KR101892764B1 - 경피 접착제 조성물, 디바이스, 및 방법 - Google Patents

경피 접착제 조성물, 디바이스, 및 방법 Download PDF

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Publication number
KR101892764B1
KR101892764B1 KR1020137004235A KR20137004235A KR101892764B1 KR 101892764 B1 KR101892764 B1 KR 101892764B1 KR 1020137004235 A KR1020137004235 A KR 1020137004235A KR 20137004235 A KR20137004235 A KR 20137004235A KR 101892764 B1 KR101892764 B1 KR 101892764B1
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KR
South Korea
Prior art keywords
acrylate
delete delete
adhesive
reaction product
polymerization reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020137004235A
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English (en)
Korean (ko)
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KR20130143001A (ko
Inventor
제임스 피 디지오
엘리자베쓰 이 존슨
정 즈 우
프린스 에이미 프레스즐러
Original Assignee
쓰리엠 이노베이티브 프로퍼티즈 컴파니
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Publication of KR20130143001A publication Critical patent/KR20130143001A/ko
Application granted granted Critical
Publication of KR101892764B1 publication Critical patent/KR101892764B1/ko
Assigned to 킨데바 드러그 딜리버리 엘.피. reassignment 킨데바 드러그 딜리버리 엘.피. 권리의 전부이전등록 Assignors: 쓰리엠 이노베이티브 프로퍼티즈 컴파니
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C08F220/1808—C8-(meth)acrylate, e.g. isooctyl (meth)acrylate or 2-ethylhexyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C09J133/08—Homopolymers or copolymers of acrylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C09J133/10—Homopolymers or copolymers of methacrylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J4/00—Adhesives based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond ; adhesives, based on monomers of macromolecular compounds of groups C09J183/00 - C09J183/16
    • C09J4/06—Organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond in combination with a macromolecular compound other than an unsaturated polymer of groups C09J159/00 - C09J187/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020137004235A 2010-07-21 2011-07-19 경피 접착제 조성물, 디바이스, 및 방법 Expired - Fee Related KR101892764B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36635810P 2010-07-21 2010-07-21
US61/366,358 2010-07-21
PCT/US2011/044522 WO2012012417A1 (en) 2010-07-21 2011-07-19 Transdermal adhesive compositions, devices, and methods

Publications (2)

Publication Number Publication Date
KR20130143001A KR20130143001A (ko) 2013-12-30
KR101892764B1 true KR101892764B1 (ko) 2018-08-28

Family

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KR1020137004235A Expired - Fee Related KR101892764B1 (ko) 2010-07-21 2011-07-19 경피 접착제 조성물, 디바이스, 및 방법

Country Status (12)

Country Link
US (3) US9375510B2 (enExample)
EP (2) EP2596071B1 (enExample)
JP (3) JP2013537526A (enExample)
KR (1) KR101892764B1 (enExample)
CN (1) CN103068944B (enExample)
BR (1) BR112013001550A2 (enExample)
CA (1) CA2806183C (enExample)
ES (1) ES2720952T3 (enExample)
MX (1) MX346041B (enExample)
SG (2) SG10201505658RA (enExample)
WO (1) WO2012012417A1 (enExample)
ZA (1) ZA201301336B (enExample)

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WO2011053251A1 (en) 2009-10-30 2011-05-05 Ix Biopharma Pte Ltd Fast dissolving solid dosage form
US12186426B2 (en) 2009-10-30 2025-01-07 Ix Biopharma Ltd. Solid dosage form
EP2596071B1 (en) * 2010-07-21 2019-02-13 3M Innovative Properties Company Transdermal adhesive compositions, devices, and methods
US9333182B2 (en) * 2011-08-31 2016-05-10 Sekisui Medical Co., Ltd. Adhesive patch
US20140083878A1 (en) * 2012-09-21 2014-03-27 Mylan Inc. Transdermal drug delivery device
WO2014111790A2 (en) 2013-01-15 2014-07-24 Zydus Technologies Limited Stable transdermal pharmaceutical drug delivery system comprising rivastigmine
WO2016100708A1 (en) * 2014-12-19 2016-06-23 3M Innovative Properties Company Transdermal drug delivery device including fentanyl
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
KR102565565B1 (ko) 2015-02-06 2023-08-09 노벤 파머수티컬즈, 인코퍼레이티드 경피 약물 전달용 감압 접착제
JP2019206497A (ja) * 2018-05-30 2019-12-05 小林製薬株式会社 外用医薬組成物
WO2020084380A1 (en) 2018-10-23 2020-04-30 3M Innovative Properties Company Tamper evident transdermal patch
DE102019120403A1 (de) * 2019-07-29 2021-02-04 Lts Lohmann Therapie-Systeme Ag Verfahren zur Herstellung von Haftklebemassen zur Verwendung in einem transdermalen therapeutischen System
CN117202878A (zh) 2020-04-30 2023-12-08 金德瓦药物控释有限公司 粘合剂制品及其制备方法
CA3189066A1 (en) 2020-07-06 2022-01-13 Kindeva Drug Delivery L.P. Drug delivery device including patch segments
EP4633720A1 (en) 2022-12-16 2025-10-22 Kindeva Drug Delivery L.P. Drug delivery device
US20260135420A1 (en) * 2024-11-14 2026-05-14 Fukuta Electric & Machinery Co., Ltd. Stator structure with flat wire windings

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JP2000053564A (ja) 1998-08-07 2000-02-22 Toagosei Co Ltd パップ剤及びその製造方法
WO2005004090A1 (en) 2003-07-08 2005-01-13 Comes Alive Internation, Inc. Method of and means for teaching accounting concepts and procedures
JP2008517142A (ja) * 2004-10-19 2008-05-22 スリーエム イノベイティブ プロパティズ カンパニー 感圧接着剤の製造方法

Also Published As

Publication number Publication date
CA2806183C (en) 2019-01-08
EP2596071B1 (en) 2019-02-13
CA2806183A1 (en) 2012-01-26
EP3517105A1 (en) 2019-07-31
ES2720952T3 (es) 2019-07-25
CN103068944B (zh) 2016-03-09
EP3517105B1 (en) 2021-04-28
JP2016029093A (ja) 2016-03-03
US10376473B2 (en) 2019-08-13
ZA201301336B (en) 2014-02-26
US10034840B2 (en) 2018-07-31
MX346041B (es) 2017-03-03
MX2013000861A (es) 2013-04-03
US20180325838A1 (en) 2018-11-15
BR112013001550A2 (pt) 2016-05-24
SG187158A1 (en) 2013-02-28
JP6280091B2 (ja) 2018-02-14
EP2596071A1 (en) 2013-05-29
WO2012012417A1 (en) 2012-01-26
JP2013537526A (ja) 2013-10-03
US20130122079A1 (en) 2013-05-16
US9375510B2 (en) 2016-06-28
SG10201505658RA (en) 2015-09-29
EP3517105B8 (en) 2021-06-23
US20160271074A1 (en) 2016-09-22
KR20130143001A (ko) 2013-12-30
CN103068944A (zh) 2013-04-24
JP2018052992A (ja) 2018-04-05

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