CN106008697B - 纯化vwf以增加非-脂质包封的病毒的去除 - Google Patents
纯化vwf以增加非-脂质包封的病毒的去除 Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- Public Health (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| CN2010800395824A CN102482341A (zh) | 2009-08-20 | 2010-08-20 | 纯化vwf以增加非-脂质包封的病毒的去除 |
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| CN2010800395824A Division CN102482341A (zh) | 2009-08-20 | 2010-08-20 | 纯化vwf以增加非-脂质包封的病毒的去除 |
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| CN106008697A CN106008697A (zh) | 2016-10-12 |
| CN106008697B true CN106008697B (zh) | 2020-08-04 |
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| CN2010800395824A Pending CN102482341A (zh) | 2009-08-20 | 2010-08-20 | 纯化vwf以增加非-脂质包封的病毒的去除 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11197916B2 (en) | 2007-12-28 | 2021-12-14 | Takeda Pharmaceutical Company Limited | Lyophilized recombinant VWF formulations |
| DK2349314T3 (da) * | 2008-10-21 | 2013-05-27 | Baxter Int | Lyofiliserede præparater af rekombinant VWF |
| MX386767B (es) * | 2012-06-21 | 2025-03-19 | Takeda Pharmaceuticals Co | Filtración de virus de medio de cultivo celular. |
| US9902942B2 (en) | 2013-02-22 | 2018-02-27 | Agency For Science, Technology And Research | Chromatographic purification of virus preparations with negatively charged particles |
| CA2949323A1 (en) * | 2014-06-06 | 2015-12-10 | Octapharma Ag | Preparation comprising factor viii and von willebrand factor peptides |
| CN106414719B (zh) | 2014-06-13 | 2020-02-14 | 杰特有限公司 | 生物反应器中重组von Willebrand因子的改进生产 |
| BR112020002234A2 (pt) | 2017-08-23 | 2020-07-28 | Csl Behring Gmbh | método para a filtragem de virus do fator von willebrand |
| SG11202009213TA (en) | 2018-03-21 | 2020-10-29 | Baxalta Inc | Separation of vwf and vwf propeptide by chromatographic methods |
| WO2023170680A1 (en) | 2022-03-08 | 2023-09-14 | Equashield Medical Ltd | Fluid transfer station in a robotic pharmaceutical preparation system |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1191545A (zh) * | 1995-05-25 | 1998-08-26 | 达尔塔生物工艺有限公司 | 高纯度白蛋白生产方法 |
| CN101333244A (zh) * | 1998-05-06 | 2008-12-31 | 基因技术股份有限公司 | 用离子交换层析纯化蛋白质 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3941763A (en) | 1975-03-28 | 1976-03-02 | American Home Products Corporation | PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates |
| WO1986006096A1 (en) | 1985-04-11 | 1986-10-23 | The Children's Medical Center Corporation | Von willebrand factor |
| AT406373B (de) * | 1997-02-27 | 2000-04-25 | Immuno Ag | Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie |
| AT405403B (de) * | 1997-02-27 | 1999-08-25 | Immuno Ag | Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie |
| AT405485B (de) | 1997-05-28 | 1999-08-25 | Immuno Ag | Eine das vwf-propeptid enthaltende pharmazeutische präparation |
| US6531577B1 (en) † | 1997-12-15 | 2003-03-11 | Hemasure Denmark A/S | von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations |
| BRPI0519562A2 (pt) | 2004-12-27 | 2009-01-27 | Baxter Int | construÇço proteinÁcea, complexo, mÉtodo para prolongar a meia-vida in vivo de fator viii (fviii) ou um derivado biologicamente ativo do mesmo composiÇço farmacÊutica, e, mÉtodo para formar uma construÇço proteinÁcea |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1191545A (zh) * | 1995-05-25 | 1998-08-26 | 达尔塔生物工艺有限公司 | 高纯度白蛋白生产方法 |
| CN101333244A (zh) * | 1998-05-06 | 2008-12-31 | 基因技术股份有限公司 | 用离子交换层析纯化蛋白质 |
Non-Patent Citations (1)
| Title |
|---|
| The removal of model viruses, Poliovirus type 1 and Canine Parvovirus, during the purification of human albumin using ion-exchange chromatographic procedures;Rachel Cameron et al.;《Journal of the international association of biological standardization》;19971231;第25卷(第4期);391-401 * |
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|---|---|
| KR101894600B1 (ko) | 2018-09-03 |
| SG178478A1 (en) | 2012-04-27 |
| MX2012002129A (es) | 2012-06-08 |
| HUE026907T2 (en) | 2016-07-28 |
| JP2013502434A (ja) | 2013-01-24 |
| WO2011022657A1 (en) | 2011-02-24 |
| JP5838159B2 (ja) | 2015-12-24 |
| EP2467399B1 (en) | 2015-11-11 |
| AU2010284116B9 (en) | 2015-03-26 |
| DK2467399T3 (en) | 2017-01-23 |
| NZ598249A (en) | 2014-04-30 |
| PL2467399T3 (pl) | 2016-05-31 |
| IN2012DN01849A (enExample) | 2015-08-21 |
| KR20120065342A (ko) | 2012-06-20 |
| CA2771232A1 (en) | 2011-02-24 |
| BR112012003802B1 (pt) | 2022-10-25 |
| AU2010284116B2 (en) | 2015-02-12 |
| BR112012003802A2 (pt) | 2016-11-22 |
| ES2562256T3 (es) | 2016-03-03 |
| AU2010284116A1 (en) | 2012-03-08 |
| EP2467399B2 (en) | 2023-02-01 |
| CN106008697A (zh) | 2016-10-12 |
| CN102482341A (zh) | 2012-05-30 |
| PT2467399E (pt) | 2016-03-18 |
| ES2562256T5 (es) | 2023-07-20 |
| US20110092681A1 (en) | 2011-04-21 |
| SG10201408106WA (en) | 2015-01-29 |
| EP2467399A1 (en) | 2012-06-27 |
| US9315560B2 (en) | 2016-04-19 |
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