KR101867634B1 - 시그마 수용체-매개 장애를 치료하기 위한 시클릭 아미드 유도체의 사용 방법 - Google Patents

시그마 수용체-매개 장애를 치료하기 위한 시클릭 아미드 유도체의 사용 방법 Download PDF

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KR101867634B1
KR101867634B1 KR1020137004218A KR20137004218A KR101867634B1 KR 101867634 B1 KR101867634 B1 KR 101867634B1 KR 1020137004218 A KR1020137004218 A KR 1020137004218A KR 20137004218 A KR20137004218 A KR 20137004218A KR 101867634 B1 KR101867634 B1 KR 101867634B1
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treatment
schizophrenia
sigma
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KR20130129906A (ko
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레미 헨리 루쓰링거
로렌조 펠레그리니
아제리스 엔. 카라벨라스
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미쓰비시 타나베 파마 코퍼레이션
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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

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KR1020137004218A 2010-07-20 2011-07-20 시그마 수용체-매개 장애를 치료하기 위한 시클릭 아미드 유도체의 사용 방법 Active KR101867634B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36608010P 2010-07-20 2010-07-20
US61/366,080 2010-07-20
PCT/US2011/044698 WO2012012543A1 (en) 2010-07-20 2011-07-20 Methods of use cyclic amide derivatives to treat sigma receptor-mediated disorders

Publications (2)

Publication Number Publication Date
KR20130129906A KR20130129906A (ko) 2013-11-29
KR101867634B1 true KR101867634B1 (ko) 2018-06-15

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EP (2) EP2595485B1 (enExample)
JP (3) JP2013531073A (enExample)
KR (1) KR101867634B1 (enExample)
CN (2) CN103108548A (enExample)
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CA (2) CA2805904C (enExample)
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US8937900B2 (en) 2010-07-20 2015-01-20 Qualcomm Incorporated Enhancing pilot channel transmission in TD-SCDMA multicarrier systems using secondary carrier frequencies
US10179776B2 (en) 2014-06-09 2019-01-15 Intra-Cellular Therapies, Inc. Compounds and methods of use to treat schizophrenia
JP2018501217A (ja) * 2014-12-02 2018-01-18 田辺三菱製薬株式会社 統合失調症を治療するための２−（（１−（２（４−フルオロフェニル）−２−オキソエチル）ピペリジン−４−イル）メチル）イソインドリン−１−オン
WO2017205393A1 (en) * 2016-05-25 2017-11-30 Minerva Neurosciences, Inc. Compositions and methods for treating negative symptoms in non-schizophrenic patients
PE20200732A1 (es) 2017-06-21 2020-07-23 Minerva Neurosciences Inc Formas de dosificacion oral y de liberacion controlada gastrorresistentes
GB2591667A (en) * 2018-08-21 2021-08-04 Minerva Neurosciences Inc Use of roluperidone to treat negative symptoms and disorders, increase neuroplasticity, and promote neuroprotection
WO2021236879A1 (en) 2020-05-20 2021-11-25 The Board Of Trustees Of The University Of Illinois Method for treating lysosomal storage diseases with histatin peptides

Citations (1)

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US7166617B2 (en) * 2000-02-29 2007-01-23 Mitsubishi Pharma Corporation Cyclic amide derivatives

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ZA908641B (en) * 1989-10-27 1992-06-24 Du Pont (n-phthalimidoalkyl)piperidines
IE903857A1 (en) * 1989-10-27 1991-05-08 Du Pont Merck Pharma (N-Phthalimidoalkyl)Piperidines
KR100259107B1 (ko) * 1992-04-23 2000-07-01 슈테펜 엘. 네스비트 세로토닌 5ht₂길항제로서의 4-이미도메틸-1-[2'-페닐-2'-옥소에틸]피페리딘, 이의 제조방법 및 이를 포함하는 약제학적 조성물
TW200817400A (en) * 2006-05-30 2008-04-16 Elbion Ag Pyrido [3,2-e] pyrazines, their use as inhibitors of phosphodiesterase 10, and processes for preparing them

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US7166617B2 (en) * 2000-02-29 2007-01-23 Mitsubishi Pharma Corporation Cyclic amide derivatives

Non-Patent Citations (1)

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Title
Schizophrenia Research Volume 61, Issues 2-3, 1 June 2003. pages 123-136 *

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CN107007603A (zh) 2017-08-04
PT2595485T (pt) 2022-05-30
US20250228838A1 (en) 2025-07-17
EP4070794A2 (en) 2022-10-12
EP4070794A3 (en) 2023-01-18
CA2805904C (en) 2022-06-21
US20210106573A1 (en) 2021-04-15
RU2017105262A3 (enExample) 2019-01-18
RU2017105262A (ru) 2019-01-18
JP2018065829A (ja) 2018-04-26
CN103108548A (zh) 2013-05-15
TW201211022A (en) 2012-03-16
EP2595485A1 (en) 2013-05-29
EP2595485B1 (en) 2022-03-16
JP2013531073A (ja) 2013-08-01
RU2746871C2 (ru) 2021-04-21
KR20130129906A (ko) 2013-11-29
RU2613201C2 (ru) 2017-03-15
JP2016199578A (ja) 2016-12-01
BR112013001302A2 (pt) 2017-07-04
ES2914120T3 (es) 2022-06-07
TWI520949B (zh) 2016-02-11
EP2595485A4 (en) 2014-04-23
CA3154027A1 (en) 2012-01-26
RU2013107378A (ru) 2014-08-27
US20160354357A1 (en) 2016-12-08
WO2012012543A1 (en) 2012-01-26
JP6419294B2 (ja) 2018-11-07
US20130274290A1 (en) 2013-10-17
CA2805904A1 (en) 2012-01-26
PL2595485T3 (pl) 2022-06-20
HUE058736T2 (hu) 2022-09-28
DK2595485T3 (da) 2022-05-30

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