KR101894600B1 - 비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제 - Google Patents

비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제 Download PDF

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KR101894600B1
KR101894600B1 KR1020127005935A KR20127005935A KR101894600B1 KR 101894600 B1 KR101894600 B1 KR 101894600B1 KR 1020127005935 A KR1020127005935 A KR 1020127005935A KR 20127005935 A KR20127005935 A KR 20127005935A KR 101894600 B1 KR101894600 B1 KR 101894600B1
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KR20120065342A (ko
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아르투르 미테러
마인하르트 하슬라허
크리스타 마이어
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박스알타 인코퍼레이티드
박스앨타 게엠베하
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020127005935A 2009-08-20 2010-08-20 비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제 Active KR101894600B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23557009P 2009-08-20 2009-08-20
US61/235,570 2009-08-20
PCT/US2010/046180 WO2011022657A1 (en) 2009-08-20 2010-08-20 Purification of vwf for increased removal of non-lipid enveloped viruses

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KR20120065342A KR20120065342A (ko) 2012-06-20
KR101894600B1 true KR101894600B1 (ko) 2018-09-03

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ID=43063204

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KR1020127005935A Active KR101894600B1 (ko) 2009-08-20 2010-08-20 비-지질 외피 바이러스의 증가된 제거를 위한 ｖｗｆ의 정제

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US (1) US9315560B2 (enExample)
EP (1) EP2467399B2 (enExample)
JP (1) JP5838159B2 (enExample)
KR (1) KR101894600B1 (enExample)
CN (2) CN106008697B (enExample)
AU (1) AU2010284116B9 (enExample)
BR (1) BR112012003802B1 (enExample)
CA (1) CA2771232A1 (enExample)
DK (1) DK2467399T3 (enExample)
ES (1) ES2562256T5 (enExample)
HU (1) HUE026907T2 (enExample)
IN (1) IN2012DN01849A (enExample)
MX (1) MX2012002129A (enExample)
NZ (1) NZ598249A (enExample)
PL (1) PL2467399T3 (enExample)
PT (1) PT2467399E (enExample)
SG (2) SG10201408106WA (enExample)
WO (1) WO2011022657A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
KR101772674B1 (ko) 2008-10-21 2017-09-01 박스알타 인코퍼레이티드 동결건조된 재조합 ｖｗｆ 제제
SG11201408490PA (en) * 2012-06-21 2015-01-29 Baxter Int Virus filtration of cell culture media
US9902942B2 (en) 2013-02-22 2018-02-27 Agency For Science, Technology And Research Chromatographic purification of virus preparations with negatively charged particles
DK3152230T3 (da) * 2014-06-06 2019-11-11 Octapharma Ag Præparat omfattende faktor viii og von willebrand-faktor-peptider
DK3158055T3 (da) 2014-06-13 2019-10-14 Csl Ltd Forbedret produktion af recombinant von willebrand-faktor i en bioreaktor
KR20250088663A (ko) 2017-08-23 2025-06-17 체에스엘 베링 게엠베하 폰 빌레브란트 인자의 바이러스 여과 방법
EP3768697A1 (en) 2018-03-21 2021-01-27 Baxalta Incorporated Separation of vwf and vwf propeptide by chromatographic methods
CA3244889A1 (en) 2022-03-08 2023-09-14 Equashield Medical Ltd FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465624B1 (en) 1997-02-27 2002-10-15 Baxter Aktiengesellschaft Purification of von-Willebrand factor by cation exchanger chromatography

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941763A (en) * 1975-03-28 1976-03-02 American Home Products Corporation PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
EP0218692A4 (en) 1985-04-11 1988-03-22 Childrens Medical Center VON WILLEBRAND FACTOR.
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
AT406373B (de) * 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
US6531577B1 (en) † 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
ES2261589T3 (es) * 1998-05-06 2006-11-16 Genentech, Inc. Composicion de anticuerpos anti-her2.
AU2005322067B8 (en) * 2004-12-27 2012-07-26 Takeda Pharmaceutical Company Limited Polymer-von Willebrand factor-conjugates

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465624B1 (en) 1997-02-27 2002-10-15 Baxter Aktiengesellschaft Purification of von-Willebrand factor by cation exchanger chromatography

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Biologicals.,25(4): pp.391-401, 1997.
Thromb Res., 1;105(5), pp.391-400, 2002.
Transfusion and Apheresis Science, 39(1), pp. 75-82, 2008.

Also Published As

Publication number Publication date
DK2467399T3 (en) 2017-01-23
US20110092681A1 (en) 2011-04-21
CN106008697A (zh) 2016-10-12
BR112012003802A2 (pt) 2016-11-22
CN106008697B (zh) 2020-08-04
ES2562256T3 (es) 2016-03-03
AU2010284116B2 (en) 2015-02-12
BR112012003802B1 (pt) 2022-10-25
EP2467399B1 (en) 2015-11-11
NZ598249A (en) 2014-04-30
IN2012DN01849A (enExample) 2015-08-21
EP2467399B2 (en) 2023-02-01
SG178478A1 (en) 2012-04-27
CA2771232A1 (en) 2011-02-24
AU2010284116B9 (en) 2015-03-26
PL2467399T3 (pl) 2016-05-31
JP2013502434A (ja) 2013-01-24
US9315560B2 (en) 2016-04-19
ES2562256T5 (es) 2023-07-20
HUE026907T2 (en) 2016-07-28
WO2011022657A1 (en) 2011-02-24
MX2012002129A (es) 2012-06-08
PT2467399E (pt) 2016-03-18
CN102482341A (zh) 2012-05-30
EP2467399A1 (en) 2012-06-27
JP5838159B2 (ja) 2015-12-24
AU2010284116A1 (en) 2012-03-08
KR20120065342A (ko) 2012-06-20
SG10201408106WA (en) 2015-01-29

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