KR101860266B1 - 트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 피부상처 치료용 조성물 - Google Patents

트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 피부상처 치료용 조성물 Download PDF

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KR101860266B1
KR101860266B1 KR1020170080366A KR20170080366A KR101860266B1 KR 101860266 B1 KR101860266 B1 KR 101860266B1 KR 1020170080366 A KR1020170080366 A KR 1020170080366A KR 20170080366 A KR20170080366 A KR 20170080366A KR 101860266 B1 KR101860266 B1 KR 101860266B1
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exosome
thrombin
stem cells
derived
factor
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KR20180003999A (ko
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장윤실
박원순
성동경
안소윤
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사회복지법인 삼성생명공익재단
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Priority to JP2018568285A priority Critical patent/JP6826135B2/ja
Priority to EP17820513.4A priority patent/EP3479831B1/en
Priority to CN201780047575.0A priority patent/CN109641013B/zh
Priority to US16/314,725 priority patent/US12239695B2/en
Priority to PCT/KR2017/006776 priority patent/WO2018004237A1/ko
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    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • A61K35/48—Reproductive organs
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    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells

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KR1020170080366A 2016-07-01 2017-06-26 트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 피부상처 치료용 조성물 Active KR101860266B1 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2018568285A JP6826135B2 (ja) 2016-07-01 2017-06-27 トロンビン処理幹細胞に由来するエクソソームを含む皮膚傷治療用組成物
EP17820513.4A EP3479831B1 (en) 2016-07-01 2017-06-27 Composition comprising thrombin-treated stem cell-derived exosome for use in treating skin wound
CN201780047575.0A CN109641013B (zh) 2016-07-01 2017-06-27 包含凝血酶处理干细胞来源的外泌体的皮肤创伤的治疗用组合物
US16/314,725 US12239695B2 (en) 2016-07-01 2017-06-27 Composition comprising thrombin-treated stem cell-derived exosome for treating skin wound
PCT/KR2017/006776 WO2018004237A1 (ko) 2016-07-01 2017-06-27 트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 피부상처 치료용 조성물

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Application Number Priority Date Filing Date Title
KR20160083703 2016-07-01
KR1020160083703 2016-07-01

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KR20180003999A KR20180003999A (ko) 2018-01-10
KR101860266B1 true KR101860266B1 (ko) 2018-05-24

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US (1) US12239695B2 (enExample)
EP (1) EP3479831B1 (enExample)
JP (1) JP6826135B2 (enExample)
KR (1) KR101860266B1 (enExample)
CN (1) CN109641013B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020022541A1 (ko) 2018-07-27 2020-01-30 주식회사 엑소스템텍 엑소좀을 유효성분으로 포함하는 급성 간부전의 예방 또는 치료용 조성물
KR20200012713A (ko) 2018-07-27 2020-02-05 주식회사 엑소스템텍 엑소좀을 유효성분으로 포함하는 급성 간질환의 예방 또는 치료용 조성물
KR102159394B1 (ko) * 2019-10-04 2020-09-24 (주)에스디생명공학 바다제비집에서 유래된 엑소좀을 유효성분으로 포함하는 피부 상태 개선용 조성물

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KR101973284B1 (ko) 2017-01-16 2019-04-29 사회복지법인 삼성생명공익재단 신생아 ｈｉｅ 치료용 조성물
KR102323056B1 (ko) * 2019-05-02 2021-11-09 에스씨엠생명과학 주식회사 hPL 함유 배지에서 배양된 중간엽 줄기세포의 배양액을 포함하는 화장료 조성물
US12491212B2 (en) 2019-11-12 2025-12-09 Brexogen Inc. Composition for preventing or treating renal diseases, comprising exosomes derived from precursor cells of induced pluripotent stem cell-derived mesenchymal stem cells
JP2021116228A (ja) * 2020-01-22 2021-08-10 医薬資源研究所株式会社 抗酸化ストレス剤、化粧品、および医薬品
US12077780B2 (en) 2020-02-14 2024-09-03 Allergan Sales, Llc Conditioned medium from cells cultured under hypoxic conditions and uses thereof
KR20210127510A (ko) * 2020-04-14 2021-10-22 사회복지법인 삼성생명공익재단 트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 당뇨병성 피부질환 예방 또는 치료용 조성물
CN111888379A (zh) * 2020-08-17 2020-11-06 济宁医学院附属医院 干细胞来源的微囊泡在制备修复瘢痕的制剂中的应用
EP4252761A4 (en) * 2020-11-26 2024-06-05 Samsung Life Public Welfare Foundation COMPOSITION FOR THE TREATMENT OF INFECTIOUS DISEASES, COMPRISING EXOSOMES DERIVED FROM THROMBIN-PROCESSED STEM CELLS
CN114904043B (zh) * 2022-04-28 2023-07-21 深圳市儿童医院 复合水凝胶及其制备方法和应用
JP2025539861A (ja) * 2022-11-25 2025-12-09 エルピス・セル・セラピューティクス ｖＭＳＣのセクレトームおよびその用途

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020022541A1 (ko) 2018-07-27 2020-01-30 주식회사 엑소스템텍 엑소좀을 유효성분으로 포함하는 급성 간부전의 예방 또는 치료용 조성물
KR20200012713A (ko) 2018-07-27 2020-02-05 주식회사 엑소스템텍 엑소좀을 유효성분으로 포함하는 급성 간질환의 예방 또는 치료용 조성물
KR102159394B1 (ko) * 2019-10-04 2020-09-24 (주)에스디생명공학 바다제비집에서 유래된 엑소좀을 유효성분으로 포함하는 피부 상태 개선용 조성물

Also Published As

Publication number Publication date
CN109641013B (zh) 2022-07-26
EP3479831A1 (en) 2019-05-08
JP2019520365A (ja) 2019-07-18
EP3479831A4 (en) 2020-03-25
KR20180003999A (ko) 2018-01-10
CN109641013A (zh) 2019-04-16
JP6826135B2 (ja) 2021-02-03
US20190314469A1 (en) 2019-10-17
US12239695B2 (en) 2025-03-04
EP3479831B1 (en) 2022-06-15

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