AU2010284116B9 - Purification of VWF for increased removal of non-lipid enveloped viruses - Google Patents

Purification of VWF for increased removal of non-lipid enveloped viruses Download PDF

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Publication number
AU2010284116B9
AU2010284116B9 AU2010284116A AU2010284116A AU2010284116B9 AU 2010284116 B9 AU2010284116 B9 AU 2010284116B9 AU 2010284116 A AU2010284116 A AU 2010284116A AU 2010284116 A AU2010284116 A AU 2010284116A AU 2010284116 B9 AU2010284116 B9 AU 2010284116B9
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AU
Australia
Prior art keywords
protein
containing solution
cation exchange
exchange resin
vwf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2010284116A
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English (en)
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AU2010284116B2 (en
AU2010284116A1 (en
Inventor
Meinhard Hasslacher
Christa Mayer
Artur Mitterer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of AU2010284116A1 publication Critical patent/AU2010284116A1/en
Publication of AU2010284116B2 publication Critical patent/AU2010284116B2/en
Priority to AU2015201483A priority Critical patent/AU2015201483A1/en
Application granted granted Critical
Publication of AU2010284116B9 publication Critical patent/AU2010284116B9/en
Assigned to Baxalta GmbH, BAXALTA INCORPORATED reassignment Baxalta GmbH Request for Assignment Assignors: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.
Assigned to TAKEDA PHARMACEUTICAL COMPANY LIMITED reassignment TAKEDA PHARMACEUTICAL COMPANY LIMITED Request for Assignment Assignors: Baxalta GmbH, BAXALTA INCORPORATED
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2010284116A 2009-08-20 2010-08-20 Purification of VWF for increased removal of non-lipid enveloped viruses Active AU2010284116B9 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2015201483A AU2015201483A1 (en) 2009-08-20 2015-03-20 Purification of VWF for Increased Removal of Non-Lipid Enveloped Viruses

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23557009P 2009-08-20 2009-08-20
US61/235,570 2009-08-20
PCT/US2010/046180 WO2011022657A1 (en) 2009-08-20 2010-08-20 Purification of vwf for increased removal of non-lipid enveloped viruses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2015201483A Division AU2015201483A1 (en) 2009-08-20 2015-03-20 Purification of VWF for Increased Removal of Non-Lipid Enveloped Viruses

Publications (3)

Publication Number Publication Date
AU2010284116A1 AU2010284116A1 (en) 2012-03-08
AU2010284116B2 AU2010284116B2 (en) 2015-02-12
AU2010284116B9 true AU2010284116B9 (en) 2015-03-26

Family

ID=43063204

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010284116A Active AU2010284116B9 (en) 2009-08-20 2010-08-20 Purification of VWF for increased removal of non-lipid enveloped viruses

Country Status (18)

Country Link
US (1) US9315560B2 (enExample)
EP (1) EP2467399B2 (enExample)
JP (1) JP5838159B2 (enExample)
KR (1) KR101894600B1 (enExample)
CN (2) CN106008697B (enExample)
AU (1) AU2010284116B9 (enExample)
BR (1) BR112012003802B1 (enExample)
CA (1) CA2771232A1 (enExample)
DK (1) DK2467399T3 (enExample)
ES (1) ES2562256T5 (enExample)
HU (1) HUE026907T2 (enExample)
IN (1) IN2012DN01849A (enExample)
MX (1) MX2012002129A (enExample)
NZ (1) NZ598249A (enExample)
PL (1) PL2467399T3 (enExample)
PT (1) PT2467399E (enExample)
SG (2) SG10201408106WA (enExample)
WO (1) WO2011022657A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
KR101772674B1 (ko) 2008-10-21 2017-09-01 박스알타 인코퍼레이티드 동결건조된 재조합 vwf 제제
SG11201408490PA (en) * 2012-06-21 2015-01-29 Baxter Int Virus filtration of cell culture media
US9902942B2 (en) 2013-02-22 2018-02-27 Agency For Science, Technology And Research Chromatographic purification of virus preparations with negatively charged particles
DK3152230T3 (da) * 2014-06-06 2019-11-11 Octapharma Ag Præparat omfattende faktor viii og von willebrand-faktor-peptider
DK3158055T3 (da) 2014-06-13 2019-10-14 Csl Ltd Forbedret produktion af recombinant von willebrand-faktor i en bioreaktor
KR20250088663A (ko) 2017-08-23 2025-06-17 체에스엘 베링 게엠베하 폰 빌레브란트 인자의 바이러스 여과 방법
EP3768697A1 (en) 2018-03-21 2021-01-27 Baxalta Incorporated Separation of vwf and vwf propeptide by chromatographic methods
CA3244889A1 (en) 2022-03-08 2023-09-14 Equashield Medical Ltd FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941763A (en) * 1975-03-28 1976-03-02 American Home Products Corporation PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
EP0218692A4 (en) 1985-04-11 1988-03-22 Childrens Medical Center VON WILLEBRAND FACTOR.
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
AT406373B (de) * 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT405403B (de) * 1997-02-27 1999-08-25 Immuno Ag Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
US6531577B1 (en) 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
ES2261589T3 (es) * 1998-05-06 2006-11-16 Genentech, Inc. Composicion de anticuerpos anti-her2.
AU2005322067B8 (en) * 2004-12-27 2012-07-26 Takeda Pharmaceutical Company Limited Polymer-von Willebrand factor-conjugates

Also Published As

Publication number Publication date
DK2467399T3 (en) 2017-01-23
US20110092681A1 (en) 2011-04-21
CN106008697A (zh) 2016-10-12
BR112012003802A2 (pt) 2016-11-22
CN106008697B (zh) 2020-08-04
ES2562256T3 (es) 2016-03-03
AU2010284116B2 (en) 2015-02-12
BR112012003802B1 (pt) 2022-10-25
EP2467399B1 (en) 2015-11-11
NZ598249A (en) 2014-04-30
IN2012DN01849A (enExample) 2015-08-21
EP2467399B2 (en) 2023-02-01
SG178478A1 (en) 2012-04-27
CA2771232A1 (en) 2011-02-24
PL2467399T3 (pl) 2016-05-31
JP2013502434A (ja) 2013-01-24
US9315560B2 (en) 2016-04-19
KR101894600B1 (ko) 2018-09-03
ES2562256T5 (es) 2023-07-20
HUE026907T2 (en) 2016-07-28
WO2011022657A1 (en) 2011-02-24
MX2012002129A (es) 2012-06-08
PT2467399E (pt) 2016-03-18
CN102482341A (zh) 2012-05-30
EP2467399A1 (en) 2012-06-27
JP5838159B2 (ja) 2015-12-24
AU2010284116A1 (en) 2012-03-08
KR20120065342A (ko) 2012-06-20
SG10201408106WA (en) 2015-01-29

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Legal Events

Date Code Title Description
SREP Specification republished
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: BAXALTA GMBH; BAXALTA INCORPORATED

Free format text: FORMER OWNER WAS: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE S.A.

PC Assignment registered

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Free format text: FORMER OWNER(S): BAXALTA INCORPORATED; BAXALTA GMBH