KR101919119B1 - 약학 조성물 - Google Patents

약학 조성물 Download PDF

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KR101919119B1
KR101919119B1 KR1020137010256A KR20137010256A KR101919119B1 KR 101919119 B1 KR101919119 B1 KR 101919119B1 KR 1020137010256 A KR1020137010256 A KR 1020137010256A KR 20137010256 A KR20137010256 A KR 20137010256A KR 101919119 B1 KR101919119 B1 KR 101919119B1
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delete delete
methionine
buffer
antioxidant
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KR20130136467A (ko
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안데르스 닐손
마티아스 맘
카지미에르츠 비스니에프스키
브리타 시크만
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훼링 비.브이.
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    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
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    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
KR1020137010256A 2010-09-30 2011-09-29 약학 조성물 Active KR101919119B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10251690.3 2010-09-30
EP10251690 2010-09-30
PCT/IB2011/002394 WO2012042371A2 (en) 2010-09-30 2011-09-29 Pharmaceutical composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187032634A Division KR102102664B1 (ko) 2010-09-30 2011-09-29 약학 조성물

Publications (2)

Publication Number Publication Date
KR20130136467A KR20130136467A (ko) 2013-12-12
KR101919119B1 true KR101919119B1 (ko) 2018-11-15

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ID=43478408

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020137010256A Active KR101919119B1 (ko) 2010-09-30 2011-09-29 약학 조성물
KR1020187032634A Expired - Fee Related KR102102664B1 (ko) 2010-09-30 2011-09-29 약학 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020187032634A Expired - Fee Related KR102102664B1 (ko) 2010-09-30 2011-09-29 약학 조성물

Country Status (27)

Country Link
US (4) US9566311B2 (https=)
EP (5) EP2621468B1 (https=)
JP (2) JP6038797B2 (https=)
KR (2) KR101919119B1 (https=)
CN (4) CN104906032A (https=)
AU (1) AU2011309762B2 (https=)
BR (2) BR122021001123B1 (https=)
CA (1) CA2812510A1 (https=)
CY (2) CY1119245T1 (https=)
DK (4) DK2621468T3 (https=)
ES (4) ES2905561T3 (https=)
FI (1) FI4374878T3 (https=)
HR (3) HRP20171256T1 (https=)
HU (4) HUE034367T2 (https=)
IL (3) IL225238B (https=)
JO (3) JO3400B1 (https=)
LT (3) LT4374878T (https=)
MX (3) MX395271B (https=)
NZ (1) NZ609719A (https=)
PL (4) PL4374878T3 (https=)
PT (4) PT3222272T (https=)
RS (3) RS66759B1 (https=)
RU (2) RU2737264C2 (https=)
SI (4) SI3222272T1 (https=)
SM (3) SMT202500165T1 (https=)
TW (6) TWI750934B (https=)
WO (1) WO2012042371A2 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070224184A1 (en) * 2006-02-22 2007-09-27 The Research Foundation Of The State University Of New York Method for treating cellulite
JP2015516415A (ja) * 2012-05-08 2015-06-11 ディラフォール・アクチボラゲットDilafor Ab 化学修飾ヘパリンまたはヘパラン硫酸および子宮収縮剤を用いた分娩後出血の処置
ES2970059T3 (es) * 2014-09-19 2024-05-24 Ferring Bv Método de tratamiento del síndrome de Prader-Willi
RU2701199C2 (ru) 2014-10-01 2019-09-25 Окситон Байосайенс Б.В. Перорально распадающаяся твердая фармацевтическая единица дозирования, содержащая контролирующее родовую деятельность вещество
PL3200764T3 (pl) 2014-10-01 2020-12-28 Oxytone Bioscience B.V. Rozpadająca się w jamie ustnej stała farmaceutyczna jednostka dawkowania zawierająca substancję kontrolującą poród
SG11201705591PA (en) 2015-01-07 2017-08-30 Trigemina Inc Magnesium-containing oxytocin formulations and methods of use
WO2016162819A1 (en) * 2015-04-07 2016-10-13 Lupin Limited Stable aqueous pharmaceutical composition of anti-tnf alpha antibody
HUE070412T2 (hu) 2016-04-12 2025-06-28 Tonix Pharma Ltd Magnézium tartalmú oxitocin készítmények és alkamazási eljárásaik
CN107773531B (zh) * 2016-08-31 2021-05-04 成都倍特药业股份有限公司 一种马来酸麦角新碱注射液
CN108236601B (zh) * 2016-12-23 2020-04-17 深圳翰宇药业股份有限公司 一种稳定的含卡贝缩宫素的阴道给药的药用组合物及其制备方法
BR112020001832A2 (pt) * 2017-08-11 2020-07-28 Ferring B.V. método de produção de uma composição farmacêuti-ca
GB201721846D0 (en) * 2017-12-22 2018-02-07 Arecor Ltd Novel composition
EP3759121A1 (en) 2018-03-01 2021-01-06 Trigemina, Inc. Labeled oxytocin and method of manufacture and use
CN108721598B (zh) * 2018-07-03 2020-06-05 北京市新里程医药科技有限公司 一种缩宫素原料的制备方法及其药物组合物和制剂
EP3852724A4 (en) 2018-09-20 2022-07-06 Levo Therapeutics, Inc. CARBETOCIN DRUG PRODUCT AND PROCESS FOR ITS MANUFACTURE
TW202031283A (zh) * 2018-09-20 2020-09-01 馬克 C 曼寧 穩定卡貝縮宮素鼻內製劑
CN109745544B (zh) * 2018-11-23 2024-11-08 南京新百药业有限公司 稳定的缩宫素药物组合物及其制备方法
US20220080023A1 (en) * 2018-12-21 2022-03-17 Arecor Limited Novel composition
JP7390031B2 (ja) * 2018-12-27 2023-12-01 国立大学法人金沢大学 オキシトシン誘導体及びその使用
KR20220011697A (ko) 2019-05-22 2022-01-28 바이오비에 아이앤씨. 테를리프레신 제형
CN110308222A (zh) * 2019-07-17 2019-10-08 武汉赛沃医药科技有限公司 一种卡贝缩宫素原料药有关物质检测方法
CN110403904A (zh) * 2019-07-26 2019-11-05 翔宇药业股份有限公司 卡贝缩宫素注射液及其应用
CN110237230A (zh) * 2019-07-31 2019-09-17 南京康舟医药科技有限公司 一种卡贝缩宫素药物组合物及其制备方法
JP2023500763A (ja) * 2019-11-04 2023-01-11 フェリング ベスローテン フェンノートシャップ 泌乳の改善のためのメロトシンの鼻腔内投与
CN111012739A (zh) * 2019-12-04 2020-04-17 长春圣金诺生物制药有限公司 一种可以常温储存的含卡贝缩宫素及稳定剂的注射液
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CN114712483B (zh) * 2022-05-12 2023-09-29 成都倍特药业股份有限公司 一种麦角新碱缩宫素复方注射液及其制备方法和用途
WO2024211393A2 (en) 2023-04-04 2024-10-10 Tulex Pharmaceuticals Inc. Desmopressin oral compositions

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001185A1 (en) 1993-06-29 1995-01-12 Ferring B.V. Stabilized pharmaceutical peptide compositions
US20010027177A1 (en) 2000-02-04 2001-10-04 Wayne Woodrow Pharmaceutical composition containing a small or medium size peptide
US20030119728A1 (en) 2000-02-16 2003-06-26 Helmut Scheidl Stable, nasally, orally or sublingually applicable pharmaceutical preparation
WO2008042452A1 (en) 2006-09-29 2008-04-10 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions comprising oxytocin or an analog for the treatment of autism
WO2008150305A1 (en) * 2007-06-07 2008-12-11 Nastech Pharmaceutical Company Inc. Intranasal carbetocin formulations and methods for the treatment of autism
WO2009122285A1 (en) 2008-03-31 2009-10-08 Ferring B.V. Oxitocin analogues
EP2174652A2 (en) 2007-08-06 2010-04-14 GP Pharm S.A. Oral pharmaceutical desmopressin composition

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1109558A (zh) * 1994-11-07 1995-10-04 马文亮 装有压力表的双管气筒
SE9604341D0 (sv) * 1996-11-26 1996-11-26 Ferring Bv Hepta-peptide oxytocin analogue
DE69719189T2 (de) 1997-11-18 2003-11-27 Uni-Pharma Kleon Tsetis A.B.E.E., Farmakeftika Ergastiria Pharmazeutische injizierbare Lösungen, die Paracetamol und Kombinationen aus Paracetamol mit anderen Aktivsubstanzen enthalten
US6333313B1 (en) 1998-10-29 2001-12-25 Board Of Regents, The University Of Texas System Clinical use of oxytocin alone or in combination to treat bone disorders
US6894026B1 (en) * 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
JP5290489B2 (ja) 2001-11-08 2013-09-18 アッヴィ・バイオセラピューティクス・インコーポレイテッド Igg抗体の安定な液体医薬製剤
EP1556068B1 (en) 2002-10-03 2010-08-18 Neuropharmacology Services, LLC Oxytocin for use in the treatment of Autism and Asperger's disorder
DE602004019761D1 (de) 2003-01-08 2009-04-16 Novartis Vaccines & Diagnostic Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante
US20100143485A1 (en) 2003-03-05 2010-06-10 Hudnut Paul S Oxycontin controlled release formulations and methods of using same
GT200600031A (es) * 2005-01-28 2006-08-29 Formulacion anticuerpo anti a beta
ES2355196T3 (es) 2007-07-02 2011-03-23 Sime Darby Malaysia Berhad Composición de grasa para la fritura.
JP5643762B2 (ja) * 2008-10-15 2014-12-17 インターシア セラピューティクス,インコーポレイティド 高濃度薬物粒子、製剤、懸濁液、及びこれらの使用

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001185A1 (en) 1993-06-29 1995-01-12 Ferring B.V. Stabilized pharmaceutical peptide compositions
US20010027177A1 (en) 2000-02-04 2001-10-04 Wayne Woodrow Pharmaceutical composition containing a small or medium size peptide
US20030119728A1 (en) 2000-02-16 2003-06-26 Helmut Scheidl Stable, nasally, orally or sublingually applicable pharmaceutical preparation
WO2008042452A1 (en) 2006-09-29 2008-04-10 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions comprising oxytocin or an analog for the treatment of autism
WO2008150305A1 (en) * 2007-06-07 2008-12-11 Nastech Pharmaceutical Company Inc. Intranasal carbetocin formulations and methods for the treatment of autism
EP2174652A2 (en) 2007-08-06 2010-04-14 GP Pharm S.A. Oral pharmaceutical desmopressin composition
WO2009122285A1 (en) 2008-03-31 2009-10-08 Ferring B.V. Oxitocin analogues

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Werner Rath. Prevention of postpartum haemorrhage with oxytocin analogue carbetocin. European journal of Obestet. Gynecol. and Reprod. Biol. 2009, 147(1), pp. 15-20*

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