JP6038797B2 - 医薬組成物 - Google Patents

医薬組成物 Download PDF

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JP6038797B2
JP6038797B2 JP2013530810A JP2013530810A JP6038797B2 JP 6038797 B2 JP6038797 B2 JP 6038797B2 JP 2013530810 A JP2013530810 A JP 2013530810A JP 2013530810 A JP2013530810 A JP 2013530810A JP 6038797 B2 JP6038797 B2 JP 6038797B2
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composition
buffer
carbetocin
antioxidant
methionine
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JP2013543492A5 (https=
JP2013543492A (ja
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ニルソン,アンダース
マルム,マティアス
ウィスニュースキー,カジミエルツ
シークマン,ブリッタ
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フェリング ベスローテン フェンノートシャップ
フェリング ベスローテン フェンノートシャップ
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    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
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    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
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JP2013530810A 2010-09-30 2011-09-29 医薬組成物 Active JP6038797B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10251690.3 2010-09-30
EP10251690 2010-09-30
PCT/IB2011/002394 WO2012042371A2 (en) 2010-09-30 2011-09-29 Pharmaceutical composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016215212A Division JP6250770B2 (ja) 2010-09-30 2016-11-02 医薬組成物

Publications (3)

Publication Number Publication Date
JP2013543492A JP2013543492A (ja) 2013-12-05
JP2013543492A5 JP2013543492A5 (https=) 2014-07-31
JP6038797B2 true JP6038797B2 (ja) 2016-12-07

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ID=43478408

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JP2013530810A Active JP6038797B2 (ja) 2010-09-30 2011-09-29 医薬組成物
JP2016215212A Active JP6250770B2 (ja) 2010-09-30 2016-11-02 医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016215212A Active JP6250770B2 (ja) 2010-09-30 2016-11-02 医薬組成物

Country Status (27)

Country Link
US (4) US9566311B2 (https=)
EP (5) EP2621468B1 (https=)
JP (2) JP6038797B2 (https=)
KR (2) KR101919119B1 (https=)
CN (4) CN104906032A (https=)
AU (1) AU2011309762B2 (https=)
BR (2) BR122021001123B1 (https=)
CA (1) CA2812510A1 (https=)
CY (2) CY1119245T1 (https=)
DK (4) DK2621468T3 (https=)
ES (4) ES2905561T3 (https=)
FI (1) FI4374878T3 (https=)
HR (3) HRP20171256T1 (https=)
HU (4) HUE034367T2 (https=)
IL (3) IL225238B (https=)
JO (3) JO3400B1 (https=)
LT (3) LT4374878T (https=)
MX (3) MX395271B (https=)
NZ (1) NZ609719A (https=)
PL (4) PL4374878T3 (https=)
PT (4) PT3222272T (https=)
RS (3) RS66759B1 (https=)
RU (2) RU2737264C2 (https=)
SI (4) SI3222272T1 (https=)
SM (3) SMT202500165T1 (https=)
TW (6) TWI750934B (https=)
WO (1) WO2012042371A2 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070224184A1 (en) * 2006-02-22 2007-09-27 The Research Foundation Of The State University Of New York Method for treating cellulite
JP2015516415A (ja) * 2012-05-08 2015-06-11 ディラフォール・アクチボラゲットDilafor Ab 化学修飾ヘパリンまたはヘパラン硫酸および子宮収縮剤を用いた分娩後出血の処置
ES2970059T3 (es) * 2014-09-19 2024-05-24 Ferring Bv Método de tratamiento del síndrome de Prader-Willi
RU2701199C2 (ru) 2014-10-01 2019-09-25 Окситон Байосайенс Б.В. Перорально распадающаяся твердая фармацевтическая единица дозирования, содержащая контролирующее родовую деятельность вещество
PL3200764T3 (pl) 2014-10-01 2020-12-28 Oxytone Bioscience B.V. Rozpadająca się w jamie ustnej stała farmaceutyczna jednostka dawkowania zawierająca substancję kontrolującą poród
SG11201705591PA (en) 2015-01-07 2017-08-30 Trigemina Inc Magnesium-containing oxytocin formulations and methods of use
WO2016162819A1 (en) * 2015-04-07 2016-10-13 Lupin Limited Stable aqueous pharmaceutical composition of anti-tnf alpha antibody
HUE070412T2 (hu) 2016-04-12 2025-06-28 Tonix Pharma Ltd Magnézium tartalmú oxitocin készítmények és alkamazási eljárásaik
CN107773531B (zh) * 2016-08-31 2021-05-04 成都倍特药业股份有限公司 一种马来酸麦角新碱注射液
CN108236601B (zh) * 2016-12-23 2020-04-17 深圳翰宇药业股份有限公司 一种稳定的含卡贝缩宫素的阴道给药的药用组合物及其制备方法
BR112020001832A2 (pt) * 2017-08-11 2020-07-28 Ferring B.V. método de produção de uma composição farmacêuti-ca
GB201721846D0 (en) * 2017-12-22 2018-02-07 Arecor Ltd Novel composition
EP3759121A1 (en) 2018-03-01 2021-01-06 Trigemina, Inc. Labeled oxytocin and method of manufacture and use
CN108721598B (zh) * 2018-07-03 2020-06-05 北京市新里程医药科技有限公司 一种缩宫素原料的制备方法及其药物组合物和制剂
EP3852724A4 (en) 2018-09-20 2022-07-06 Levo Therapeutics, Inc. CARBETOCIN DRUG PRODUCT AND PROCESS FOR ITS MANUFACTURE
TW202031283A (zh) * 2018-09-20 2020-09-01 馬克 C 曼寧 穩定卡貝縮宮素鼻內製劑
CN109745544B (zh) * 2018-11-23 2024-11-08 南京新百药业有限公司 稳定的缩宫素药物组合物及其制备方法
US20220080023A1 (en) * 2018-12-21 2022-03-17 Arecor Limited Novel composition
JP7390031B2 (ja) * 2018-12-27 2023-12-01 国立大学法人金沢大学 オキシトシン誘導体及びその使用
KR20220011697A (ko) 2019-05-22 2022-01-28 바이오비에 아이앤씨. 테를리프레신 제형
CN110308222A (zh) * 2019-07-17 2019-10-08 武汉赛沃医药科技有限公司 一种卡贝缩宫素原料药有关物质检测方法
CN110403904A (zh) * 2019-07-26 2019-11-05 翔宇药业股份有限公司 卡贝缩宫素注射液及其应用
CN110237230A (zh) * 2019-07-31 2019-09-17 南京康舟医药科技有限公司 一种卡贝缩宫素药物组合物及其制备方法
JP2023500763A (ja) * 2019-11-04 2023-01-11 フェリング ベスローテン フェンノートシャップ 泌乳の改善のためのメロトシンの鼻腔内投与
CN111012739A (zh) * 2019-12-04 2020-04-17 长春圣金诺生物制药有限公司 一种可以常温储存的含卡贝缩宫素及稳定剂的注射液
ES3010259T3 (en) 2021-03-26 2025-04-01 Ot4B Treatment of dysphagia
CN114191388B (zh) * 2021-12-27 2023-06-09 苏州天马医药集团天吉生物制药有限公司 一种卡贝缩宫素制剂的制备方法
CN114712483B (zh) * 2022-05-12 2023-09-29 成都倍特药业股份有限公司 一种麦角新碱缩宫素复方注射液及其制备方法和用途
WO2024211393A2 (en) 2023-04-04 2024-10-10 Tulex Pharmaceuticals Inc. Desmopressin oral compositions

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482931A (en) * 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
CN1109558A (zh) * 1994-11-07 1995-10-04 马文亮 装有压力表的双管气筒
SE9604341D0 (sv) * 1996-11-26 1996-11-26 Ferring Bv Hepta-peptide oxytocin analogue
DE69719189T2 (de) 1997-11-18 2003-11-27 Uni-Pharma Kleon Tsetis A.B.E.E., Farmakeftika Ergastiria Pharmazeutische injizierbare Lösungen, die Paracetamol und Kombinationen aus Paracetamol mit anderen Aktivsubstanzen enthalten
US6333313B1 (en) 1998-10-29 2001-12-25 Board Of Regents, The University Of Texas System Clinical use of oxytocin alone or in combination to treat bone disorders
US20070032410A1 (en) * 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
US6894026B1 (en) * 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
JP2001233787A (ja) * 2000-02-04 2001-08-28 Patents Exploitation Co Bv 小・中サイズのペプチド含有薬学的組成物
AT409081B (de) 2000-02-16 2002-05-27 Gebro Pharma Gmbh Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung
JP5290489B2 (ja) 2001-11-08 2013-09-18 アッヴィ・バイオセラピューティクス・インコーポレイテッド Igg抗体の安定な液体医薬製剤
EP1556068B1 (en) 2002-10-03 2010-08-18 Neuropharmacology Services, LLC Oxytocin for use in the treatment of Autism and Asperger's disorder
DE602004019761D1 (de) 2003-01-08 2009-04-16 Novartis Vaccines & Diagnostic Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante
US20100143485A1 (en) 2003-03-05 2010-06-10 Hudnut Paul S Oxycontin controlled release formulations and methods of using same
GT200600031A (es) * 2005-01-28 2006-08-29 Formulacion anticuerpo anti a beta
CA2689476C (en) * 2007-06-07 2014-08-05 Nastech Pharmaceutical Company Inc. Intranasal carbetocin formulations and methods for the treatment of autism
ES2355196T3 (es) 2007-07-02 2011-03-23 Sime Darby Malaysia Berhad Composición de grasa para la fritura.
ES2319054B1 (es) * 2007-08-06 2010-02-12 Gp Pharm S.A. Composicion farmaceutica oral de desmopresina.
EP2260053B1 (en) * 2008-03-31 2014-05-14 Ferring BV Oxytocin analogues
JP5643762B2 (ja) * 2008-10-15 2014-12-17 インターシア セラピューティクス,インコーポレイティド 高濃度薬物粒子、製剤、懸濁液、及びこれらの使用

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