KR102054160B1 - Cosmetic composition for preventing scalp aging and hair loss - Google Patents

Abstract

The present invention relates to a cosmetic composition having an effect of preventing and alleviating scalp aging and preventing hair loss, and more particularly, to a hair loss preventing agent composition containing menthol, salicylic acid, adenosine, and dexpanthenol. By using the hair loss preventing agent containing menthol, salicylic acid, adenosine and dexpanthenol of the present invention, it is possible to prevent, alleviate and prevent scalp aging, thereby improving the hair loss prevention effect.

Description

Cosmetic composition which prevents and relieves scalp aging and prevents hair loss {COSMETIC COMPOSITION FOR PREVENTING SCALP AGING AND HAIR LOSS}

The present invention relates to a cosmetic composition having the effect of preventing and alleviating scalp aging and preventing hair loss.

With the development of modern medicine, medical technology has been developed that improves and treats many of the diseases that have a fatal effect on life. However, with the development of society, aesthetic factors become relatively important, and hair loss has recently emerged as a social problem.

Human hair has about 100,000 to 150,000 different cycles and grows or drops out during the growth, degenerative, and rest periods. Generally, alopecia refers to a shorter hair growth period and more hair during the degenerative or resting phase. This is an increase in the number of abnormal hair loss.

Known causes of hair loss may be influenced by several factors, including age, season, race, physiological factors, and disease, but include: 1) excessive male hormone action, 2) excessive sebum secretion, 3) poor blood circulation, 4) the deterioration of scalp function due to peroxides and bacteria, 5) genetic factors, 6) aging, and 7) stress.

In the early stages of hair loss, scalp diseases such as dandruff and seborrheic dermatitis are widely known as typical initial symptoms. Especially, scalp inflammation is caused by abnormal skin reactions to various contaminants, bacteria, endocrine problems, and autonomy. Physical factors such as excessive sebum production due to circulatory problems such as nervous system disorders, blood circulation disorders, malnutrition of hair roots, allergies, bacterial infections, genetic factors such as hormonal effects, and various pollution and processed foods Environmental factors such as shampoo, soap, mousse, hair gel, hair spray, perm, dyeing, hair dryer, detergent use, and mental and social factors of modern people who are frequently stressed are known to appear in combination.

These factors are expected to increase the demand of hair loss patients to prevent hair loss and maintain wool as the hair loss patients rapidly increase.

However, as an active ingredient, there are various hair loss products including ingredients aimed at promoting blood circulation, strengthening hair root function, moisturizing scalp, preventing dandruff, antioxidant, hair growth period, and inhibiting male hormone action. In terms of effectiveness, no clear effect has yet been demonstrated, and side effects are raised.

Accordingly, a situation in which hair loss preventing agents using natural extracts having fewer side effects is being developed.

As a prior art regarding a hair loss preventing agent using such a natural extract, Korean Patent No. 10-1780692 (Patent Document 1) can be exemplified. The patent relates to a composition for preventing hair loss or promoting hair growth using a mixed extract of green tea and Amra or a mixed extract of eochocho, green tea and hibiscus as an active ingredient, and discloses a natural complex extract, Active ingredients are very different.

KR 10-1780692 B1 (September 25, 2017)

The present invention aims to solve the above problems, and finds that prevention, alleviation and improvement of hair loss can be prevented, alleviated and improved by preventing, alleviating and preventing scalp aging, and a hair loss preventing composition having efficacy of preventing, alleviating and preventing scalp aging. And to provide a hair loss preventing agent using the same.

The present invention has been made to solve the above problems of the prior art,

An anti-hair loss composition containing menthol, salicylic acid, adenosine, and dexpanthenol is provided.

In addition, in the present invention, the composition provides a hair loss preventing composition having an effect of aging, preventing and preventing scalp aging.

Also in the present invention, the composition is scalpized containing 0.05-2% by weight of menthol, 0.05-2% by weight of salicylic acid, 0.01-0.5% by weight of adenosine, and 0.05-15% by weight of dexpanthenol, relative to the total weight It provides a hair loss preventing agent composition for relief.

In addition, in the present invention, the composition is retinol, tocopherol, ascorbic acid, collagen, island oakpi fruit extract, purple heaven extract, iris root extract, thistle flower / leaf / stem extract, propolis extract, gusset extract, jeju jeju extract and It provides a hair loss preventing composition for scalp mitigation further comprising at least one additional component selected from the hose pat.

In the present invention, the additional component, the total content provides a hair loss preventing composition of 0.01-20% by weight based on the total weight of the composition.

In addition, the present invention provides a cosmetic for preventing hair loss, comprising the composition of the present invention, prepared in a formulation selected from cream, lotion, essence, serum, toner, tonic, and mist.

By using the hair loss preventing agent containing menthol, salicylic acid, adenosine and dexpanthenol of the present invention, it is possible to prevent, alleviate and prevent scalp aging, thereby improving the hair loss prevention effect.

1 is a result showing the effect of preventing hair loss, hair thickness, hair density before and after using the hair loss preventing agent of the present invention.

Hereinafter, embodiments of the present invention will be described in detail. However, this is presented as an example, by which the present invention is not limited and the present invention is defined only by the scope of the claims to be described later.

In describing the present invention, when it is determined that the detailed description of the related well-known configuration or function may obscure the gist of the present invention, the detailed description thereof will be omitted.

In describing the components of the present invention, terms such as first, second, A, B, (a), and (b) can be used. These terms are only for distinguishing the components from other components, and the nature, order or order of the components are not limited by the terms.

The terms 'about', 'substantially', 'degree' and the like used in the description of the present invention are intended to be in or close to the numerical values when manufacturing and material tolerances inherent in the meanings mentioned are given. It is used to prevent an unscrupulous infringer from using the disclosure in which the exact or absolute figures are mentioned to aid the understanding of the present invention.

The hair loss preventing agent composition which can prevent, alleviate and prevent scalp aging according to an embodiment of the present invention may include menthol, salicylic acid, adenosine and dexpanthenol.

The menthol is used for stomach pain, toothache, and the like, which is good for pain and inflammation, and has an effect of cooling the scalp, thereby adding a refreshing feeling of the scalp.

The menthol preferably contains 0.05-2% by weight relative to the total weight, more preferably 0.1-1.0% by weight.

When the menthol content is less than 0.05% by weight, the efficacy and effects are insignificant, and when the menthol content is higher than 2% by weight, there may be a problem of excessive cooling or irritation and unstable formulation.

The salicylic acid is a widely used ingredient for skin-related diseases such as acne, dandruff, keratin and corn, and softens softening of the anti-inflammatory or scalp keratin to remove the dead skin cells and wastes remaining inside the pores. It can help you.

The salicylic acid preferably contains 0.05-2% by weight relative to the total weight, and if it exceeds 0.1-1% by weight, skin irritation may occur.

The adenosine is a component that promotes the synthesis of collagen, improves wrinkles and improves skin elasticity.

Adenosine preferably contains 0.01-0.5% by weight relative to the total weight, more preferably 0.02-0.2% by weight.

When the adenosine content is less than 0.01% by weight, the efficacy and effect is insignificant, and the elasticity improvement effect of the scalp is insignificant, and when it exceeds 0.5% by weight, the stability is lowered in the product and the effect is not enhanced. May appear.

Dexpanthenol is provitamin B5, which is converted to vitamins after absorption into the body, which can prevent inflammation and itching, soften hair, and enhance hair strength.

Dexpanthenol preferably contains 0.05-15% by weight, more preferably 0.1-10% by weight relative to the total weight.

When the content of dexpanthenol is less than 0.05% by weight, the efficacy and effects are insignificant, and when the content of dexpanthenol exceeds 15% by weight, the effect is not enhanced and the usability and stability may be poor.

In order to further improve the efficacy of the hair loss preventing composition that can prevent, alleviate and prevent scalp aging, retinol, tocopherol, ascorbic acid, collagen, sesame galli fruit extract, purple natural extract, iris root extract, thistle flower / leaf / stem It may further comprise one or more of extracts, propolis extracts, portulaca extracts, jeju jeoldae extracts and hose pat.

The retinol is a type of vitamin A, which plays an important role in maintaining the epidermal cells of the skin, and is particularly effective for improving wrinkles and preventing skin aging.

The tocopherol is a type of vitamin E, a fat-soluble vitamin, and has an antioxidant effect, which inhibits oxidation of unsaturated fatty acids constituting cell membranes, thereby preventing cell membrane damage and further damage to tissues, inhibiting aging and maintaining skin elasticity. High potency ingredient.

The ascorbic acid is one of the water-soluble vitamins and is an antioxidant of vitamin C, which protects the body from free radicals and prevents oxidation of cells, and also plays an important role in protecting the skin from ultraviolet rays.

The collagen is a component that can significantly increase the moisturizing power when blended in cosmetics, in particular the texture is improved to improve the feeling of use.

The island ogopi tree is an elmaceae plant whose recycled land is Jeju Island.

Ogalpi tree has been used for medicinal purposes since the Goryeo Dynasty, and it is known that the bark of roots, stems and branches is called Ogapi, its leaves are called Ogap, and it increases the resistance of living organisms to biological adversity. Auberge fruit extract has very good antioxidant and anti-inflammatory effects.

The extract of CHO is not cytotoxic and has an excellent anti-inflammatory effect by inhibiting various cytokines and NO mediated inflammatory reactions, and may be effective in preventing skin aging and enhancing skin barrier due to its high antioxidant effect. .

The irises are distributed in Korea, Japan, and China, and are perennial herbaceous plants growing in ponds or ditches. In oriental medicine, the functions of organs such as eyes, nose, mouth, ears, urethra, and anus in our body It also has high detoxification, antibacterial and anti-inflammatory effects that release toxins in the body. In particular, the iris root has an excellent effect on improving the weak constitution, the essential oil of the iris is known to relieve blood circulation, pain, fatigue, etc., and particularly has an excellent antioxidant effect.

The thistle is a perennial plant of Asteraceae, flower / leaf / stem extract is applied to the skin thistle starch extract to enhance the ARE protein activity related to the antioxidant protein Nrf-2, always exposed to the outside of the stressed skin Maintains homeostasis and prevents skin aging caused by free radicals.

The propolis is excellent in organic matter and minerals, especially minerals, vitamins, amino acids, fats, organic acids, flavonoids, etc. play an important role in cell metabolism, terpenes, etc., and anti-cancer action, and flavonoids help to promote health give. This propolis is effective in anti-inflammatory, antioxidant and immune boosting.

Machihyeon is a leaf-shaped horse's teeth, the meaning of a wild axil eating, in other words also called purslane. This purslane is known to have a lot of omega-3 fatty acids, a type of unsaturated fatty acid. This extract is excellent in antioxidant and anti-inflammatory effects.

The stalk is a monocotyledonous plant of the rice family distributed in Korea and Japan, in particular, the Jeju stalk distributed in Jeju is resistant to cold and snow and has a lifespan of 60-120 years, and is effective in preventing cancer, antioxidant and obesity. It is known, especially the moisturizing effect is very high.

The hospat is a component excellent in antioxidant and anti-inflammatory effects, it is possible to maintain skin homeostasis and prevent skin aging by enhancing the ARE activity associated with the antioxidant protein Nrf-2.

In addition, the extracts of the island oakpi fruit extract, purple natural extract, iris iris extract, thistle flower / leaf / stem extract, propolis extract, guchihyun extract, scavenger extract and hospat are not local restrictions, but in UNESCO Jeju Island, a clean area designated as a biosphere reserve, is preferably a native area.

The total content of the retinol, tocopherol, ascorbic acid, collagen, island ogalpi fruit extract, purple natural extract, iris root extract, thistle flower / leaf / stem extract, propolis extract, gut extract, Jeju jeju extract and hospat the total composition 0.01-20% by weight relative to the weight may be further included, and preferably 0.1-10% by weight is further included.

Taken together, the hair loss preventing composition according to the present invention is not only excellent in efficacy as a hair loss preventing agent, but can also alleviate and improve hair loss that can be accelerated by preventing, alleviating, and preventing aging of the scalp. Will be self explanatory.

In addition, the hair loss preventing agent composition is prepared in the form of creams, lotions, essences, serums, toners, tonics, mists, etc., and applied to the scalp to keep the scalp healthy, in particular, as a hair loss preventing agent that can prevent, alleviate, and prevent aging of the scalp. Can be used.

Hereinafter, the present invention will be described further through the production and test examples. These examples are intended to illustrate the present invention more specifically, but the scope of the present invention is not limited to these examples.

Production Example

Preparation of Examples 1-7 and Comparative Examples 1-2

According to the composition ratio of Preparation Example 1-7 and Comparative Example 1-2 shown in Table 1, after melting the purified water, glycerin, butylene glycol, 1,2 hexanediol, disodium ethane and warmed to about 70 ℃ Solution 1 was prepared to prepare caprylic / capric triglyceride, triethylhexanoin, cetearyl alcohol, cyclopentasiloxane, palmitic acid, stearic acid, cyclohexasiloxane, and a surfactant poly Soluate 60, PHYG-100 stearate, glyceryl stearate, and sorbitan stearate were added and heated to about 70 ° C to dissolve to prepare Solution 2. The prepared solution 2 was mixed, emulsified and cooled by adding the prepared solution 2, and then the ingredients of 3 were added and mixed uniformly to prepare a hair loss preventing composition having an effect of alleviating scalp aging.

Test Example  One

The hair loss preventing agent having the scalp aging prevention, alleviation and prevention effect prepared according to Table 1 was used for morning and evening after washing hair for 18 adult men and women, and after 6 months, the average amount of hair loss after washing the hair The increase / decrease rate, hair thickness and hair density were measured according to a predetermined evaluation method, and the average value was calculated and evaluated, and the results are shown in Table 3 below.

1) Determination of the rate of change of hair loss after hair washing

The hair loss preventing agent having the effect of preventing, alleviating, and preventing the scalp of the present invention, for each of 18 adult men and women with hair loss, each of two persons, the number of hairs dropped before and after use and after 6 months of use after washing the hair, It was measured, and evaluated according to the evaluation criteria as shown in Table 2 below, the results were as shown in Tables 3 to 5.

As can be seen in Table 3, it can be seen that Examples 1 to 7 using the hair loss preventing agent that can prevent, relax and prevent aging of the scalp of the present invention significantly reduced the number of hair loss than Comparative Examples 1 and 2. .

2) Hair diameter measurement (Hair diameter, nm)

The hair thickness was measured by performing a phototrichogram, and the measuring device is a device for analyzing the characteristics of the hair based on a photograph taken using a high resolution digital macro camera, Folliscope 4.0 (Lead M, Korea) The test site was measured using.

The measurement method was for the scalp of a certain area (1 cm 2), and the average value of five hair thicknesses among the hairs in the area was used as the evaluation data, and the results are shown in Table 4 and FIG. 1.

As can be seen in Table 4, it can be seen that Examples 1 to 7 using the hair loss prevention agent that can prevent, relax and prevent aging of the scalp of the present invention significantly increased the thickness of the hair than Comparative Examples 1 and 2.

3) Hair density measurement (Hair diameter, nm)

The hair density was measured by performing a phototrichogram, and the measuring device is a device for analyzing the characteristics of the hair based on a photograph taken using a high resolution digital macro camera, Folliscope 4.0 (Lead M, Korea) The test site was measured using.

The measurement method was to cover the scalp of a certain area (1㎠), and the number of hairs in the area was used as an evaluation data, and the results are shown in Table 5.

As can be seen in Table 5, it can be seen that Examples 1 to 7 using the hair loss preventing agent that can prevent, relax and prevent aging of the scalp of the present invention significantly increased the hair density than Comparative Examples 1 and 2. In the comparative example, the hair density was not changed before and after 6 months of use, whereas Examples 1 to 7 increased by 101-122% compared to the initial stage.

Test Example  2

The hair loss prevention agent having the scalp aging prevention, alleviation and prevention effect prepared according to Table 1 was used for morning and evening after washing hair for 9 adult men and women, and after 6 months, hairline elasticity measurement and scalp Moisture measurement was measured according to a predetermined evaluation method, the results were as shown in Tables 6 and 7.

1) Hairline Elasticity Measurement

As the scalp ages, the elasticity of the scalp decreases and the hairline, which is the boundary between the forehead and the head, is struck, and the evaluation method for scalp elasticity was measured by the hairline elasticity. As a measuring device Cutometer CM580 was used and the forehead hairline area was measured.

The measurement was carried out at the same site before and after the use of the hair loss preventing agent, which prevents scalp aging of the present invention, and the R ² (re-deformation force of the skin) value was used as an evaluation data of skin elasticity. The value of R ² is the total elasticity, and the closer to 1, the more elastic the skin is.

As shown in Table 6, it can be seen that Examples 1 to 7 using the hair loss prevention agent that can prevent, relax and prevent scalp aging of the present invention significantly increased the elasticity of the hairline than Comparative Examples 1 and 2. In Comparative Examples 1 and 2, the hair density varied from 98% and 108% before and after 6 months of use, whereas Examples 1-7 increased to 112-147%.

2) Scalp Moisture Specific

Scalp water content was measured using Corneometer CM825 (Courage-Khazaka electronic GmbH, Germany). The measurement was performed three times through the sensor by contacting the corneometer probe with the skin, and the average value was used as an evaluation data for skin moisture content.

Corneometer is basically an insulator for skin, and the more moisture is contained, the more electricity is applied. It measures the capacitance where the probe contacts. Therefore, the moisture content and the capacitance are proportional to each other, and the higher the measured value, the higher the moisture content. It constantly measures water content within 30-40 micrometers down from the stratum corneum of the skin surface, and the unit is arbitrary unit (A.U).

In the human body, the rate of aging accelerates as the water content decreases. In Table 7, the moisture content of some of the compositions of Comparative Examples 1 and 2 was increased than before, but Examples 1 to 7 using the anti-aging hair loss preventing composition of the scalp of the present invention were 300-900% than before. The water content of the scalp increased until.

Combining the results of hair loss prevention efficacy and scalp aging prevention, relaxation and prevention results of Test Examples 1 and 2, the use of the hair loss preventing agent composition of the present invention reduces hair loss, hair thickness and hair density increases, the cause of the scalp Is expected to be due to the relief and improvement of scalp aging, such as an increase in the moisture content and an increase in the elasticity of the hairline.

Claims (6)

As a hair loss preventing cosmetic composition containing menthol, salicylic acid, adenosine, dexpanthenol, and retinol, and having an anti-aging, preventing and preventing scalp effect,
The composition is at least one selected from tocopherol and ascorbic acid; And
Hair loss preventing cosmetic composition for scalp aging further comprising a purple chrysanthemum extract, propolis extract, and jeju jeoldae extract. delete The scalpization of claim 1, wherein the composition comprises 0.05-2% menthol, 0.05-2% salicylic acid, 0.01-0.5% adenosine, and 0.05-15% dexpanthenol, relative to the total weight. Relief hair loss preventer cosmetic composition. The method of claim 1,
The composition is scalp anti-allergic cosmetic composition for scalp mitigation, further comprising one or more additional ingredients selected from collagen, sesame gallium fruit extract, irises root extract, thistle flower / leaf / stem extract, gut extract, and hose pat. The hair loss preventing cosmetic composition of claim 4, wherein the additional component has a total content of 0.01-20% by weight based on the total weight of the composition. Claim 1, wherein the cosmetic composition for preventing hair loss comprising a composition selected from creams, lotions, essences, serums, toners, tonics, and mists.

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