795B2 (en) * | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
GB0816496D0 (en) | 2008-09-10 | 2008-10-15 | Zhao Xiaobin | Hyaluronic acid cryogel |
US8679470B2 (en) | 2008-11-28 | 2014-03-25 | Luromed Llc | Composition using cross-linked hyaluronic acid for topical cosmetic and therapeutic applications |
FR2948286B1 (fr) * | 2009-07-27 | 2011-08-26 | Jean-Noel Thorel | Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes |
IT1401218B1 (it) * | 2010-07-14 | 2013-07-12 | Mastelli S R L | Composizione ad attivita' bio-rigenerativa, riparativa ed eutrofizzante. |
WO2012013884A1 (fr) * | 2010-07-29 | 2012-02-02 | Laboratoires Fournier Sa | Composes pour le traitement/la prevention des maladies inflammatoires oculaires |
KR101476381B1 (ko) | 2010-08-09 | 2014-12-24 | 정래준 | 어류 정액 또는 알로부터 분리된 dna 중합체 단편복합체를 포함하는 세포활성 강화용 조성물, 및 얼굴 또는 피부 충진제 |
JP2014520844A (ja) * | 2011-07-13 | 2014-08-25 | チャバイオ&ディオステック カンパニー,リミテッド | コラーゲン、ヒアルロン酸誘導体及び哺乳類の臍帯由来幹細胞を含む軟骨細胞治療剤 |
ES2899992T3 (es) | 2011-08-10 | 2022-03-15 | Glycores 2000 Srl | Acido hialurónico reticulado de bajo peso molecular resistente a la degradación |
KR101445265B1 (ko) * | 2012-09-18 | 2014-09-30 | 포항공과대학교 산학협력단 | 히알루론산-핵산 접합체 및 이를 포함하는 핵산 전달용 조성물 |
KR101773989B1 (ko) | 2012-10-08 | 2017-09-12 | 앙테이스 에스.아. | 가교된 히알루론산 및 수산화 인회석 기재의 에스테틱 용도로 주입가능한 멸균 수계 제형 |
KR102049568B1 (ko) | 2013-04-01 | 2019-11-27 | 삼성전자주식회사 | 히알루론산을 포함하는 핵산전달용 조성물 |
WO2014198406A1 (en) | 2013-06-11 | 2014-12-18 | Anteis S.A. | Method for crosslinking hyaluronic acid; method for preparing an injectable hydrogel; hydrogel obtained; use of the obtained hydrogel |
KR102275105B1 (ko) | 2013-09-09 | 2021-07-09 | 주식회사 휴메딕스 | 고밀도 망상구조로 가교된 히알루론산 및 그의 제조방법 |
KR101582380B1 (ko) | 2013-09-11 | 2016-01-05 | 주식회사 제네웰 | 손상 조직에 대한 세포 전달 및 조직 재생용 생체재료와 제조방법 |
ES2668981T3 (es) | 2013-09-27 | 2018-05-23 | Anteis S.A. | Método para obtener un hidrogel inyectable basado en ácido hialurónico que contiene lidocaína añadida en forma de polvo, y un agente alcalino, esterilizado con calor |
TR201909270T4 (tr) * | 2014-02-20 | 2019-07-22 | Mastelli S R L | Dermokozmetik dolgu maddesi ve bunun estetik amaçlara yönelik kullanımları. |
KR101710639B1 (ko) | 2016-06-07 | 2017-03-08 | 주식회사 파마리서치프로덕트 | 핵산, 키토산 및 히알루론산을 포함하는 조직 증강용 충전 조성물 및 이의 제조방법 |
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KR20170060599A (ko) | 2017-06-01 |
RU2697671C1 (ru) | 2019-08-16 |
US20180325798A1 (en) | 2018-11-15 |
EP3381438B1 (en) | 2023-06-07 |
EP3381438A4 (en) | 2019-08-14 |
JP6660469B2 (ja) | 2020-03-11 |
CN108289825B (zh) | 2022-03-25 |
EP3381438A1 (en) | 2018-10-03 |
ES2953928T3 (es) | 2023-11-17 |
JP2019500332A (ja) | 2019-01-10 |
WO2017091017A1 (ko) | 2017-06-01 |
KR102076337B1 (ko) | 2020-02-11 |
CN108289825A (zh) | 2018-07-17 |
KR20190060752A (ko) | 2019-06-03 |
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