KR102067075B1 - 이온 교환 막 크로마토그래피 - Google Patents

이온 교환 막 크로마토그래피 Download PDF

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KR102067075B1
KR102067075B1 KR1020147019968A KR20147019968A KR102067075B1 KR 102067075 B1 KR102067075 B1 KR 102067075B1 KR 1020147019968 A KR1020147019968 A KR 1020147019968A KR 20147019968 A KR20147019968 A KR 20147019968A KR 102067075 B1 KR102067075 B1 KR 102067075B1
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antibody
membrane
polypeptide
antibodies
ion exchange
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KR20140114834A (ko
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제롬 조셉 제이알. 빌
아리크 마이클 브라운
크리스토퍼 존 다우드
브룩 엘렌 테이어
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제넨테크, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
KR1020147019968A 2011-12-22 2012-12-18 이온 교환 막 크로마토그래피 Active KR102067075B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579285P 2011-12-22 2011-12-22
US61/579,285 2011-12-22
PCT/US2012/070373 WO2013096322A1 (en) 2011-12-22 2012-12-18 Ion exchange membrane chromatography

Related Child Applications (1)

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KR1020207000846A Division KR20200008022A (ko) 2011-12-22 2012-12-18 이온 교환 막 크로마토그래피

Publications (2)

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KR20140114834A KR20140114834A (ko) 2014-09-29
KR102067075B1 true KR102067075B1 (ko) 2020-01-17

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ID=47430154

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020147019968A Active KR102067075B1 (ko) 2011-12-22 2012-12-18 이온 교환 막 크로마토그래피
KR1020207000846A Ceased KR20200008022A (ko) 2011-12-22 2012-12-18 이온 교환 막 크로마토그래피
KR1020217005616A Ceased KR20210025692A (ko) 2011-12-22 2012-12-18 이온 교환 막 크로마토그래피

Family Applications After (2)

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KR1020207000846A Ceased KR20200008022A (ko) 2011-12-22 2012-12-18 이온 교환 막 크로마토그래피
KR1020217005616A Ceased KR20210025692A (ko) 2011-12-22 2012-12-18 이온 교환 막 크로마토그래피

Country Status (21)

Country Link
US (3) US10364268B2 (https=)
EP (2) EP2794635B8 (https=)
JP (5) JP6605202B2 (https=)
KR (3) KR102067075B1 (https=)
CN (2) CN108892706A (https=)
AR (1) AR089362A1 (https=)
AU (3) AU2012355356B2 (https=)
BR (1) BR112014015101A8 (https=)
CA (1) CA2859376C (https=)
ES (1) ES2697676T3 (https=)
HR (1) HRP20181846T1 (https=)
IL (2) IL267585B (https=)
MX (2) MX360453B (https=)
MY (1) MY172426A (https=)
PL (1) PL2794635T3 (https=)
RU (1) RU2648999C2 (https=)
SG (1) SG11201403437TA (https=)
SI (1) SI2794635T1 (https=)
TR (1) TR201815709T4 (https=)
WO (1) WO2013096322A1 (https=)
ZA (2) ZA201404593B (https=)

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CN104693303B (zh) * 2015-02-28 2018-03-13 苏州金盟生物技术有限公司 一种蛋白制品中的核酸去除方法
LT4209499T (lt) 2015-08-13 2024-11-25 Amgen Inc. Antigeną surišančių baltymų įkrautas giluminis filtravimas
GB201711481D0 (en) 2017-07-17 2017-08-30 Ucb Biopharma Sprl Protein purification
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
US10792618B2 (en) 2018-06-19 2020-10-06 Sartorius Stedim Biotech Gmbh Particle separation and/or purification of a fluid
KR102140531B1 (ko) * 2018-08-07 2020-08-04 (주)휴온스 Gly-Tβ4의 제조방법
KR102893280B1 (ko) * 2018-08-14 2025-12-01 브리스톨-마이어스 스큅 컴퍼니 개선된 단백질 회수
GB201815405D0 (en) * 2018-09-21 2018-11-07 Fujifilm Mfg Europe Bv Membranes suitable for detecting, filtering and/or purifying biomolecules
WO2020128797A1 (en) * 2018-12-21 2020-06-25 3M Innovative Properties Company Method for testing a chromatography device used for ion exchange
AR119264A1 (es) * 2019-06-05 2021-12-09 Genentech Inc Método para reutilización de cromatografía
KR20220143676A (ko) * 2020-01-24 2022-10-25 엘커메스 파마 아일랜드 리미티드 정제 방법
US11416468B2 (en) * 2020-07-21 2022-08-16 International Business Machines Corporation Active-active system index management
CN116425826A (zh) * 2021-12-30 2023-07-14 广州百济神州生物制药有限公司 一种快速纯化质量样品的方法
CN116371011B (zh) * 2023-05-26 2023-08-18 湖南杰萃生物技术有限公司 一种从桑叶中提取黄酮和生物碱的方法
CN117866038B (zh) * 2024-03-11 2024-05-28 北京百力格生物科技有限公司 纯化含有宿主核酸的带亲和标签的酸性蛋白的方法

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AU2020201070A1 (en) 2020-03-05
EP3492486A1 (en) 2019-06-05
JP2021169454A (ja) 2021-10-28
CN108892706A (zh) 2018-11-27
JP2020040952A (ja) 2020-03-19
JP7359807B2 (ja) 2023-10-11
CN104125963B (zh) 2018-08-17
HRP20181846T1 (hr) 2018-12-28
US10364268B2 (en) 2019-07-30
KR20200008022A (ko) 2020-01-22
ZA201404593B (en) 2022-12-21
IL233158B (en) 2019-07-31
AU2012355356B2 (en) 2017-10-12
JP6605202B2 (ja) 2019-11-13
US20240247027A1 (en) 2024-07-25
HK1203526A1 (en) 2015-10-30
ZA201903994B (en) 2023-12-20
PL2794635T3 (pl) 2019-02-28
US20140348845A1 (en) 2014-11-27
MX360453B (es) 2018-11-01
RU2014130017A (ru) 2016-02-10
US20200102346A1 (en) 2020-04-02
WO2013096322A1 (en) 2013-06-27
JP7402011B2 (ja) 2023-12-20
MY172426A (en) 2019-11-25
ES2697676T3 (es) 2019-01-25
IL267585A (en) 2019-08-29
AU2018200194B2 (en) 2019-11-14
WO2013096322A8 (en) 2014-02-27
RU2648999C2 (ru) 2018-03-29
AR089362A1 (es) 2014-08-20
EP2794635A1 (en) 2014-10-29
IL233158A0 (en) 2014-07-31
JP2015503524A (ja) 2015-02-02
CN104125963A (zh) 2014-10-29
AU2012355356A1 (en) 2014-07-10
BR112014015101A8 (pt) 2021-06-08
TR201815709T4 (tr) 2018-11-21
JP2018109024A (ja) 2018-07-12
US11945837B2 (en) 2024-04-02
CA2859376C (en) 2022-04-19
BR112014015101A2 (pt) 2017-06-13
AU2018200194A1 (en) 2018-02-01
CA2859376A1 (en) 2013-06-27
JP2022101557A (ja) 2022-07-06
NZ626949A (en) 2016-11-25
EP2794635B8 (en) 2018-11-14
MX2014007622A (es) 2014-09-22
KR20140114834A (ko) 2014-09-29
KR20210025692A (ko) 2021-03-09
SI2794635T1 (sl) 2018-12-31
SG11201403437TA (en) 2014-07-30
MX2018013356A (es) 2020-09-14
WO2013096322A9 (en) 2013-08-22
EP2794635B1 (en) 2018-09-12
IL267585B (en) 2022-09-01

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